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Aliases for ZSCAN5A Gene

Aliases for ZSCAN5A Gene

  • Zinc Finger And SCAN Domain Containing 5A 2 3 5
  • Zinc Finger Protein 495 2 3 4
  • Zinc Finger And SCAN Domain Containing 5 2 3
  • ZNF495 3 4
  • ZSCAN5 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 5A 3

External Ids for ZSCAN5A Gene

Previous HGNC Symbols for ZSCAN5A Gene

  • ZNF495
  • ZSCAN5

Previous GeneCards Identifiers for ZSCAN5A Gene

  • GC19M061426
  • GC19M056732
  • GC19M053042

Summaries for ZSCAN5A Gene

GeneCards Summary for ZSCAN5A Gene

ZSCAN5A (Zinc Finger And SCAN Domain Containing 5A) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZSCAN5C.

UniProtKB/Swiss-Prot for ZSCAN5A Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN5A Gene

Genomics for ZSCAN5A Gene

Regulatory Elements for ZSCAN5A Gene

Enhancers for ZSCAN5A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G056324 0.8 FANTOM5 ENCODE 4.2 +43.6 43612 0.5 PAF1 RBFOX2 ZNF444 ZSCAN5A LOC729999 PIR48946
GH19G056293 0.8 FANTOM5 ENCODE 4.1 +73.1 73085 2.7 NFIC ZNF316 NFIB MAFK ZBTB40 NLRP5 ZSCAN5A NLRP11 NLRP8 ZNF583 NLRP13 LOC105372470 ENSG00000267298
GH19G056089 1.6 FANTOM5 Ensembl ENCODE dbSUPER 2 +276.8 276793 3.4 PKNOX1 CBX3 NFIB KLF17 SIN3A FEZF1 BRCA1 RFX5 RCOR1 FOS NLRP5 NLRP11 ZSCAN5A NLRP8 ENSG00000223060 LINC01864
GH19G056321 1.8 FANTOM5 Ensembl ENCODE dbSUPER 1.7 +46.3 46279 1.4 ATF1 NFRKB RARA TCF12 ZNF766 GATA2 CREM PAF1 SMAD5 ZBTB11 ZSCAN5A LOC729999 VN2R17P
GH19G056614 0.3 FANTOM5 5.3 -245.9 -245947 0.1 ZNF470 ZSCAN5A ZNF583 ZNF71 PEG3 ZNF667 ENSG00000268036 SMIM17
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZSCAN5A on UCSC Golden Path with GeneCards custom track

Genomic Location for ZSCAN5A Gene

Chromosome:
19
Start:
56,219,670 bp from pter
End:
56,368,383 bp from pter
Size:
148,714 bases
Orientation:
Minus strand

Genomic View for ZSCAN5A Gene

Genes around ZSCAN5A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN5A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN5A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN5A Gene

Proteins for ZSCAN5A Gene

  • Protein details for ZSCAN5A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BUG6-ZSA5A_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 5A
    Protein Accession:
    Q9BUG6
    Secondary Accessions:
    • B4DX98
    • Q49A73
    • Q53F04
    • Q8N7B3

    Protein attributes for ZSCAN5A Gene

    Size:
    496 amino acids
    Molecular mass:
    55865 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZSCAN5A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSCAN5A Gene

Post-translational modifications for ZSCAN5A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZSCAN5A Gene

Domains & Families for ZSCAN5A Gene

Gene Families for ZSCAN5A Gene

Suggested Antigen Peptide Sequences for ZSCAN5A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZSCAN5A: view

No data available for UniProtKB/Swiss-Prot for ZSCAN5A Gene

Function for ZSCAN5A Gene

Molecular function for ZSCAN5A Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZSCAN5A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN5A: view
genes like me logo Genes that share phenotypes with ZSCAN5A: view

Animal Model Products

CRISPR Products

miRNA for ZSCAN5A Gene

miRTarBase miRNAs that target ZSCAN5A

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZSCAN5A Gene

Localization for ZSCAN5A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN5A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZSCAN5A gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZSCAN5A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA,IEA --
genes like me logo Genes that share ontologies with ZSCAN5A: view

