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Aliases for ZSCAN5A Gene

Aliases for ZSCAN5A Gene

  • Zinc Finger And SCAN Domain Containing 5A 2 3
  • Zinc Finger Protein 495 2 3 4
  • Zinc Finger And SCAN Domain Containing 5 2 3
  • ZNF495 3 4
  • ZSCAN5 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 5A 3

External Ids for ZSCAN5A Gene

Previous HGNC Symbols for ZSCAN5A Gene

  • ZNF495
  • ZSCAN5

Previous GeneCards Identifiers for ZSCAN5A Gene

  • GC19M061426
  • GC19M056732
  • GC19M053042

Summaries for ZSCAN5A Gene

GeneCards Summary for ZSCAN5A Gene

ZSCAN5A (Zinc Finger And SCAN Domain Containing 5A) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding RNA polymerase II transcription factor activity. An important paralog of this gene is ZSCAN5C.

UniProtKB/Swiss-Prot for ZSCAN5A Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN5A Gene

Genomics for ZSCAN5A Gene

Regulatory Elements for ZSCAN5A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZSCAN5A Gene

Start:
56,219,670 bp from pter
End:
56,368,383 bp from pter
Size:
148,714 bases
Orientation:
Minus strand

Genomic View for ZSCAN5A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZSCAN5A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN5A Gene

Proteins for ZSCAN5A Gene

  • Protein details for ZSCAN5A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BUG6-ZSA5A_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 5A
    Protein Accession:
    Q9BUG6
    Secondary Accessions:
    • B4DX98
    • Q49A73
    • Q53F04
    • Q8N7B3

    Protein attributes for ZSCAN5A Gene

    Size:
    496 amino acids
    Molecular mass:
    55865 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZSCAN5A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSCAN5A Gene

Proteomics data for ZSCAN5A Gene at MOPED

Post-translational modifications for ZSCAN5A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZSCAN5A Gene

Domains for ZSCAN5A Gene

Gene Families for ZSCAN5A Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZSCAN5A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BUG6

UniProtKB/Swiss-Prot:

ZSA5A_HUMAN :
  • Q9BUG6
Domain:
  • Contains 1 SCAN box domain.
Similarity:
  • Contains 5 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZSCAN5A: view

Function for ZSCAN5A Gene

Molecular function for ZSCAN5A Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZSCAN5A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity IBA --
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN5A: view

Phenotypes for ZSCAN5A Gene

GenomeRNAi human phenotypes for ZSCAN5A:
genes like me logo Genes that share phenotypes with ZSCAN5A: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZSCAN5A Gene

Localization for ZSCAN5A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN5A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZSCAN5A Gene COMPARTMENTS Subcellular localization image for ZSCAN5A gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZSCAN5A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZSCAN5A: view

Pathways for ZSCAN5A Gene

SuperPathways for ZSCAN5A Gene

No Data Available

Interacting Proteins for ZSCAN5A Gene

Gene Ontology (GO) - Biological Process for ZSCAN5A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated --
GO:0006355 regulation of transcription, DNA-templated --
GO:0006357 regulation of transcription from RNA polymerase II promoter IBA --
GO:0006366 transcription from RNA polymerase II promoter IBA --
genes like me logo Genes that share ontologies with ZSCAN5A: view

No data available for Pathways by source for ZSCAN5A Gene

Transcripts for ZSCAN5A Gene

Unigene Clusters for ZSCAN5A Gene

Zinc finger and SCAN domain containing 5A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZSCAN5A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN5A Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5a · 5b
SP1:
SP2: -
SP3:
SP4: -
SP5: - - - -

Relevant External Links for ZSCAN5A Gene

GeneLoc Exon Structure for
ZSCAN5A
ECgene alternative splicing isoforms for
ZSCAN5A

Expression for ZSCAN5A Gene

mRNA expression in normal human tissues for ZSCAN5A Gene

mRNA differential expression in normal tissues according to GTEx for ZSCAN5A Gene

This gene is overexpressed in Testis (7.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZSCAN5A Gene

SOURCE GeneReport for Unigene cluster for ZSCAN5A Gene Hs.177688

genes like me logo Genes that share expressions with ZSCAN5A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZSCAN5A Gene

Orthologs for ZSCAN5A Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN5A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZSCAN5A 35
  • 99.53 (n)
  • 98.99 (a)
ZSCAN5A 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 44 (a)
ManyToMany
-- 36
  • 46 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
-- 36
  • 40 (a)
ManyToMany
-- 36
  • 40 (a)
ManyToMany
-- 36
  • 41 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
-- 36
  • 40 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zscan5b 36
  • 37 (a)
OneToMany
Species with no ortholog for ZSCAN5A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN5A Gene

ENSEMBL:
Gene Tree for ZSCAN5A (if available)
TreeFam:
Gene Tree for ZSCAN5A (if available)

Paralogs for ZSCAN5A Gene

Paralogs for ZSCAN5A Gene

Selected SIMAP similar genes for ZSCAN5A Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with ZSCAN5A: view

Variants for ZSCAN5A Gene

Sequence variations from dbSNP and Humsavar for ZSCAN5A Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1972785 -- 56,223,038(+) CTGAC(A/G)CTGGA intron-variant
rs2011848 -- 56,223,109(+) ACCCT(C/G)CTGGA intron-variant
rs2195974 -- 56,231,728(+) ttagc(A/G)gcatt upstream-variant-2KB
rs2195975 -- 56,231,771(+) ctagc(A/T)ggttc upstream-variant-2KB
rs2217668 -- 56,231,911(+) CCACA(A/G)CTCCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN5A Gene

Variant ID Type Subtype PubMed ID
nsv912516 CNV Gain 21882294
nsv828646 CNV Loss 20364138
nsv828647 CNV Loss 20364138
esv5726 OTHER Inversion 19470904
esv2719027 CNV Deletion 23290073
esv7336 CNV Loss 19470904

Relevant External Links for ZSCAN5A Gene

HapMap Linkage Disequilibrium report
ZSCAN5A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSCAN5A Gene

Disorders for ZSCAN5A Gene

No disorders were found for ZSCAN5A Gene.

No data available for UniProtKB/Swiss-Prot for ZSCAN5A Gene

Publications for ZSCAN5A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4
  5. The consensus coding sequences of human breast and colorectal cancers. (PMID: 16959974) Sjoeblom T. … Velculescu V.E. (Science 2006) 4

Products for ZSCAN5A Gene

Sources for ZSCAN5A Gene

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