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Aliases for ZUFSP Gene

Aliases for ZUFSP Gene

  • Zinc Finger With UFM1 Specific Peptidase Domain 2 3
  • C6orf113 3 4
  • Zinc Finger With UFM1-Specific Peptidase Domain 5
  • Chromosome 6 Open Reading Frame 113 2
  • DJ412I7.3 3

External Ids for ZUFSP Gene

Previous HGNC Symbols for ZUFSP Gene

  • C6orf113

Previous GeneCards Identifiers for ZUFSP Gene

  • GC06M117064
  • GC06M116956
  • GC06M114536

Summaries for ZUFSP Gene

GeneCards Summary for ZUFSP Gene

ZUFSP (Zinc Finger With UFM1 Specific Peptidase Domain) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZUFSP Gene

Genomics for ZUFSP Gene

Regulatory Elements for ZUFSP Gene

Promoters for ZUFSP Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZUFSP on UCSC Golden Path with GeneCards custom track

Genomic Location for ZUFSP Gene

116,635,618 bp from pter
116,668,810 bp from pter
33,193 bases
Minus strand

Genomic View for ZUFSP Gene

Genes around ZUFSP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZUFSP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZUFSP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZUFSP Gene

Proteins for ZUFSP Gene

  • Protein details for ZUFSP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger with UFM1-specific peptidase domain protein
    Protein Accession:
    Secondary Accessions:
    • Q5TD92
    • Q6PJH7
    • Q96NV6

    Protein attributes for ZUFSP Gene

    578 amino acids
    Molecular mass:
    65959 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAI20499.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ZUFSP Gene


neXtProt entry for ZUFSP Gene

Proteomics data for ZUFSP Gene at MOPED

Post-translational modifications for ZUFSP Gene

  • Ubiquitination at Lys 262, Lys 276, Lys 301, Lys 356, Lys 525, and Lys 534
  • Modification sites at PhosphoSitePlus

Other Protein References for ZUFSP Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZUFSP Gene

Domains & Families for ZUFSP Gene

Gene Families for ZUFSP Gene

Protein Domains for ZUFSP Gene

Suggested Antigen Peptide Sequences for ZUFSP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 3 C2H2-type zinc fingers.
  • Contains 3 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZUFSP: view

Function for ZUFSP Gene

Gene Ontology (GO) - Molecular Function for ZUFSP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ZUFSP: view
genes like me logo Genes that share phenotypes with ZUFSP: view

Animal Model Products

CRISPR Products

miRNA for ZUFSP Gene

miRTarBase miRNAs that target ZUFSP

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZUFSP Gene

Localization for ZUFSP Gene

Subcellular locations from

Jensen Localization Image for ZUFSP Gene COMPARTMENTS Subcellular localization image for ZUFSP gene
Compartment Confidence
nucleus 4
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZUFSP Gene

Pathways & Interactions for ZUFSP Gene

SuperPathways for ZUFSP Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZUFSP Gene


No data available for Pathways by source and SIGNOR curated interactions for ZUFSP Gene

Drugs & Compounds for ZUFSP Gene

No Compound Related Data Available

Transcripts for ZUFSP Gene

Unigene Clusters for ZUFSP Gene

Zinc finger with UFM1-specific peptidase domain:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZUFSP Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
SP2: -

Relevant External Links for ZUFSP Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZUFSP Gene

mRNA expression in normal human tissues for ZUFSP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZUFSP Gene

This gene is overexpressed in Fetal Brain (42.2), Platelet (17.1), and Brain (9.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZUFSP Gene

SOURCE GeneReport for Unigene cluster for ZUFSP Gene Hs.29857

genes like me logo Genes that share expression patterns with ZUFSP: view

Protein tissue co-expression partners for ZUFSP Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZUFSP Gene

Orthologs for ZUFSP Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZUFSP Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZUFSP 35
  • 90.08 (n)
  • 86.33 (a)
  • 86 (a)
(Canis familiaris)
Mammalia ZUFSP 35
  • 90.24 (n)
  • 88.04 (a)
  • 88 (a)
(Mus musculus)
Mammalia Zufsp 35
  • 86.56 (n)
  • 82.24 (a)
Zufsp 16
Zufsp 36
  • 82 (a)
(Pan troglodytes)
Mammalia ZUFSP 35
  • 99.6 (n)
  • 99.13 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Zufsp 35
  • 83.59 (n)
  • 81.28 (a)
(Monodelphis domestica)
Mammalia ZUFSP 36
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia ZUFSP 36
  • 70 (a)
(Gallus gallus)
Aves ZUFSP 35
  • 71.78 (n)
  • 72.18 (a)
  • 65 (a)
(Anolis carolinensis)
Reptilia ZUFSP 36
  • 71 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.3949 35
zufsp 35
  • 60.81 (n)
  • 58 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.19781 35
(Danio rerio)
Actinopterygii zufsp 35
  • 54.83 (n)
  • 47.98 (a)
zufsp 36
  • 43 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009608 35
  • 44.23 (n)
  • 38.36 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes mug105 35
  • 46.97 (n)
  • 34.85 (a)
Species with no ortholog for ZUFSP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZUFSP Gene

Gene Tree for ZUFSP (if available)
Gene Tree for ZUFSP (if available)

Paralogs for ZUFSP Gene

No data available for Paralogs for ZUFSP Gene

Variants for ZUFSP Gene

Sequence variations from dbSNP and Humsavar for ZUFSP Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs4946188 - 116,652,019(+) ATCGT(C/T)GTAAG reference, missense
rs784137 -- 116,644,903(+) agGTG(A/G)AAAGA intron-variant
rs951833 -- 116,645,794(-) AACTT(C/T)GGAAA reference, missense
rs1084881 -- 116,639,524(+) attcg(C/T)ggttc intron-variant
rs1084882 -- 116,639,539(+) aaatc(C/T)gctgt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZUFSP Gene

Variant ID Type Subtype PubMed ID
nsv523972 CNV Gain 19592680
nsv830783 CNV Gain 17160897
nsv5448 CNV Insertion 18451855

Variation tolerance for ZUFSP Gene

Residual Variation Intolerance Score: 41% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.94; 83.91% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZUFSP Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZUFSP Gene

Disorders for ZUFSP Gene

Relevant External Links for ZUFSP

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZUFSP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZUFSP Gene

Publications for ZUFSP Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Identifying protein partners of CLN8, an ER-resident protein involved in neuronal ceroid lipofuscinosis. (PMID: 23142642) Passantino R. … Guarneri P. (Biochim. Biophys. Acta 2013) 3
  5. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 3

Products for ZUFSP Gene

Sources for ZUFSP Gene

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