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ZZZ3 Gene

protein-coding   GIFtS: 50
GCID: GC01M078028

Zinc Finger, ZZ-Type Containing 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger, ZZ-Type Containing 31 2
ATAC Component 1 Homolog (Drosophila)1
ATAC12
ATAC Component 1 Homolog2
Zinc Finger, ZZ Domain Containing 32
ZZ-Type Zinc Finger-Containing Protein 32

External Ids:    HGNC: 245231   Entrez Gene: 260092   Ensembl: ENSG000000365497   UniProtKB: Q8IYH53   

Export aliases for ZZZ3 gene to outside databases

Previous GC identifers: GC01M077452 GC01M077450 GC01M077742 GC01M076161


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZZZ3 Gene:
ZZZ3 (zinc finger, ZZ-type containing 3) is a protein-coding gene. Diseases associated with ZZZ3 include breast and colorectal cancer, and colorectal cancer. GO annotations related to this gene include chromatin binding.

UniProtKB/Swiss-Prot: ZZZ3_HUMAN, Q8IYH5
Function: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4

Gene Wiki entry for ZZZ3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZZZ3 gene promoter:
         Elk-1   USF1   GATA-3   Nkx2-5   NF-AT   GATA-1   GATA-2   USF-1   HFH-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ZZZ3 promoter sequence
   Search Chromatin IP Primers for ZZZ3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZZZ3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p31.1   Ensembl cytogenetic band:  1p31.1   HGNC cytogenetic band: 1p31.1

ZZZ3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZZZ3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M078028:  view genomic region     (about GC identifiers)

Start:
78,028,101 bp from pter      End:
78,149,104 bp from pter
Size:
121,004 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZZZ3_HUMAN, Q8IYH5 (See protein sequence)
Recommended Name: ZZ-type zinc finger-containing protein 3  
Size: 903 amino acids; 102023 Da
Subunit: Component of the ADA2A-containing complex (ATAC), composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP,
WDR5, YEATS2, CCDC101 and DR1
2 PDB 3D structures from and Proteopedia for ZZZ3:
2FC7 (3D)        2YUM (3D)    
Secondary accessions: B7WPC6 Q6N004 Q6N070 Q8IYP0 Q8IYR1 Q8TEK4 Q9Y4U0
Alternative splicing: 4 isoforms:  Q8IYH5-1   Q8IYH5-2   Q8IYH5-3   Q8IYH5-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZZZ3: NX_Q8IYH5

Explore proteomics data for ZZZ3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZZZ3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056349.1  
    ENSEMBL proteins: 
     ENSP00000359837   ENSP00000359834   ENSP00000393779   ENSP00000392408  
    Reactome Protein details: Q8IYH5

    ZZZ3 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for ZZZ3
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    Novus Biologicals ZZZ3 Protein
    Novus Biologicals ZZZ3 Lysate
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    Cloud-Clone Corp. Proteins for ZZZ3

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    Cloud-Clone Corp. CLIAs for ZZZ3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZZZ: Zinc fingers, ZZ-type

    4 InterPro protein domains:
     IPR001005 SANT/Myb
     IPR017930 Myb_dom
     IPR009057 Homeodomain-like
     IPR000433 Znf_ZZ

    Graphical View of Domain Structure for InterPro Entry Q8IYH5

    ProtoNet protein and cluster: Q8IYH5

    2 Blocks protein domains:
    IPB000433 Zn-finger
    IPB001005 Myb DNA-binding domain


    UniProtKB/Swiss-Prot: ZZZ3_HUMAN, Q8IYH5
    Similarity: Contains 1 HTH myb-type DNA-binding domain
    Similarity: Contains 1 ZZ-type zinc finger


    ZZZ3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZZZ3_HUMAN, Q8IYH5
    Function: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003682chromatin binding IEA--
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding IEA--
         
    ZZZ3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ZZZ3:
     Synthetic lethal with Ras 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Zzz3):
     mortality/aging 

    ZZZ3 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZZZ3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZZZ3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZZZ3

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ZZZ3 (see all 70):
    hsa-miR-323-3p hsa-miR-520f hsa-miR-128 hsa-miR-3653 hsa-miR-342-3p hsa-miR-298 hsa-miR-556-3p hsa-miR-27a
    SwitchGear 3'UTR luciferase reporter plasmidZZZ3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZZZ3

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    GenScript: all cDNA clones in your preferred vector: ZZZ3 (NM_015534)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZZZ3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZZZ3

