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Aliases for ZSWIM8 Gene

Aliases for ZSWIM8 Gene

  • Zinc Finger, SWIM-Type Containing 8 2 3
  • KIAA0913 2 3 4
  • Zinc Finger SWIM Domain-Containing Protein 8 3
  • 4832404P21Rik 3

External Ids for ZSWIM8 Gene

Previous HGNC Symbols for ZSWIM8 Gene

  • KIAA0913

Previous GeneCards Identifiers for ZSWIM8 Gene

  • GC10P075546
  • GC10P075549
  • GC10P075555

Summaries for ZSWIM8 Gene

GeneCards Summary for ZSWIM8 Gene

ZSWIM8 (Zinc Finger, SWIM-Type Containing 8) is a Protein Coding gene. An important paralog of this gene is ZSWIM6.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSWIM8 Gene

Genomics for ZSWIM8 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZSWIM8 Gene

Start:
73,785,576 bp from pter
End:
73,801,798 bp from pter
Size:
16,223 bases
Orientation:
Plus strand

Genomic View for ZSWIM8 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZSWIM8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSWIM8 Gene

No data available for Regulatory Elements for ZSWIM8 Gene

Proteins for ZSWIM8 Gene

  • Protein details for ZSWIM8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A7E2V4-ZSWM8_HUMAN
    Recommended name:
    Zinc finger SWIM domain-containing protein 8
    Protein Accession:
    A7E2V4
    Secondary Accessions:
    • B2RP37
    • O94987
    • Q17RS8
    • Q2TAB8
    • Q6P439
    • Q8IW81
    • Q8NB34
    • Q9H8F3

    Protein attributes for ZSWIM8 Gene

    Size:
    1837 amino acids
    Molecular mass:
    197297 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI37250.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305}; Sequence=AAI37251.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305}; Sequence=BAA74936.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAA74936.2; Type=Miscellaneous discrepancy; Note=Aberrant splicing.; Evidence={ECO:0000305}; Sequence=BAB14664.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAC03709.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZSWIM8 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSWIM8 Gene

Proteomics data for ZSWIM8 Gene at MOPED

Post-translational modifications for ZSWIM8 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZSWIM8 Gene

Domains for ZSWIM8 Gene

Gene Families for ZSWIM8 Gene

HGNC:
  • ZSWIM :Zinc fingers, SWIM-type

Protein Domains for ZSWIM8 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

A7E2V4

UniProtKB/Swiss-Prot:

ZSWM8_HUMAN :
  • A7E2V4
Similarity:
  • Contains 1 SWIM-type zinc finger.
genes like me logo Genes that share domains with ZSWIM8: view

No data available for Suggested Antigen Peptide Sequences for ZSWIM8 Gene

Function for ZSWIM8 Gene

Gene Ontology (GO) - Molecular Function for ZSWIM8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZSWIM8: view

Phenotypes for ZSWIM8 Gene

GenomeRNAi human phenotypes for ZSWIM8:
genes like me logo Genes that share phenotypes with ZSWIM8: view

Animal Model Products

CRISPR Products

miRNA for ZSWIM8 Gene

miRTarBase miRNAs that target ZSWIM8

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZSWIM8

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZSWIM8 Gene

Localization for ZSWIM8 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ZSWIM8 Gene

Pathways for ZSWIM8 Gene

SuperPathways for ZSWIM8 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZSWIM8 Gene

None

No data available for Pathways by source for ZSWIM8 Gene

Transcripts for ZSWIM8 Gene

Unigene Clusters for ZSWIM8 Gene

Zinc finger, SWIM-type containing 8:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZSWIM8

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSWIM8 Gene

No ASD Table

Relevant External Links for ZSWIM8 Gene

GeneLoc Exon Structure for
ZSWIM8
ECgene alternative splicing isoforms for
ZSWIM8

Expression for ZSWIM8 Gene

mRNA expression in normal human tissues for ZSWIM8 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for ZSWIM8 Gene

This gene is overexpressed in Brain (53.2).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for ZSWIM8 Gene

SOURCE GeneReport for Unigene cluster for ZSWIM8 Gene Hs.65135

genes like me logo Genes that share expressions with ZSWIM8: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for ZSWIM8 Gene

Orthologs for ZSWIM8 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZSWIM8 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZSWIM8 35
  • 93.38 (n)
  • 98.58 (a)
ZSWIM8 36
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZSWIM8 35
  • 94.18 (n)
  • 98.75 (a)
ZSWIM8 36
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zswim8 35
  • 91.24 (n)
  • 97.49 (a)
Zswim8 16
Zswim8 36
  • 97 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZSWIM8 35
  • 99.75 (n)
  • 99.95 (a)
KIAA0913 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zswim8 35
  • 90.81 (n)
  • 97.15 (a)
oppossum
(Monodelphis domestica)
Mammalia ZSWIM8 36
  • 91 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZSWIM8 36
  • 73 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA0913 35
  • 73.81 (n)
  • 82.45 (a)
KIAA0913 36
  • 80 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZSWIM8 36
  • 82 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia zswim8 35
  • 70.94 (n)
  • 80.84 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.13157 35
zebrafish
(Danio rerio)
Actinopterygii zswim8 35
  • 70.27 (n)
  • 77.52 (a)
zswim8 36
  • 72 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG34401 36
  • 40 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 43 (a)
OneToOne
Species with no ortholog for ZSWIM8:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZSWIM8 Gene

ENSEMBL:
Gene Tree for ZSWIM8 (if available)
TreeFam:
Gene Tree for ZSWIM8 (if available)

Paralogs for ZSWIM8 Gene

Paralogs for ZSWIM8 Gene

Selected SIMAP similar genes for ZSWIM8 Gene using alignment to 10 proteins:

genes like me logo Genes that share paralogs with ZSWIM8: view

Variants for ZSWIM8 Gene

Sequence variations from dbSNP and Humsavar for ZSWIM8 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs1273138 -- 73,794,921(+) catct(C/T)tactt intron-variant
rs2292307 -- 73,790,158(+) GACTG(A/C)CTGTC intron-variant
rs3036236 -- 73,786,960(+) TTTTT(-/T)GAGAC intron-variant
rs3740290 -- 73,795,786(+) AACCC(C/T)GTCTC intron-variant
rs3740291 -- 73,795,920(+) ttcac(A/G)ccact intron-variant

Relevant External Links for ZSWIM8 Gene

HapMap Linkage Disequilibrium report
ZSWIM8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZSWIM8 Gene

Disorders for ZSWIM8 Gene

No disorders were found for ZSWIM8 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZSWIM8 Gene

Publications for ZSWIM8 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10048485) Nagase T. … Ohara O. (DNA Res. 1998) 3 4
  3. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3
  4. Expressed sequence tag analysis of human RPE/choroid for the NEIBank project: over 6000 non-redundant transcripts, novel genes and splice variants. (PMID: 12107410) Wistow G. … Peterson K. (Mol. Vis. 2002) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZSWIM8 Gene

Sources for ZSWIM8 Gene

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