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Aliases for ZSCAN32 Gene

Aliases for ZSCAN32 Gene

  • Zinc Finger And SCAN Domain Containing 32 2 3
  • Zinc Finger Protein 434 2 3 4
  • Human Cervical Cancer Suppressor Gene 5 Protein 3 4
  • ZNF434 3 4
  • HCCS-5 3 4

External Ids for ZSCAN32 Gene

Previous HGNC Symbols for ZSCAN32 Gene

  • ZNF434

Previous GeneCards Identifiers for ZSCAN32 Gene

  • GC16M003457
  • GC16M003462
  • GC16M003466

Summaries for ZSCAN32 Gene

GeneCards Summary for ZSCAN32 Gene

ZSCAN32 (Zinc Finger And SCAN Domain Containing 32) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZKSCAN2.

UniProtKB/Swiss-Prot for ZSCAN32 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN32 Gene

Genomics for ZSCAN32 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZSCAN32 Gene

Chromosome:
16
Start:
3,382,081 bp from pter
End:
3,401,065 bp from pter
Size:
18,985 bases
Orientation:
Minus strand

Genomic View for ZSCAN32 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZSCAN32 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN32 Gene

No data available for Regulatory Elements for ZSCAN32 Gene

Proteins for ZSCAN32 Gene

  • Protein details for ZSCAN32 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NX65-ZSC32_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 32
    Protein Accession:
    Q9NX65
    Secondary Accessions:
    • B4DWL5
    • C9JB03
    • Q6WMU8
    • Q7Z6G2
    • Q8NFX8
    • Q9BU74

    Protein attributes for ZSCAN32 Gene

    Size:
    697 amino acids
    Molecular mass:
    78728 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH02859.1; Type=Frameshift; Positions=254; Evidence={ECO:0000305}; Sequence=AAH02859.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence starting in position 426.; Evidence={ECO:0000305}; Sequence=AAM73658.1; Type=Miscellaneous discrepancy; Note=The cDNA sequence has been translated in the reverse direction.; Evidence={ECO:0000305}; Sequence=BAA91155.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZSCAN32 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSCAN32 Gene

Proteomics data for ZSCAN32 Gene at MOPED

Post-translational modifications for ZSCAN32 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for ZSCAN32 Gene

Domains & Families for ZSCAN32 Gene

Gene Families for ZSCAN32 Gene

Protein Domains for ZSCAN32 Gene

Graphical View of Domain Structure for InterPro Entry

Q9NX65

UniProtKB/Swiss-Prot:

ZSC32_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 6 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
  • Contains 1 SCAN box domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 6 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZSCAN32: view

Function for ZSCAN32 Gene

Molecular function for ZSCAN32 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZSCAN32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding --
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with ZSCAN32: view
genes like me logo Genes that share phenotypes with ZSCAN32: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZSCAN32

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZSCAN32 Gene

Localization for ZSCAN32 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN32 Gene

Gene Ontology (GO) - Cellular Components for ZSCAN32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZSCAN32: view

No data available for Subcellular locations from COMPARTMENTS for ZSCAN32 Gene

Pathways & Interactions for ZSCAN32 Gene

SuperPathways for ZSCAN32 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZSCAN32: view

Pathways by source for ZSCAN32 Gene

2 Reactome pathways for ZSCAN32 Gene

Gene Ontology (GO) - Biological Process for ZSCAN32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated --
GO:0006357 regulation of transcription from RNA polymerase II promoter IBA --
genes like me logo Genes that share ontologies with ZSCAN32: view

No data available for SIGNOR curated interactions for ZSCAN32 Gene

Drugs & Compounds for ZSCAN32 Gene

No Compound Related Data Available

Transcripts for ZSCAN32 Gene

Unigene Clusters for ZSCAN32 Gene

Zinc finger and SCAN domain containing 32:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZSCAN32

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN32 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d
SP1:
SP2: -
SP3: -
SP4:
SP5: - - - -
SP6: - - -
SP7: - - - - - -

Relevant External Links for ZSCAN32 Gene

GeneLoc Exon Structure for
ZSCAN32
ECgene alternative splicing isoforms for
ZSCAN32

Expression for ZSCAN32 Gene

mRNA expression in normal human tissues for ZSCAN32 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZSCAN32 Gene



SOURCE GeneReport for Unigene cluster for ZSCAN32 Gene Hs.592078

genes like me logo Genes that share expression patterns with ZSCAN32: view

Protein tissue co-expression partners for ZSCAN32 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZSCAN32 Gene

Orthologs for ZSCAN32 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN32 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF434 35
  • 99.33 (n)
  • 98.71 (a)
ZSCAN32 36
  • 69 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 14 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 22 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia ZSCAN32 36
  • 24 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm9772 36
  • 44 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 17 (a)
OneToMany
-- 36
  • 27 (a)
OneToMany
Species with no ortholog for ZSCAN32:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN32 Gene

ENSEMBL:
Gene Tree for ZSCAN32 (if available)
TreeFam:
Gene Tree for ZSCAN32 (if available)

Paralogs for ZSCAN32 Gene

Paralogs for ZSCAN32 Gene

(331) SIMAP similar genes for ZSCAN32 Gene using alignment to 10 proteins:

genes like me logo Genes that share paralogs with ZSCAN32: view

Variants for ZSCAN32 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN32 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
VAR_024215 -
VAR_052826 -

Variation tolerance for ZSCAN32 Gene

Residual Variation Intolerance Score: 75.74% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.19; 80.90% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZSCAN32 Gene

HapMap Linkage Disequilibrium report
ZSCAN32

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZSCAN32 Gene

Disorders for ZSCAN32 Gene

Relevant External Links for ZSCAN32

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZSCAN32
genes like me logo Genes that share disorders with ZSCAN32: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN32 Gene

Publications for ZSCAN32 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 67
  4. An atlas of combinatorial transcriptional regulation in mouse and man. (PMID: 20211142) Ravasi T. … Hayashizaki Y. (Cell 2010) 67
  5. An empirical framework for binary interactome mapping. (PMID: 19060904) Venkatesan K. … Vidal M. (Nat. Methods 2009) 67

Products for ZSCAN32 Gene

Sources for ZSCAN32 Gene

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