Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ZSWIM8 Gene

protein-coding GIFtS: 39
GCID: GC10P075549

Zinc Finger, SWIM-Type Containing 8

(Previous name: KIAA0913)
(Previous symbol: KIAA0913)

2 related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Zinc Finger, SWIM-Type Containing 8¹ ²
KIAA0913¹ ² ³
4832404P21Rik²
Zinc Finger SWIM Domain-Containing Protein 8²

External Ids:	HGNC: 23528¹	Entrez Gene: 23053²	Ensembl: ENSG00000214655⁷	UniProtKB: A7E2V4³

Export aliases for ZSWIM8 gene to outside databases

Previous GC identifer: GC10P075546

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ZSWIM8 Gene:

ZSWIM8 (zinc finger, SWIM-type containing 8) is a protein-coding gene. Diseases associated with ZSWIM8 include choroiditis, and alzheimer's disease. GO annotations related to this gene include zinc ion binding. An important paralog of this gene is ZSWIM4.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000010.10 NT_030059.13 NC_018921.2

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for ZSWIM8
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for ZSWIM8

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZSWIM8

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.2 Ensembl cytogenetic band: 10q22.2 HGNC cytogenetic band: 10q22.3

ZSWIM8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZSWIM8 gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10P075549: view genomic region (about GC identifiers)

Start:	75,545,340 bp from pter	End:	75,561,556 bp from pter
Size:	16,217 bases	Orientation:	plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZSWM8_HUMAN, A7E2V4 (See protein sequence)

Recommended Name: Zinc finger SWIM domain-containing protein 8

Size: 1837 amino acids; 197297 Da

Sequence caution: Sequence=AAI37250.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;

Sequence=AAI37251.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact; Sequence=BAA74936.2;

Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAA74936.2; Type=Miscellaneous

discrepancy; Note=Aberrant splicing; Sequence=BAB14664.1; Type=Erroneous initiation; Sequence=BAC03709.1;

Type=Miscellaneous discrepancy; Note=Probable cloning artifact;

Secondary accessions: B2RP37 O94987 Q17RS8 Q2TAB8 Q6P439 Q8IW81 Q8NB34 Q9H8F3

Alternative splicing: 5 isoforms: A7E2V4-1 A7E2V4-2 A7E2V4-3 A7E2V4-4 A7E2V4-5 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZSWIM8: NX_A7E2V4

Explore proteomics data for ZSWIM8 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_A7E2V4

ZSWIM8 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins (3 alternative transcripts):

NP_001229416.1 NP_001229417.1 NP_055852.2

ENSEMBL proteins:

ENSP00000474944 ENSP00000474043 ENSP00000474348 ENSP00000474748 ENSP00000387828

ENSP00000432423 ENSP00000474766 ENSP00000415612 ENSP00000474118 ENSP00000474677

ENSP00000381693

Human Recombinant Protein Products for ZSWIM8:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom MassSpec OriGene Custom Protein Services for ZSWIM8
	GenScript Custom Purified and Recombinant Proteins Services for ZSWIM8
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Cloud-Clone Corp.

ZSWIM8 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for ZSWIM8
	GenScript Custom Superior Antibodies Services for ZSWIM8
	Novus Biologicals ZSWIM8 Antibody
	Search for Antibodies for ZSWIM8 at Abcam
	Browse Antibodies at Cloud-Clone Corp.
	Search ThermoFisher Antibodies for ZSWIM8
	Search LSBio for Antibodies for ZSWIM8

Assay Products for ZSWIM8:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for ZSWIM8
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for ZSWIM8
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs at Cloud-Clone Corp. Browse CLIAs at Cloud-Clone Corp.

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

ZSWIM: Zinc fingers, SWIM-type

1 InterPro protein domain:

IPR007527 Znf_SWIM

Graphical View of Domain Structure for InterPro Entry A7E2V4

ProtoNet protein and cluster: A7E2V4

UniProtKB/Swiss-Prot: ZSWM8_HUMAN, A7E2V4

Similarity: Contains 1 SWIM-type zinc finger

ZSWIM8 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008270	zinc ion binding	IEA	--

ZSWIM8 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for ZSWIM8:

Increased HPV18 LCR reporter a

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for ZSWIM8

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZSWIM8

miRNA Products:
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZSWIM8
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ZSWIM8
		SwitchGear 3'UTR luciferase reporter plasmid: ZSWIM8 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for ZSWIM8
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZSWIM8
		Sirion Biotech Custom design and validation of potent shRNA sequences against ZSWIM8

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for ZSWIM8
			Sirion Biotech Customized adenovirus for overexpression of ZSWIM8 Customized adenovirus for potent knockdown of ZSWIM8

