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ZSWIM8 Gene

protein-coding   GIFtS: 39
GCID: GC10P075555

Zinc Finger, SWIM-Type Containing 8

(Previous name: KIAA0913)
(Previous symbol: KIAA0913)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger, SWIM-Type Containing 81 2
KIAA09131 2 3
4832404P21Rik2
Zinc Finger SWIM Domain-Containing Protein 82

External Ids:    HGNC: 235281   Entrez Gene: 230532   Ensembl: ENSG000002146557   UniProtKB: A7E2V43   

Export aliases for ZSWIM8 gene to outside databases

Previous GC identifers: GC10P075546 GC10P075549


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZSWIM8 Gene:
ZSWIM8 (zinc finger, SWIM-type containing 8) is a protein-coding gene. Diseases associated with ZSWIM8 include choroiditis, and ataxia. An important paralog of this gene is ZSWIM4.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NT_030059.14  NC_018921.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for ZSWIM8
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ZSWIM8

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZSWIM8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.2   Ensembl cytogenetic band:  10q22.2   HGNC cytogenetic band: 10q22.3

ZSWIM8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZSWIM8 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P075555:  view genomic region     (about GC identifiers)

Start:
75,545,340 bp from pter      End:
75,561,556 bp from pter
Size:
16,217 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZSWM8_HUMAN, A7E2V4 (See protein sequence)
Recommended Name: Zinc finger SWIM domain-containing protein 8  
Size: 1837 amino acids; 197297 Da
Sequence caution: Sequence=AAI37250.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;
Sequence=AAI37251.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact; Sequence=BAA74936.2;
Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAA74936.2; Type=Miscellaneous
discrepancy; Note=Aberrant splicing; Sequence=BAB14664.1; Type=Erroneous initiation; Sequence=BAC03709.1;
Type=Miscellaneous discrepancy; Note=Probable cloning artifact;
Secondary accessions: B2RP37 O94987 Q17RS8 Q2TAB8 Q6P439 Q8IW81 Q8NB34 Q9H8F3
Alternative splicing: 5 isoforms:  A7E2V4-1   A7E2V4-2   A7E2V4-3   A7E2V4-4   A7E2V4-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZSWIM8: NX_A7E2V4

Explore proteomics data for ZSWIM8 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZSWIM8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001229416.1  NP_001229417.1  NP_055852.2  

    ENSEMBL proteins: 
     ENSP00000474944   ENSP00000474043   ENSP00000474348   ENSP00000474748   ENSP00000387828  
     ENSP00000432423   ENSP00000474766   ENSP00000415612   ENSP00000474118   ENSP00000474677  
     ENSP00000381693  

    ZSWIM8 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Custom Protein Services for ZSWIM8
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

    ZSWIM8 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZSWIM8
    Novus Biologicals ZSWIM8 Antibody
    Search for Antibodies for ZSWIM8 at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    Search ThermoFisher Antibodies for ZSWIM8
    Search LSBio for Antibodies for ZSWIM8

    ZSWIM8 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZSWIM8
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZSWIM: Zinc fingers, SWIM-type

    1 InterPro protein domain:
     IPR007527 Znf_SWIM

    Graphical View of Domain Structure for InterPro Entry A7E2V4

    ProtoNet protein and cluster: A7E2V4

    UniProtKB/Swiss-Prot: ZSWM8_HUMAN, A7E2V4
    Similarity: Contains 1 SWIM-type zinc finger


    ZSWIM8 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
         
    ZSWIM8 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ZSWIM8:
     Increased HPV18 LCR reporter a 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZSWIM8
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZSWIM8

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZSWIM8
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZSWIM8

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZSWIM8:
    hsa-mir-149-5p (MIRT045440), hsa-mir-484 (MIRT042386)

    Block miRNA regulation of human, mouse, rat ZSWIM8 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate ZSWIM8
    SwitchGear 3'UTR luciferase reporter plasmidZSWIM8 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZSWIM8
    Predesigned siRNA for gene silencing in human, mouse, rat ZSWIM8

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for ZSWIM8

    Clone
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    OriGene clones in human, mouse for ZSWIM8 (see all 5)
    OriGene ORF clones in mouse, rat for ZSWIM8
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for ZSWIM8
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZSWIM8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSWIM8

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for ZSWIM8 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSWIM8


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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      --

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZSWIM8
    Interactions:

        Search GeneGlobe Interaction Network for ZSWIM8

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for ZSWIM8 (A7E2V42, 3 ENSP000003816934) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN1P542532, 3, ENSP000002447694MINT-2870293 MINT-2870274 I2D: score=3 STRING: ENSP00000244769
    ATN1P542592, 3, ENSP000003490764MINT-2870255 I2D: score=3 STRING: ENSP00000349076
    CSE1LP550603I2D: score=1 
    GLI2P100703I2D: score=1 
    HNRNPLP148663I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZSWIM8 (ZSWM8)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ZSWIM8 gene (3 alternative transcripts): 
    NM_001242487.1  NM_001242488.1  NM_015037.3  

    Unigene Cluster for ZSWIM8:

    Zinc finger, SWIM-type containing 8
    Hs.65135  [show with all ESTs]
    Unigene Representative Sequence: NM_015037
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23):
    ENST00000604729 ENST00000603114 ENST00000446546 ENST00000604524 ENST00000605216
    ENST00000433366 ENST00000451629 ENST00000492395(uc001jvh.3) ENST00000431225
    ENST00000603187 ENST00000412198(uc009xrn.2) ENST00000604754 ENST00000425051
    ENST00000489234 ENST00000487278 ENST00000603409 ENST00000604165 ENST00000603195

