ZSCAN5A Gene
protein-coding GIFtS: 43
GCID: GC19M056732
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|
zinc finger and SCAN domain containing 5A(Previous names: zinc finger protein 495, zinc finger and SCAN domain containing...)
(Previous symbols: ZNF495, ZSCAN5)
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Aliases
for ZSCAN5A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger And SCAN Domain Containing 5A1 2 | | Zinc Finger And SCAN Domain Containing 51 2 | | Zinc Finger Protein 4951 2 3 | | MGC41611 | | ZNF4951 2 3 | | Zinc Finger And SCAN Domain-Containing Protein 5A2 | | ZSCAN51 2 3 | | |
Export aliases for ZSCAN5A gene to outside databasesPrevious GC identifers: GC19M061426 GC19M053042 |
Summaries
for ZSCAN5A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZSA5A_HUMAN, Q9BUG6Function: May be involved in transcriptional regulation
|
Genomic Views
for ZSCAN5A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZSCAN5A gene promoter:
AREB6 POU2F1 POU2F1a CUTL1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZSCAN5A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZSCAN5A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.43 Ensembl cytogenetic band: 19q13.43 HGNC cytogenetic band: 19q13.43ZSCAN5A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M056732: view genomic region
(about GC identifiers)
Start:
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56,732,679 bp from pter |
End:
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56,879,752 bp from pter |
Size:
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147,074 bases |
Orientation:
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minus strand |
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Proteins
for ZSCAN5A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZSA5A_HUMAN, Q9BUG6 (See
protein sequence)Recommended Name: Zinc finger and SCAN domain-containing protein 5A Size: 496 amino acids; 55865 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: Q49A73 Q53F04 Q8N7B3Explore the universe of human proteins at neXtProt for ZSCAN5A: NX_Q9BUG6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BUG6
ZSCAN5A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_077279.1
ENSEMBL proteins: ENSP00000375593 ENSP00000467238 ENSP00000467631 ENSP00000466445 ENSP00000464936 ENSP00000468797 ENSP00000468008 ENSP00000468675 ENSP00000466830 ENSP00000254165
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZSCAN5A for ontologies About GeneDecksing
ZSCAN5A Antibody Products:
Assay Products for ZSCAN5A: |
Protein
Domains /
Families
for ZSCAN5A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZSCAN5A for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9BUG6ProtoNet protein and cluster: Q9BUG6 1 Blocks protein family: IPB003309 Transcriptional regulator SCAN
UniProtKB/Swiss-Prot: ZSA5A_HUMAN, Q9BUG6Similarity: Contains 5 C2H2-type zinc fingersSimilarity: Contains 1 SCAN box domain |
Function
for ZSCAN5A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZSA5A_HUMAN, Q9BUG6Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN5A
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN5A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZSCAN5A (NM_024303) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZSCAN5A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN5A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN5A |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
IEA | -- | | GO:0003700 | sequence-specific DNA binding transcription factor activity |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
ZSCAN5A for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for ZSCAN5A:
|
Pathways & Interactions
for ZSCAN5A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZSCAN5A
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0016032 | viral reproduction |
IEA | -- |
ZSCAN5A for ontologies About GeneDecksing
|
Drugs & Compounds
for ZSCAN5A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZSCAN5A
Search CenterWatch for drugs/clinical trials and news about ZSCAN5A / ZSA5A
|
Transcripts
for ZSCAN5A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZSCAN5A gene: NM_024303.1 Unigene Cluster for ZSCAN5A: Zinc finger and SCAN domain containing 5A Hs.177688 [show with all ESTs]Unigene Representative Sequence: BC04323218 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000391713(uc002qmq.3 uc002qmr.3 uc002qms.1) ENST00000592355
ENST00000587340 ENST00000587492 ENST00000593106 ENST00000592101 ENST00000592509
ENST00000588955 ENST00000588442 ENST00000592679 ENST00000590675 ENST00000586031
ENST00000591078 ENST00000589279 ENST00000585670 ENST00000587075 ENST00000587614
ENST00000254165(uc010ygi.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN5A
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN5A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZSCAN5A (NM_024303) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZSCAN5A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN5A |
Additional cDNA sequence: AK098700.1 AK223485.1 AK301873.1 AK310500.1 BC002636.1 BC043232.1 9 DOTS entries: DT.407669 DT.100770533 DT.100770535 DT.92420440 DT.210582 DT.97840260 DT.97774941 DT.121490855 DT.121491014 24/47 AceView cDNA sequences (see all 47): BC002636 BI829761 BM563481 BQ024588 AK098700 NM_024303 BE391420 BU535566 CA310351 AW614347 BP371211 R27198 BG055866 AI699820 BU616538 BI520206 BU753182 AA961935 BX366910 BE463585 BM556563 AI201290 BX366909 BI560465
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN5A About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b |
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| SP1: | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | | | |
| SP5: | | | - | | - | | - | | - | | | | | | | | | |
ECgene alternative splicing isoforms for ZSCAN5A
|
Expression
for ZSCAN5A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZSCAN5A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAAGGGCGTC
About this image
See ZSCAN5A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZSCAN5A
SOURCE GeneReport for Unigene cluster: Hs.177688
SABiosciences Custom PCR Arrays for ZSCAN5A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZSCAN5A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZSCAN5A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZSCAN5A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZSCAN5A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN5A |
Orthologs
for ZSCAN5A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZSCAN5A gene from 2/8 species (see all 8) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
BX324198.26 |
-- |
17(a) |
1 → many |
7(19676949-19685583) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Cf26Kr6 |
Kruppel |
17(a)15(a) |
possible ortholog1 ↔ many |
2L(4876890-4883341) 2R(21114134-21118917) |
ENSEMBL Gene Tree for ZSCAN5A (if available)
TreeFam Gene Tree for ZSCAN5A (if available) |
Paralogs
for ZSCAN5A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZSCAN5A gene
- ZSCAN5C2 ZSCAN5B2
18/184 SIMAP similar genes for ZSCAN5A using alignment to 8 protein entries: ZSA5A_HUMAN (see all proteins)
(see all similar genes):ZSCAN5C ZSCAN5B ZSCAN5D kr-znf3 ZNF782 ZSCAN23
DKFZp666M039 ZNF26 ZNF391 ZNF394 LOC100128510 ZNF78L1
ZNF678 ZSCAN10 ZFP112 ZNF135 ZNF28 ZNF286B
ZSCAN5A for paralogs About GeneDecksing
|
Genomic Variants
for ZSCAN5A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZSCAN5A (56732679 - 56879752 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZSCAN5A
1 CNV: 61727
1 Inversion: 59752 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZSCAN5A |
|
Disorders
/ Diseases
for ZSCAN5A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZSCAN5A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZSCAN5A gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZSCAN5A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZSCAN5A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZSCAN5A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZSCAN5A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZSCAN5A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZSCAN5A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZSCAN5A gene:
Search GeneIP for patents involving ZSCAN5A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZSCAN5A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZSCAN5A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZSCAN5A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZSCAN5A | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZSCAN5A | | OriGene 3'-UTR Clone for ZSCAN5A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN5A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN5A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZSCAN5A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZSCAN5A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZSCAN5A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZSCAN5A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZSCAN5A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZSCAN5A |
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 |  |  |  | |
| | | | Search Tocris compounds for ZSCAN5A |
| |  |  |  |  | | | | |
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 | | | ZSCAN5A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN5A |
|  |  |  | | | | Search ThermoFisher Antibodies for ZSCAN5A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN5A |
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