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Aliases for ZSCAN29 Gene

Aliases for ZSCAN29 Gene

  • Zinc Finger And SCAN Domain Containing 29 2 3 5
  • Zinc Finger Protein 690 2 3 4
  • ZNF690 3 4
  • KOX31-Like Zinc Finger Protein 3
  • EC 2.7.10.1 63
  • EC 2.1.1.43 63
  • Zfp690 3

External Ids for ZSCAN29 Gene

Previous HGNC Symbols for ZSCAN29 Gene

  • ZNF690

Previous GeneCards Identifiers for ZSCAN29 Gene

  • GC15M041443
  • GC15M043650
  • GC15M020498

Summaries for ZSCAN29 Gene

GeneCards Summary for ZSCAN29 Gene

ZSCAN29 (Zinc Finger And SCAN Domain Containing 29) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZKSCAN2.

UniProtKB/Swiss-Prot for ZSCAN29 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN29 Gene

Genomics for ZSCAN29 Gene

Regulatory Elements for ZSCAN29 Gene

Promoters for ZSCAN29 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZSCAN29 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZSCAN29 Gene

Chromosome:
15
Start:
43,358,172 bp from pter
End:
43,371,025 bp from pter
Size:
12,854 bases
Orientation:
Minus strand

Genomic View for ZSCAN29 Gene

Genes around ZSCAN29 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN29 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN29 Gene

Proteins for ZSCAN29 Gene

  • Protein details for ZSCAN29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IWY8-ZSC29_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 29
    Protein Accession:
    Q8IWY8
    Secondary Accessions:
    • B3KVB9
    • Q32M75
    • Q32M76
    • Q8NA40

    Protein attributes for ZSCAN29 Gene

    Size:
    852 amino acids
    Molecular mass:
    96719 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZSCAN29 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSCAN29 Gene

Proteomics data for ZSCAN29 Gene at MOPED

Selected DME Specific Peptides for ZSCAN29 Gene

Post-translational modifications for ZSCAN29 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZSCAN29 Gene

Antibody Products

Domains & Families for ZSCAN29 Gene

Gene Families for ZSCAN29 Gene

Suggested Antigen Peptide Sequences for ZSCAN29 Gene

Graphical View of Domain Structure for InterPro Entry

Q8IWY8

UniProtKB/Swiss-Prot:

ZSC29_HUMAN :
  • Contains 1 SCAN box domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 6 C2H2-type zinc fingers.
Domain:
  • Contains 1 SCAN box domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 6 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZSCAN29: view

Function for ZSCAN29 Gene

Molecular function for ZSCAN29 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Enzyme Numbers (IUBMB) for ZSCAN29 Gene

Gene Ontology (GO) - Molecular Function for ZSCAN29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with ZSCAN29: view

Phenotypes for ZSCAN29 Gene

genes like me logo Genes that share phenotypes with ZSCAN29: view

Animal Model Products

CRISPR Products

miRNA for ZSCAN29 Gene

miRTarBase miRNAs that target ZSCAN29

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZSCAN29 Gene

Localization for ZSCAN29 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN29 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZSCAN29 Gene COMPARTMENTS Subcellular localization image for ZSCAN29 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZSCAN29 Gene

Pathways & Interactions for ZSCAN29 Gene

SuperPathways for ZSCAN29 Gene

No Data Available

Interacting Proteins for ZSCAN29 Gene

Gene Ontology (GO) - Biological Process for ZSCAN29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZSCAN29: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN29 Gene

Drugs & Compounds for ZSCAN29 Gene

No Compound Related Data Available

Transcripts for ZSCAN29 Gene

Unigene Clusters for ZSCAN29 Gene

Zinc finger and SCAN domain containing 29:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN29 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d ^ 5a · 5b
SP1: - -
SP2: - - -
SP3:
SP4: -
SP5: - - - - - - -

Relevant External Links for ZSCAN29 Gene

GeneLoc Exon Structure for
ZSCAN29
ECgene alternative splicing isoforms for
ZSCAN29

Expression for ZSCAN29 Gene

mRNA expression in normal human tissues for ZSCAN29 Gene

Protein differential expression in normal tissues from HIPED for ZSCAN29 Gene

This gene is overexpressed in Brain (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZSCAN29 Gene



SOURCE GeneReport for Unigene cluster for ZSCAN29 Gene Hs.418287

genes like me logo Genes that share expression patterns with ZSCAN29: view

Protein tissue co-expression partners for ZSCAN29 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZSCAN29 Gene

Orthologs for ZSCAN29 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZSCAN29 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZSCAN29 35
  • 88.9 (n)
  • 87.49 (a)
ZSCAN29 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZSCAN29 35
  • 90.12 (n)
  • 88.59 (a)
ZSCAN29 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zscan29 35
  • 86.02 (n)
  • 82.33 (a)
Zscan29 16
Zscan29 36
  • 80 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZSCAN29 35
  • 99.53 (n)
  • 99.06 (a)
ZSCAN29 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zscan29 35
  • 84.74 (n)
  • 79.98 (a)
oppossum
(Monodelphis domestica)
Mammalia ZSCAN29 36
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZSCAN29 36
  • 54 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 49 (a)
ManyToMany
Species with no ortholog for ZSCAN29:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN29 Gene

ENSEMBL:
Gene Tree for ZSCAN29 (if available)
TreeFam:
Gene Tree for ZSCAN29 (if available)

Paralogs for ZSCAN29 Gene

Paralogs for ZSCAN29 Gene

(466) SIMAP similar genes for ZSCAN29 Gene using alignment to 7 proteins:

Pseudogenes.org Pseudogenes for ZSCAN29 Gene

genes like me logo Genes that share paralogs with ZSCAN29: view

Variants for ZSCAN29 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN29 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
VAR_057459 -
VAR_059949 -
rs10865 -- 43,358,432(+) GACTG(C/G/T)TGTTT utr-variant-3-prime
rs1133395 -- 43,358,186(-) AAAAT(C/T)ATGTC utr-variant-3-prime
rs935901 -- 43,359,058(+) ACCCA(C/G)CACTC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN29 Gene

Variant ID Type Subtype PubMed ID
nsv1512 CNV Loss 18451855
nsv1513 CNV Insertion 18451855
esv2618501 CNV Deletion 19546169
esv2020159 CNV Deletion 18987734
esv2749625 CNV Deletion 23290073
esv2430486 CNV Deletion 19546169
esv1003756 CNV Deletion 20482838
esv8406 CNV Loss 19470904

Variation tolerance for ZSCAN29 Gene

Residual Variation Intolerance Score: 89.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.96; 84.02% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZSCAN29 Gene

HapMap Linkage Disequilibrium report
ZSCAN29
Human Gene Mutation Database (HGMD)
ZSCAN29

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSCAN29 Gene

Disorders for ZSCAN29 Gene

Relevant External Links for ZSCAN29

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZSCAN29

No disorders were found for ZSCAN29 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN29 Gene

Publications for ZSCAN29 Gene

  1. Congenital dyserythropoietic anemia type I is caused by mutations in codanin-1. (PMID: 12434312) Dgany O. … Tamary H. (Am. J. Hum. Genet. 2002) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for ZSCAN29 Gene

Sources for ZSCAN29 Gene

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