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZSWIM8 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate ZSWIM8
    SwitchGear 3'UTR luciferase reporter plasmidZSWIM8 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZSWIM8
    Predesigned siRNA for gene silencing in human, mouse, rat ZSWIM8
    Clone
    Products:
         
    OriGene clones in human, mouse for ZSWIM8 (see all 5)
    OriGene ORF clones in mouse, rat for ZSWIM8
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for ZSWIM8
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZSWIM8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSWIM8
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ZSWIM8
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat ZSWIM8
      QuantiTect SYBR Green Assays in human, mouse, rat ZSWIM8
      QuantiFast Probe-based Assays in human, mouse, rat ZSWIM8

    Additional mRNA sequence: 

    AB020720.2 AK023742.1 AK309136.1 AL133662.1 BC036835.1 BC040726.1 BC063694.1 BC111006.1 
    BC113914.1 BC117205.1 BC151206.1 

    15 DOTS entries:

    DT.416369  DT.99992750  DT.92439537  DT.95276797  DT.75102940  DT.100688773  DT.121293079  DT.100786274 
    DT.86841533  DT.95276789  DT.100786272  DT.431157  DT.75109951  DT.92439530  DT.92439536 

    Selected AceView cDNA sequences (see all 213):

    BE778038 BQ640275 BQ227817 BQ676406 BE833282 CD742672 BU786041 BQ786940 
    AI702493 BI757242 AI589502 AI383152 BU621409 BF529727 BQ575546 AI991978 
    BE046486 AL133662 BU743235 AI992285 CR610954 AA443585 BE385083 BU685743 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZSWIM8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ZSWIM8 Expression
    About this image


    ZSWIM8 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Heart (Cardiovascular System)    fully expand to see all 2 entries
             Atrioventricular Canal Cells Atrioventricular Canal
             Outflow Tract
    ZSWIM8 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZSWIM8 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.65135
        Custom PCR Arrays for ZSWIM8
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ZSWIM8
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSWIM8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ZSWIM8 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zswim81 , 5 RIKEN cDNA 2310021P13 gene5
    zinc finger SWIM-type containing 81
    91.24(n)1
    97.49(a)1
      14 (11.53 cM)5
    2687211  NM_001252082.11  NP_001239011.11 
     207075525 
    chicken
    (Gallus gallus)
    Aves KIAA09131 KIAA0913 73.81(n)
    82.45(a)
      423739  NM_001195600.1  NP_001182529.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZSWIM86
    zinc finger, SWIM-type containing 8
    82(a)
    1 ↔ 1
    GL343196.1(1364281-1414841)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.131572 Xenopus laevis transcribed sequences 78(n)    CD326856.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zswim81 zinc finger, SWIM-type containing 8 70.27(n)
    77.52(a)
      100148379  NM_001145707.1  NP_001139179.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG344016
    --
    40(a)
    1 ↔ 1
    X(18757983-18778108)


    ENSEMBL Gene Tree for ZSWIM8 (if available)
    TreeFam Gene Tree for ZSWIM8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZSWIM8 gene
    ZSWIM42  ZSWIM52  ZSWIM62  
    1 SIMAP similar gene for ZSWIM8 using alignment to 10 protein entries:     ZSWM8_HUMAN (see all proteins):
    KIAA0913

    ZSWIM8 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZSWIM8 (see all 262)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs760924391,2
    C,F--75543943(+) CCACTG/AGACTC 3 -- us2k11Minor allele frequency- A:0.05EA 120
    rs1839143571,2
    --75544012(+) TCTCAA/GGTTAG 3 -- us2k10--------
    rs1877666481,2
    --75544022(+) GCTGCC/TTAGTT 3 -- us2k10--------
    rs1924453901,2
    --75544151(+) GTCTCA/GCTCTG 3 -- us2k10--------
    rs344984221,2
    C,F--75544307(+) AGAGAC/TGGGGT 3 -- us2k12Minor allele frequency- T:0.50NA 4
    rs115952021,2
    H--75544399(+) ggcgtA/Gagcca 3 -- us2k10--------
    rs1848318361,2
    --75544499(+) CCAACA/TGAAAT 3 -- us2k10--------
    rs1897645501,2
    --75544586(+) ATACCA/GTGTTA 3 -- us2k10--------
    rs794323921,2
    F--75544649(+) ATTATG/AATAGT 3 -- us2k11Minor allele frequency- A:0.01NA 120
    rs1510055151,2
    --75544800(+) GTAAAC/TGATCT 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZSWIM8 (75545340 - 75561556 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ZSWIM8: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZSWIM8
    DNA2.0 Custom Variant and Variant Library Synthesis for ZSWIM8

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    4 diseases for ZSWIM8:    
    About MalaCards
    choroiditis    ataxia    alzheimer's disease    malaria


    ZSWIM8 for disorders           About GeneDecksing


    Export disorders for ZSWIM8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZSWIM8 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with ZSWIM8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2 Nagase T.... Ohara O. (DNA Res. 1998)
    3. Proteomic analysis of the NOS2 interactome in human airway epithelial cells. (PubMed id 23438482)1 Foster M.W....Marshall H.E. (Nitric Oxide 2013)
    4. Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    6. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (J. Biol. Chem. 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    9. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    10. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23053 HGNC: 23528 AceView: KIAA0913 Ensembl:ENSG00000214655 euGenes: HUgn23053
    ECgene: ZSWIM8 H-InvDB: ZSWIM8

    (According to HUGE)
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    HUGE: KIAA0913

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZSWIM8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZSWIM8 gene:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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