Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ZSCAN2 Gene

protein-coding   GIFtS: 47
GCID: GC15P085144

Zinc Finger And SCAN Domain Containing 2

(Previous name: zinc finger protein 29)
(Previous symbol: ZFP29)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Zinc Finger And SCAN Domain Containing 21 2     zfp-292
ZFP291 2 3     Zinc Finger And SCAN Domain-Containing Protein 22
Zinc Finger Protein 29 Homolog2 3     Zfp-293
Zinc Finger Protein 8542 3     HKR25
ZNF8542 3     ZSCAN225
Zinc Finger Protein 291     

External Ids:    HGNC: 209941   Entrez Gene: 549932   Ensembl: ENSG000001763717   OMIM: 1652605   UniProtKB: Q7Z7L93   

Export aliases for ZSCAN2 gene to outside databases

Previous GC identifers: GC15P082945 GC15P061230


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for ZSCAN2 Gene:
The protein encoded by this gene contains several copies of zinc finger motif, which is commonly found in
transcriptional regulatory proteins. Studies in mice show that this gene is expressed during embryonic
development, and specifically in the testis in adult mice, suggesting that it may play a role in regulating genes
in germ cells. Alternative splicing of this gene results in several transcript variants encoding different
isoforms. (provided by RefSeq, Jul 2008)

GeneCards Summary for ZSCAN2 Gene:
ZSCAN2 (zinc finger and SCAN domain containing 2) is a protein-coding gene. Diseases associated with ZSCAN2 include cerebellar ataxia, and ataxia. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF436.

UniProtKB/Swiss-Prot: ZSCA2_HUMAN, Q7Z7L9
Function: May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000015.10  NT_010194.18  NC_018926.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZSCAN2 gene promoter:
         E2F-4   E2F-3a   E2F-5   p53   Nkx2-2   Pax-2   E2F-2   Pax-2a   E2F-1   E2F   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZSCAN2 promoter sequence
   Search Chromatin IP Primers for ZSCAN2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZSCAN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q25.2   Ensembl cytogenetic band:  15q25.2   HGNC cytogenetic band: 15q25.2

ZSCAN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZSCAN2 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P085144:  view genomic region     (about GC identifiers)

Start:
85,144,217 bp from pter      End:
85,171,027 bp from pter
Size:
26,811 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ZSCA2_HUMAN, Q7Z7L9 (See protein sequence)
Recommended Name: Zinc finger and SCAN domain-containing protein 2  
Size: 614 amino acids; 69547 Da
Sequence caution: Sequence=BAC87537.1; Type=Erroneous translation; Note=Aberrant splicing;
Secondary accessions: A6NG83 B2RMQ9 Q6ZQY9 Q9NWU4
Alternative splicing: 3 isoforms:  Q7Z7L9-1   Q7Z7L9-3   Q7Z7L9-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZSCAN2: NX_Q7Z7L9

Explore proteomics data for ZSCAN2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZSCAN2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001007073.1  NP_060364.4  NP_870992.2  

    ENSEMBL proteins: 
     ENSP00000446041   ENSP00000410198   ENSP00000442693   ENSP00000445451   ENSP00000439584  
     ENSP00000333895   ENSP00000351257   ENSP00000438628   ENSP00000368663   ENSP00000325123  
     ENSP00000441342   ENSP00000439132   ENSP00000441855   ENSP00000440004  

    ZSCAN2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for ZSCAN2
    OriGene Protein Over-expression Lysate for ZSCAN2
    OriGene Custom MassSpec
    OriGene Custom Protein Services for ZSCAN2
    GenScript Custom Purified and Recombinant Proteins Services for ZSCAN2
    Novus Biologicals ZSCAN2 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZSCAN2

    ZSCAN2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZSCAN2
    Novus Biologicals ZSCAN2 Antibody
    Abcam antibodies for ZSCAN2
    Cloud-Clone Corp. Antibodies for ZSCAN2
    Search ThermoFisher Antibodies for ZSCAN2
    LSBio Antibodies in human, mouse, rat for ZSCAN2

    ZSCAN2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ZSCAN2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZSCAN2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ZSCAN2
    Cloud-Clone Corp. CLIAs for ZSCAN2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    5 InterPro protein domains:
     IPR008916 Retrov_capsid_C
     IPR003309 Tscrpt_reg_SCAN
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q7Z7L9

    ProtoNet protein and cluster: Q7Z7L9

    1 Blocks protein domain: IPB003309 Transcriptional regulator SCAN

    UniProtKB/Swiss-Prot: ZSCA2_HUMAN, Q7Z7L9
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 14 C2H2-type zinc fingers
    Similarity: Contains 1 SCAN box domain


    ZSCAN2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZSCA2_HUMAN, Q7Z7L9
    Function: May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis (By
    similarity)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0046872metal ion binding IEA--
         
    ZSCAN2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ZSCAN2:
     Decreased nuclei size in G2M 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZSCAN2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZSCAN2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZSCAN2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZSCAN2