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZZZ3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZZZ3_HUMAN, Q8IYH5: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005671Ada2/Gcn5/Ada3 transcription activator complex IEA--

    ZZZ3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZZZ3 About    
    See pathways by source

    SuperPathContained pathways About
    1RNA Polymerase I Promoter Opening
    HATs acetylate histones0.34
    Chromatin organization0.34
    Chromatin modifying enzymes0.34

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ZZZ3
        HATs acetylate histones



    ZZZ3 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZZZ3
    Interactions:

        Search GeneGlobe Interaction Network for ZZZ3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ZZZ3 (Q8IYH51, 2, 3 ENSP000003598374) via UniProtKB, MINT, STRING, and/or I2D (see all 76)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KAT2AQ928301, 2, 3, ENSP000002259164EBI-2795524,EBI-477622 MINT-8012377 MINT-8012362 MINT-8012415 MINT-8012402 MINT-8012388 I2D: score=1 STRING: ENSP00000225916
    TADA2AO754782, 3, ENSP000002253964MINT-8012377 MINT-8012402 I2D: score=1 STRING: ENSP00000225396
    DNAJB11Q9UBS42, 3, ENSP000002650284MINT-8254331 I2D: score=2 STRING: ENSP00000265028
    CCDC101Q96ES72, ENSP000003161144MINT-8012377 MINT-8012362 MINT-8012388 STRING: ENSP00000316114
    ZBTB9Q96C003, ENSP000003785034I2D: score=1 STRING: ENSP00000378503
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006325chromatin organization TAS--
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    ZZZ3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZZZ3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ZZZ3 gene: 
    NM_015534.4  

    Unigene Cluster for ZZZ3:

    Zinc finger, ZZ-type containing 3
    Hs.480506  [show with all ESTs]
    Unigene Representative Sequence: AK074119
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000481346 ENST00000370801(uc001dhp.3 uc001dhq.3 uc009wbz.1 uc001dhr.3)
    ENST00000476275 ENST00000370798 ENST00000476195 ENST00000474746 ENST00000433749
    ENST00000414381 ENST00000463166 ENST00000469944 ENST00000458763
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZZZ3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZZZ3 (see all 70):
    hsa-miR-323-3p hsa-miR-520f hsa-miR-128 hsa-miR-3653 hsa-miR-342-3p hsa-miR-298 hsa-miR-556-3p hsa-miR-27a
    SwitchGear 3'UTR luciferase reporter plasmidZZZ3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZZZ3
    Predesigned siRNA for gene silencing in human, mouse, rat ZZZ3
    Clone
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    OriGene clones in human, mouse for ZZZ3 (see all 8)
    OriGene ORF clones in mouse, rat for ZZZ3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZZZ3 (NM_015534)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZZZ3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZZZ3
    Primer
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    OriGene qPCR primer pairs and template standards for ZZZ3
    OriGene qSTAR qPCR primer pairs in human, mouse for ZZZ3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZZZ3
      QuantiTect SYBR Green Assays in human, mouse, rat ZZZ3
      QuantiFast Probe-based Assays in human, mouse, rat ZZZ3

    Additional mRNA sequence: 

    AK001224.1 AK074119.1 AK310514.1 AL080063.1 BC035079.2 BC035397.1 BC035818.2 BX640658.1 
    BX640766.1 BX641001.1 BX641096.1 BX649026.1 

    15 DOTS entries:

    DT.313832  DT.115172  DT.100711180  DT.121440460  DT.40111562  DT.97816976  DT.91884234  DT.100777125 
    DT.115175  DT.121440500  DT.121440510  DT.121440540  DT.95191625  DT.99999261  DT.91924310 

    Selected AceView cDNA sequences (see all 191):

    AI159959 BI855941 AA910022 AK074119 BU688828 BM981117 AI651989 BQ631161 
    AA868735 CB105581 CA842460 BE879663 AA292701 BX109937 AI380030 CR616391 
    AA954945 NM_015534 BP872296 BQ006558 BM973558 AJ705133 BE047930 AW082688 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZZZ3 (see all 14)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c · 6d ^ 7a · 7b ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a ·
    SP1:                                                        -                                                           -     -                                 
    SP2:                    -     -     -     -                 -           -     -     -     -     -     -     -     -     -     -                                 
    SP3:                                                                                                                    -     -                                 
    SP4:                                                                                                                    -     -                                 
    SP5:                                                                                                                                                            

