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Aliases for ZSWIM3 Gene

Aliases for ZSWIM3 Gene

  • Zinc Finger SWIM-Type Containing 3 2 3 5
  • Protein Phosphatase 1, Regulatory Subunit 174 2 3
  • C20orf164 3 4
  • Zinc Finger SWIM Domain-Containing Protein 3 3
  • Zinc Finger, SWIM Domain Containing 3 3
  • Chromosome 20 Open Reading Frame 164 2
  • PPP1R174 3

External Ids for ZSWIM3 Gene

Previous HGNC Symbols for ZSWIM3 Gene

  • C20orf164

Previous GeneCards Identifiers for ZSWIM3 Gene

  • GC20P045171
  • GC20P043919
  • GC20P044486
  • GC20P041227

Summaries for ZSWIM3 Gene

GeneCards Summary for ZSWIM3 Gene

ZSWIM3 (Zinc Finger SWIM-Type Containing 3) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transposase activity. An important paralog of this gene is ZSWIM1.

Additional gene information for ZSWIM3 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSWIM3 Gene

Genomics for ZSWIM3 Gene

GeneHancer (GH) Regulatory Elements for ZSWIM3 Gene

Promoters and enhancers for ZSWIM3 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20I045855 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 550.8 -0.2 -241 2.8 HDGF PKNOX1 FOXA2 SMAD1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZSWIM3 ACOT8 NCOA5 TP53RK WFDC3 SPATA25 RPS2P7 PLTP ENSG00000277051 GC20M045858
GH20I045933 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 11.9 +78.7 78749 6.3 CLOCK MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 PCIF1 SNX21 NCOA5 TP53RK SPATA25 ZNF335 PLTP SLC35C2 WFDC3 ENSG00000271984
GH20I045909 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 11.4 +53.4 53376 3.7 HDGF PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 YY1 POLR2B ZNF766 PLTP SLC12A5-AS1 ZSWIM3 ACOT8 TNNC2 SNX21 UBE2C WFDC3 DNTTIP1 SLC12A5
GH20I045817 Enhancer 1.2 Ensembl ENCODE dbSUPER 11.8 -39.7 -39660 1.5 HDAC1 KLF17 ZEB1 ZNF335 TCF12 ZNF121 GLIS2 ZNF213 ZNF366 SCRT2 WFDC3 PLTP NCOA5 ACOT8 ZSWIM3 DNTTIP1 ZSWIM1 NEURL2 SPATA25 CTSA
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZSWIM3 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZSWIM3 gene promoter:

Genomic Locations for ZSWIM3 Gene

Genomic Locations for ZSWIM3 Gene
21,551 bases
Plus strand

Genomic View for ZSWIM3 Gene

Genes around ZSWIM3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSWIM3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSWIM3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSWIM3 Gene

Proteins for ZSWIM3 Gene

  • Protein details for ZSWIM3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger SWIM domain-containing protein 3
    Protein Accession:
    Secondary Accessions:
    • Q9BR13

    Protein attributes for ZSWIM3 Gene

    696 amino acids
    Molecular mass:
    79454 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZSWIM3 Gene

Post-translational modifications for ZSWIM3 Gene

No Post-translational modifications

Other Protein References for ZSWIM3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZSWIM3 Gene

Domains & Families for ZSWIM3 Gene

Gene Families for ZSWIM3 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZSWIM3 Gene


Suggested Antigen Peptide Sequences for ZSWIM3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZSWIM3: view

No data available for UniProtKB/Swiss-Prot for ZSWIM3 Gene

Function for ZSWIM3 Gene

Phenotypes From GWAS Catalog for ZSWIM3 Gene

Gene Ontology (GO) - Molecular Function for ZSWIM3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSWIM3: view
genes like me logo Genes that share phenotypes with ZSWIM3: view

