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ZSCAN9 Gene

protein-coding   GIFtS: 41
GCID: GC06P028192

Zinc Finger And SCAN Domain Containing 9

(Previous name: zinc finger protein 193)
(Previous symbol: ZNF193)
  Search for ZSCAN9
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger And SCAN Domain Containing 91 2     PRD512 3
ZNF1931 2 3 5     Cell Proliferation-Inducing Protein 122
Zinc Finger Protein 1931 2 3     Zinc Finger And SCAN Domain-Containing Protein 92
Cell Proliferation-Inducing Gene 12 Protein2 3     

External Ids:    HGNC: 129841   Entrez Gene: 77462   Ensembl: ENSG000001371857   OMIM: 6022465   UniProtKB: O155353   

Export aliases for ZSCAN9 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZSCAN9 Gene:
ZSCAN9 (zinc finger and SCAN domain containing 9) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF446.

UniProtKB/Swiss-Prot: ZSC9_HUMAN, O15535
Function: May be involved in transcriptional regulation

Gene Wiki entry for ZSCAN9 (ZNF193) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_007592.16  NC_018917.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for ZSCAN9
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZSCAN9 promoter sequence
   Search Chromatin IP Primers for ZSCAN9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZSCAN9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p22.1   HGNC cytogenetic band: 6p21

ZSCAN9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZSCAN9 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P028192:  view genomic region     (about GC identifiers)

Start:
28,192,664 bp from pter      End:
28,201,265 bp from pter
Size:
8,602 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZSC9_HUMAN, O15535 (See protein sequence)
Recommended Name: Zinc finger and SCAN domain-containing protein 9  
Size: 394 amino acids; 45954 Da
Secondary accessions: B4E1W6 E7EVQ2 Q2TTR1
Alternative splicing: 2 isoforms:  O15535-1   O15535-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZSCAN9: NX_O15535

Explore proteomics data for ZSCAN9 at MOPED


See ZSCAN9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (3 alternative transcripts): 
NP_001186408.1  NP_001186409.1  NP_006290.1  

ENSEMBL proteins: 
 ENSP00000433307   ENSP00000475719   ENSP00000404074   ENSP00000252207   ENSP00000433402  
 ENSP00000433468   ENSP00000476254   ENSP00000436166  

ZSCAN9 Human Recombinant Protein Products:

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Novus Biologicals ZSCAN9 Proteins
Novus Biologicals ZSCAN9 Lysates
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Browse Proteins at Cloud-Clone Corp.

 
Search eBioscience for Proteins for ZSCAN9 

ZSCAN9 Antibody Products:

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Abcam antibodies for ZSCAN9
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LSBio Antibodies in human, mouse, rat for ZSCAN9

ZSCAN9 Assay Products:

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Search eBioscience for ELISAs for ZSCAN9 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
ZNF: Zinc fingers, C2H2-type

5 InterPro protein domains:
 IPR008916 Retrov_capsid_C
 IPR003309 Tscrpt_reg_SCAN
 IPR015880 Znf_C2H2-like
 IPR013087 Znf_C2H2/integrase_DNA-bd
 IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry O15535

ProtoNet protein and cluster: O15535

2 Blocks protein domains:
IPB003309 Transcriptional regulator SCAN
IPB007086 C2H2-type zinc finger signature


UniProtKB/Swiss-Prot: ZSC9_HUMAN, O15535
Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
Similarity: Contains 5 C2H2-type zinc fingers
Similarity: Contains 1 SCAN box domain


Find genes that share domains with ZSCAN9           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: ZSC9_HUMAN, O15535
Function: May be involved in transcriptional regulation

     Gene Ontology (GO): 4 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003676nucleic acid binding ----
GO:0003677DNA binding IEA--
GO:0003700sequence-specific DNA binding transcription factor activity IEA--
GO:0046872metal ion binding IEA--
     
