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Aliases for ZSCAN5B Gene

Aliases for ZSCAN5B Gene

  • Zinc Finger And SCAN Domain Containing 5B 2 3 5
  • ZNF495B 3
  • ZNF371 3

External Ids for ZSCAN5B Gene

Previous GeneCards Identifiers for ZSCAN5B Gene

  • GC19M061397
  • GC19M056701
  • GC19M053010

Summaries for ZSCAN5B Gene

GeneCards Summary for ZSCAN5B Gene

ZSCAN5B (Zinc Finger And SCAN Domain Containing 5B) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZSCAN5CP.

UniProtKB/Swiss-Prot for ZSCAN5B Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN5B Gene

Genomics for ZSCAN5B Gene

Regulatory Elements for ZSCAN5B Gene


Genomic Location for ZSCAN5B Gene

Chromosome:
19
Start:
56,189,570 bp from pter
End:
56,208,038 bp from pter
Size:
18,469 bases
Orientation:
Minus strand

Genomic View for ZSCAN5B Gene

Genes around ZSCAN5B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN5B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN5B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN5B Gene

Proteins for ZSCAN5B Gene

  • Protein details for ZSCAN5B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NJL1-ZSA5B_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 5B
    Protein Accession:
    A6NJL1

    Protein attributes for ZSCAN5B Gene

    Size:
    495 amino acids
    Molecular mass:
    55826 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZSCAN5B Gene

Proteomics data for ZSCAN5B Gene at MOPED

Post-translational modifications for ZSCAN5B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZSCAN5B Gene

No data available for DME Specific Peptides for ZSCAN5B Gene

Domains & Families for ZSCAN5B Gene

Gene Families for ZSCAN5B Gene

Protein Domains for ZSCAN5B Gene

Suggested Antigen Peptide Sequences for ZSCAN5B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NJL1

UniProtKB/Swiss-Prot:

ZSA5B_HUMAN :
  • Contains 1 SCAN box domain.
  • Contains 5 C2H2-type zinc fingers.
Domain:
  • Contains 1 SCAN box domain.
Similarity:
  • Contains 5 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZSCAN5B: view

Function for ZSCAN5B Gene

Molecular function for ZSCAN5B Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZSCAN5B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA --
genes like me logo Genes that share ontologies with ZSCAN5B: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZSCAN5B Gene

Localization for ZSCAN5B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN5B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZSCAN5B Gene COMPARTMENTS Subcellular localization image for ZSCAN5B gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZSCAN5B Gene

Pathways & Interactions for ZSCAN5B Gene

SuperPathways for ZSCAN5B Gene

No Data Available

Interacting Proteins for ZSCAN5B Gene

Gene Ontology (GO) - Biological Process for ZSCAN5B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZSCAN5B: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN5B Gene

Drugs & Compounds for ZSCAN5B Gene

No Compound Related Data Available

Transcripts for ZSCAN5B Gene

Unigene Clusters for ZSCAN5B Gene

Zinc finger and SCAN domain containing 5B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN5B Gene

No ASD Table

Relevant External Links for ZSCAN5B Gene

GeneLoc Exon Structure for
ZSCAN5B
ECgene alternative splicing isoforms for
ZSCAN5B

Expression for ZSCAN5B Gene

mRNA expression in normal human tissues for ZSCAN5B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZSCAN5B Gene

This gene is overexpressed in Testis (x19.1).

SOURCE GeneReport for Unigene cluster for ZSCAN5B Gene Hs.132130

genes like me logo Genes that share expression patterns with ZSCAN5B: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZSCAN5B Gene

Orthologs for ZSCAN5B Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN5B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC790324 35
  • 72.55 (n)
  • 64.71 (a)
-- 36
  • 47 (a)
ManyToMany
-- 36
  • 49 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
-- 36
  • 47 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 42 (a)
ManyToMany
-- 36
  • 44 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zscan5b 35
  • 58.94 (n)
  • 47.54 (a)
Zscan5b 16
Zscan5b 36
  • 44 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia ZSCAN5B 35
  • 97.91 (n)
  • 95.35 (a)
ZSCAN5B 36
  • 95 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zscan5b 35
  • 58.37 (n)
  • 45.78 (a)
Species with no ortholog for ZSCAN5B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN5B Gene

ENSEMBL:
Gene Tree for ZSCAN5B (if available)
TreeFam:
Gene Tree for ZSCAN5B (if available)

Paralogs for ZSCAN5B Gene

Paralogs for ZSCAN5B Gene

Pseudogenes.org Pseudogenes for ZSCAN5B Gene

genes like me logo Genes that share paralogs with ZSCAN5B: view

Variants for ZSCAN5B Gene

Sequence variations from dbSNP and Humsavar for ZSCAN5B Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs527025 - 56,191,879(+) CCTGG(A/G)CAGGA intron-variant, reference, missense
rs4801296 - 56,190,954(+) TGTTA(C/G/T)GTCAA reference, missense
rs10425951 - 56,190,870(+) GGATG(A/T)CAGTC reference, missense
rs892183 - 56,190,405(+) GGAGG(A/T)GGCAT reference, missense
rs16987048 - 56,190,081(+) ACACA(G/T)GTAGG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN5B Gene

Variant ID Type Subtype PubMed ID
dgv206n21 CNV Loss 19592680
nsv912516 CNV Gain 21882294
esv2663363 CNV Deletion 23128226
nsv828646 CNV Loss 20364138
nsv828647 CNV Loss 20364138
esv5726 OTHER Inversion 19470904

Variation tolerance for ZSCAN5B Gene

Residual Variation Intolerance Score: 93.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.12; 80.59% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZSCAN5B Gene

Disorders for ZSCAN5B Gene

Relevant External Links for ZSCAN5B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZSCAN5B

No disorders were found for ZSCAN5B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN5B Gene

Publications for ZSCAN5B Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4 67
  2. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3

Products for ZSCAN5B Gene

Sources for ZSCAN5B Gene

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