    ExUns: 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19
    SP1:                                          
    SP2:                                          
    SP3:                                          
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for ZZZ3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZZZ3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ZZZ3 Expression
    About this image

    ZZZ3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZZZ3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.480506
        Custom PCR Arrays for ZZZ3
    Primer
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    OriGene qPCR primer pairs and template standards for ZZZ3
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    QuantiFast Probe-based Assays in human, mouse, rat ZZZ3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZZZ3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ZZZ3 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zzz31 , 5 zinc finger, ZZ domain containing 31, 5 88(n)1
    87.38(a)1
      3 (77.16 cM)5
    1089461  NM_001080755.21  NP_001074224.11 
     1523954735 
    chicken
    (Gallus gallus)
    Aves ZZZ31 zinc finger, ZZ-type containing 3 81.61(n)
    81.42(a)
      424554  XM_004936675.1  XP_004936732.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZZZ36
    zinc finger, ZZ-type containing 3
    72(a)
    1 ↔ 1
    GL343194.1(4547559-4608410)
    African clawed frog
    (Xenopus laevis)
    Amphibia BG513566.12   -- 82.16(n)    BG513566.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570813272   -- 77.7(n)    57081327 
    fruit fly
    (Drosophila melanogaster)
    Insecta Atac11 ATAC component 1 48.9(n)
    46.7(a)
      33977  NM_135244.3  NP_609088.1 


    ENSEMBL Gene Tree for ZZZ3 (if available)
    TreeFam Gene Tree for ZZZ3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZZZ3 (see all 1939)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0357184
    A colorectal cancer sample4--see VAR_0357182 P S mis40--------
    rs2018726161,2
    --78029797(+) TTCCA-/GGAAAC 1 -- ds50010--------
    rs19625231,2
    C,F,A,H--78029905(-) TATTAT/ATGCTC 1 -- ds500114Minor allele frequency- A:0.29MN NS EA NA WA CSA 967
    rs1895838251,2
    --78029937(+) GGTCCA/GTGTTT 1 -- ds50010--------
    rs1813562831,2
    --78029985(+) ACACTA/GAGTAA 1 -- ds50010--------
    rs1858331411,2
    --78030000(+) CTTTAC/TCATTT 1 -- ds50010--------
    rs1890789311,2
    --78030054(+) CCTTAC/TTCTTC 1 -- ds50010--------
    rs1818161971,2
    --78030330(+) GCAGTA/GTAAAA 1 -- ut310--------
    rs1873122961,2
    --78030417(+) TTATGC/GATCTT 1 -- ut310--------
    rs1909074521,2
    --78030482(+) CAGTTG/TTCTTT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for ZZZ3 (78028101 - 78149104 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for ZZZ3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv830303CNV Loss17160897
    nsv870709CNV Loss21882294
    nsv1533CNV Loss18451855
    nsv871143CNV Gain21882294
    nsv470719CNV Gain18288195

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for ZZZ3:    
    About MalaCards
    breast and colorectal cancer    colorectal cancer


    ZZZ3 for disorders           About GeneDecksing


    Export disorders for ZZZ3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZZZ3 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with ZZZ3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. NF-Y affects histone acetylation and H2A.Z deposition in cell cycle promoters. (PubMed id 21304275)1, 3 Gatta R. and Mantovani R. (Epigenetics 2011)
    2. Host cell factor and an uncharacterized SANT domain protein are stable components of ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex in Drosophila. (PubMed id 16428443)1, 3 Guelman S....Workman J.L. (Mol. Cell. Biol. 2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. (PubMed id 23563607)1 Berndt S.I....Ingelsson E. (Nat. Genet. 2013)
    5. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PubMed id 24163370)1 Lu L....Zhang L. (J. Biol. Chem. 2013)
    6. Protein interactions of the transcription factor Hoxa1. (PubMed id 23088713)1 Lambert B....Rezsohazy R. (BMC Dev. Biol. 2012)
    7. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    8. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    9. Comparative proteomic analysis identifies a role for SUMO in protein quality control. (PubMed id 21693764)1 Tatham M.H....Hay R.T. (Sci Signal 2011)
    10. ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes. (PubMed id 20508642)1 Krebs A.R....Tora L. (EMBO Rep. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26009 HGNC: 24523 AceView: ZZZ3 Ensembl:ENSG00000036549 euGenes: HUgn26009
    ECgene: ZZZ3 H-InvDB: ZZZ3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ZZZ3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZZZ3 gene:
    Search GeneIP for patents involving ZZZ3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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