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Aliases for ZUFSP Gene

Aliases for ZUFSP Gene

  • Zinc Finger With UFM1-Specific Peptidase Domain 2 3
  • C6orf113 3 4
  • Zinc Finger With UFM1-Specific Peptidase Domain Protein 3
  • Chromosome 6 Open Reading Frame 113 2
  • DJ412I7.3 3

External Ids for ZUFSP Gene

Previous HGNC Symbols for ZUFSP Gene

  • C6orf113

Previous GeneCards Identifiers for ZUFSP Gene

  • GC06M117064
  • GC06M116956
  • GC06M114536

Summaries for ZUFSP Gene

GeneCards Summary for ZUFSP Gene

ZUFSP (Zinc Finger With UFM1-Specific Peptidase Domain) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZUFSP Gene

Genomics for ZUFSP Gene

Regulatory Elements for ZUFSP Gene

Genomic Location for ZUFSP Gene

116,635,618 bp from pter
116,668,810 bp from pter
33,193 bases
Minus strand

Genomic View for ZUFSP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZUFSP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZUFSP Gene

Proteins for ZUFSP Gene

  • Protein details for ZUFSP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger with UFM1-specific peptidase domain protein
    Protein Accession:
    Secondary Accessions:
    • Q5TD92
    • Q6PJH7
    • Q96NV6

    Protein attributes for ZUFSP Gene

    578 amino acids
    Molecular mass:
    65959 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAI20499.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ZUFSP Gene


neXtProt entry for ZUFSP Gene

Proteomics data for ZUFSP Gene at MOPED

Post-translational modifications for ZUFSP Gene

  • Ubiquitination at Lys262, Lys276, Lys301, Lys356, Lys525, and Lys534
  • Modification sites at PhosphoSitePlus

Other Protein References for ZUFSP Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ZUFSP Gene

Domains for ZUFSP Gene

Gene Families for ZUFSP Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZUFSP Gene

Suggested Antigen Peptide Sequences for ZUFSP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q96AP4
  • Contains 3 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZUFSP: view

Function for ZUFSP Gene

Gene Ontology (GO) - Molecular Function for ZUFSP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZUFSP: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZUFSP

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZUFSP Gene

Localization for ZUFSP Gene

Subcellular locations from

Jensen Localization Image for ZUFSP Gene COMPARTMENTS Subcellular localization image for ZUFSP gene
Compartment Confidence
nucleus 3
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZUFSP Gene

Pathways for ZUFSP Gene

SuperPathways for ZUFSP Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZUFSP Gene


No data available for Pathways by source for ZUFSP Gene

Transcripts for ZUFSP Gene

Unigene Clusters for ZUFSP Gene

Zinc finger with UFM1-specific peptidase domain:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZUFSP

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZUFSP Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
SP2: -

Relevant External Links for ZUFSP Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZUFSP Gene

mRNA expression in normal human tissues for ZUFSP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for ZUFSP Gene

This gene is overexpressed in Fetal Brain (42.2), Platelet (17.1), and Brain (9.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZUFSP Gene

SOURCE GeneReport for Unigene cluster for ZUFSP Gene Hs.29857

genes like me logo Genes that share expressions with ZUFSP: view

Expression partners for ZUFSP Gene

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZUFSP Gene

Orthologs for ZUFSP Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZUFSP Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZUFSP 35
  • 90.08 (n)
  • 86.33 (a)
  • 86 (a)
(Canis familiaris)
Mammalia ZUFSP 35
  • 90.24 (n)
  • 88.04 (a)
  • 88 (a)
(Mus musculus)
Mammalia Zufsp 35
  • 86.56 (n)
  • 82.24 (a)
Zufsp 16
Zufsp 36
  • 82 (a)
(Pan troglodytes)
Mammalia ZUFSP 35
  • 99.6 (n)
  • 99.13 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Zufsp 35
  • 83.59 (n)
  • 81.28 (a)
(Monodelphis domestica)
Mammalia ZUFSP 36
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia ZUFSP 36
  • 70 (a)
(Gallus gallus)
Aves ZUFSP 35
  • 71.78 (n)
  • 72.18 (a)
  • 65 (a)
(Anolis carolinensis)
Reptilia ZUFSP 36
  • 71 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.3949 35
zufsp 35
  • 60.81 (n)
  • 58 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.19781 35
(Danio rerio)
Actinopterygii zufsp 35
  • 54.83 (n)
  • 47.98 (a)
zufsp 36
  • 43 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009608 35
  • 44.23 (n)
  • 38.36 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes mug105 35
  • 46.97 (n)
  • 34.85 (a)
Species with no ortholog for ZUFSP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZUFSP Gene

Gene Tree for ZUFSP (if available)
Gene Tree for ZUFSP (if available)

Paralogs for ZUFSP Gene

No data available for Paralogs for ZUFSP Gene

Variants for ZUFSP Gene

Sequence variations from dbSNP and Humsavar for ZUFSP Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs784137 -- 116,644,903(+) agGTG(A/G)AAAGA intron-variant
rs951833 -- 116,645,794(-) AACTT(C/T)GGAAA reference, missense
rs1084881 -- 116,639,524(+) attcg(C/T)ggttc intron-variant
rs1084882 -- 116,639,539(+) aaatc(C/T)gctgt intron-variant
rs1084883 -- 116,639,560(+) ctgct(A/G)ctgat intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZUFSP Gene

Variant ID Type Subtype PubMed ID
nsv523972 CNV Gain 19592680
nsv830783 CNV Gain 17160897
nsv5448 CNV Insertion 18451855

Relevant External Links for ZUFSP Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZUFSP Gene

Disorders for ZUFSP Gene

No disorders were found for ZUFSP Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZUFSP Gene

Publications for ZUFSP Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for ZUFSP Gene

Sources for ZUFSP Gene

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