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Aliases for ZSWIM3 Gene

Aliases for ZSWIM3 Gene

  • Zinc Finger, SWIM-Type Containing 3 2 3
  • C20orf164 3 4
  • Protein Phosphatase 1, Regulatory Subunit 174 3
  • Zinc Finger, SWIM Domain Containing 3 3
  • Chromosome 20 Open Reading Frame 164 2
  • Regulatory Subunit 174 2
  • Protein Phosphatase 1 2
  • PPP1R174 3

External Ids for ZSWIM3 Gene

Previous HGNC Symbols for ZSWIM3 Gene

  • C20orf164

Previous GeneCards Identifiers for ZSWIM3 Gene

  • GC20P045171
  • GC20P043919
  • GC20P044486
  • GC20P041227

Summaries for ZSWIM3 Gene

GeneCards Summary for ZSWIM3 Gene

ZSWIM3 (Zinc Finger, SWIM-Type Containing 3) is a Protein Coding gene. GO annotations related to this gene include transposase activity. An important paralog of this gene is ZSWIM1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSWIM3 Gene

Genomics for ZSWIM3 Gene

Regulatory Elements for ZSWIM3 Gene

Genomic Location for ZSWIM3 Gene

Chromosome:
20
Start:
45,857,581 bp from pter
End:
45,879,131 bp from pter
Size:
21,551 bases
Orientation:
Plus strand

Genomic View for ZSWIM3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZSWIM3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSWIM3 Gene

Proteins for ZSWIM3 Gene

  • Protein details for ZSWIM3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96MP5-ZSWM3_HUMAN
    Recommended name:
    Zinc finger SWIM domain-containing protein 3
    Protein Accession:
    Q96MP5
    Secondary Accessions:
    • Q9BR13

    Protein attributes for ZSWIM3 Gene

    Size:
    696 amino acids
    Molecular mass:
    79454 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZSWIM3 Gene

Proteomics data for ZSWIM3 Gene at MOPED

Post-translational modifications for ZSWIM3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZSWIM3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZSWIM3 Gene

Domains & Families for ZSWIM3 Gene

Gene Families for ZSWIM3 Gene

Protein Domains for ZSWIM3 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for ZSWIM3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96MP5

UniProtKB/Swiss-Prot:

ZSWM3_HUMAN :
  • Contains 1 SWIM-type zinc finger.
Similarity:
  • Contains 1 SWIM-type zinc finger.
genes like me logo Genes that share domains with ZSWIM3: view

Function for ZSWIM3 Gene

Gene Ontology (GO) - Molecular Function for ZSWIM3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZSWIM3: view

Phenotypes for ZSWIM3 Gene

GenomeRNAi human phenotypes for ZSWIM3:
genes like me logo Genes that share phenotypes with ZSWIM3: view

Animal Model Products

miRNA for ZSWIM3 Gene

miRTarBase miRNAs that target ZSWIM3

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZSWIM3 Gene

Localization for ZSWIM3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ZSWIM3 Gene

Pathways & Interactions for ZSWIM3 Gene

SuperPathways for ZSWIM3 Gene

No Data Available

Interacting Proteins for ZSWIM3 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000255152%0d%0a9606.ENSP00000326031%0d%0a
Selected Interacting proteins: ENSP00000255152 for ZSWIM3 Gene via STRING

Symbol External ID(s) Details
PPP1CA

Gene Ontology (GO) - Biological Process for ZSWIM3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZSWIM3 Gene

Drugs & Compounds for ZSWIM3 Gene

No Compound Related Data Available

Transcripts for ZSWIM3 Gene

mRNA/cDNA for ZSWIM3 Gene

Unigene Clusters for ZSWIM3 Gene

Zinc finger, SWIM-type containing 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZSWIM3 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b
SP1:
SP2: -

Relevant External Links for ZSWIM3 Gene

GeneLoc Exon Structure for
ZSWIM3
ECgene alternative splicing isoforms for
ZSWIM3

Expression for ZSWIM3 Gene

mRNA expression in normal human tissues for ZSWIM3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZSWIM3 Gene



SOURCE GeneReport for Unigene cluster for ZSWIM3 Gene Hs.292135

genes like me logo Genes that share expression patterns with ZSWIM3: view

Protein tissue co-expression partners for ZSWIM3 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZSWIM3 Gene

Orthologs for ZSWIM3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZSWIM3 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZSWIM3 35
  • 83.87 (n)
  • 79.38 (a)
ZSWIM3 36
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZSWIM3 35
  • 86.95 (n)
  • 87.05 (a)
ZSWIM3 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zswim3 35
  • 84.03 (n)
  • 80.61 (a)
Zswim3 16
Zswim3 36
  • 80 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZSWIM3 35
  • 99.62 (n)
  • 99.28 (a)
ZSWIM3 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zswim3 35
  • 84.13 (n)
  • 81.82 (a)
oppossum
(Monodelphis domestica)
Mammalia ZSWIM3 36
  • 62 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZSWIM3 35
  • 56.63 (n)
  • 44.73 (a)
ZSWIM3 36
  • 43 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZSWIM3 36
  • 45 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.5469 35
zswim3 35
  • 53.53 (n)
  • 39.76 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.15174 35
Species with no ortholog for ZSWIM3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSWIM3 Gene

ENSEMBL:
Gene Tree for ZSWIM3 (if available)
TreeFam:
Gene Tree for ZSWIM3 (if available)

Paralogs for ZSWIM3 Gene

Paralogs for ZSWIM3 Gene

(1) SIMAP similar genes for ZSWIM3 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZSWIM3: view

Variants for ZSWIM3 Gene

Sequence variations from dbSNP and Humsavar for ZSWIM3 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs174746 -- 45,870,732(+) tctgt(C/T)gccca intron-variant
rs197675 -- 45,860,926(+) AATGG(C/T)GTGAG intron-variant
rs366837 -- 45,877,243(-) CTGGG(A/C/T)GTTCT reference, missense, nc-transcript-variant
rs380988 -- 45,867,455(-) tactg(A/G)ctgta intron-variant
rs515547 -- 45,870,624(+) agaga(G/T)aagaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZSWIM3 Gene

Variant ID Type Subtype PubMed ID
nsv833990 CNV Loss 17160897
nsv458993 CNV Loss 19166990
nsv517296 CNV Loss 19592680
esv2666503 CNV Deletion 23128226
nsv179037 CNV Loss 16902084

Variation tolerance for ZSWIM3 Gene

Residual Variation Intolerance Score: 44.31% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.82; 47.81% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZSWIM3 Gene

HapMap Linkage Disequilibrium report
ZSWIM3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSWIM3 Gene

Disorders for ZSWIM3 Gene

Relevant External Links for ZSWIM3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZSWIM3
genes like me logo Genes that share disorders with ZSWIM3: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSWIM3 Gene

Publications for ZSWIM3 Gene

  1. Docking motif-guided mapping of the interactome of protein phosphatase-1. (PMID: 19389623) Hendrickx A. … Bollen M. (Chem. Biol. 2009) 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for ZSWIM3 Gene

Sources for ZSWIM3 Gene

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