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Aliases for ZSCAN20 Gene

Aliases for ZSCAN20 Gene

  • Zinc Finger And SCAN Domain Containing 20 2 3 5
  • Zinc Finger Protein 31 2 3 4
  • Zinc Finger Protein KOX29 3 4
  • Zinc Finger Protein 360 3 4
  • ZNF360 3 4
  • ZNF31 3 4
  • KOX29 3 4
  • Zinc Finger Protein 31 (KOX 29) 2
  • ZFP-31 3

External Ids for ZSCAN20 Gene

Previous HGNC Symbols for ZSCAN20 Gene

  • ZNF360
  • ZNF31

Previous GeneCards Identifiers for ZSCAN20 Gene

  • GC01P033710
  • GC01P033938
  • GC01P032054

Summaries for ZSCAN20 Gene

GeneCards Summary for ZSCAN20 Gene

ZSCAN20 (Zinc Finger And SCAN Domain Containing 20) is a Protein Coding gene. Diseases associated with ZSCAN20 include intermediate charcot-marie-tooth neuropathy. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and chromatin binding. An important paralog of this gene is ZKSCAN2.

UniProtKB/Swiss-Prot for ZSCAN20 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN20 Gene

Genomics for ZSCAN20 Gene

Regulatory Elements for ZSCAN20 Gene

Promoters for ZSCAN20 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZSCAN20 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZSCAN20 Gene

Chromosome:
1
Start:
33,472,631 bp from pter
End:
33,500,693 bp from pter
Size:
28,063 bases
Orientation:
Plus strand

Genomic View for ZSCAN20 Gene

Genes around ZSCAN20 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN20 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN20 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN20 Gene

Proteins for ZSCAN20 Gene

  • Protein details for ZSCAN20 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17040-ZSC20_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 20
    Protein Accession:
    P17040
    Secondary Accessions:
    • A8K2D0
    • B1ALI4
    • B1ALI5
    • B1ALI6
    • Q6ZN23
    • Q96FA9
    • Q96H84

    Protein attributes for ZSCAN20 Gene

    Size:
    1043 amino acids
    Molecular mass:
    117541 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZSCAN20 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSCAN20 Gene

Proteomics data for ZSCAN20 Gene at MOPED

Post-translational modifications for ZSCAN20 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZSCAN20 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for ZSCAN20

No data available for DME Specific Peptides for ZSCAN20 Gene

Domains & Families for ZSCAN20 Gene

Gene Families for ZSCAN20 Gene

Suggested Antigen Peptide Sequences for ZSCAN20 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P17040

UniProtKB/Swiss-Prot:

ZSC20_HUMAN :
  • Contains 1 SCAN box domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 10 C2H2-type zinc fingers.
Domain:
  • Contains 1 SCAN box domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZSCAN20: view

Function for ZSCAN20 Gene

Molecular function for ZSCAN20 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZSCAN20: view

Animal Model Products

  • Taconic Biosciences Mouse Models for ZSCAN20

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZSCAN20 Gene

Localization for ZSCAN20 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN20 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZSCAN20 Gene COMPARTMENTS Subcellular localization image for ZSCAN20 gene
Compartment Confidence
nucleus 5
mitochondrion 2

No data available for Gene Ontology (GO) - Cellular Components for ZSCAN20 Gene

Pathways & Interactions for ZSCAN20 Gene

SuperPathways for ZSCAN20 Gene

No Data Available

Interacting Proteins for ZSCAN20 Gene

Selected Interacting proteins: P17040-ZSC20_HUMAN for ZSCAN20 Gene via MINT I2D

Symbol External ID(s) Details
SCAND1

Gene Ontology (GO) - Biological Process for ZSCAN20 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN20 Gene

Drugs & Compounds for ZSCAN20 Gene

No Compound Related Data Available

Transcripts for ZSCAN20 Gene

Unigene Clusters for ZSCAN20 Gene

Zinc finger and SCAN domain containing 20:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN20 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8
SP1: -
SP2: - - -
SP3:
SP4:

Relevant External Links for ZSCAN20 Gene

GeneLoc Exon Structure for
ZSCAN20
ECgene alternative splicing isoforms for
ZSCAN20

Expression for ZSCAN20 Gene

mRNA expression in normal human tissues for ZSCAN20 Gene

Protein differential expression in normal tissues from HIPED for ZSCAN20 Gene

This gene is overexpressed in Plasma (27.6), Monocytes (23.4), and Tlymphocyte (18.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for ZSCAN20 Gene



SOURCE GeneReport for Unigene cluster for ZSCAN20 Gene Hs.442705

genes like me logo Genes that share expression patterns with ZSCAN20: view

Protein tissue co-expression partners for ZSCAN20 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZSCAN20 Gene

Orthologs for ZSCAN20 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZSCAN20 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZSCAN20 35
  • 99.62 (n)
  • 99.23 (a)
ZSCAN20 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZSCAN20 36
  • 82 (a)
OneToOne
ZSCAN20 35
  • 85.37 (n)
  • 82.39 (a)
dog
(Canis familiaris)
Mammalia ZSCAN20 35
  • 87.17 (n)
  • 85.28 (a)
ZSCAN20 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zscan20 16
Zscan20 36
  • 77 (a)
OneToOne
Zscan20 35
  • 80.46 (n)
  • 77.27 (a)
oppossum
(Monodelphis domestica)
Mammalia ZSCAN20 36
  • 66 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZSCAN20 36
  • 64 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zscan20 35
  • 80.2 (n)
  • 74.88 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 42 (a)
OneToMany
-- 36
  • 32 (a)
OneToMany
Species with no ortholog for ZSCAN20:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN20 Gene

ENSEMBL:
Gene Tree for ZSCAN20 (if available)
TreeFam:
Gene Tree for ZSCAN20 (if available)

Paralogs for ZSCAN20 Gene

Paralogs for ZSCAN20 Gene

(390) SIMAP similar genes for ZSCAN20 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZSCAN20 Gene

genes like me logo Genes that share paralogs with ZSCAN20: view

Variants for ZSCAN20 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN20 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs34446695 - 33,489,578(-) ACAGT(C/T)GTCTC intron-variant, reference, missense
rs4403594 - 33,491,552(+) TCGGG(G/T)ATAGT reference, missense
rs881884 -- 33,498,788(-) TGGAG(C/G)GTGAA utr-variant-3-prime
rs1359330 -- 33,478,799(+) GTCTA(C/T)ACTGG intron-variant
rs1590431 -- 33,484,025(+) aaggc(A/G)attga intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN20 Gene

Variant ID Type Subtype PubMed ID
nsv834613 CNV Gain 17160897
nsv344 CNV Insertion 18451855

Variation tolerance for ZSCAN20 Gene

Residual Variation Intolerance Score: 14.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.80; 47.53% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZSCAN20 Gene

HapMap Linkage Disequilibrium report
ZSCAN20

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSCAN20 Gene

Disorders for ZSCAN20 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZSCAN20 Gene - From: GeneCards

Disorder Aliases PubMed IDs
intermediate charcot-marie-tooth neuropathy
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for ZSCAN20

Genetic Association Database (GAD)
ZSCAN20
Human Genome Epidemiology (HuGE) Navigator
ZSCAN20
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZSCAN20
genes like me logo Genes that share disorders with ZSCAN20: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZSCAN20 Gene

Publications for ZSCAN20 Gene

  1. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PMID: 23824909) Chen Y. … Ge F. (Mol. Cell Proteomics 2013) 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for ZSCAN20 Gene

Sources for ZSCAN20 Gene

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