Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZSWIM5 Gene

Aliases for ZSWIM5 Gene

  • Zinc Finger, SWIM-Type Containing 5 2 3
  • KIAA1511 4

External Ids for ZSWIM5 Gene

Previous GeneCards Identifiers for ZSWIM5 Gene

  • GC01M044895
  • GC01M045151
  • GC01M045254
  • GC01M045482
  • GC01M043594

Summaries for ZSWIM5 Gene

GeneCards Summary for ZSWIM5 Gene

ZSWIM5 (Zinc Finger, SWIM-Type Containing 5) is a Protein Coding gene. An important paralog of this gene is ZSWIM6.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSWIM5 Gene

Genomics for ZSWIM5 Gene

Regulatory Elements for ZSWIM5 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZSWIM5 Gene

Start:
45,016,399 bp from pter
End:
45,306,209 bp from pter
Size:
289,811 bases
Orientation:
Minus strand

Genomic View for ZSWIM5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZSWIM5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSWIM5 Gene

Proteins for ZSWIM5 Gene

  • Protein details for ZSWIM5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P217-ZSWM5_HUMAN
    Recommended name:
    Zinc finger SWIM domain-containing protein 5
    Protein Accession:
    Q9P217
    Secondary Accessions:
    • Q5SXQ9

    Protein attributes for ZSWIM5 Gene

    Size:
    1185 amino acids
    Molecular mass:
    130634 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA96035.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZSWIM5 Gene

Proteomics data for ZSWIM5 Gene at MOPED

Post-translational modifications for ZSWIM5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZSWIM5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZSWIM5 Gene

Domains for ZSWIM5 Gene

Gene Families for ZSWIM5 Gene

HGNC:
  • ZSWIM :Zinc fingers, SWIM-type

Protein Domains for ZSWIM5 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for ZSWIM5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9P217

UniProtKB/Swiss-Prot:

ZSWM5_HUMAN :
  • Q9P217
Similarity:
  • Contains 1 SWIM-type zinc finger.
genes like me logo Genes that share domains with ZSWIM5: view

Function for ZSWIM5 Gene

Gene Ontology (GO) - Molecular Function for ZSWIM5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZSWIM5: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZSWIM5

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZSWIM5 Gene

Localization for ZSWIM5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZSWIM5 Gene COMPARTMENTS Subcellular localization image for ZSWIM5 gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for ZSWIM5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 22664934
genes like me logo Genes that share ontologies with ZSWIM5: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZSWIM5 Gene

Pathways for ZSWIM5 Gene

SuperPathways for ZSWIM5 Gene

No Data Available

Interacting Proteins for ZSWIM5 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000352614%0d%0a9606.ENSP00000262982%0d%0a
Selected Interacting proteins: ENSP00000352614 for ZSWIM5 Gene via STRING

Symbol External ID(s) Details
CSE1L

Gene Ontology (GO) - Biological Process for ZSWIM5 Gene

None

No data available for Pathways by source for ZSWIM5 Gene

Transcripts for ZSWIM5 Gene

mRNA/cDNA for ZSWIM5 Gene

(22) Selected AceView cDNA sequences:
(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZSWIM5 Gene

Zinc finger, SWIM-type containing 5:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZSWIM5

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZSWIM5

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSWIM5 Gene

No ASD Table

Relevant External Links for ZSWIM5 Gene

GeneLoc Exon Structure for
ZSWIM5
ECgene alternative splicing isoforms for
ZSWIM5

Expression for ZSWIM5 Gene

mRNA expression in normal human tissues for ZSWIM5 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZSWIM5 Gene

This gene is overexpressed in Adrenal Gland (4.9).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ZSWIM5 Gene

SOURCE GeneReport for Unigene cluster for ZSWIM5 Gene Hs.656613

genes like me logo Genes that share expressions with ZSWIM5: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for ZSWIM5 Gene

Orthologs for ZSWIM5 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZSWIM5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZSWIM5 35
  • 99.75 (n)
  • 99.83 (a)
ZSWIM5 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZSWIM5 35
  • 92.63 (n)
  • 97.27 (a)
ZSWIM5 36
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZSWIM5 35
  • 89.04 (n)
  • 84.93 (a)
ZSWIM5 36
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zswim5 35
  • 91.34 (n)
  • 95.86 (a)
Zswim5 16
Zswim5 36
  • 96 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 87 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Zswim5 35
  • 91.07 (n)
  • 96.71 (a)
chicken
(Gallus gallus)
Aves -- 36
  • 88 (a)
ManyToMany
ZSWIM5 35
  • 79.16 (n)
  • 89.6 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 74 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia zswim5 35
  • 74.03 (n)
  • 84.4 (a)
zebrafish
(Danio rerio)
Actinopterygii zswim5 35
  • 75.2 (n)
  • 85.93 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010062 35
  • 57.63 (n)
  • 58.3 (a)
worm
(Caenorhabditis elegans)
Secernentea ebax-1 36
  • 13 (a)
OneToMany
Species with no ortholog for ZSWIM5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZSWIM5 Gene

ENSEMBL:
Gene Tree for ZSWIM5 (if available)
TreeFam:
Gene Tree for ZSWIM5 (if available)

Paralogs for ZSWIM5 Gene

Paralogs for ZSWIM5 Gene

Selected SIMAP similar genes for ZSWIM5 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZSWIM5 Gene

genes like me logo Genes that share paralogs with ZSWIM5: view

Variants for ZSWIM5 Gene

Sequence variations from dbSNP and Humsavar for ZSWIM5 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs168315 -- 45,090,180(+) CTAGC(A/G)AAATT intron-variant
rs168316 -- 45,146,527(+) ctccg(C/T)ttccc intron-variant
rs173208 -- 45,093,880(+) gctcc(A/G)ttacc intron-variant
rs180850 -- 45,146,584(+) acagg(G/T)gtaca intron-variant
rs186974 -- 45,146,677(+) tcaag(G/T)gatcc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZSWIM5 Gene

Variant ID Type Subtype PubMed ID
nsv524385 CNV Loss 19592680
esv2664539 CNV Deletion 23128226
esv2747785 CNV Deletion 23290073
esv2674119 CNV Deletion 23128226
esv24105 CNV Loss 19812545

Relevant External Links for ZSWIM5 Gene

HapMap Linkage Disequilibrium report
ZSWIM5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSWIM5 Gene

Disorders for ZSWIM5 Gene

Relevant External Links for ZSWIM5

Genetic Association Database (GAD)
ZSWIM5
Human Genome Epidemiology (HuGE) Navigator
ZSWIM5
genes like me logo Genes that share disorders with ZSWIM5: view

No data available for UniProtKB/Swiss-Prot for ZSWIM5 Gene

Publications for ZSWIM5 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10819331) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  4. Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach. (PMID: 22664934) BAPhm D. … Grus F.H. (Oncol. Rep. 2012) 3
  5. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PMID: 17903296) Kiel D.P. … Karasik D. (BMC Med. Genet. 2007) 48

Products for ZSWIM5 Gene

Sources for ZSWIM5 Gene

Back to Top

Content