Find genes that share ontologies with ZSCAN9           About GenesLikeMe


Phenotypes:
     2 GenomeRNAi human phenotypes for ZSCAN9:
 Increased cilium length after   Synthetic lethal with Ras 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZSCAN9
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZSCAN9
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZSCAN9

miRNA
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Inhib. RNA
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OriGene RNAi products in human, mouse, rat for ZSCAN9
Predesigned siRNA for gene silencing in human, mouse, rat ZSCAN9

Gene Editing
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Clone
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN9

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN9


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
ZSC9_HUMAN, O15535: Nucleus (Potential)

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--

Find genes that share ontologies with ZSCAN9           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZSCAN9
Interactions:

    Search GeneGlobe Interaction Network for ZSCAN9

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

Selected Interacting proteins for ZSCAN9 (O155352, 3 ENSP000002522074) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
InteractantInteraction Details
GeneCardExternal ID(s)
ZNF446Q9NWS93, ENSP000003365654I2D: score=3 STRING: ENSP00000336565
SP110Q9HB583, ENSP000002583814I2D: score=1 STRING: ENSP00000258381
GRB2P629933I2D: score=2 
CEP72Q9P2093I2D: score=1 
ZSCAN30ENSP000003297384STRING: ENSP00000329738
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006351transcription, DNA-templated IEA--
GO:0006355regulation of transcription, DNA-templated ----

Find genes that share ontologies with ZSCAN9           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for ZSCAN9 (ZSC9)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for ZSCAN9 gene (3 alternative transcripts): 
NM_001199479.1  NM_001199480.1  NM_006299.4  

Unigene Cluster for ZSCAN9:

Zinc finger and SCAN domain containing 9
Hs.100921  [show with all ESTs]
Unigene Representative Sequence: AY261373
8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000531941 ENST00000531981 ENST00000425468(uc010jqz.2 uc003nkr.2 uc003nkq.2)
ENST00000252207 ENST00000531979 ENST00000527436 ENST00000526391 ENST00000527844

miRNA
Products:
     
Block miRNA regulation of human, mouse, rat ZSCAN9 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate ZSCAN9
SwitchGear 3'UTR luciferase reporter plasmidZSCAN9 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for ZSCAN9
Predesigned siRNA for gene silencing in human, mouse, rat ZSCAN9
Clone
Products:
     
OriGene clones in human, mouse for ZSCAN9 (see all 7)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for ZSCAN9
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN9
Primer
Products:
    
OriGene qPCR primer pairs and template standards for ZSCAN9
OriGene qSTAR qPCR primer pairs in human, mouse for ZSCAN9
Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat ZSCAN9
  QuantiTect SYBR Green Assays in human, mouse, rat ZSCAN9
  QuantiFast Probe-based Assays in human, mouse, rat ZSCAN9

Additional mRNA sequence: 

AF024699.1 AK226035.1 AK304013.1 AY261373.1 AY550973.1 BC010374.1 U62392.1 

8 DOTS entries:

DT.312609  DT.121314837  DT.92421946  DT.100699248  DT.405873  DT.75194352  DT.101962638  DT.95275636 

Selected AceView cDNA sequences (see all 135):

BM799461 AY261373 BU677955 AI807214 CA393773 AL046723 CR619676 T11165 
BQ022785 BX434959 BM449820 BM810618 BQ955955 BI762889 CA425014 CB162959 
AU121601 BU154439 AA242984 BQ882690 BI770247 BM832880 CA425396 U62392 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN9 (see all 6)    About this scheme

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c · 3d · 3e ^ 4 ^ 5a · 5b · 5c
SP1:                    -           -                 -     -     -                     
SP2:                                -                 -     -     -                     
SP3:                    -                                                               
SP4:                                -                                                   
SP5:                                -                 -     -                           


ECgene alternative splicing isoforms for ZSCAN9

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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ZSCAN9 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
ZSCAN9 Expression
About this image

