Aliases for FOXE3 Gene
External Ids for FOXE3 Gene
Previous HGNC Symbols for FOXE3 Gene
Previous GeneCards Identifiers for FOXE3 Gene
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia. [provided by RefSeq, Dec 2009]
GeneCards Summary for FOXE3 Gene
FOXE3 (Forkhead Box E3) is a Protein Coding gene. Diseases associated with FOXE3 include aphakia, congenital primary and foxe3-related anterior segment mesenchymal dysgenesis. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and transcription factor binding. An important paralog of this gene is FOXC1.
UniProtKB/Swiss-Prot for FOXE3 Gene
Transcription factor activator.