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Aliases for ZSCAN29 Gene

Aliases for ZSCAN29 Gene

  • Zinc Finger And SCAN Domain Containing 29 2 3 5
  • Zinc Finger Protein 690 2 3 4
  • ZNF690 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 29 3
  • KOX31-Like Zinc Finger Protein 3
  • EC 2.7.10.1 56
  • EC 2.1.1.43 56
  • Zfp690 3

External Ids for ZSCAN29 Gene

Previous HGNC Symbols for ZSCAN29 Gene

  • ZNF690

Previous GeneCards Identifiers for ZSCAN29 Gene

  • GC15M041443
  • GC15M043650
  • GC15M020498

Summaries for ZSCAN29 Gene

GeneCards Summary for ZSCAN29 Gene

ZSCAN29 (Zinc Finger And SCAN Domain Containing 29) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZKSCAN2.

UniProtKB/Swiss-Prot for ZSCAN29 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZSCAN29 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN29 Gene

Genomics for ZSCAN29 Gene

GeneHancer (GH) Regulatory Elements for ZSCAN29 Gene

Promoters and enhancers for ZSCAN29 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I043370 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 -0.1 -65 2.1 HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A DMAP1 ZNF2 POLR2B E2F8 ZSCAN29 TUBGCP4 ADAL TGM7 RN7SL487P
GH15I043491 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 56.5 -122.2 -122208 3.2 PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B YY1 SLC30A9 POLR2B TP53BP1 ZSCAN29 ADAL TGM7 CTDSPL2 MFAP1 UBR1 TUBGCP4 CDAN1 GC15M043494
GH15I043508 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 40.3 -139.1 -139106 3.5 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B E2F8 TP53BP1 MAP1A GC15M043498 ZSCAN29 CTDSPL2 ADAL CDAN1 LRRC57 LCMT2 UBR1
GH15I043513 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 24.5 -145.3 -145324 6.4 HDGF ATF1 GLIS2 ZNF143 ATF7 REST ZNF592 SMARCA4 KDM1A CTCF MAP1A GC15P043517 ZSCAN29 ADAL
GH15I044192 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 23 -823.2 -823249 3.4 PKNOX1 SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B GLIS2 ZNF213 ZNF143 KLF7 FRMD5 ZSCAN29 CTDSPL2 MFAP1 CATSPER2 STRCP1 ADAL GC15P044099
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZSCAN29 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZSCAN29 gene promoter:

Genomic Locations for ZSCAN29 Gene

Genomic Locations for ZSCAN29 Gene
chr15:43,358,172-43,371,025
(GRCh38/hg38)
Size:
12,854 bases
Orientation:
Minus strand
chr15:43,650,370-43,663,223
(GRCh37/hg19)

Genomic View for ZSCAN29 Gene

Genes around ZSCAN29 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN29 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN29 Gene

Proteins for ZSCAN29 Gene

  • Protein details for ZSCAN29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IWY8-ZSC29_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 29
    Protein Accession:
    Q8IWY8
    Secondary Accessions:
    • B3KVB9
    • Q32M75
    • Q32M76
    • Q8NA40

    Protein attributes for ZSCAN29 Gene

    Size:
    852 amino acids
    Molecular mass:
    96719 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZSCAN29 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSCAN29 Gene

Selected DME Specific Peptides for ZSCAN29 Gene

Q8IWY8:
  • ALVSVRV
  • HQRTHTGEKPY

Post-translational modifications for ZSCAN29 Gene

No Post-translational modifications

Domains & Families for ZSCAN29 Gene

Gene Families for ZSCAN29 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted secreted proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for ZSCAN29 Gene

Graphical View of Domain Structure for InterPro Entry

Q8IWY8

UniProtKB/Swiss-Prot:

ZSC29_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZSCAN29: view

Function for ZSCAN29 Gene

Molecular function for ZSCAN29 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Enzyme Numbers (IUBMB) for ZSCAN29 Gene

Phenotypes From GWAS Catalog for ZSCAN29 Gene

Gene Ontology (GO) - Molecular Function for ZSCAN29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN29: view

Phenotypes for ZSCAN29 Gene

genes like me logo Genes that share phenotypes with ZSCAN29: view

Animal Model Products

miRNA for ZSCAN29 Gene

miRTarBase miRNAs that target ZSCAN29

Clone Products

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZSCAN29 Gene

Localization for ZSCAN29 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN29 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZSCAN29 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Actin filaments (2)
  • Nucleoplasm (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZSCAN29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IBA --
genes like me logo Genes that share ontologies with ZSCAN29: view

