Aliases for FANCB Gene
External Ids for FANCB Gene
Previous GeneCards Identifiers for FANCB Gene
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
GeneCards Summary for FANCB Gene
FANCB (Fanconi Anemia, Complementation Group B) is a Protein Coding gene. Diseases associated with FANCB include fanconi anemia, complementation group b and vacterl with hydrocephalus, fancb-related. Among its related pathways are DNA Damage and DNA Double-Strand Break Repair.
UniProtKB/Swiss-Prot for FANCB Gene
DNA repair protein required for FANCD2 ubiquitination.