ZSCAN30 Gene
protein-coding GIFtS: 38
GCID: GC18M032833
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zinc finger and SCAN domain containing 30(Previous names: zinc finger protein 397 opposite strand, ZNF397 opposite...)
(Previous symbol: ZNF397OS)
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Aliases
for ZSCAN30 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger And SCAN Domain Containing 301 2 | | ZNF397 Opposite Strand1 2 | | Zinc Finger Protein 397 Opposite Strand1 2 3 | | Zinc Finger Protein 397OS2 3 | | ZNF397OS1 2 3 | | ZNF-WYM2 3 | | ZNF9171 2 | | Zinc Finger And SCAN Domain-Containing Protein 302 |
Export aliases for ZSCAN30 gene to outside databasesPrevious GC identifer: GC18M029690 |
Summaries
for ZSCAN30 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZSC30_HUMAN, Q86W11Function: May be involved in transcriptional regulation
|
Genomic Views
for ZSCAN30 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000018.9 NC_018929.1 NT_010966.14
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZSCAN30
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZSCAN30
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZSCAN30 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 18q12.2 Ensembl cytogenetic band: 18q12.2 HGNC cytogenetic band: 18q12.2ZSCAN30 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 18 GeneLoc Exon Structure GeneLoc location for GC18M032833: view genomic region
(about GC identifiers)
Start:
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32,831,023 bp from pter |
End:
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32,870,213 bp from pter |
Size:
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39,191 bases |
Orientation:
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minus strand |
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Proteins
for ZSCAN30 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZSC30_HUMAN, Q86W11 (See
protein sequence)Recommended Name: Zinc finger and SCAN domain-containing protein 30 Size: 494 amino acids; 56364 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=AAL26786.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;
Secondary accessions: B4E0N0 Q6ZNB3 Q96PN3Alternative splicing: 2 isoforms: Q86W11-1 Q86W11-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZSCAN30: NX_Q86W11
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86W11
ZSCAN30 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001106205.1 NP_001159484.1
ENSEMBL proteins: ENSP00000329738 ENSP00000392371 ENSP00000465046 ENSP00000468180 ENSP00000467308 ENSP00000372569
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZSCAN30 for ontologies About GeneDecksing
ZSCAN30 Antibody Products:
Assay Products for ZSCAN30: |
Protein
Domains /
Families
for ZSCAN30 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZSCAN30 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q86W11ProtoNet protein and cluster: Q86W11 1 Blocks protein family: IPB003309 Transcriptional regulator SCAN
UniProtKB/Swiss-Prot: ZSC30_HUMAN, Q86W11Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 7 C2H2-type zinc fingersSimilarity: Contains 1 SCAN box domain |
Function
for ZSCAN30 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZSC30_HUMAN, Q86W11Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN30 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN30 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ZSCAN30 (NM_001112734) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZSCAN30 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN30 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN30 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
IEA | -- | | GO:0003700 | sequence-specific DNA binding transcription factor activity |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
ZSCAN30 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZSCAN30 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZSCAN30
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
5/10 Interacting proteins for ZSCAN30 (ENSP000003297384) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0016032 | viral reproduction |
IEA | -- |
ZSCAN30 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZSCAN30 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZSCAN30
Search CenterWatch for drugs/clinical trials and news about ZSCAN30 / ZSC30
|
Transcripts
for ZSCAN30 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZSCAN30 gene (2 alternative transcripts): NM_001112734.2 NM_001166012.1 Unigene Cluster for ZSCAN30: Zinc finger and SCAN domain containing 30 Hs.619840 [show with all ESTs]Unigene Representative Sequence: AK12869711 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000333206(uc002kym.3) ENST00000420878(uc002kyl.3) ENST00000590777
ENST00000589178 ENST00000588448 ENST00000592278 ENST00000592598 ENST00000592211
ENST00000586922(lincRNA) ENST00000588832 ENST00000383091(uc002kyn.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN30 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN30 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ZSCAN30 (NM_001112734) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZSCAN30 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN30 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZSCAN30
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZSCAN30 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZSCAN30 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZSCAN30 |
Additional cDNA sequence: AF303374.1 AK001503.1 AK057386.1 AK057518.1 AK128697.1 AK131291.1 AK303447.1 AL832180.1 AY234408.1 8 DOTS entries: DT.95090370 DT.95110056 DT.40299345 DT.75191728 DT.95352035 DT.121090861 DT.91776167 DT.97820354
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN30 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b |
|---|
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| SP1: | | | | | | | - | | - | | | | | | |
| SP2: | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | |
ECgene alternative splicing isoforms for ZSCAN30
|
Expression
for ZSCAN30 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZSCAN30 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTACTGGTAC
About this image
See ZSCAN30 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZSCAN30
SOURCE GeneReport for Unigene cluster: Hs.619840
SABiosciences Custom PCR Arrays for ZSCAN30
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZSCAN30
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZSCAN30 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZSCAN30 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZSCAN30 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN30 |
Orthologs
for ZSCAN30 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZSCAN30 (if available)
TreeFam Gene Tree for ZSCAN30 (if available) |
Paralogs
for ZSCAN30 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZSCAN30 gene
- ZNF4962 ZNF4492 ZNF4462 ZSCAN92 ZKSCAN12 ZNF3972 ZNF5002 ZNF2132
- ZNF2322 ZNF2632 ZNF2022 ZKSCAN42 ZNF1742 ZSCAN252 ZNF3962 ZSCAN122
- ZNF3942 ZSCAN212 ZSCAN232 ZNF1652 ZSCAN162 ZKSCAN82 ZSCAN312 ZSCAN222
- ZKSCAN32 ZNF242 ZNF182
18/467 SIMAP similar genes for ZSCAN30 using alignment to 7 protein entries: ZSC30_HUMAN (see all proteins)
(see all similar genes):LOC100128510 SCAND1 ZNF78L1 ZKSCAN8 FANCA ZNF22
ZNF879 DKFZp666C237 ZNF674 ZNF876P DKFZp434K202 HZF36
ZNF146 ZNF480 ZNF501 ZNF572 ZNF577 ZNF595
ZSCAN30 for paralogs About GeneDecksing
|
Genomic Variants
for ZSCAN30 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 18 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZSCAN30 (32831023 - 32870213 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZSCAN30: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZSCAN30 |
|
Disorders
/ Diseases
for ZSCAN30 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZSCAN30 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZSCAN30 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZSCAN30) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of two novel human SCAN domain- containing zinc finger genes ZNF396 and ZNF397. (PubMed id 12801647)1, 2, 3 Wu Y.... Zhao S. (2003)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
|
External Searches for ZSCAN30 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZSCAN30 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZSCAN30 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZSCAN30 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZSCAN30 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZSCAN30 gene:
Search GeneIP for patents involving ZSCAN30
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZSCAN30 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZSCAN30 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZSCAN30 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZSCAN30 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZSCAN30 | | OriGene 3'-UTR Clone for ZSCAN30 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN30 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN30 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZSCAN30 | | OriGene Custom Protein Services for ZSCAN30 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZSCAN30 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZSCAN30 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZSCAN30 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZSCAN30 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZSCAN30 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZSCAN30 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZSCAN30 |
| |  |  |  |  | | | | |
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 | | | ZSCAN30 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN30 |
|  |  |  | | | | ThermoFisher Antibodies for ZSCAN30 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN30 |
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