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ZSWIM2 Gene

protein-coding   GIFtS: 45
GCID: GC02M187693

Zinc Finger, SWIM-Type Containing 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger, SWIM-Type Containing 21 2     ZZ-Type Zinc Finger-Containing Protein 22 3
Zinc Finger SWIM Domain-Containing Protein 22 3     E3 Ubiquitin-Protein Ligase ZSWIM22
MEX2 3     Zinc Finger, SWIM Domain Containing 22
ZZZ22 3     EC 6.3.2.-3
MEKK1-Related Protein X2 3     

External Ids:    HGNC: 309901   Entrez Gene: 1511122   Ensembl: ENSG000001630127   UniProtKB: Q8NEG53   

Export aliases for ZSWIM2 gene to outside databases

Previous GC identifers: GC02M187895 GC02M187894 GC02M187517 GC02M187400 GC02M179552


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZSWIM2 Gene:
ZSWIM2 (zinc finger, SWIM-type containing 2) is a protein-coding gene. Diseases associated with ZSWIM2 include conjunctivitis, and fanconi's anemia. GO annotations related to this gene include ubiquitin-protein ligase activity and protein self-association.

UniProtKB/Swiss-Prot: ZSWM2_HUMAN, Q8NEG5
Function: E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis.
Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZSWIM2 gene promoter:
         STAT5B   Nkx3-1   Nkx3-1 v4   MEF-2   Nkx3-1 v1   Nkx3-1 v2   HEN1   MEF-2A   Nkx3-1 v3   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZSWIM2 promoter sequence
   Search Chromatin IP Primers for ZSWIM2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZSWIM2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q32.1   Ensembl cytogenetic band:  2q32.1   HGNC cytogenetic band: 2q32.2

ZSWIM2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZSWIM2 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M187693:  view genomic region     (about GC identifiers)

Start:
187,692,207 bp from pter      End:
187,713,935 bp from pter
Size:
21,729 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ZSWM2_HUMAN, Q8NEG5 (See protein sequence)
Recommended Name: E3 ubiquitin-protein ligase ZSWIM2  
Size: 633 amino acids; 72732 Da
Subunit: Dimer (By similarity). Interacts with UBE2D1 (By similarity)
1 PDB 3D structure from and Proteopedia for ZSWIM2:
2DIP (3D)    
Secondary accessions: B3KXV6 Q53SI3 Q57ZY3

Explore the universe of human proteins at neXtProt for ZSWIM2: NX_Q8NEG5

Explore proteomics data for ZSWIM2 at MOPED

Post-translational modifications: 

  • Polyubiquitinated. Polyubiquitination is followed by degradation via the proteasome (By similarity)1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZSWIM2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_872327.2  
    ENSEMBL proteins: 
     ENSP00000295131   ENSP00000400595  

    ZSWIM2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZSWIM: Zinc fingers, SWIM-type
    ZZZ: Zinc fingers, ZZ-type

    4 InterPro protein domains:
     IPR001841 Znf_RING
     IPR007527 Znf_SWIM
     IPR013083 Znf_RING/FYVE/PHD
     IPR000433 Znf_ZZ

    Graphical View of Domain Structure for InterPro Entry Q8NEG5

    ProtoNet protein and cluster: Q8NEG5

    2 Blocks protein domains:
    IPB000433 Zn-finger
    IPB001841 Zn-finger


    UniProtKB/Swiss-Prot: ZSWM2_HUMAN, Q8NEG5
    Domain: The SWIM-type zinc finger is reqiered for ubiquitination activity (By similarity)
    Similarity: Contains 2 RING-type zinc fingers
    Similarity: Contains 1 SWIM-type zinc finger
    Similarity: Contains 1 ZZ-type zinc finger


    ZSWIM2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZSWM2_HUMAN, Q8NEG5
    Function: E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis.
    Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes (By similarity)

         Enzyme Number (IUBMB): EC 6.3.2.-1

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004842ubiquitin-protein ligase activity IEA--
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0043621protein self-association IEA--
         
    ZSWIM2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZSWIM2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZSWIM2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZSWIM2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZSWIM2

    miRNA
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    1 qRT-PCR Assays for microRNA that regulate ZSWIM2:
    hsa-miR-3671
    SwitchGear 3'UTR luciferase reporter plasmidZSWIM2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ZSWIM2
    Predesigned siRNA for gene silencing in human, mouse, rat ZSWIM2

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: ZSWIM2 (NM_182521)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZSWIM2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSWIM2

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSWIM2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol1
    mitochondrion1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZSWIM2
    Interactions:

        Search GeneGlobe Interaction Network for ZSWIM2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    Selected Interacting proteins for ZSWIM2 (Q8NEG52, 3 ENSP000002951314) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAGEA11P433642, 3, ENSP000003473584MINT-68004 I2D: score=4 STRING: ENSP00000347358
    UBE2UQ5VVX93, ENSP000003601164I2D: score=2 STRING: ENSP00000360116
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    CWC22ENSP000003870064STRING: ENSP00000387006
    POLR2BENSP000003127354STRING: ENSP00000312735
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    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000209protein polyubiquitination IEA--
    GO:0006915apoptotic process IEA--
    GO:0042981regulation of apoptotic process ----
    GO:1902043positive regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA--