Pathways & Interactions for ZSCAN5A Gene

SuperPathways for ZSCAN5A Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZSCAN5A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription from RNA polymerase II promoter IEA --
genes like me logo Genes that share ontologies with ZSCAN5A: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN5A Gene

Drugs & Compounds for ZSCAN5A Gene

No Compound Related Data Available

Transcripts for ZSCAN5A Gene

Unigene Clusters for ZSCAN5A Gene

Zinc finger and SCAN domain containing 5A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN5A Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5a · 5b
SP1:
SP2: -
SP3:
SP4: -
SP5: - - - -

Relevant External Links for ZSCAN5A Gene

GeneLoc Exon Structure for
ZSCAN5A
ECgene alternative splicing isoforms for
ZSCAN5A

Expression for ZSCAN5A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZSCAN5A Gene

mRNA differential expression in normal tissues according to GTEx for ZSCAN5A Gene

This gene is overexpressed in Testis (x7.5).

Protein differential expression in normal tissues from HIPED for ZSCAN5A Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZSCAN5A Gene



Protein tissue co-expression partners for ZSCAN5A Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZSCAN5A Gene:

ZSCAN5A

SOURCE GeneReport for Unigene cluster for ZSCAN5A Gene:

Hs.177688
genes like me logo Genes that share expression patterns with ZSCAN5A: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZSCAN5A Gene

Orthologs for ZSCAN5A Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN5A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZSCAN5A 34 35
  • 99.53 (n)
cow
(Bos Taurus)
Mammalia -- 35
  • 46 (a)
ManyToMany
-- 35
  • 44 (a)
ManyToMany
-- 35
  • 41 (a)
ManyToMany
-- 35
  • 40 (a)
ManyToMany
-- 35
  • 40 (a)
ManyToMany
-- 35
  • 40 (a)
ManyToMany
-- 35
  • 39 (a)
ManyToMany
-- 35
  • 39 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zscan5b 35
  • 37 (a)
OneToMany
Species where no ortholog for ZSCAN5A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN5A Gene

ENSEMBL:
Gene Tree for ZSCAN5A (if available)
TreeFam:
Gene Tree for ZSCAN5A (if available)

Paralogs for ZSCAN5A Gene

Paralogs for ZSCAN5A Gene

(190) SIMAP similar genes for ZSCAN5A Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with ZSCAN5A: view

Variants for ZSCAN5A Gene

Sequence variations from dbSNP and Humsavar for ZSCAN5A Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs145011101 A colorectal cancer sample 56,223,783(+) CATCT(C/G/T)GATAT reference, missense
rs1000019743 -- 56,302,105(+) GAAGA(A/C)GGCAG intron-variant
rs1000031411 -- 56,253,687(+) GAGAC(A/G)TTATC intron-variant
rs1000046315 -- 56,259,761(+) TTGAG(C/T)TCAGG intron-variant
rs1000055361 -- 56,255,462(+) CCAAC(C/T)TGCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN5A Gene

Variant ID Type Subtype PubMed ID
dgv3681n100 CNV gain 25217958
dgv3683n100 CNV gain 25217958
dgv6583n54 CNV loss 21841781
esv2719027 CNV deletion 23290073
esv5726 OTHER inversion 19470904
esv7336 CNV loss 19470904
nsv828646 CNV loss 20364138
nsv828647 CNV loss 20364138
nsv978856 CNV duplication 23825009

Variation tolerance for ZSCAN5A Gene

Residual Variation Intolerance Score: 82.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.82; 67.07% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZSCAN5A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZSCAN5A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSCAN5A Gene

Disorders for ZSCAN5A Gene

Relevant External Links for ZSCAN5A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZSCAN5A

No disorders were found for ZSCAN5A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN5A Gene

Publications for ZSCAN5A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. The consensus coding sequences of human breast and colorectal cancers. (PMID: 16959974) Sjoeblom T. … Velculescu V.E. (Science 2006) 4 64

Products for ZSCAN5A Gene

Sources for ZSCAN5A Gene

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