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Aliases for ZSCAN26 Gene

Aliases for ZSCAN26 Gene

  • Zinc Finger And SCAN Domain Containing 26 2 3 5
  • Zinc Finger Protein 187 2 3 4
  • ZNF187 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 26 3
  • Protein SRE-ZBP 4
  • SRE-ZBP 3
  • SREZBP 3

External Ids for ZSCAN26 Gene

Previous HGNC Symbols for ZSCAN26 Gene

  • ZNF187

Previous GeneCards Identifiers for ZSCAN26 Gene

  • GC06P028235

Summaries for ZSCAN26 Gene

GeneCards Summary for ZSCAN26 Gene

ZSCAN26 (Zinc Finger And SCAN Domain Containing 26) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF397.

UniProtKB/Swiss-Prot for ZSCAN26 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZSCAN26 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN26 Gene

Genomics for ZSCAN26 Gene

Regulatory Elements for ZSCAN26 Gene

Enhancers for ZSCAN26 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06H027591 1.4 Ensembl ENCODE 29.9 -674.1 -674111 2 HDGF PKNOX1 MLX ARNT ARID4B SIN3A FEZF1 ZNF2 SLC30A9 ZNF766 ZSCAN12 ZSCAN23 ZKSCAN8 ZNF322 ZKSCAN3 ZSCAN26 PGBD1 ABT1 ZNF391 ZNF192P1
GH06H027805 2 FANTOM5 Ensembl ENCODE dbSUPER 19.3 -454.9 -454896 12 HNRNPUL1 HDGF PKNOX1 FOXA2 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZKSCAN8 ZNF603P ZSCAN12 ZKSCAN3 ZSCAN9 ZKSCAN4 ZSCAN26 ZNF192P1 HIST1H4K ZNF204P
GH06H027547 1.3 Ensembl ENCODE 28.2 -718.8 -718771 2 HDGF ARNT ARID4B FEZF1 ZNF2 FOS SP3 REST ZNF592 MIER3 ZSCAN12 ZKSCAN8 ZSCAN9 ZNF322 ZKSCAN3 ZSCAN23 ABT1 ZNF391 ZSCAN26 ZKSCAN4
GH06H027887 1.8 FANTOM5 ENCODE dbSUPER 19.3 -373.5 -373530 11 ZFP64 DMAP1 YY1 ZNF143 NFYC SSRP1 ZNF610 RCOR2 NBN NR2C1 ZKSCAN4 ZKSCAN8 ZKSCAN3 ZSCAN9 ZNF603P ZSCAN12 ZSCAN26 HIST1H4K HIST1H3H HIST1H2BN
GH06H028596 1.3 Ensembl ENCODE 22 +330.8 330794 1 ARNT FEZF1 DMAP1 BRCA1 ZNF2 GTF3C2 ZNF143 FOS KLF7 DEK ZKSCAN8 ZSCAN12 ZNF603P ZSCAN23 ZSCAN9 ZKSCAN3 ZSCAN26 ZKSCAN4 GPX5 OR2E1P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZSCAN26 on UCSC Golden Path with GeneCards custom track

Promoters for ZSCAN26 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000195211 290 1401 HDGF MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1

Genomic Location for ZSCAN26 Gene

Chromosome:
6
Start:
28,267,010 bp from pter
End:
28,278,224 bp from pter
Size:
11,215 bases
Orientation:
Plus strand

Genomic View for ZSCAN26 Gene

Genes around ZSCAN26 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN26 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN26 Gene

Proteins for ZSCAN26 Gene

  • Protein details for ZSCAN26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q16670-ZSC26_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 26
    Protein Accession:
    Q16670
    Secondary Accessions:
    • Q5JPG4
    • Q7Z3Q6
    • Q96A17

    Protein attributes for ZSCAN26 Gene

    Size:
    478 amino acids
    Molecular mass:
    55254 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAD97775.1; Type=Frameshift; Positions=155, 353; Evidence={ECO:0000305};

    Alternative splice isoforms for ZSCAN26 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSCAN26 Gene

Post-translational modifications for ZSCAN26 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZSCAN26 Gene

Domains & Families for ZSCAN26 Gene

Gene Families for ZSCAN26 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for ZSCAN26 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZSCAN26: view

No data available for UniProtKB/Swiss-Prot for ZSCAN26 Gene

Function for ZSCAN26 Gene

Molecular function for ZSCAN26 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
UniProtKB/Swiss-Prot Induction:
By serum stimulation.

