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ZWINT Gene

protein-coding   GIFtS: 59
GCID: GC10M058116

ZW10 Interacting Kinetochore Protein

(Previous name: ZW10 interactor)
  See ZWINT-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ZW10 Interacting Kinetochore Protein1 2     Human ZW10 Interacting Protein-12
ZW10 Interactor1 2     ZW10 Interactor, Kinetochore Protein2
HZwint-12     zwint-12
KNTC2AP2     Zwint-13
ZWINT12     ZW10-Interacting Protein 13

External Ids:    HGNC: 131951   Entrez Gene: 111302   Ensembl: ENSG000001229527   OMIM: 6091775   UniProtKB: O952293   

Export aliases for ZWINT gene to outside databases

Previous GC identifers: GC10M056945 GC10M057122 GC10M058009 GC10M057461 GC10M057787 GC10M052100


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ZWINT Gene:
This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known.
It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and
kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable
on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (provided by
RefSeq, Jul 2008)

GeneCards Summary for ZWINT Gene:
ZWINT (ZW10 interacting kinetochore protein) is a protein-coding gene. Diseases associated with ZWINT include roberts syndrome. GO annotations related to this gene include protein N-terminus binding.

UniProtKB/Swiss-Prot: ZWINT_HUMAN, O95229
Function: Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity.
Required to target ZW10 to the kinetochore at prometaphase

Gene Wiki entry for ZWINT Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for ZWINT
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZWINT promoter sequence
   Search Chromatin IP Primers for ZWINT

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZWINT


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q21-q22   Ensembl cytogenetic band:  10q21.1   HGNC cytogenetic band: 10q21-q22

ZWINT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZWINT gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M058116:  view genomic region     (about GC identifiers)

Start:
58,116,989 bp from pter      End:
58,121,036 bp from pter
Size:
4,048 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZWINT_HUMAN, O95229 (See protein sequence)
Recommended Name: ZW10 interactor  
Size: 277 amino acids; 31293 Da
Subunit: Interacts with ZW10 and MIS12. Interacts with the NDC80 subunit of the NDC80 complex specifically during
mitosis. Also interacts with CASC5, CETN3, DSN1 and PMF1
Secondary accessions: A6NNV6 Q0D2I3 Q9BWD0
Alternative splicing: 2 isoforms:  O95229-1   O95229-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZWINT: NX_O95229

Explore proteomics data for ZWINT at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys93, Lys100, Lys111, Lys116, Lys141, Lys162, Lys196
  • Modification sites at PhosphoSitePlus

  • See ZWINT Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001005413.1  NP_008988.2  NP_127490.1  

    ENSEMBL proteins: 
     ENSP00000363055   ENSP00000322850   ENSP00000473330   ENSP00000354921   ENSP00000378801  
    Reactome Protein details: O95229

    ZWINT Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: O95229


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZWINT_HUMAN, O95229
    Function: Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity.
    Required to target ZW10 to the kinetochore at prometaphase

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI15502821
    GO:0047485protein N-terminus binding IPI15485811
         
    Find genes that share ontologies with ZWINT           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZWINT
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZWINT

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZWINT:
    hsa-mir-149-5p (MIRT045620), hsa-mir-92a-1-5p (MIRT038916), hsa-mir-92a-3p (MIRT049834), hsa-mir-26b-5p (MIRT029953), hsa-mir-193b-3p (MIRT016569), hsa-mir-124-3p (MIRT022987)

    Block miRNA regulation of human, mouse, rat ZWINT using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ZWINT:
    hsa-miR-571
    SwitchGear 3'UTR luciferase reporter plasmidZWINT 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZWINT

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZWINT_HUMAN, O95229: Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late
    prophase to anaphase
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol4
    cytoskeleton1
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000776kinetochore IDA11682612
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA11682612
    GO:0005829cytosol TAS--

    Find genes that share ontologies with ZWINT           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZWINT About    
    See pathways by source