Pathways & Interactions for ZSCAN29 Gene

SuperPathways for ZSCAN29 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZSCAN29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription by RNA polymerase II IEA --
genes like me logo Genes that share ontologies with ZSCAN29: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN29 Gene

Drugs & Compounds for ZSCAN29 Gene

No Compound Related Data Available

Transcripts for ZSCAN29 Gene

Unigene Clusters for ZSCAN29 Gene

Zinc finger and SCAN domain containing 29:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN29 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d ^ 5a · 5b
SP1: - -
SP2: - - -
SP3:
SP4: -
SP5: - - - - - - -

Relevant External Links for ZSCAN29 Gene

GeneLoc Exon Structure for
ZSCAN29
ECgene alternative splicing isoforms for
ZSCAN29

Expression for ZSCAN29 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZSCAN29 Gene

Protein differential expression in normal tissues from HIPED for ZSCAN29 Gene

This gene is overexpressed in Brain (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZSCAN29 Gene



Protein tissue co-expression partners for ZSCAN29 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZSCAN29 Gene:

ZSCAN29

SOURCE GeneReport for Unigene cluster for ZSCAN29 Gene:

Hs.418287

Evidence on tissue expression from TISSUES for ZSCAN29 Gene

  • Liver(4.4)
  • Blood(4.2)
genes like me logo Genes that share expression patterns with ZSCAN29: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZSCAN29 Gene

Orthologs for ZSCAN29 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZSCAN29 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZSCAN29 33 34
  • 99.53 (n)
dog
(Canis familiaris)
Mammalia ZSCAN29 33 34
  • 90.12 (n)
cow
(Bos Taurus)
Mammalia ZSCAN29 33 34
  • 88.9 (n)
mouse
(Mus musculus)
Mammalia Zscan29 33 16 34
  • 86.02 (n)
rat
(Rattus norvegicus)
Mammalia Zscan29 33
  • 84.74 (n)
oppossum
(Monodelphis domestica)
Mammalia ZSCAN29 34
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZSCAN29 34
  • 54 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 49 (a)
ManyToMany
Species where no ortholog for ZSCAN29 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN29 Gene

ENSEMBL:
Gene Tree for ZSCAN29 (if available)
TreeFam:
Gene Tree for ZSCAN29 (if available)

Paralogs for ZSCAN29 Gene

Paralogs for ZSCAN29 Gene

(466) SIMAP similar genes for ZSCAN29 Gene using alignment to 7 proteins:

Pseudogenes.org Pseudogenes for ZSCAN29 Gene

genes like me logo Genes that share paralogs with ZSCAN29: view

Variants for ZSCAN29 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN29 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000117155 -- 43,360,479(-) T/C 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1000237121 -- 43,360,819(-) C/T 3_prime_UTR_variant, downstream_transcript_variant, genic_downstream_transcript_variant
rs1000882208 -- 43,360,972(-) C/G 3_prime_UTR_variant, downstream_transcript_variant, genic_downstream_transcript_variant
rs1001353317 -- 43,367,882(-) C/T intron_variant
rs1001561541 -- 43,371,101(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN29 Gene

Variant ID Type Subtype PubMed ID
esv1003756 CNV deletion 20482838
esv2020159 CNV deletion 18987734
esv2430486 CNV deletion 19546169
esv2618501 CNV deletion 19546169
esv2749625 CNV deletion 23290073
esv3552373 CNV deletion 23714750
esv8406 CNV loss 19470904
nsv1071208 CNV deletion 25765185
nsv1138362 CNV deletion 24896259
nsv1151412 CNV deletion 26484159
nsv1512 CNV deletion 18451855
nsv1513 CNV insertion 18451855
nsv957953 CNV deletion 24416366

Variation tolerance for ZSCAN29 Gene

Residual Variation Intolerance Score: 89.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.96; 84.02% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZSCAN29 Gene

Human Gene Mutation Database (HGMD)
ZSCAN29
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZSCAN29

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSCAN29 Gene

Disorders for ZSCAN29 Gene

Additional Disease Information for ZSCAN29

No disorders were found for ZSCAN29 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN29 Gene

Publications for ZSCAN29 Gene

  1. Congenital dyserythropoietic anemia type I is caused by mutations in codanin-1. (PMID: 12434312) Dgany O … Tamary H (American journal of human genetics 2002) 2 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  5. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58

Products for ZSCAN29 Gene

Sources for ZSCAN29 Gene

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