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene clones in human, mouse for ZSWIM8 (see all 5) OriGene ORF clones in mouse, rat for ZSWIM8 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for ZSWIM8
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZSWIM8
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSWIM8

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for ZSWIM8
		Search LifeMap BioReagents cell lines for ZSWIM8
		Sirion Biotech Customized stable knockdown cell line services for ZSWIM8 Customized inducible knockdown cell line services for ZSWIM8

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSWIM8

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ZSWIM8

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

5/11 Interacting proteins for ZSWIM8 (A7E2V4^{2, 3} ENSP00000381693⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 11)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ATXN1	P54253²^,³, ENSP00000244769⁴	MINT-2870293 MINT-2870274 I2D: score=3 STRING: ENSP00000244769
ATN1	P54259²^,³, ENSP00000349076⁴	MINT-2870255 I2D: score=3 STRING: ENSP00000349076
CSE1L	P55060³	I2D: score=1
GLI2	P10070³	I2D: score=1
HNRNPL	P14866³	I2D: score=1

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, IUPHAR, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZSWIM8 (ZSWM8)

Search CenterWatch for drugs/clinical trials and news about ZSWIM8 / ZSWM8

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ZSWIM8 gene (3 alternative transcripts):

NM_001242487.1 NM_001242488.1 NM_015037.3

Unigene Cluster for ZSWIM8:

Zinc finger, SWIM-type containing 8

Hs.65135 [show with all ESTs]

Unigene Representative Sequence: NM_015037

18/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23):

ENST00000604729 ENST00000603114 ENST00000446546 ENST00000604524 ENST00000605216

ENST00000433366 ENST00000451629 ENST00000492395(uc001jvh.3) ENST00000431225

ENST00000603187 ENST00000412198(uc009xrn.2) ENST00000604754 ENST00000425051

ENST00000489234 ENST00000487278 ENST00000603409 ENST00000604165 ENST00000603195

miRNA Products:
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZSWIM8
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ZSWIM8
		SwitchGear 3'UTR luciferase reporter plasmid: ZSWIM8 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for ZSWIM8
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZSWIM8
		Sirion Biotech Custom design and validation of potent shRNA sequences against ZSWIM8

Clone Products:		OriGene clones in human, mouse for ZSWIM8 (see all 5) OriGene ORF clones in mouse, rat for ZSWIM8 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for ZSWIM8
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZSWIM8
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSWIM8

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for ZSWIM8
		Search SABiosciences RT² qPCR Primer Assays in human, mouse, rat ZSWIM8
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZSWIM8
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZSWIM8

Additional mRNA sequence:

AB020720.2 AK023742.1 AK309136.1 AL133662.1 BC036835.1 BC040726.1 BC063694.1 BC111006.1

BC113914.1 BC117205.1 BC151206.1

15 DOTS entries:

DT.416369 DT.99992750 DT.92439537 DT.95276797 DT.75102940 DT.100688773 DT.121293079 DT.100786274

DT.86841533 DT.95276789 DT.100786272 DT.431157 DT.75109951 DT.92439530 DT.92439536

24/213 AceView cDNA sequences (see all 213):

BG473701 BF512501 BU733372 AA827335 BI757242 CA423127 BQ227817 AI240297

AW575812 AI200349 BC063694 BM712874 BE093457 AI753292 BC040726 AI383152

BI762688 BQ432258 BU685743 BE046486 BQ787218 AI589502 T31580 BE263631

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ZSWIM8 expression in normal human tissues (normalized intensities) ZSWIM8 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

ZSWIM8 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/3 selected tissues (see all 3) fully expand


Blood (Cardiovascular System) fully expand to see all 3 entries
umbilical cord reticulocytes

Heart (Cardiovascular System) fully expand to see all 2 entries
Atrioventricular Canal Cells Atrioventricular Canal
Outflow Tract

Umbilical Cord (Extraembryonic Tissues)
umbilical cord reticulocytes

See ZSWIM8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZSWIM8

SOURCE GeneReport for Unigene cluster: Hs.65135

SABiosciences Custom PCR Arrays for ZSWIM8

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for ZSWIM8
		Search SABiosciences RT² qPCR Primer Assays in human, mouse, rat ZSWIM8
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZSWIM8
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZSWIM8