Animal Model Products

miRNA for ZSWIM3 Gene

miRTarBase miRNAs that target ZSWIM3

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZSWIM3 Gene

Localization for ZSWIM3 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZSWIM3 gene
Compartment Confidence
nucleus 3
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoli fibrillar center (2)
  • Vesicles (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZSWIM3 Gene

Pathways & Interactions for ZSWIM3 Gene

SuperPathways for ZSWIM3 Gene

No Data Available

Interacting Proteins for ZSWIM3 Gene

Selected Interacting proteins: Q96MP5-ZSWM3_HUMAN for ZSWIM3 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for ZSWIM3 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZSWIM3 Gene

Drugs & Compounds for ZSWIM3 Gene

No Compound Related Data Available

Transcripts for ZSWIM3 Gene

mRNA/cDNA for ZSWIM3 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(53) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZSWIM3 Gene

Zinc finger, SWIM-type containing 3:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSWIM3 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b
SP2: -

Relevant External Links for ZSWIM3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZSWIM3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZSWIM3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZSWIM3 Gene

Protein tissue co-expression partners for ZSWIM3 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZSWIM3 Gene:


SOURCE GeneReport for Unigene cluster for ZSWIM3 Gene:


Evidence on tissue expression from TISSUES for ZSWIM3 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZSWIM3: view

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZSWIM3 Gene

Orthologs for ZSWIM3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZSWIM3 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZSWIM3 33 34
  • 99.62 (n)
(Canis familiaris)
Mammalia ZSWIM3 33 34
  • 86.95 (n)
(Rattus norvegicus)
Mammalia Zswim3 33
  • 84.13 (n)
(Mus musculus)
Mammalia Zswim3 33 16 34
  • 84.03 (n)
(Bos Taurus)
Mammalia ZSWIM3 33 34
  • 83.87 (n)
(Monodelphis domestica)
Mammalia ZSWIM3 34
  • 62 (a)
(Gallus gallus)
Aves ZSWIM3 33 34
  • 56.63 (n)
(Anolis carolinensis)
Reptilia ZSWIM3 34
  • 45 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia zswim3 33
  • 53.53 (n)
Str.5469 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.15174 33
Species where no ortholog for ZSWIM3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSWIM3 Gene

Gene Tree for ZSWIM3 (if available)
Gene Tree for ZSWIM3 (if available)

Paralogs for ZSWIM3 Gene

Paralogs for ZSWIM3 Gene

(1) SIMAP similar genes for ZSWIM3 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZSWIM3: view

Variants for ZSWIM3 Gene

Sequence variations from dbSNP and Humsavar for ZSWIM3 Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs1000015176 -- 45,867,433(+) T/C intron_variant
rs1000196622 -- 45,871,499(+) C/T intron_variant
rs1000312872 -- 45,871,148(+) A/C intron_variant
rs1000530795 -- 45,869,962(+) G/A/T intron_variant
rs1000645319 -- 45,869,669(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZSWIM3 Gene

Variant ID Type Subtype PubMed ID
esv2666503 CNV deletion 23128226
nsv1142992 CNV tandem duplication 24896259
nsv179037 CNV deletion 16902084
nsv458993 CNV loss 19166990
nsv517296 CNV loss 19592680
nsv586133 CNV loss 21841781
nsv833990 CNV loss 17160897

Variation tolerance for ZSWIM3 Gene

Residual Variation Intolerance Score: 44.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.82; 47.81% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZSWIM3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSWIM3 Gene

Disorders for ZSWIM3 Gene

Additional Disease Information for ZSWIM3

No disorders were found for ZSWIM3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSWIM3 Gene

Publications for ZSWIM3 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P … Rogers J (Nature 2001) 3 4 58
  4. Docking motif-guided mapping of the interactome of protein phosphatase-1. (PMID: 19389623) Hendrickx A … Bollen M (Chemistry & biology 2009) 3 58
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58

Products for ZSWIM3 Gene

Sources for ZSWIM3 Gene

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