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Aliases for ZSWIM1 Gene

Aliases for ZSWIM1 Gene

  • Zinc Finger, SWIM-Type Containing 1 2 3
  • C20orf162 3 4
  • Zinc Finger SWIM Domain-Containing Protein 1 3
  • Zinc Finger, SWIM Domain Containing 1 3
  • Chromosome 20 Open Reading Frame 162 2

External Ids for ZSWIM1 Gene

Previous HGNC Symbols for ZSWIM1 Gene

  • C20orf162

Previous GeneCards Identifiers for ZSWIM1 Gene

  • GC20P045195
  • GC20P043943
  • GC20P044509
  • GC20P041251

Summaries for ZSWIM1 Gene

GeneCards Summary for ZSWIM1 Gene

ZSWIM1 (Zinc Finger, SWIM-Type Containing 1) is a Protein Coding gene. An important paralog of this gene is ZSWIM3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSWIM1 Gene

Genomics for ZSWIM1 Gene

Regulatory Elements for ZSWIM1 Gene

Genomic Location for ZSWIM1 Gene

Start:
45,880,942 bp from pter
End:
45,885,266 bp from pter
Size:
4,325 bases
Orientation:
Plus strand

Genomic View for ZSWIM1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZSWIM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSWIM1 Gene

Proteins for ZSWIM1 Gene

  • Protein details for ZSWIM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BR11-ZSWM1_HUMAN
    Recommended name:
    Zinc finger SWIM domain-containing protein 1
    Protein Accession:
    Q9BR11
    Secondary Accessions:
    • Q5JZH2
    • Q9BR12
    • Q9BV30

    Protein attributes for ZSWIM1 Gene

    Size:
    485 amino acids
    Molecular mass:
    55071 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZSWIM1 Gene

Proteomics data for ZSWIM1 Gene at MOPED

Post-translational modifications for ZSWIM1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZSWIM1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZSWIM1 Gene

Domains for ZSWIM1 Gene

Gene Families for ZSWIM1 Gene

HGNC:
  • ZSWIM :Zinc fingers, SWIM-type

Protein Domains for ZSWIM1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZSWIM1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BR11

UniProtKB/Swiss-Prot:

ZSWM1_HUMAN :
  • Q9BR11
Similarity:
  • Contains 1 SWIM-type zinc finger.
genes like me logo Genes that share domains with ZSWIM1: view

Function for ZSWIM1 Gene

Gene Ontology (GO) - Molecular Function for ZSWIM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with ZSWIM1: view

Animal Model Products

miRNA for ZSWIM1 Gene

miRTarBase miRNAs that target ZSWIM1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZSWIM1 Gene

Localization for ZSWIM1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZSWIM1 Gene COMPARTMENTS Subcellular localization image for ZSWIM1 gene
Compartment Confidence
cytosol 2
nucleus 2
endoplasmic reticulum 1
mitochondrion 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ZSWIM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZSWIM1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZSWIM1 Gene

Pathways for ZSWIM1 Gene

SuperPathways for ZSWIM1 Gene

No Data Available

Interacting Proteins for ZSWIM1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000361598%0d%0a9606.ENSP00000385269%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000361598 Q9BR11-ZSWM1_HUMAN for ZSWIM1 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for ZSWIM1 Gene

None

No data available for Pathways by source for ZSWIM1 Gene

Transcripts for ZSWIM1 Gene

mRNA/cDNA for ZSWIM1 Gene

Unigene Clusters for ZSWIM1 Gene

Zinc finger, SWIM-type containing 1:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZSWIM1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSWIM1 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c
SP1: - -
SP2: -
SP3:

Relevant External Links for ZSWIM1 Gene

GeneLoc Exon Structure for
ZSWIM1
ECgene alternative splicing isoforms for
ZSWIM1

Expression for ZSWIM1 Gene

mRNA expression in normal human tissues for ZSWIM1 Gene

SOURCE GeneReport for Unigene cluster for ZSWIM1 Gene Hs.517075

genes like me logo Genes that share expressions with ZSWIM1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for ZSWIM1 Gene

Orthologs for ZSWIM1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZSWIM1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZSWIM1 35
  • 85.38 (n)
  • 81.14 (a)
ZSWIM1 36
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZSWIM1 35
  • 89.91 (n)
  • 87.72 (a)
ZSWIM1 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zswim1 35
  • 84.54 (n)
  • 85.05 (a)
Zswim1 16
Zswim1 36
  • 85 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZSWIM1 35
  • 99.44 (n)
  • 99.37 (a)
rat
(Rattus norvegicus)
Mammalia Zswim1 35
  • 85.05 (n)
  • 83.96 (a)
oppossum
(Monodelphis domestica)
Mammalia ZSWIM1 36
  • 60 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZSWIM1 35
  • 57.03 (n)
  • 46.33 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia zswim1 35
  • 51.55 (n)
  • 38.39 (a)
Species with no ortholog for ZSWIM1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSWIM1 Gene

ENSEMBL:
Gene Tree for ZSWIM1 (if available)
TreeFam:
Gene Tree for ZSWIM1 (if available)

Paralogs for ZSWIM1 Gene

Paralogs for ZSWIM1 Gene

Selected SIMAP similar genes for ZSWIM1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZSWIM1: view

Variants for ZSWIM1 Gene

Sequence variations from dbSNP and Humsavar for ZSWIM1 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs191805 -- 45,880,903(-) TATAT(A/T)TTTTT upstream-variant-2KB
rs398850 -- 45,881,856(+) ttatt(G/T)tattt intron-variant
rs1133368 -- 45,884,364(+) TTTTT(C/T)TTTTT utr-variant-3-prime
rs1133370 -- 45,884,385(+) TGAGA(A/G)GGGGT utr-variant-3-prime, downstream-variant-500B
rs1133371 -- 45,884,388(+) GAGGG(A/G)GTCTG utr-variant-3-prime, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZSWIM1 Gene

Variant ID Type Subtype PubMed ID
nsv833990 CNV Loss 17160897
nsv517296 CNV Loss 19592680

Relevant External Links for ZSWIM1 Gene

HapMap Linkage Disequilibrium report
ZSWIM1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSWIM1 Gene

Disorders for ZSWIM1 Gene

No disorders were found for ZSWIM1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZSWIM1 Gene

Publications for ZSWIM1 Gene

  1. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. ZSWIM1: a novel biomarker in T helper cell differentiation. (PMID: 24508175) Ko K.K. … Hogarth P.M. (Immunol. Lett. 2014) 2 3
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for ZSWIM1 Gene

Sources for ZSWIM1 Gene

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