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSWIM8

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for ZSWIM8 gene from 6/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Zswim8^{1 , 5}	RIKEN cDNA 2310021P13 gene⁵ zinc finger SWIM-type containing 8¹	91.23(n)¹ 97.44(a)¹		14 (11.53 cM)⁵ 268721¹ NM_001252082.1¹ NP_001239011.1¹ 20707552⁵
chicken (Gallus gallus)	Aves	KIAA0913¹	KIAA0913	74.32(n) 83.28(a)		423739 NM_001195600.1 NP_001182529.1
lizard (Anolis carolinensis)	Reptilia	ZSWIM8⁶	zinc finger, SWIM-type containing 8	82(a)	1 ↔ 1	GL343196.1(1364281-1414841)
African clawed frog (Xenopus laevis)	Amphibia	Xl.13157²	Xenopus laevis transcribed sequences	78(n)		CD326856.1
zebrafish (Danio rerio)	Actinopterygii	zgc:113421¹	zgc:113421	70.5(n) 77.86(a)		100148379 NM_001145707.1 NP_001139179.1
fruit fly (Drosophila melanogaster)	Insecta	CG34401¹	CG34401	55.1(n) 52.29(a)		50356 NM_144236.2 NP_652493.2

ENSEMBL Gene Tree for ZSWIM8 (if available)
TreeFam Gene Tree for ZSWIM8 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ZSWIM8 gene

ZSWIM4² ZSWIM5² ZSWIM6²

1 SIMAP similar gene for ZSWIM8 using alignment to 8 protein entries: ZSWM8_HUMAN (see all proteins):

KIAA0913

ZSWIM8 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs76092439^1,2	C,F	--	75543943(+)	`CCACTG/AGACTC`	3	--	us2k¹		1		EA	120
rs183914357^1,2		--	75544012(+)	`TCTCAA/GGTTAG`	3	--	us2k¹		0	--	--	--	--
rs187766648^1,2		--	75544022(+)	`GCTGCC/TTAGTT`	3	--	us2k¹		0	--	--	--	--
rs192445390^1,2		--	75544151(+)	`GTCTCA/GCTCTG`	3	--	us2k¹		0	--	--	--	--
rs34498422^1,2	C,F	--	75544307(+)	`AGAGAC/TGGGGT`	3	--	us2k¹		2		NA	4
rs11595202^1,2	H	--	75544399(+)	`ggcgtA/Gagcca`	3	--	us2k¹		0	--	--	--	--
rs184831836^1,2		--	75544499(+)	`CCAACA/TGAAAT`	3	--	us2k¹		0	--	--	--	--
rs189764550^1,2		--	75544586(+)	`ATACCA/GTGTTA`	3	--	us2k¹		0	--	--	--	--
rs79432392^1,2	F	--	75544649(+)	`ATTATG/AATAGT`	3	--	us2k¹		1		NA	120
rs151005515^1,2		--	75544800(+)	`GTAAAC/TGATCT`	3	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ZSWIM8 (75545340 - 75561556 bp)

Structural Variations
Database of Genomic Variants (DGV) variations for ZSWIM8: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZSWIM8

DNA2.0 Custom Variant and Variant Library Synthesis for ZSWIM8

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ZSWIM8 for disorders About GeneDecksing

2 diseases for ZSWIM8: About MalaCards

choroiditis alzheimer's disease

Export disorders for ZSWIM8 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ZSWIM8 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with ZSWIM8)

Utopia: connect your pdf to the dynamic
world of online information

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)^{1, 2} Nagase T....Ohara O. (1998)
Proteomic analysis of the NOS2 interactome in human ai rway epithelial cells. (PubMed id 23438482)¹ Foster M.W....Marshall H.E. (2013)
Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)¹ Tsai Y.C....Cristea I.M. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)¹ Lee K.A....Doedens J.R. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)² Olsen J.V....Mann M. (2010)
Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)¹ Bennett E.J....Harper J.W. (2010)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 23053	HGNC: 23528	AceView: KIAA0913	Ensembl:ENSG00000214655	euGenes: HUgn23053
ECgene: ZSWIM8	H-InvDB: ZSWIM8

(According to HUGE)
About This Section

HUGE: KIAA0913

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ZSWIM8	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ZSWIM8 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for ZSWIM8 gene:
Search GeneIP for patents involving ZSWIM8

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Protease Activity Assays and Reagents		Browse Recombinant/Natural Proteins
	Browse Stem Cell Products		Browse Tocris Biochemicals & Compounds
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for ZSWIM8
	Browse OriGene qPCR primer pairs and template standards		Browse OriGene Protein Over-expression Lysates
	OriGene Custom Mass Spec		OriGene clones in human, mouse for ZSWIM8
	OriGene qSTAR qPCR primer pairs in human, mouse for ZSWIM8		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
	OriGene ORF clones in mouse, rat for ZSWIM8		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for ZSWIM8		OriGene Custom Protein Services for ZSWIM8

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZSWIM8
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZSWIM8
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZSWIM8
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZSWIM8
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZSWIM8
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZSWIM8

