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Aliases for ZSCAN2 Gene

Aliases for ZSCAN2 Gene

  • Zinc Finger And SCAN Domain Containing 2 2 3
  • Zinc Finger Protein 29 Homolog 3 4
  • Zinc Finger Protein 854 3 4
  • Zfp-29 3 4
  • ZNF854 3 4
  • ZFP29 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 2 3
  • Zinc Finger Protein 29 2
  • ZSCAN22 6
  • HKR2 6

External Ids for ZSCAN2 Gene

Previous HGNC Symbols for ZSCAN2 Gene

  • ZFP29

Previous GeneCards Identifiers for ZSCAN2 Gene

  • GC15P082945
  • GC15P085144
  • GC15P061230

Summaries for ZSCAN2 Gene

Entrez Gene Summary for ZSCAN2 Gene

  • The protein encoded by this gene contains several copies of zinc finger motif, which is commonly found in transcriptional regulatory proteins. Studies in mice show that this gene is expressed during embryonic development, and specifically in the testis in adult mice, suggesting that it may play a role in regulating genes in germ cells. Alternative splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

GeneCards Summary for ZSCAN2 Gene

ZSCAN2 (Zinc Finger And SCAN Domain Containing 2) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF10.

UniProtKB/Swiss-Prot for ZSCAN2 Gene

  • May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN2 Gene

Genomics for ZSCAN2 Gene

Regulatory Elements for ZSCAN2 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZSCAN2 Gene

84,600,986 bp from pter
84,627,796 bp from pter
26,811 bases
Plus strand

Genomic View for ZSCAN2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZSCAN2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN2 Gene

Proteins for ZSCAN2 Gene

  • Protein details for ZSCAN2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger and SCAN domain-containing protein 2
    Protein Accession:
    Secondary Accessions:
    • A6NG83
    • B2RMQ9
    • Q6ZQY9
    • Q9NWU4

    Protein attributes for ZSCAN2 Gene

    614 amino acids
    Molecular mass:
    69547 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC87537.1; Type=Erroneous translation; Note=Aberrant splicing.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZSCAN2 Gene


neXtProt entry for ZSCAN2 Gene

Proteomics data for ZSCAN2 Gene at MOPED

Post-translational modifications for ZSCAN2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for ZSCAN2 Gene

Domains for ZSCAN2 Gene

Gene Families for ZSCAN2 Gene

  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZSCAN2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q7Z7L9
  • Contains 1 SCAN box domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZSCAN2: view

Function for ZSCAN2 Gene

Molecular function for ZSCAN2 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis.

Gene Ontology (GO) - Molecular Function for ZSCAN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN2: view

Phenotypes for ZSCAN2 Gene

GenomeRNAi human phenotypes for ZSCAN2:
genes like me logo Genes that share phenotypes with ZSCAN2: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZSCAN2 Gene

Localization for ZSCAN2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN2 Gene

Subcellular locations from

Jensen Localization Image for ZSCAN2 Gene COMPARTMENTS Subcellular localization image for ZSCAN2 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZSCAN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZSCAN2: view

Pathways for ZSCAN2 Gene

SuperPathways for ZSCAN2 Gene

No Data Available

Interacting Proteins for ZSCAN2 Gene

Gene Ontology (GO) - Biological Process for ZSCAN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0007275 multicellular organismal development IEA --
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with ZSCAN2: view

No data available for Pathways by source for ZSCAN2 Gene

Transcripts for ZSCAN2 Gene

Unigene Clusters for ZSCAN2 Gene

Zinc finger and SCAN domain containing 2:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZSCAN2

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN2 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3a · 3b · 3c · 3d · 3e · 3f · 3g ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d
SP1: - - - - - - -
SP2: - - -
SP3: - -
SP4: - - - -
SP5: -
SP6: - - - - - -
SP7: - - - - -
SP8: - - -
SP9: - - - - - - - - - - - - -
SP10: - -

Relevant External Links for ZSCAN2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZSCAN2 Gene

mRNA expression in normal human tissues for ZSCAN2 Gene

Protein differential expression in normal tissues for ZSCAN2 Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZSCAN2 Gene

SOURCE GeneReport for Unigene cluster for ZSCAN2 Gene Hs.594023

genes like me logo Genes that share expressions with ZSCAN2: view

Expression partners for ZSCAN2 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZSCAN2 Gene

Orthologs for ZSCAN2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZSCAN2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZSCAN2 35
  • 83.6 (n)
  • 88.6 (a)
  • 88 (a)
(Canis familiaris)
Mammalia ZSCAN2 35
  • 84.12 (n)
  • 90.54 (a)
  • 90 (a)
(Mus musculus)
Mammalia Zscan2 35
  • 85.78 (n)
  • 89.71 (a)
Zscan2 16
Zscan2 36
  • 89 (a)
(Pan troglodytes)
Mammalia LOC100610406 35
  • 99.31 (n)
  • 99.37 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Zscan2 35
  • 85.62 (n)
  • 90.2 (a)
(Monodelphis domestica)
Mammalia ZSCAN2 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia ZSCAN2 36
  • 67 (a)
(Gallus gallus)
Aves -- 36
  • 47 (a)
-- 36
  • 41 (a)
-- 36
  • 45 (a)
-- 36
  • 40 (a)
-- 36
  • 46 (a)
-- 36
  • 45 (a)
-- 36
  • 43 (a)
ZNF302 36
  • 41 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 29 (a)
Species with no ortholog for ZSCAN2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN2 Gene

Gene Tree for ZSCAN2 (if available)
Gene Tree for ZSCAN2 (if available)

Paralogs for ZSCAN2 Gene

Selected SIMAP similar genes for ZSCAN2 Gene using alignment to 9 proteins: Pseudogenes for ZSCAN2 Gene

genes like me logo Genes that share paralogs with ZSCAN2: view

Variants for ZSCAN2 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN2 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs167445 -- 84,614,784(-) ATTCA(A/G)gctgg intron-variant, upstream-variant-2KB
rs172634 -- 84,608,663(+) catta(A/G)aatta intron-variant
rs218319 -- 84,613,931(-) aggca(A/G)aggtg intron-variant, upstream-variant-2KB
rs309426 -- 84,614,160(-) aaaca(A/G)aatta intron-variant, upstream-variant-2KB
rs748455 -- 84,606,344(-) CACTT(A/G)TATTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN2 Gene

Variant ID Type Subtype PubMed ID
nsv428310 CNV Gain+Loss 18775914
esv2672879 CNV Deletion 23128226
dgv2430n71 CNV Gain 21882294
nsv1643 CNV Insertion 18451855

Relevant External Links for ZSCAN2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZSCAN2 Gene

Disorders for ZSCAN2 Gene

No disorders were found for ZSCAN2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZSCAN2 Gene

Publications for ZSCAN2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A zinc finger protein-encoding gene expressed in the post-meiotic phase of spermatogenesis. (PMID: 1937051) Denny P. … Ashworth A. (Gene 1991) 2 3
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZSCAN2 Gene

Sources for ZSCAN2 Gene

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