ZSWIM1 Gene
protein-coding GIFtS: 44
GCID: GC20P044509
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zinc finger, SWIM-type containing 1(Previous name: chromosome 20 open reading frame 162 )
(Previous symbol: C20orf162)
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Aliases
for ZSWIM1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger, SWIM-Type Containing 11 2 | | C20orf1621 2 3 | | Chromosome 20 Open Reading Frame 1621 | | DJ337O18.51 | | Zinc Finger SWIM Domain-Containing Protein 12 | | Zinc Finger, SWIM Domain Containing 12 |
Export aliases for ZSWIM1 gene to outside databasesPrevious GC identifers: GC20P045195 GC20P043943 GC20P041251 |
Summaries
for ZSWIM1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ZSWIM1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011362.10
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZSWIM1 gene promoter:
TBP NF-1/L NF-1 Pax-5 Nkx2-5 Tal-1beta GATA-2 E47 PPAR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZSWIM1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZSWIM1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q13.12 Ensembl cytogenetic band: 20q13.12 HGNC chromosome: 20ZSWIM1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20P044509: view genomic region
(about GC identifiers)
Start:
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44,509,848 bp from pter |
End:
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44,513,905 bp from pter |
Size:
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4,058 bases |
Orientation:
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plus strand |
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Proteins
for ZSWIM1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZSWM1_HUMAN, Q9BR11 (See
protein sequence)Recommended Name: Zinc finger SWIM domain-containing protein 1 Size: 485 amino acids; 55071 Da
Secondary accessions: Q5JZH2 Q9BR12 Q9BV30Explore the universe of human proteins at neXtProt for ZSWIM1: NX_Q9BR11
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BR11
ZSWIM1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_542170.3
ENSEMBL proteins: ENSP00000361601 ENSP00000361598
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZSWIM1 for ontologies About GeneDecksing
ZSWIM1 Antibody Products:
Assay Products for ZSWIM1: |
Protein
Domains /
Families
for ZSWIM1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZSWIM1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9BR11ProtoNet protein and cluster: Q9BR11 UniProtKB/Swiss-Prot: ZSWM1_HUMAN, Q9BR11Similarity: Contains 1 SWIM-type zinc finger |
Function
for ZSWIM1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZSWIM1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZSWIM1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: ZSWIM1 (NM_080603) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZSWIM1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSWIM1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSWIM1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008270 | zinc ion binding |
IEA | -- |
ZSWIM1 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZSWIM1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZSWIM1
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
3 Interacting proteins for ZSWIM1 (Q9BR113 ENSP000003615984) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for ZSWIM1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZSWIM1
Search CenterWatch for drugs/clinical trials and news about ZSWIM1 / ZSWM1
|
Transcripts
for ZSWIM1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZSWIM1 gene: NM_080603.4 Unigene Cluster for ZSWIM1: Zinc finger, SWIM-type containing 1 Hs.517075 [show with all ESTs]Unigene Representative Sequence: NM_0806032 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000372523(uc010ghi.3) ENST00000372520
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZSWIM1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZSWIM1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZSWIM1 (NM_080603) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZSWIM1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSWIM1 |
Additional cDNA sequence: AK291304.1 BC001672.2 BC080525.1 8 DOTS entries: DT.95263017 DT.108877 DT.65286005 DT.120817250 DT.100780991 DT.120817428 DT.120817184 DT.75171365 24/33 AceView cDNA sequences (see all 33): BE549828 AI568593 BC080525 NM_080603 BC001672 AI356165 BU162907 BM792409 BM149047 BG328421 BX644615 BE304365 BM905849 BP383124 AI150156 AA743429 AW162601 CD694340 BQ336072 AI826551 AA054315 BE064530 AK026450 AJ574029
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ZSWIM1 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c |
|---|
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| SP1: | | | | | - | | - | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZSWIM1
|
Expression
for ZSWIM1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZSWIM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGATGACTCA
About this image
See ZSWIM1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZSWIM1
SOURCE GeneReport for Unigene cluster: Hs.517075
SABiosciences Custom PCR Arrays for ZSWIM1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZSWIM1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZSWIM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZSWIM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZSWIM1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSWIM1 |
Orthologs
for ZSWIM1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZSWIM1 gene from 2/6 species (see all 6) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Zswim11 , 5 |
zinc finger, SWIM domain containing 15
zinc finger SWIM-type containing 11 |
84.54(n)1
85.05(a)1 |
|
2 (85.27 cM)5
719711 NM_028028.21 NP_082304.11
1648226865 |
chicken
(Gallus gallus) |
Aves |
ZSWIM16 |
Uncharacterized protein |
39(a) |
1 ↔ 1 |
20(10479809-10481398) |
ENSEMBL Gene Tree for ZSWIM1 (if available)
TreeFam Gene Tree for ZSWIM1 (if available) |
Paralogs
for ZSWIM1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZSWIM1 gene
- ZSWIM32
1 SIMAP similar gene for ZSWIM1 using alignment to 1 protein entry: ZSWM1_HUMAN:ZSWIM3
ZSWIM1 for paralogs About GeneDecksing
|
Genomic Variants
for ZSWIM1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZSWIM1 (44509848 - 44513905 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZSWIM1
1 CNV: 50668 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZSWIM1 |
|
Disorders
/ Diseases
for ZSWIM1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZSWIM1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZSWIM1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZSWIM1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZSWIM1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ZSWIM1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZSWIM1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZSWIM1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZSWIM1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZSWIM1 gene:
Search GeneIP for patents involving ZSWIM1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZSWIM1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZSWIM1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZSWIM1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZSWIM1 | | | OriGene Protein Over-expression Lysate for ZSWIM1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZSWIM1 | | OriGene 3'-UTR Clone for ZSWIM1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZSWIM1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZSWIM1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ZSWIM1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZSWIM1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZSWIM1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZSWIM1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZSWIM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZSWIM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZSWIM1 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZSWIM1 |
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 | | | ZSWIM1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSWIM1 |
|  |  |  | | | | ThermoFisher Antibodies for ZSWIM1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSWIM1 |
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