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Aliases for ZSCAN32 Gene

Aliases for ZSCAN32 Gene

  • Zinc Finger And SCAN Domain Containing 32 2 3
  • Zinc Finger Protein 434 2 3 4
  • Human Cervical Cancer Suppressor Gene 5 Protein 3 4
  • ZNF434 3 4
  • HCCS-5 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 32 3

External Ids for ZSCAN32 Gene

Previous HGNC Symbols for ZSCAN32 Gene

  • ZNF434

Previous GeneCards Identifiers for ZSCAN32 Gene

  • GC16M003457
  • GC16M003462
  • GC16M003466

Summaries for ZSCAN32 Gene

GeneCards Summary for ZSCAN32 Gene

ZSCAN32 (Zinc Finger And SCAN Domain Containing 32) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding RNA polymerase II transcription factor activity. An important paralog of this gene is ZKSCAN2.

UniProtKB/Swiss-Prot for ZSCAN32 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN32 Gene

Genomics for ZSCAN32 Gene

Genomic Location for ZSCAN32 Gene

Start:
3,381,661 bp from pter
End:
3,401,065 bp from pter
Size:
19,405 bases
Orientation:
Minus strand

Genomic View for ZSCAN32 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZSCAN32 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN32 Gene

No data available for Regulatory Elements for ZSCAN32 Gene

Proteins for ZSCAN32 Gene

  • Protein details for ZSCAN32 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NX65-ZSC32_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 32
    Protein Accession:
    Q9NX65
    Secondary Accessions:
    • B4DWL5
    • C9JB03
    • Q6WMU8
    • Q7Z6G2
    • Q8NFX8
    • Q9BU74

    Protein attributes for ZSCAN32 Gene

    Size:
    697 amino acids
    Molecular mass:
    78728 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH02859.1; Type=Frameshift; Positions=254; Evidence={ECO:0000305}; Sequence=AAH02859.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence starting in position 426.; Evidence={ECO:0000305}; Sequence=AAM73658.1; Type=Miscellaneous discrepancy; Note=The cDNA sequence has been translated in the reverse direction.; Evidence={ECO:0000305}; Sequence=BAA91155.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZSCAN32 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSCAN32 Gene

Proteomics data for ZSCAN32 Gene at MOPED

Post-translational modifications for ZSCAN32 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZSCAN32 Gene

Domains for ZSCAN32 Gene

Gene Families for ZSCAN32 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Graphical View of Domain Structure for InterPro Entry

Q9NX65

UniProtKB/Swiss-Prot:

ZSC32_HUMAN :
  • Q9NX65
Domain:
  • Contains 1 KRAB domain.
  • Contains 1 SCAN box domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 6 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZSCAN32: view

No data available for Suggested Antigen Peptide Sequences for ZSCAN32 Gene

Function for ZSCAN32 Gene

Molecular function for ZSCAN32 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZSCAN32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity IBA --
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity --
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with ZSCAN32: view

Phenotypes for ZSCAN32 Gene

genes like me logo Genes that share phenotypes with ZSCAN32: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZSCAN32 Gene

Localization for ZSCAN32 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN32 Gene

Gene Ontology (GO) - Cellular Components for ZSCAN32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZSCAN32: view

No data available for Subcellular locations from COMPARTMENTS for ZSCAN32 Gene

Pathways for ZSCAN32 Gene

SuperPathways for ZSCAN32 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZSCAN32: view

Pathways by source for ZSCAN32 Gene

2 Reactome pathways for ZSCAN32 Gene

Gene Ontology (GO) - Biological Process for ZSCAN32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated --
GO:0006355 regulation of transcription, DNA-templated --
GO:0006357 regulation of transcription from RNA polymerase II promoter IBA --
GO:0006366 transcription from RNA polymerase II promoter IBA --
genes like me logo Genes that share ontologies with ZSCAN32: view

Transcripts for ZSCAN32 Gene

Unigene Clusters for ZSCAN32 Gene

Zinc finger and SCAN domain containing 32:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN32 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d
SP1:
SP2: -
SP3: -
SP4:
SP5: - - - -
SP6: - - -
SP7: - - - - - -

Relevant External Links for ZSCAN32 Gene

GeneLoc Exon Structure for
ZSCAN32
ECgene alternative splicing isoforms for
ZSCAN32

Expression for ZSCAN32 Gene

mRNA expression in normal human tissues for ZSCAN32 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZSCAN32 Gene

SOURCE GeneReport for Unigene cluster for ZSCAN32 Gene Hs.592078

genes like me logo Genes that share expressions with ZSCAN32: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZSCAN32 Gene

Orthologs for ZSCAN32 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN32 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF434 35
  • 99.33 (n)
  • 98.71 (a)
ZSCAN32 36
  • 69 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 14 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 22 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm9772 36
  • 44 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia ZSCAN32 36
  • 24 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 17 (a)
OneToMany
-- 36
  • 27 (a)
OneToMany
Species with no ortholog for ZSCAN32:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN32 Gene

ENSEMBL:
Gene Tree for ZSCAN32 (if available)
TreeFam:
Gene Tree for ZSCAN32 (if available)

Paralogs for ZSCAN32 Gene

Paralogs for ZSCAN32 Gene

Selected SIMAP similar genes for ZSCAN32 Gene using alignment to 10 proteins:

genes like me logo Genes that share paralogs with ZSCAN32: view

Variants for ZSCAN32 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN32 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs7872 -- 3,382,216(-) TCATC(A/G)TAGTT utr-variant-3-prime
rs27228 -- 3,381,933(+) AATTC(C/T)CTCTT intron-variant, utr-variant-3-prime, downstream-variant-500B
rs27229 -- 3,382,413(+) TATTA(C/T)GGTGG utr-variant-3-prime
rs27230 - 3,384,699(+) CTCAT(A/G)AAAGA missense, reference
rs27231 -- 3,384,966(+) TCAAT(A/C/T)AGATC intron-variant

Relevant External Links for ZSCAN32 Gene

HapMap Linkage Disequilibrium report
ZSCAN32

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZSCAN32 Gene

Disorders for ZSCAN32 Gene

No disorders were found for ZSCAN32 Gene.

No data available for UniProtKB/Swiss-Prot for ZSCAN32 Gene

Publications for ZSCAN32 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  3. An empirical framework for binary interactome mapping. (PMID: 19060904) Venkatesan K. … Vidal M. (Nat. Methods 2009) 3
  4. An atlas of combinatorial transcriptional regulation in mouse and man. (PMID: 20211142) Ravasi T. … Hayashizaki Y. (Cell 2010) 3
  5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for ZSCAN32 Gene

Sources for ZSCAN32 Gene

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