Phenotypes From GWAS Catalog for ZSCAN26 Gene

Gene Ontology (GO) - Molecular Function for ZSCAN26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding NAS,IEA 1569959
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN26: view
genes like me logo Genes that share phenotypes with ZSCAN26: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZSCAN26 Gene

Localization for ZSCAN26 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN26 Gene

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleus (4)
  • Nucleoli (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZSCAN26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus NAS,IEA 1569959
GO:0005654 nucleoplasm IDA --
GO:0005829 cytosol IDA --
genes like me logo Genes that share ontologies with ZSCAN26: view

No data available for Subcellular locations from COMPARTMENTS for ZSCAN26 Gene

Pathways & Interactions for ZSCAN26 Gene

SuperPathways for ZSCAN26 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZSCAN26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,NAS 1569959
genes like me logo Genes that share ontologies with ZSCAN26: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN26 Gene

Drugs & Compounds for ZSCAN26 Gene

No Compound Related Data Available

Transcripts for ZSCAN26 Gene

Unigene Clusters for ZSCAN26 Gene

Zinc finger and SCAN domain containing 26:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN26 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c · 6d · 6e ^ 7a · 7b · 7c · 7d · 7e ^ 8a · 8b · 8c · 8d · 8e · 8f ·
SP1: - - - -
SP2: - - - - - - - -
SP3: - - -
SP4: - - -
SP5: - - - - - - -
SP6: - -
SP7: -
SP8: - - -
SP9: -
SP10: -
SP11: - - - - - - - - - - - - - - -
SP12: - - -
SP13:

ExUns: 8g
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:

Relevant External Links for ZSCAN26 Gene

GeneLoc Exon Structure for
ZSCAN26
ECgene alternative splicing isoforms for
ZSCAN26

Expression for ZSCAN26 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZSCAN26 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZSCAN26 Gene

This gene is overexpressed in CD8 Tcells (47.6), Blymphocyte (11.7), and Ovary (9.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZSCAN26 Gene



Protein tissue co-expression partners for ZSCAN26 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZSCAN26 Gene:

ZSCAN26

SOURCE GeneReport for Unigene cluster for ZSCAN26 Gene:

Hs.157883
genes like me logo Genes that share expression patterns with ZSCAN26: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZSCAN26 Gene

Orthologs for ZSCAN26 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN26 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF187 33
  • 99.58 (n)
cow
(Bos Taurus)
Mammalia ZSCAN26 33
  • 85.73 (n)
dog
(Canis familiaris)
Mammalia ZSCAN26 33
  • 83.44 (n)
rat
(Rattus norvegicus)
Mammalia Zfp187 33
  • 79.9 (n)
mouse
(Mus musculus)
Mammalia Zscan26 33 16
  • 78.57 (n)
Species where no ortholog for ZSCAN26 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN26 Gene

ENSEMBL:
Gene Tree for ZSCAN26 (if available)
TreeFam:
Gene Tree for ZSCAN26 (if available)

Paralogs for ZSCAN26 Gene

(446) SIMAP similar genes for ZSCAN26 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZSCAN26: view

Variants for ZSCAN26 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN26 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000041417 -- 28,271,488(+) CGAGT(A/C)GCTTG intron-variant
rs1000139158 -- 28,278,264(+) GCAGT(A/G)TTCTA downstream-variant-500B
rs1000293759 -- 28,270,239(+) AATAA(C/T)TATCA intron-variant
rs1000407622 -- 28,277,956(+) ATGCA(A/G)TTTTG utr-variant-3-prime
rs1001041105 -- 28,273,241(+) AACAT(C/G)TCTTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN26 Gene

Variant ID Type Subtype PubMed ID
nsv830620 CNV loss 17160897
nsv950146 CNV duplication 24416366

Relevant External Links for ZSCAN26 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZSCAN26

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ZSCAN26 Gene

Disorders for ZSCAN26 Gene

Relevant External Links for ZSCAN26

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZSCAN26

No disorders were found for ZSCAN26 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN26 Gene

Publications for ZSCAN26 Gene

  1. Expression cloning of a novel zinc finger protein that binds to the c-fos serum response element. (PMID: 1569959) Attar RM … Gilman MZ (Molecular and cellular biology 1992) 2 3 4 60
  2. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 60
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 60
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 60

Products for ZSCAN26 Gene

Sources for ZSCAN26 Gene

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