    SuperPathContained pathways About
    1Mitotic Metaphase and Anaphase
    Mitotic Anaphase0.94
    Mitotic Metaphase and Anaphase0.93
    Separation of Sister Chromatids0.94
    2Cell Cycle, Mitotic
    Cell Cycle, Mitotic0.90
    M Phase0.62
    Cell Cycle0.90
    3Mitotic Prometaphase
    Mitotic Prometaphase0.92
    Resolution of Sister Chromatid Cohesion0.92


    Find genes that share SuperPaths with ZWINT           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    3 Reactome Pathways for ZWINT
        Resolution of Sister Chromatid Cohesion
    Mitotic Prometaphase
    Separation of Sister Chromatids


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZWINT
    Interactions:

        GeneGlobe Interaction Network for ZWINT

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ZWINT (O952291, 2, 3 ENSP000003630554) via UniProtKB, MINT, STRING, and/or I2D (see all 98)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PHAXQ9H8142, 3, ENSP000002975404MINT-8277444 I2D: score=2 STRING: ENSP00000297540
    BECN1Q144571, 2, 3, ENSP000003552314EBI-1001132,EBI-949378 MINT-8304305 I2D: score=3 STRING: ENSP00000355231
    NDC80O147771, 3, ENSP000002615974EBI-1001132,EBI-715849 I2D: score=4 STRING: ENSP00000261597
    ZW10O432641, 3, ENSP000002001354EBI-1001132,EBI-1001217 I2D: score=2 STRING: ENSP00000200135
    DSN1Q9H4103, ENSP000003628504I2D: score=4 STRING: ENSP00000362850
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000070mitotic sister chromatid segregation IDA15485811
    GO:0000278mitotic cell cycle TAS--
    GO:0007049cell cycle NAS15504738
    GO:0007051spindle organization NAS15504738
    GO:0007093mitotic cell cycle checkpoint IDA15485811

    Find genes that share ontologies with ZWINT           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZWINT



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZWINT gene (4 alternative transcripts): 
    NM_001005413.1  NM_007057.3  NM_032997.2  NM_001005414.1  

    Unigene Cluster for ZWINT:

    ZW10 interactor, kinetochore protein
    Hs.591363  [show with all ESTs]
    Unigene Representative Sequence: NM_032997
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373944(uc001jjx.1) ENST00000494312(uc009xoy.1) ENST00000318387
    ENST00000489649 ENST00000460654 ENST00000361148 ENST00000478181 ENST00000467523
    ENST00000395405(uc001jjy.1 uc001jka.1)
    miRNA
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    hsa-miR-571
    SwitchGear 3'UTR luciferase reporter plasmidZWINT 3' UTR sequence
    Inhib. RNA
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat ZWINT
      QuantiFast Probe-based Assays in human, mouse, rat ZWINT

    Additional mRNA sequence: 

    AF067656.1 AK225509.1 AK293416.1 AK298148.1 BC000411.1 BC016357.2 BC020979.1 BC110399.1 

    11 DOTS entries:

    DT.214993  DT.100801012  DT.100801018  DT.101984029  DT.121299465  DT.121299457  DT.100029156  DT.92437637 
    DT.100801008  DT.100801017  DT.95171864 

    Selected AceView cDNA sequences (see all 231):

    AW118865 BM562031 CR595414 AA564001 AI888810 CR608012 BM699136 AI571035 
    BC020979 BC016357 CA416324 CA431155 AI250234 AA394261 AI026731 AA706968 
    BG505059 BX448627 AA356342 BX281545 BI859295 BX105168 BU155152 CR624675 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ZWINT    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5
    SP1:                                          
    SP2:                                          
    SP3:                                          


    ECgene alternative splicing isoforms for ZWINT

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZWINT expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATCCAAATG
    ZWINT Expression
    About this image


    ZWINT expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebellum
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    ZWINT Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZWINT Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.591363
        Custom PCR Arrays for ZWINT
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZWINT

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ZWINT gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zwint1 , 5 ZW10 interactor1, 5 72.06(n)1
    60.48(a)1
      10 (37.15 cM)5
    526961  NM_025635.31  NP_079911.11 
     726548455 
    lizard
    (Anolis carolinensis)
    Reptilia ZWINT6
    ZW10 interacting kinetochore protein
    32(a)
    1 ↔ 1
    2(69547239-69559169)