    ZSWIM2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZSWIM2 (ZSWM2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ZSWIM2 gene: 
    NM_182521.2  

    Unigene Cluster for ZSWIM2:

    Zinc finger, SWIM-type containing 2
    Hs.375054  [show with all ESTs]
    Unigene Representative Sequence: NM_182521
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000295131(uc002upu.1) ENST00000419862
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZSWIM2 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ZSWIM2:
    hsa-miR-3671
    SwitchGear 3'UTR luciferase reporter plasmidZSWIM2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZSWIM2
    Predesigned siRNA for gene silencing in human, mouse, rat ZSWIM2
    Clone
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    GenScript: all cDNA clones in your preferred vector: ZSWIM2 (NM_182521)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZSWIM2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSWIM2
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZSWIM2
      QuantiTect SYBR Green Assays in human, mouse, rat ZSWIM2
      QuantiFast Probe-based Assays in human, mouse, rat ZSWIM2

    Additional mRNA sequence: 

    AK128006.1 BC031094.1 

    1 DOTS entry:

    DT.101979115 

    6 AceView cDNA sequences:

    BC031094 AK128006 BU852709 NM_182521 BM807593 BI562507 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for ZSWIM2    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
    SP1:              -                                                   
    SP2:                                                                  


    ECgene alternative splicing isoforms for ZSWIM2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZSWIM2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATATATTCA
    ZSWIM2 Expression
    About this image

    ZSWIM2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZSWIM2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.375054
        Custom PCR Arrays for ZSWIM2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSWIM2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ZSWIM2 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zswim21 , 5 zinc finger, SWIM domain containing 25
    zinc finger SWIM-type containing 21
    77.8(n)1
    68.68(a)1
      2 (49.33 cM)5
    718611  NM_027964.21  NP_082240.11 
     839150795 
    lizard
    (Anolis carolinensis)
    Reptilia ZSWIM26
    zinc finger, SWIM-type containing 2
    56(a)
    1 ↔ 1
    GL343737.1(200968-210800)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1656511 zgc:165651 55.11(n)
    46.46(a)
      561301  NM_001100143.1  NP_001093613.1 


    ENSEMBL Gene Tree for ZSWIM2 (if available)
    TreeFam Gene Tree for ZSWIM2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZSWIM2 (see all 575)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs67368461,2
    C,F,A,H--187691857(+) ATTCTC/TTTCAA 1 -- ds500111Minor allele frequency- T:0.17NS EA WA NA CSA 784
    rs1171072661,2
    C,F--187691896(+) GTTTCA/CTAGAC 1 -- ds50011Minor allele frequency- C:0.04EA 120
    rs1431599921,2
    C--187691937(+) ATATC-/ATGTGAT 1 -- ds50010--------
    rs67522001,2
    C,F,H--187691978(+) CAATAT/AAGCAT 1 -- ds500111Minor allele frequency- A:0.17NS EA NA WA CSA 782
    rs752272531,2
    F--187692258(+) GAAAAC/ATCCTT 1 -- ut311Minor allele frequency- A:0.08WA 118
    rs341551031,2
    C--187692280(+) TTTTT-/TATAGG 1 -- ut310--------
    rs76008761,2
    C,F--187692285(+) GTTTTT/GTTTTA 1 -- ut312Minor allele frequency- G:0.08WA 120
    rs126160531,2
    C,F,H--187692305(+) GGTAAT/CTACTA 1 -- ut3119Minor allele frequency- C:0.18NS EA NA WA CSA 2342
    rs1842934871,2
    --187692344(+) GTACCA/GGGGAG 1 -- ut310--------
    rs1895347781,2
    C--187692374(+) GCTACC/TGTGAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for ZSWIM2 (187692207 - 187713935 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ZSWIM2: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZSWIM2
    DNA2.0 Custom Variant and Variant Library Synthesis for ZSWIM2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for ZSWIM2:    
    About MalaCards
    conjunctivitis    fanconi's anemia    hypertension


    ZSWIM2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ZSWIM2
    Human Genome Epidemiology (HuGE) Navigator: ZSWIM2 (3 documents)

    Export disorders for ZSWIM2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZSWIM2 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with ZSWIM2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (Am. J. Hypertens. 2010)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (Int. J. Mol. Med. 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells. (PubMed id 19850743)1 Vanderwerf S.M....Bagby G.C. (Blood 2009)
    7. A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system. (PubMed id 19690564)1 van Wijk S.J....Timmers H.T. (Mol. Syst. Biol. 2009)
    8. MEX is a testis-specific E3 ubiquitin ligase that promotes death receptor-induced apoptosis. (PubMed id 16522193)1 Nishito Y....NA_A+ez G. (Biochem. J. 2006)
    9. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (Nature 2005)
    10. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 151112 HGNC: 30990 AceView: ZSWIM2 Ensembl:ENSG00000163012 euGenes: HUgn151112
    ECgene: ZSWIM2 H-InvDB: ZSWIM2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZSWIM2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZSWIM2 gene:
    Search GeneIP for patents involving ZSWIM2

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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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