	GenScript Custom Purified and Recombinant Proteins Services for ZSWIM8		GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for ZSWIM8
	GenScript Custom Assay Services for ZSWIM8		GenScript Custom Superior Antibodies Services for ZSWIM8
	GenScript Custom overexpressing Cell Line Services for ZSWIM8		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Search Regulatory tfbs for ZSWIM8
	Search Chromatin IP Primers for ZSWIM8
	Search RT² qPCR Primer Assays in human, mouse, rat ZSWIM8
	Search GNC Networks for ZSWIM8
	SABiosciences Custom PCR Arrays for ZSWIM8

Search Tocris compounds for ZSWIM8 (ZSWM8)

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological Cell Lysates
	Browse Sino Biological cDNA Clones
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	ZSWIM8 antibodies

	Search for Antibodies for ZSWIM8 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for ZSWIM8
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Browse Proteins at Cloud-Clone Corp.
	Browse Antibodies at Cloud-Clone Corp.
	Browse ELISAs at Cloud-Clone Corp.
	Browse CLIAs at Cloud-Clone Corp.

Search LifeMap BioReagents cell lines for ZSWIM8

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSWIM8

	SwitchGear 3'UTR luciferase reporter plasmids for ZSWIM8
	Browse SwitchGear Promoter luciferase reporter plasmids for ZSWIM8

Search ThermoFisher Antibodies for ZSWIM8

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSWIM8

	inGenious Targeting Laboratory - Custom generated mouse model solutions for ZSWIM8
	inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZSWIM8

Customized:

	stable knockdown cell line services for ZSWIM8
	inducible knockdown cell line services for ZSWIM8
	design and validation of potent shRNA sequences against ZSWIM8
	adenovirus for potent knockdown of ZSWIM8
	stable overexpressing cell line services
	inducible overexpressing cell line services
	adenovirus for overexpression of ZSWIM8

Search LSBio for Antibodies for ZSWIM8

GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013

View Random Gene

Category			TGFB1 (GIFtS: 73) transforming growth factor, beta 1
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes ZSWIM8 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

ZSWIM8 Gene

Zinc Finger, SWIM-Type Containing 8

Aliases
for ZSWIM8 gene

Summaries
for ZSWIM8 gene

Genomic Views
for ZSWIM8 gene

Proteins
for ZSWIM8 gene

Protein Domains /
Families
for ZSWIM8 gene

Function
for ZSWIM8 gene

Pathways & Interactions
for ZSWIM8 gene

Drugs & Compounds
for ZSWIM8 gene

Transcripts
for ZSWIM8 gene

Expression
for ZSWIM8 gene

Orthologs
for ZSWIM8 gene

Paralogs
for ZSWIM8 gene

Genomic Variants
for ZSWIM8 gene

Disorders / Diseases
for ZSWIM8 gene

Publications
for ZSWIM8 gene

External Searches for ZSWIM8 gene

Genome Databases showing ZSWIM8 gene

Other Databases showing ZSWIM8 gene

Specialized Databases showing ZSWIM8 gene

Intellectual Property
for ZSWIM8 gene

Products
for ZSWIM8 gene

View Random Gene

Advanced Search

Export list of displayed genes

ZSWIM8 Gene

Zinc Finger, SWIM-Type Containing 8

Aliasesfor ZSWIM8 gene

Summariesfor ZSWIM8 gene

Genomic Viewsfor ZSWIM8 gene

Proteinsfor ZSWIM8 gene

Protein Domains /Familiesfor ZSWIM8 gene

Functionfor ZSWIM8 gene

Pathways & Interactionsfor ZSWIM8 gene

Drugs & Compoundsfor ZSWIM8 gene

Transcriptsfor ZSWIM8 gene

Expression for ZSWIM8 gene

Orthologsfor ZSWIM8 gene

Paralogsfor ZSWIM8 gene

Genomic Variantsfor ZSWIM8 gene

Disorders / Diseasesfor ZSWIM8 gene

Publicationsfor ZSWIM8 gene

External Searches for ZSWIM8 gene

Genome Databases showing ZSWIM8 gene

Other Databases showing ZSWIM8 gene

Specialized Databases showing ZSWIM8 gene

Intellectual Propertyfor ZSWIM8 gene

Productsfor ZSWIM8 gene

View Random Gene

Aliases
for ZSWIM8 gene

Summaries
for ZSWIM8 gene

Genomic Views
for ZSWIM8 gene

Proteins
for ZSWIM8 gene

Protein Domains /
Families
for ZSWIM8 gene

Function
for ZSWIM8 gene

Pathways & Interactions
for ZSWIM8 gene

Drugs & Compounds
for ZSWIM8 gene

Transcripts
for ZSWIM8 gene

Expression
for ZSWIM8 gene

Orthologs
for ZSWIM8 gene

Paralogs
for ZSWIM8 gene

Genomic Variants
for ZSWIM8 gene

Disorders / Diseases
for ZSWIM8 gene

Publications
for ZSWIM8 gene

Intellectual Property
for ZSWIM8 gene

Products
for ZSWIM8 gene