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Aliases for ZSCAN23 Gene

Aliases for ZSCAN23 Gene

  • Zinc Finger And SCAN Domain Containing 23 2 3 5
  • Zinc Finger Protein 453 2 3 4
  • Zinc Finger Protein 390 2 3 4
  • ZNF390 3 4
  • ZNF453 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 23 3
  • DJ29K1.3.1 3
  • DJ29K1.3 3

External Ids for ZSCAN23 Gene

Previous HGNC Symbols for ZSCAN23 Gene

  • ZNF453
  • ZNF390

Previous GeneCards Identifiers for ZSCAN23 Gene

  • GC06M028513
  • GC06U901203
  • GC06M028399
  • GC06M028206

Summaries for ZSCAN23 Gene

GeneCards Summary for ZSCAN23 Gene

ZSCAN23 (Zinc Finger And SCAN Domain Containing 23) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZSCAN12.

UniProtKB/Swiss-Prot for ZSCAN23 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN23 Gene

Genomics for ZSCAN23 Gene

Regulatory Elements for ZSCAN23 Gene

Enhancers for ZSCAN23 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G027862 1.7 Ensembl ENCODE dbSUPER 43.7 +575.3 575307 12.7 CREB3L1 MLX AGO1 ZFP64 DMAP1 YBX1 FEZF1 YY1 SLC30A9 ZNF143 ZKSCAN3 ZKSCAN8 ZSCAN9 ZSCAN26 ZSCAN23 ZNF603P ZKSCAN4 ZNF391 PGBD1 ZNF192P1
GH06G027494 1.4 Ensembl ENCODE 29.3 +948.3 948326 1.7 CREB3L1 FEZF1 ZNF143 ZNF263 SP3 TBX21 ZFP41 MEF2D SSRP1 ZNF610 ZKSCAN8 ZKSCAN3 ZSCAN9 ZNF322 ZNF391 ABT1 ZNF204P ZSCAN23 ZKSCAN4 HMGN4
GH06G028789 1.7 Ensembl ENCODE dbSUPER 20 -346.2 -346210 1.8 CREB3L1 ZFP64 DMAP1 SP3 NFYC MEF2D SSRP1 ZNF610 GLIS1 RCOR2 ZKSCAN8 ZKSCAN3 ZSCAN9 ZSCAN23 TRIM27 ZNF311 ZSCAN26 ZFP57 ZKSCAN4 ZNF603P
GH06G028596 1.4 Ensembl ENCODE 21.8 -153.8 -153830 1.8 PKNOX1 MLX ARNT FEZF1 DMAP1 ZNF2 ZNF766 CBX5 ZNF143 FOS ZNF603P ZKSCAN8 ZSCAN26 ZSCAN23 ZSCAN9 ZKSCAN3 ZKSCAN4 GPX5 OR2E1P COX11P1
GH06G028353 1.6 Ensembl ENCODE dbSUPER 17.1 +88.5 88515 4.7 HDGF PKNOX1 FOXA2 CREB3L1 ARNT ZFP64 SIN3A ARID4B DMAP1 ZNF2 ZNF603P ZSCAN23 ZKSCAN3 ZSCAN31 ZKSCAN8 OR2B7P ZNF391
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZSCAN23 on UCSC Golden Path with GeneCards custom track

Promoters for ZSCAN23 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000195228 673 1399 PKNOX1 ATF1 WRNIP1 ZNF2 ETS1 ZNF121 ZNF143 FOS ZHX2 REST

Genomic Location for ZSCAN23 Gene

Chromosome:
6
Start:
28,425,531 bp from pter
End:
28,443,974 bp from pter
Size:
18,444 bases
Orientation:
Minus strand

Genomic View for ZSCAN23 Gene

Genes around ZSCAN23 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN23 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN23 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN23 Gene

Proteins for ZSCAN23 Gene

  • Protein details for ZSCAN23 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q3MJ62-ZSC23_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 23
    Protein Accession:
    Q3MJ62
    Secondary Accessions:
    • Q96KV9

