ZSCAN29 Gene
protein-coding GIFtS: 44
GCID: GC15M043650
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|
zinc finger and SCAN domain containing 29(Previous name: zinc finger protein 690 )
(Previous symbol: ZNF690)
| |
Aliases
for ZSCAN29 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger And SCAN Domain Containing 291 2 | | KOX31-Like Zinc Finger Protein2 | | Zinc Finger Protein 6901 2 3 | | Zinc Finger And SCAN Domain-Containing Protein 292 | | ZNF6901 2 3 | | EC 2.1.1.438 | | Zfp6901 2 | | EC 2.7.10.18 | | FLJ358671 | | |
Export aliases for ZSCAN29 gene to outside databasesPrevious GC identifers: GC15M041443 GC15M020498 |
Summaries
for ZSCAN29 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZSC29_HUMAN, Q8IWY8Function: May be involved in transcriptional regulation
|
Genomic Views
for ZSCAN29 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZSCAN29 gene promoter:
GR GR-beta C/EBPalpha CHOP-10 PPAR-gamma1 POU2F1 POU2F1a PPAR-gamma2 GR-alpha RSRFC4
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZSCAN29
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZSCAN29 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q15.3 Ensembl cytogenetic band: 15q15.3 HGNC cytogenetic band: 15q15.3ZSCAN29 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M043650: view genomic region
(about GC identifiers)
Start:
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43,650,370 bp from pter |
End:
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43,663,223 bp from pter |
Size:
|
12,854 bases |
Orientation:
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minus strand |
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Proteins
for ZSCAN29 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZSC29_HUMAN, Q8IWY8 (See
protein sequence)Recommended Name: Zinc finger and SCAN domain-containing protein 29 Size: 852 amino acids; 96719 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: B3KVB9 Q32M75 Q32M76 Q8NA40Alternative splicing: 4 isoforms: Q8IWY8-1 Q8IWY8-2 Q8IWY8-3 Q8IWY8-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZSCAN29: NX_Q8IWY8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IWY8
2 DME Specific Peptides for ZSCAN29 (Q8IWY8)
ZSCAN29 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_689668.3
ENSEMBL proteins: ENSP00000380174 ENSP00000457835 ENSP00000456089 ENSP00000456883 ENSP00000454548 ENSP00000458119 ENSP00000380170
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZSCAN29 for ontologies About GeneDecksing
ZSCAN29 Antibody Products:
Assay Products for ZSCAN29: |
Protein
Domains /
Families
for ZSCAN29 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZSCAN29 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IWY8ProtoNet protein and cluster: Q8IWY8 2 Blocks protein families: IPB003309 Transcriptional regulator SCAN IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZSC29_HUMAN, Q8IWY8Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 6 C2H2-type zinc fingersSimilarity: Contains 1 SCAN box domain |
Function
for ZSCAN29 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZSC29_HUMAN, Q8IWY8Function: May be involved in transcriptional regulationEnzyme Numbers (IUBMB): EC 2.1.1.432 EC 2.7.10.12
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN29 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN29
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZSCAN29 (NM_152455) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZSCAN29 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN29 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN29 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
IEA | -- | | GO:0003700 | sequence-specific DNA binding transcription factor activity |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
ZSCAN29 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZSCAN29 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZSCAN29
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0016032 | viral reproduction |
IEA | -- |
ZSCAN29 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZSCAN29 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZSCAN29
Search CenterWatch for drugs/clinical trials and news about ZSCAN29 / ZSC29
|
Transcripts
for ZSCAN29 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZSCAN29 gene: NM_152455.3 Unigene Cluster for ZSCAN29: Zinc finger and SCAN domain containing 29 Hs.418287 [show with all ESTs]Unigene Representative Sequence: NM_1524558 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000396976(uc001zrj.1 uc001zrk.1 uc010bdf.1 uc001zrl.1)
ENST00000566849(uc001zrm.3) ENST00000562072 ENST00000568898 ENST00000570181
ENST00000561661 ENST00000563508 ENST00000396972(uc010bdg.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN29 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZSCAN29
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZSCAN29 (NM_152455) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZSCAN29 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN29 |
Additional cDNA sequence: AF525399.1 AK023525.1 AK093186.1 AK093377.1 AK098289.1 AK122788.1 AK123753.1 BC017179.2 BC040682.1 BC043612.1 BC062551.1 BC109270.1 BC109271.1 8 DOTS entries: DT.311211 DT.99950834 DT.101983030 DT.310605 DT.121049059 DT.97808781 DT.121049134 DT.91801390 24/102 AceView cDNA sequences (see all 102): AK093186 NM_152455 BU931150 BM929580 BM792047 BQ055801 BU556760 BQ061821 AX747979 BX111371 CR617733 AW020943 AA868761 AI368137 BC040682 BU674110 BC017179 AF525399 BC043612 AI932247 BQ056534 BM727568 BU849689 AI497994
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN29 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b |
|---|
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| SP1: | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | | | - | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | | |
ECgene alternative splicing isoforms for ZSCAN29
|
Expression
for ZSCAN29 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZSCAN29 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCCAGATGGC
About this image
See ZSCAN29 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZSCAN29
SOURCE GeneReport for Unigene cluster: Hs.418287
SABiosciences Custom PCR Arrays for ZSCAN29
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZSCAN29
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZSCAN29 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZSCAN29 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZSCAN29 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN29 |
Orthologs
for ZSCAN29 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for ZSCAN29 gene from 1/6 species (see all 6) About this table
ENSEMBL Gene Tree for ZSCAN29 (if available)
TreeFam Gene Tree for ZSCAN29 (if available) |
Paralogs
for ZSCAN29 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZSCAN29 gene
- ZSCAN322 ZKSCAN22 SCAND12 ZSCAN202
18/464 SIMAP similar genes for ZSCAN29 using alignment to 7 protein entries: ZSC29_HUMAN (see all proteins)
(see all similar genes):SCAND1 ZNF394 ZNF197 ZNF396 ZNF213 ZNF78L1
LOC100128510 kr-znf3 ZKSCAN8 ZNF444 ZNF582 ZSCAN31
ZFS-5 ZKSCAN5 ZNF132 ZNF211 ZNF551 ZNF714
ZSCAN29 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for ZSCAN29
PGOHUM00000238678 PGOHUM00000262455 PGOHUM00000262456
|
Genomic Variants
for ZSCAN29 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZSCAN29 (43650370 - 43663223 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for ZSCAN29
5 Indels: 34313 102091 61441 45340 40090 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZSCAN29 |
|
Disorders
/ Diseases
for ZSCAN29 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZSCAN29 for disorders About GeneDecksing
4  diseases for ZSCAN29: About MalaCardscongenital dyserythropoietic anemia type i congenital dyserythropoietic anemia dyserythropoietic anemia anemia
Export disorders for ZSCAN29 gene to outside databases
|
Publications
for ZSCAN29 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZSCAN29 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZSCAN29) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Congenital dyserythropoietic anemia type I is caused by mutations in codanin-1. (PubMed id 12434312)1, 2, 3 Dgany O.... Tamary H. (2002)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZSCAN29 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZSCAN29 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZSCAN29 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZSCAN29 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZSCAN29 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZSCAN29 gene:
Search GeneIP for patents involving ZSCAN29
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZSCAN29 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZSCAN29 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZSCAN29 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZSCAN29 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZSCAN29 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZSCAN29 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZSCAN29 |
| |
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| |  |  |  |  | | | | |
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 | | | ZSCAN29 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN29 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZSCAN29 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN29 |
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