Aliases for CTRC Gene
External Ids for CTRC Gene
Previous GeneCards Identifiers for CTRC Gene
This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for CTRC Gene
CTRC (Chymotrypsin C (Caldecrin)) is a Protein Coding gene. Diseases associated with CTRC include ctrc-related hereditary pancreatitis and tropical pancreatitis. Among its related pathways are Metabolism and Metabolism of vitamins and cofactors. GO annotations related to this gene include serine-type endopeptidase activity and peptidase activity. An important paralog of this gene is CELA2B.
UniProtKB/Swiss-Prot for CTRC Gene
Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity.