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ZSWIM8 Gene

protein-coding GIFtS: 39
GCID: GC10P075555

Zinc Finger, SWIM-Type Containing 8

(Previous name: KIAA0913)
(Previous symbol: KIAA0913)

See related diseases
at

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
Zinc Finger, SWIM-Type Containing 8¹ ²
KIAA0913¹ ² ³
4832404P21Rik²
Zinc Finger SWIM Domain-Containing Protein 8²

External Ids:	HGNC: 23528¹	Entrez Gene: 23053²	Ensembl: ENSG00000214655⁷	UniProtKB: A7E2V4³

Export aliases for ZSWIM8 gene to outside databases

Previous GC identifers: GC10P075546 GC10P075549

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZSWIM8 Gene:

ZSWIM8 (zinc finger, SWIM-type containing 8) is a protein-coding gene. Diseases associated with ZSWIM8 include choroiditis, and ataxia. An important paralog of this gene is ZSWIM4.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000010.11 NT_030059.14 NC_018921.2

Regulatory elements:

Search for regulatory transcription factor binding sites for ZSWIM8
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search Chromatin IP Primers for ZSWIM8

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZSWIM8

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.2 Ensembl cytogenetic band: 10q22.2 HGNC cytogenetic band: 10q22.3

ZSWIM8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZSWIM8 gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10P075555: view genomic region (about GC identifiers)

Start:	75,545,340 bp from pter	End:	75,561,556 bp from pter
Size:	16,217 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ZSWM8_HUMAN, A7E2V4 (See protein sequence)

Recommended Name: Zinc finger SWIM domain-containing protein 8

Size: 1837 amino acids; 197297 Da

Sequence caution: Sequence=AAI37250.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;

Sequence=AAI37251.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact; Sequence=BAA74936.2;

Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAA74936.2; Type=Miscellaneous

discrepancy; Note=Aberrant splicing; Sequence=BAB14664.1; Type=Erroneous initiation; Sequence=BAC03709.1;

Type=Miscellaneous discrepancy; Note=Probable cloning artifact;

Secondary accessions: B2RP37 O94987 Q17RS8 Q2TAB8 Q6P439 Q8IW81 Q8NB34 Q9H8F3

Alternative splicing: 5 isoforms: A7E2V4-1 A7E2V4-2 A7E2V4-3 A7E2V4-4 A7E2V4-5 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZSWIM8: NX_A7E2V4

Explore proteomics data for ZSWIM8 at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See ZSWIM8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (3 alternative transcripts):

NP_001229416.1 NP_001229417.1 NP_055852.2

ENSEMBL proteins:

ENSP00000474944 ENSP00000474043 ENSP00000474348 ENSP00000474748 ENSP00000387828

ENSP00000432423 ENSP00000474766 ENSP00000415612 ENSP00000474118 ENSP00000474677

ENSP00000381693

ZSWIM8 Human Recombinant Protein Products:

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	Browse ProSpec Recombinant Proteins
	Browse Proteins at Cloud-Clone Corp.

ZSWIM8 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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	Novus Biologicals ZSWIM8 Antibody
	Search for Antibodies for ZSWIM8 at Abcam
	Browse Antibodies at Cloud-Clone Corp.
	Search ThermoFisher Antibodies for ZSWIM8
	Search LSBio for Antibodies for ZSWIM8

ZSWIM8 Assay Products:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for ZSWIM8
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for ZSWIM8
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs at Cloud-Clone Corp. Browse CLIAs at Cloud-Clone Corp.

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:

ZSWIM: Zinc fingers, SWIM-type

1 InterPro protein domain:

IPR007527 Znf_SWIM

Graphical View of Domain Structure for InterPro Entry A7E2V4

ProtoNet protein and cluster: A7E2V4

UniProtKB/Swiss-Prot: ZSWM8_HUMAN, A7E2V4

Similarity: Contains 1 SWIM-type zinc finger

ZSWIM8 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Gene Ontology (GO): 1 molecular function term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008270	zinc ion binding	IEA	--

ZSWIM8 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for ZSWIM8:

Increased HPV18 LCR reporter a

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZSWIM8

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZSWIM8

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZSWIM8

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZSWIM8

miRNA Products:		miRTarBase miRNAs that target ZSWIM8: hsa-mir-149-5p (MIRT045440), hsa-mir-484 (MIRT042386)

		Block miRNA regulation of human, mouse, rat ZSWIM8 using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate ZSWIM8
		SwitchGear 3'UTR luciferase reporter plasmid: ZSWIM8 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for ZSWIM8
		Predesigned siRNA for gene silencing in human, mouse, rat ZSWIM8

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for ZSWIM8

Clone Products:		OriGene clones in human, mouse for ZSWIM8 (see all 5) OriGene ORF clones in mouse, rat for ZSWIM8 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for ZSWIM8
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZSWIM8
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSWIM8

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for ZSWIM8
		Browse ESI BIO Cell Lines and PureStem Progenitors for ZSWIM8

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSWIM8

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for ZSWIM8
Interactions:

Search GeneGlobe Interaction Network for ZSWIM8

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

Selected Interacting proteins for ZSWIM8 (A7E2V4^{2, 3} ENSP00000381693⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 11)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ATXN1	P54253²^,³, ENSP00000244769⁴	MINT-2870293 MINT-2870274 I2D: score=3 STRING: ENSP00000244769
ATN1	P54259²^,³, ENSP00000349076⁴	MINT-2870255 I2D: score=3 STRING: ENSP00000349076
CSE1L	P55060³	I2D: score=1
GLI2	P10070³	I2D: score=1
HNRNPL	P14866³	I2D: score=1

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for ZSWIM8 (ZSWM8)

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for ZSWIM8 gene (3 alternative transcripts):

NM_001242487.1 NM_001242488.1 NM_015037.3

Unigene Cluster for ZSWIM8:

Zinc finger, SWIM-type containing 8

Hs.65135 [show with all ESTs]

Unigene Representative Sequence: NM_015037

Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23):

ENST00000604729 ENST00000603114 ENST00000446546 ENST00000604524 ENST00000605216

ENST00000433366 ENST00000451629 ENST00000492395(uc001jvh.3) ENST00000431225

ENST00000603187 ENST00000412198(uc009xrn.2) ENST00000604754 ENST00000425051

ENST00000489234 ENST00000487278 ENST00000603409 ENST00000604165 ENST00000603195

miRNA Products:		Block miRNA regulation of human, mouse, rat ZSWIM8 using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate ZSWIM8
		SwitchGear 3'UTR luciferase reporter plasmid: ZSWIM8 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for ZSWIM8
		Predesigned siRNA for gene silencing in human, mouse, rat ZSWIM8

Clone Products:		OriGene clones in human, mouse for ZSWIM8 (see all 5) OriGene ORF clones in mouse, rat for ZSWIM8 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for ZSWIM8
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZSWIM8
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSWIM8

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for ZSWIM8
		Search Pre-validated RT² qPCR Primer Assays in human, mouse, rat ZSWIM8
		QuantiTect SYBR Green Assays in human, mouse, rat ZSWIM8
		QuantiFast Probe-based Assays in human, mouse, rat ZSWIM8

Additional mRNA sequence:

AB020720.2 AK023742.1 AK309136.1 AL133662.1 BC036835.1 BC040726.1 BC063694.1 BC111006.1

BC113914.1 BC117205.1 BC151206.1

15 DOTS entries:

DT.416369 DT.99992750 DT.92439537 DT.95276797 DT.75102940 DT.100688773 DT.121293079 DT.100786274

DT.86841533 DT.95276789 DT.100786272 DT.431157 DT.75109951 DT.92439530 DT.92439536

Selected AceView cDNA sequences (see all 213):

BE778038 BQ640275 BQ227817 BQ676406 BE833282 CD742672 BU786041 BQ786940

AI702493 BI757242 AI589502 AI383152 BU621409 BF529727 BQ575546 AI991978

BE046486 AL133662 BU743235 AI992285 CR610954 AA443585 BE385083 BU685743

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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ZSWIM8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

ZSWIM8 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database


Heart (Cardiovascular System) fully expand to see all 2 entries
Atrioventricular Canal Cells Atrioventricular Canal
Outflow Tract

ZSWIM8 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

ZSWIM8 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.65135

Custom PCR Arrays for ZSWIM8

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for ZSWIM8
		Search Pre-validated RT² qPCR Primer Assays in human, mouse, rat ZSWIM8
		QuantiTect SYBR Green Assays in human, mouse, rat ZSWIM8
		QuantiFast Probe-based Assays in human, mouse, rat ZSWIM8

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSWIM8

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for ZSWIM8 gene from Selected species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Zswim8^{1 , 5}	RIKEN cDNA 2310021P13 gene⁵ zinc finger SWIM-type containing 8¹	91.24(n)¹ 97.49(a)¹		14 (11.53 cM)⁵ 268721¹ NM_001252082.1¹ NP_001239011.1¹ 20707552⁵
chicken (Gallus gallus)	Aves	KIAA0913¹	KIAA0913	73.81(n) 82.45(a)		423739 NM_001195600.1 NP_001182529.1
lizard (Anolis carolinensis)	Reptilia	ZSWIM8⁶	zinc finger, SWIM-type containing 8	82(a)	1 ↔ 1	GL343196.1(1364281-1414841)
African clawed frog (Xenopus laevis)	Amphibia	Xl.13157²	Xenopus laevis transcribed sequences	78(n)		CD326856.1
zebrafish (Danio rerio)	Actinopterygii	zswim8¹	zinc finger, SWIM-type containing 8	70.27(n) 77.52(a)		100148379 NM_001145707.1 NP_001139179.1
fruit fly (Drosophila melanogaster)	Insecta	CG34401⁶	--	40(a)	1 ↔ 1	X(18757983-18778108)

ENSEMBL Gene Tree for ZSWIM8 (if available)
TreeFam Gene Tree for ZSWIM8 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for ZSWIM8 gene

ZSWIM4² ZSWIM5² ZSWIM6²

1 SIMAP similar gene for ZSWIM8 using alignment to 10 protein entries: ZSWM8_HUMAN (see all proteins):

KIAA0913

ZSWIM8 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs76092439^1,2	C,F	--	75543943(+)	`CCACTG/AGACTC`	3	--	us2k¹		1		EA	120
rs183914357^1,2		--	75544012(+)	`TCTCAA/GGTTAG`	3	--	us2k¹		0	--	--	--	--
rs187766648^1,2		--	75544022(+)	`GCTGCC/TTAGTT`	3	--	us2k¹		0	--	--	--	--
rs192445390^1,2		--	75544151(+)	`GTCTCA/GCTCTG`	3	--	us2k¹		0	--	--	--	--
rs34498422^1,2	C,F	--	75544307(+)	`AGAGAC/TGGGGT`	3	--	us2k¹		2		NA	4
rs11595202^1,2	H	--	75544399(+)	`ggcgtA/Gagcca`	3	--	us2k¹		0	--	--	--	--
rs184831836^1,2		--	75544499(+)	`CCAACA/TGAAAT`	3	--	us2k¹		0	--	--	--	--
rs189764550^1,2		--	75544586(+)	`ATACCA/GTGTTA`	3	--	us2k¹		0	--	--	--	--
rs79432392^1,2	F	--	75544649(+)	`ATTATG/AATAGT`	3	--	us2k¹		1		NA	120
rs151005515^1,2		--	75544800(+)	`GTAAAC/TGATCT`	3	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ZSWIM8 (75545340 - 75561556 bp)

Structural Variations
Database of Genomic Variants (DGV) variations for ZSWIM8: --

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing ZSWIM8

DNA2.0 Custom Variant and Variant Library Synthesis for ZSWIM8

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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4 diseases for ZSWIM8:
About MalaCards

choroiditis ataxia alzheimer's disease malaria

ZSWIM8 for disorders About GeneDecksing

Export disorders for ZSWIM8 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for ZSWIM8 gene, integrated from 10 sources (see all 18):
(articles sorted by number of sources associating them with ZSWIM8)

Utopia: connect your pdf to the dynamic
world of online information

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)^{1, 2} Nagase T.... Ohara O. (DNA Res. 1998)
Proteomic analysis of the NOS2 interactome in human airway epithelial cells. (PubMed id 23438482)¹ Foster M.W....Marshall H.E. (Nitric Oxide 2013)
Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. (PubMed id 22586326)¹ Tsai Y.C.... Cristea I.M. (Mol. Cell. Proteomics 2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PubMed id 21987572)¹ Lee K.A....Doedens J.R. (J. Biol. Chem. 2011)
Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (amp 2011)
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)² Olsen J.V....Mann M. (Sci. Signal. 2010)
Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)¹ Bennett E.J....Harper J.W. (Cell 2010)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 23053	HGNC: 23528	AceView: KIAA0913	Ensembl:ENSG00000214655	euGenes: HUgn23053
ECgene: ZSWIM8	H-InvDB: ZSWIM8

(According to HUGE)
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HUGE: KIAA0913

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for ZSWIM8	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ZSWIM8 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for ZSWIM8 gene:
Search GeneIP for patents involving ZSWIM8

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for ZSWIM8
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	OriGene Custom Mass Spec		OriGene clones in human, mouse for ZSWIM8
	OriGene qSTAR qPCR primer pairs in human, mouse for ZSWIM8		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
	OriGene ORF clones in mouse, rat for ZSWIM8		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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	Block miRNA regulation of human, mouse, rat ZSWIM8 using miScript Target Protectors		SeqTarget long-range PCR primers for resequencing ZSWIM8
	DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZSWIM8		Predesigned siRNA for gene silencing in human, mouse, rat ZSWIM8
	QuantiFast Probe-based Assays in human, mouse, rat ZSWIM8		QuantiTect SYBR Green Assays in human, mouse, rat ZSWIM8
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	GenScript Custom Purified and Recombinant Proteins Services for ZSWIM8		GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for ZSWIM8
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSWIM8

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GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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Hot genes Disease genes ZSWIM8 gene at Home site.

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ZSWIM8 Gene

Zinc Finger, SWIM-Type Containing 8

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ZSWIM8 Gene

Zinc Finger, SWIM-Type Containing 8

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