ZSCAN9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

ZSCAN9 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.100921
    Custom PCR Arrays for ZSCAN9
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QuantiFast Probe-based Assays in human, mouse, rat ZSCAN9
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN9

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN9 gene from Selected species (see all 2)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
cow
(Bos taurus)
Mammalia ZSCAN96
zinc finger and SCAN domain containing 9
78(a)
1 ↔ 1
23(30206789-30211745)


ENSEMBL Gene Tree for ZSCAN9 (if available)
TreeFam Gene Tree for ZSCAN9 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for ZSCAN9 gene
ZNF4462  ZKSCAN12  ZNF3972  ZNF5002  ZNF2132  ZNF2322  ZSCAN302  ZNF1742  
ZNF32  ZKSCAN42  ZNF3962  ZSCAN122  ZNF3942  ZSCAN212  ZSCAN232  ZNF1652  
ZSCAN162  ZKSCAN82  ZSCAN222  ZSCAN312  ZNF242  ZKSCAN32  ZNF182  
Selected SIMAP similar genes for ZSCAN9 using alignment to 5 protein entries:     ZSC9_HUMAN (see all proteins) (see all similar genes):
ZNF154    ZFP3    ZNF818P    ZNF3    LOC100128510    ZNF211
HZF36    RREB1    SCAND1    ZNF416    ZNF470    ZNF519
ZNF585B    ZNF78L1    ZNF792    ZNF813    ZNF585A    ZNF620

Find genes that share paralogs with ZSCAN9           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for ZSCAN9 (see all 246)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 6 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs93667171,2
C,F,H--28191057(+) TTTAGC/TTTATG 3 -- us2k1 tfbs321Minor allele frequency- N:0.00NS EA NA WA 2552
rs1461471051,2
--28191064(+) TATGGC/TATAAC 3 -- us2k10--------
rs1826388921,2
--28191077(+) ACAGCC/TGAGTT 3 -- us2k10--------
rs1876469181,2
--28191100(+) TGCCTC/GCTTCT 3 -- us2k10--------
rs1925215241,2
--28191161(+) TTGTCG/TTTGAG 3 -- us2k10--------
rs1828454691,2
--28191194(+) CAGTAC/TGGATT 3 -- us2k10--------
rs356569321,2
C,F--28191288(+) CAAATG/TAAAGC 3 -- us2k14Minor allele frequency- T:0.13NA 126
rs1875228081,2
--28191334(+) CGTGCA/TGCCCA 3 -- us2k10--------
rs760711721,2
C,F--28191336(+) TGCTGC/TCCACT 3 -- us2k12Minor allele frequency- T:0.09CSA WA 120
rs1926297141,2
--28191567(+) TTTCAC/TAGTTT 3 -- us2k10--------

HapMap Linkage Disequilibrium report for ZSCAN9 (28192664 - 28201265 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for ZSCAN9: --
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing ZSCAN9
DNA2.0 Custom Variant and Variant Library Synthesis for ZSCAN9

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 602246    OMIM disorders: --


Find genes that share disorders with ZSCAN9           About GenesLikeMe


Export disorders for ZSCAN9 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for ZSCAN9 gene integrated from 10 sources:
(articles sorted by number of sources associating them with ZSCAN9)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  2. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
  3. Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. (PubMed id 9244436)1, 2 Lee P.L.... Beutler E. (Genomics 1997)
  4. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
  5. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (Cell 2010)
  6. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (Nature 2005)
  7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  9. The zinc finger-associated SCAN box is a conserved oligomerization domain. (PubMed id 10567577)1 Williams A.J....Collins T. (Mol. Cell. Biol. 1999)
  10. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (Gene 1994)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 7746 HGNC: 12984 AceView: ZNF193 Ensembl:ENSG00000137185 euGenes: HUgn7746
ECgene: ZSCAN9 H-InvDB: ZSCAN9

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for ZSCAN9 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for ZSCAN9 gene:
Search GeneIP for patents involving ZSCAN9

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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