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Aliases for ZSCAN26 Gene

Aliases for ZSCAN26 Gene

  • Zinc Finger And SCAN Domain Containing 26 2 3 5
  • Zinc Finger Protein 187 2 3 4
  • ZNF187 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 26 3
  • Protein SRE-ZBP 4
  • SRE-ZBP 3
  • SREZBP 3

External Ids for ZSCAN26 Gene

Previous HGNC Symbols for ZSCAN26 Gene

  • ZNF187

Previous GeneCards Identifiers for ZSCAN26 Gene

  • GC06P028235

Summaries for ZSCAN26 Gene

GeneCards Summary for ZSCAN26 Gene

ZSCAN26 (Zinc Finger And SCAN Domain Containing 26) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF35.

UniProtKB/Swiss-Prot for ZSCAN26 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN26 Gene

Genomics for ZSCAN26 Gene

Regulatory Elements for ZSCAN26 Gene

Enhancers for ZSCAN26 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F027862 1 Ensembl ENCODE 58.7 -398.3 -398343 12.7 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YBX1 YY1 SLC30A9 ZNF143 ZNF263 ZKSCAN8 ZKSCAN3 ZSCAN9 GUSBP2 ZSCAN26 ZKSCAN4 ZSCAN23 ZNF391 ZNF603P PGBD1
GH06F027591 1.3 Ensembl ENCODE 39 -674.0 -674012 2.8 PKNOX1 ARNT MLX WRNIP1 ARID4B SIN3A FEZF1 ZNF2 SLC30A9 ZNF302 ABT1 ZSCAN26 ZKSCAN3 ZNF391 ZKSCAN8 ZKSCAN4 ZSCAN23 ZNF322 PGBD1 ZSCAN9
GH06F028894 0.5 ENCODE 22.2 +629.9 629880 3.9 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF416 ZNF263 ZKSCAN3 ZKSCAN8 ZKSCAN4 TRIM27 ZSCAN9 ZSCAN26 ZNF311 ZNF603P HCG4P7 ZFP57
GH06F027684 0.9 Ensembl ENCODE 19 -582.4 -582414 1.2 ARNT CREB3L1 SIN3A ARID4B FEZF1 DMAP1 ZNF2 SLC30A9 SP3 KAT8 ZKSCAN3 ZKSCAN4 ZKSCAN8 ZSCAN9 ZSCAN26 ZNF204P ZNF391 PGBD1 ZSCAN23 GUSBP2
GH06F028977 0.9 Ensembl ENCODE 19 +713.5 713465 6.7 CREB3L1 MLX FEZF1 DMAP1 YBX1 YY1 ZNF143 SP3 NFYC MEF2D ZKSCAN3 ZKSCAN8 ZKSCAN4 TRIM27 HLA-K ZNF311 MICD ZSCAN9 HLA-W HCG4B
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZSCAN26 on UCSC Golden Path with GeneCards custom track

Promoters for ZSCAN26 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001494383 391 2400 HDGF ARNT CREB3L1 MLX WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ZNF2

Genomic Location for ZSCAN26 Gene

Chromosome:
6
Start:
28,267,010 bp from pter
End:
28,278,224 bp from pter
Size:
11,215 bases
Orientation:
Plus strand

Genomic View for ZSCAN26 Gene

Genes around ZSCAN26 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN26 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN26 Gene

Proteins for ZSCAN26 Gene

  • Protein details for ZSCAN26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q16670-ZSC26_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 26
    Protein Accession:
    Q16670
    Secondary Accessions:
    • Q5JPG4
    • Q7Z3Q6
    • Q96A17

    Protein attributes for ZSCAN26 Gene

    Size:
    478 amino acids
    Molecular mass:
    55254 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAD97775.1; Type=Frameshift; Positions=155, 353; Evidence={ECO:0000305};

    Alternative splice isoforms for ZSCAN26 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSCAN26 Gene

Post-translational modifications for ZSCAN26 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZSCAN26 Gene

Domains & Families for ZSCAN26 Gene

Gene Families for ZSCAN26 Gene

Suggested Antigen Peptide Sequences for ZSCAN26 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q16670

UniProtKB/Swiss-Prot:

ZSC26_HUMAN :
  • Contains 1 SCAN box domain.
  • Contains 8 C2H2-type zinc fingers.
Domain:
  • Contains 1 SCAN box domain.
Similarity:
  • Contains 8 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZSCAN26: view

Function for ZSCAN26 Gene

Molecular function for ZSCAN26 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
UniProtKB/Swiss-Prot Induction:
By serum stimulation.

