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Aliases for ZSWIM3 Gene

Aliases for ZSWIM3 Gene

  • Zinc Finger SWIM-Type Containing 3 2 3 5
  • Protein Phosphatase 1, Regulatory Subunit 174 2 3
  • C20orf164 3 4
  • Zinc Finger SWIM Domain-Containing Protein 3 3
  • Zinc Finger, SWIM Domain Containing 3 3
  • Chromosome 20 Open Reading Frame 164 2
  • PPP1R174 3

External Ids for ZSWIM3 Gene

Previous HGNC Symbols for ZSWIM3 Gene

  • C20orf164

Previous GeneCards Identifiers for ZSWIM3 Gene

  • GC20P045171
  • GC20P043919
  • GC20P044486
  • GC20P041227

Summaries for ZSWIM3 Gene

GeneCards Summary for ZSWIM3 Gene

ZSWIM3 (Zinc Finger SWIM-Type Containing 3) is a Protein Coding gene. GO annotations related to this gene include transposase activity. An important paralog of this gene is ZSWIM1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSWIM3 Gene

Genomics for ZSWIM3 Gene

Regulatory Elements for ZSWIM3 Gene

Enhancers for ZSWIM3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ZSWIM3 on UCSC Golden Path with GeneCards custom track

Promoters for ZSWIM3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for ZSWIM3 Gene

45,857,581 bp from pter
45,879,131 bp from pter
21,551 bases
Plus strand

Genomic View for ZSWIM3 Gene

Genes around ZSWIM3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSWIM3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSWIM3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSWIM3 Gene

Proteins for ZSWIM3 Gene

  • Protein details for ZSWIM3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger SWIM domain-containing protein 3
    Protein Accession:
    Secondary Accessions:
    • Q9BR13

    Protein attributes for ZSWIM3 Gene

    696 amino acids
    Molecular mass:
    79454 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZSWIM3 Gene

Post-translational modifications for ZSWIM3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZSWIM3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZSWIM3 Gene

Domains & Families for ZSWIM3 Gene

Gene Families for ZSWIM3 Gene

Protein Domains for ZSWIM3 Gene


Suggested Antigen Peptide Sequences for ZSWIM3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 SWIM-type zinc finger.
  • Contains 1 SWIM-type zinc finger.
genes like me logo Genes that share domains with ZSWIM3: view

Function for ZSWIM3 Gene

Gene Ontology (GO) - Molecular Function for ZSWIM3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZSWIM3: view
genes like me logo Genes that share phenotypes with ZSWIM3: view

Animal Model Products

CRISPR Products

miRNA for ZSWIM3 Gene

miRTarBase miRNAs that target ZSWIM3

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZSWIM3 Gene

Localization for ZSWIM3 Gene

Subcellular locations from

Jensen Localization Image for ZSWIM3 Gene COMPARTMENTS Subcellular localization image for ZSWIM3 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZSWIM3 Gene

Pathways & Interactions for ZSWIM3 Gene

SuperPathways for ZSWIM3 Gene

No Data Available

Interacting Proteins for ZSWIM3 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000255152 Q96MP5-ZSWM3_HUMAN for ZSWIM3 Gene via STRING IID

Gene Ontology (GO) - Biological Process for ZSWIM3 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZSWIM3 Gene

Drugs & Compounds for ZSWIM3 Gene

No Compound Related Data Available

Transcripts for ZSWIM3 Gene

mRNA/cDNA for ZSWIM3 Gene

Unigene Clusters for ZSWIM3 Gene

Zinc finger, SWIM-type containing 3:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSWIM3 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b
SP2: -

Relevant External Links for ZSWIM3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZSWIM3 Gene

mRNA expression in normal human tissues for ZSWIM3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZSWIM3 Gene

Protein tissue co-expression partners for ZSWIM3 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZSWIM3 Gene:


SOURCE GeneReport for Unigene cluster for ZSWIM3 Gene:

genes like me logo Genes that share expression patterns with ZSWIM3: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZSWIM3 Gene

Orthologs for ZSWIM3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZSWIM3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZSWIM3 34
  • 83.87 (n)
  • 79.38 (a)
  • 74 (a)
(Canis familiaris)
Mammalia ZSWIM3 34
  • 86.95 (n)
  • 87.05 (a)
  • 87 (a)
(Mus musculus)
Mammalia Zswim3 34
  • 84.03 (n)
  • 80.61 (a)
Zswim3 16
Zswim3 35
  • 80 (a)
(Pan troglodytes)
Mammalia ZSWIM3 34
  • 99.62 (n)
  • 99.28 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Zswim3 34
  • 84.13 (n)
  • 81.82 (a)
(Monodelphis domestica)
Mammalia ZSWIM3 35
  • 62 (a)
(Gallus gallus)
Aves ZSWIM3 34
  • 56.63 (n)
  • 44.73 (a)
  • 43 (a)
(Anolis carolinensis)
Reptilia ZSWIM3 35
  • 45 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.5469 34
zswim3 34
  • 53.53 (n)
  • 39.76 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.15174 34
Species where no ortholog for ZSWIM3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSWIM3 Gene

Gene Tree for ZSWIM3 (if available)
Gene Tree for ZSWIM3 (if available)

Paralogs for ZSWIM3 Gene

Paralogs for ZSWIM3 Gene

(1) SIMAP similar genes for ZSWIM3 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZSWIM3: view

Variants for ZSWIM3 Gene

Sequence variations from dbSNP and Humsavar for ZSWIM3 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs2903808 - 45,877,334(+) GACAG(C/T)CACCT nc-transcript-variant, reference, missense
rs35928298 - 45,877,429(+) ATTAC(C/T)GGGCT nc-transcript-variant, reference, missense
rs174746 -- 45,870,732(+) tctgt(C/T)gccca intron-variant
rs197675 -- 45,860,926(+) AATGG(C/T)GTGAG intron-variant
rs515547 -- 45,870,624(+) agaga(G/T)aagaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZSWIM3 Gene

Variant ID Type Subtype PubMed ID
esv2666503 CNV deletion 23128226
nsv1142992 CNV tandem duplication 24896259
nsv179037 CNV deletion 16902084
nsv458993 CNV loss 19166990
nsv517296 CNV loss 19592680
nsv586133 CNV loss 21841781
nsv833990 CNV loss 17160897

Variation tolerance for ZSWIM3 Gene

Residual Variation Intolerance Score: 44.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.82; 47.81% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZSWIM3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSWIM3 Gene

Disorders for ZSWIM3 Gene

Relevant External Links for ZSWIM3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZSWIM3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSWIM3 Gene

Publications for ZSWIM3 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  3. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4 65
  4. Docking motif-guided mapping of the interactome of protein phosphatase-1. (PMID: 19389623) Hendrickx A. … Bollen M. (Chem. Biol. 2009) 3 65
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 65

Products for ZSWIM3 Gene

Sources for ZSWIM3 Gene

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