    ENSEMBL Gene Tree for ZWINT (if available)
    TreeFam Gene Tree for ZWINT (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZWINT (see all 184)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1898495831,2
    --58116701(+) CCACAC/TAAAGA 3 -- ds50010--------
    rs1473608521,2
    --58116773(+) AGTATA/GTAAGA 3 -- ds50010--------
    rs767464551,2
    C,F--58116821(+) CATAGT/CTGGAG 3 -- ds50013Minor allele frequency- C:0.04WA NA EA 358
    rs1819478811,2
    --58116826(+) TTGGAA/GATTTG 3 -- ds50010--------
    rs1860732181,2
    --58116958(+) ACCTAG/TGTGAA 3 -- ds50010--------
    rs2021887271,2
    C--58117040(+) TAAAC-/GATATGAT 3 -- ds50010--------
    rs1487909901,2
    --58117058(+) GACCAA/TATTAA 3 -- ds50010--------
    rs110053261,2
    C,F,A,H--58117124(+) TATGAA/GTCAAT 3 -- ds5001 ese320Minor allele frequency- G:0.23NS EA NA WA 2324
    rs1897483071,2
    --58117251(+) AATACA/GTGAGT 3 -- ut310--------
    rs1808001961,2
    --58117273(+) TAAAAA/GTAAGA 3 -- ut310--------

    HapMap Linkage Disequilibrium report for ZWINT (58116989 - 58121036 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ZWINT:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv727n71CNV Gain21882294
    nsv831883CNV Gain+Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZWINT
    DNA2.0 Custom Variant and Variant Library Synthesis for ZWINT

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609177    OMIM disorders: --

    1 disease for ZWINT:    
    About MalaCards
    roberts syndrome

    1 disease from the University of Copenhagen DISEASES database for ZWINT:
    Roberts syndrome

    Find genes that share disorders with ZWINT           About GenesLikeMe

    Genetic Association Database (GAD): ZWINT
    Human Genome Epidemiology (HuGE) Navigator: ZWINT (2 documents)

    Export disorders for ZWINT gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZWINT gene, integrated from 10 sources (see all 48):
    (articles sorted by number of sources associating them with ZWINT)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signaling. (PubMed id 15485811)1, 2, 9 Wang H.... Yao X. (J. Biol. Chem. 2004)
    2. HZwint-1, a novel human kinetochore component that interacts with HZW10. (PubMed id 10806105)1, 2, 9 Starr D.A....Goldberg M.L. (J. Cell Sci. 2000)
    3. Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control. (PubMed id 16732327)1, 2, 9 Lin Y.-T.... Lee W.-H. (Oncogene 2006)
    4. Recapitulation of the Roberts syndrome cellular phenotype by inhibition of INCENP, ZWINT-1 and ZW10 genes. (PubMed id 15094189)1, 2, 9 Musio A....Vezzoni P. (Gene 2004)
    5. Single nucleotide polymorphisms in chromosomal instability genes and risk and clinical outcome of breast cancer: a Swedish prospective case-control study. (PubMed id 19008095)1, 4 Brendle A....FAPrsti A. (Eur. J. Cancer 2009)
    6. Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease. (PubMed id 17373700)1, 4 Morgan A.R....Williams J. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2007)
    7. ZW10 links mitotic checkpoint signaling to the structural kinetochore. (PubMed id 15824131)1, 2 Kops G.J.P.L.... Cleveland D.W. (J. Cell Biol. 2005)
    8. A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. (PubMed id 15502821)1, 2 Obuse C....Yanagida M. (Nat. Cell Biol. 2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A. (PubMed id 11682612)1, 9 Van Hooser A.A....Brinkley B.R. (J. Cell. Sci. 2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 11130 HGNC: 13195 AceView: ZWINT Ensembl:ENSG00000122952 euGenes: HUgn11130
    ECgene: ZWINT H-InvDB: ZWINT

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZWINT Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZWINT gene:
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    GeneCards and IP:
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