Gene Ontology (GO) - Molecular Function for ZSCAN26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003700 transcription factor activity, sequence-specific DNA binding IEA,NAS 1569959
GO:0005515 protein binding IPI 25416956
GO:0043565 sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN26: view
genes like me logo Genes that share phenotypes with ZSCAN26: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZSCAN26 Gene

Localization for ZSCAN26 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN26 Gene

Gene Ontology (GO) - Cellular Components for ZSCAN26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,NAS 1569959
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with ZSCAN26: view

No data available for Subcellular locations from COMPARTMENTS for ZSCAN26 Gene

Pathways & Interactions for ZSCAN26 Gene

SuperPathways for ZSCAN26 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZSCAN26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,NAS 1569959
genes like me logo Genes that share ontologies with ZSCAN26: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN26 Gene

Transcripts for ZSCAN26 Gene

Unigene Clusters for ZSCAN26 Gene

Zinc finger and SCAN domain containing 26:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN26 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c · 6d · 6e ^ 7a · 7b · 7c · 7d · 7e ^ 8a · 8b · 8c · 8d · 8e · 8f ·
SP1: - - - -
SP2: - - - - - - - -
SP3: - - -
SP4: - - -
SP5: - - - - - - -
SP6: - -
SP7: -
SP8: - - -
SP9: -
SP10: -
SP11: - - - - - - - - - - - - - - -
SP12: - - -
SP13:

ExUns: 8g
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:

Relevant External Links for ZSCAN26 Gene

GeneLoc Exon Structure for
ZSCAN26
ECgene alternative splicing isoforms for
ZSCAN26

Expression for ZSCAN26 Gene

mRNA expression in normal human tissues for ZSCAN26 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZSCAN26 Gene

This gene is overexpressed in CD8 Tcells (47.6), Blymphocyte (11.7), and Ovary (9.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZSCAN26 Gene



Protein tissue co-expression partners for ZSCAN26 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZSCAN26 Gene:

ZSCAN26

SOURCE GeneReport for Unigene cluster for ZSCAN26 Gene:

Hs.157883
genes like me logo Genes that share expression patterns with ZSCAN26: view

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZSCAN26 Gene

Orthologs for ZSCAN26 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN26 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF187 34
  • 99.58 (n)
cow
(Bos Taurus)
Mammalia ZSCAN26 34
  • 85.73 (n)
dog
(Canis familiaris)
Mammalia ZSCAN26 34
  • 83.44 (n)
rat
(Rattus norvegicus)
Mammalia Zfp187 34
  • 79.9 (n)
mouse
(Mus musculus)
Mammalia Zscan26 34 16
  • 78.57 (n)
Species where no ortholog for ZSCAN26 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN26 Gene

ENSEMBL:
Gene Tree for ZSCAN26 (if available)
TreeFam:
Gene Tree for ZSCAN26 (if available)

Paralogs for ZSCAN26 Gene

Paralogs for ZSCAN26 Gene

(446) SIMAP similar genes for ZSCAN26 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZSCAN26: view

Variants for ZSCAN26 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN26 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs112093847 -- 28,266,986(+) AAAAA(-/AACAAAAAAAAAAC/AACAAAAAAAAAC/ACAAAAAAAAAC/CAAAAAAAAAC)CCCCA upstream-variant-2KB
rs112468414 -- 28,277,222(+) TCCCT(A/G)CCTCT utr-variant-3-prime
rs113269107 -- 28,272,152(+) TCAAC(A/G/T)GTGCT intron-variant, reference, missense, utr-variant-5-prime
rs113364767 -- 28,273,789(+) CATAG(C/G)TCACT intron-variant
rs113661051 -- 28,278,596(+) TTTGC(-/T)TTTTT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN26 Gene

Variant ID Type Subtype PubMed ID
nsv830620 CNV loss 17160897
nsv950146 CNV duplication 24416366

Relevant External Links for ZSCAN26 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZSCAN26

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ZSCAN26 Gene

Disorders for ZSCAN26 Gene

Relevant External Links for ZSCAN26

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZSCAN26

No disorders were found for ZSCAN26 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN26 Gene

Publications for ZSCAN26 Gene

  1. Expression cloning of a novel zinc finger protein that binds to the c-fos serum response element. (PMID: 1569959) Attar R.M. … Gilman M.Z. (Mol. Cell. Biol. 1992) 2 3 4 64
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  5. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3 64

Products for ZSCAN26 Gene

Sources for ZSCAN26 Gene

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