    Protein attributes for ZSCAN23 Gene

    Size:
    389 amino acids
    Molecular mass:
    44955 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAC44641.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for ZSCAN23 Gene

Post-translational modifications for ZSCAN23 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZSCAN23 Gene

No data available for DME Specific Peptides for ZSCAN23 Gene

Domains & Families for ZSCAN23 Gene

Gene Families for ZSCAN23 Gene

Suggested Antigen Peptide Sequences for ZSCAN23 Gene

Graphical View of Domain Structure for InterPro Entry

Q3MJ62

UniProtKB/Swiss-Prot:

ZSC23_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZSCAN23: view

Function for ZSCAN23 Gene

Molecular function for ZSCAN23 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZSCAN23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN23: view

Phenotypes for ZSCAN23 Gene

GenomeRNAi human phenotypes for ZSCAN23:
genes like me logo Genes that share phenotypes with ZSCAN23: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZSCAN23 Gene

Localization for ZSCAN23 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN23 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZSCAN23 gene
Compartment Confidence
extracellular 5
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZSCAN23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with ZSCAN23: view

Pathways & Interactions for ZSCAN23 Gene

SuperPathways for ZSCAN23 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZSCAN23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZSCAN23: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN23 Gene

Drugs & Compounds for ZSCAN23 Gene

No Compound Related Data Available

Transcripts for ZSCAN23 Gene

mRNA/cDNA for ZSCAN23 Gene

(6) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZSCAN23 Gene

Zinc finger and SCAN domain containing 23:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN23 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4
SP1:
SP2: - -

Relevant External Links for ZSCAN23 Gene

GeneLoc Exon Structure for
ZSCAN23
ECgene alternative splicing isoforms for
ZSCAN23

Expression for ZSCAN23 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZSCAN23 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZSCAN23 Gene:

ZSCAN23

SOURCE GeneReport for Unigene cluster for ZSCAN23 Gene:

Hs.721841
genes like me logo Genes that share expression patterns with ZSCAN23: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZSCAN23 Gene

Orthologs for ZSCAN23 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN23 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZSCAN23 34 35
  • 99.74 (n)
cow
(Bos Taurus)
Mammalia ZSCAN23 34 35
  • 86.08 (n)
dog
(Canis familiaris)
Mammalia ZSCAN23 34 35
  • 83.65 (n)
oppossum
(Monodelphis domestica)
Mammalia ZSCAN23 35
  • 72 (a)
OneToOne
Species where no ortholog for ZSCAN23 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN23 Gene

ENSEMBL:
Gene Tree for ZSCAN23 (if available)
TreeFam:
Gene Tree for ZSCAN23 (if available)

Paralogs for ZSCAN23 Gene

(427) SIMAP similar genes for ZSCAN23 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZSCAN23 Gene

genes like me logo Genes that share paralogs with ZSCAN23: view

Variants for ZSCAN23 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN23 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000212999 -- 28,442,833(+) GGTGG(C/G)GTGTA intron-variant, utr-variant-5-prime
rs1000367057 -- 28,436,188(+) ATGTT(C/T)CTCCT reference, missense
rs1000398324 -- 28,435,891(+) CTCCA(A/G)ATCCT reference, synonymous-codon
rs1000473775 -- 28,443,818(+) TTTCC(C/T)TGCCG upstream-variant-2KB
rs1000614825 -- 28,443,490(+) TACAA(A/C)GGCCG upstream-variant-2KB, utr-variant-5-prime

Variation tolerance for ZSCAN23 Gene

Gene Damage Index Score: 0.96; 19.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZSCAN23 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZSCAN23

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZSCAN23 Gene

Disorders for ZSCAN23 Gene

Relevant External Links for ZSCAN23

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZSCAN23

No disorders were found for ZSCAN23 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN23 Gene

Publications for ZSCAN23 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3 64
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64

Products for ZSCAN23 Gene

Sources for ZSCAN23 Gene

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