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat ZSCAN2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZSCAN2 (see all 12):
    hsa-miR-4303 hsa-miR-3128 hsa-miR-26b* hsa-miR-3921 hsa-miR-877* hsa-miR-146a* hsa-miR-153 hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidZSCAN2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZSCAN2
    Predesigned siRNA for gene silencing in human, mouse, rat ZSCAN2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZSCAN2

    Clone
    Products:
         
    OriGene clones in human, mouse for ZSCAN2 (see all 16)
    OriGene ORF clones in mouse, rat for ZSCAN2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZSCAN2 (NM_145238)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZSCAN2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZSCAN2
    Browse ESI BIO Cell Lines and PureStem Progenitors for ZSCAN2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    ZSCA2_HUMAN, Q7Z7L9: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    ZSCAN2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZSCAN2
    Interactions:

        Search GeneGlobe Interaction Network for ZSCAN2

    3 Interacting proteins for ZSCAN2 (Q7Z7L93) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NFE2Q166213I2D: score=1 
    NKD2Q969F23I2D: score=1 
    ZNF513Q8N8E23I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0007275multicellular organismal development IEA--
    GO:0007283spermatogenesis IEA--
    GO:0030154cell differentiation IEA--

    ZSCAN2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZSCAN2 (ZSCA2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for ZSCAN2 gene (3 alternative transcripts): 
    NM_001007072.1  NM_017894.5  NM_181877.3  

    Unigene Cluster for ZSCAN2:

    Zinc finger and SCAN domain containing 2
    Hs.594023  [show with all ESTs]
    Unigene Representative Sequence: NM_181877
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000540936 ENST00000448803(uc010bmz.1 uc002bkr.3 uc010bna.3 uc010uoz.1 uc010uox.1 uc010uoy.1)
    ENST00000546275 ENST00000546148 ENST00000442073 ENST00000334141(uc002bkp.3)
    ENST00000358472 ENST00000502939 ENST00000379358(uc002bkq.3) ENST00000327179
    ENST00000541040 ENST00000538076 ENST00000540894 ENST00000485222 ENST00000303310

    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZSCAN2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZSCAN2 (see all 12):
    hsa-miR-4303 hsa-miR-3128 hsa-miR-26b* hsa-miR-3921 hsa-miR-877* hsa-miR-146a* hsa-miR-153 hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidZSCAN2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZSCAN2
    Predesigned siRNA for gene silencing in human, mouse, rat ZSCAN2
    Clone
    Products:
         
    OriGene clones in human, mouse for ZSCAN2 (see all 16)
    OriGene ORF clones in mouse, rat for ZSCAN2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZSCAN2 (NM_145238)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZSCAN2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN2
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ZSCAN2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZSCAN2
      QuantiTect SYBR Green Assays in human, mouse, rat ZSCAN2
      QuantiFast Probe-based Assays in human, mouse, rat ZSCAN2

    Additional mRNA sequence: 

    AK000602.1 AK128624.1 AK131309.1 AK291224.1 AY262259.1 AY279349.1 BC041620.1 BC136342.1 
    BC143992.1 BC143993.1 BC143994.1 

    6 DOTS entries:

    DT.99971134  DT.40288390  DT.452435  DT.40251054  DT.95328190  DT.75101045 

    Selected AceView cDNA sequences (see all 48):

    BE551570 AI962237 NM_181877 NM_017894 AY262259 BX098626 AK128624 AI990578 
    AY279349 AK131309 BP364585 AL109959 BM709573 AA308980 AL703736 BM916609 
    BU733585 BC041620 BX281690 BM557452 BI087298 AK000602 BU628267 BG574871 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN2 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3a · 3b · 3c · 3d · 3e · 3f · 3g ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d
    SP1:                          -     -     -     -                                         -     -     -                           
    SP2:                          -     -     -                                                                                       
    SP3:                          -     -                                                                                             
    SP4:                          -     -     -     -                                                                                 
    SP5:                          -                                                                                                   


    ECgene alternative splicing isoforms for ZSCAN2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    ZSCAN2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGCCTGTGC
    ZSCAN2 Expression
    About this image

    ZSCAN2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZSCAN2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.594023
        Custom PCR Arrays for ZSCAN2
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ZSCAN2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZSCAN2
    QuantiTect SYBR Green Assays in human, mouse, rat ZSCAN2
    QuantiFast Probe-based Assays in human, mouse, rat ZSCAN2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for ZSCAN2 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zscan21 , 5 zinc finger and SCAN domain containing 21, 5 85.78(n)1
    89.71(a)1
      7 (45.71 cM)5
    226911  NM_009553.21  NP_033579.11 
     808609205 
    chicken
    (Gallus gallus)
    Aves --
    --
    (see all 8)
    Uncharacterized protein
    (see all 8)
    47(a)
    46(a)
    (see all 8)
    many ↔ many
    many ↔ many
    (see all 8)
    18(15432-16889)
    JH375242.1(146619-147632)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    29(a)
    many ↔ many
    2(189201393-189219330)
    African clawed frog
    (Xenopus laevis)
    Amphibia X06021.12   -- 75.39(n)    X06021.1 
    rainbow trout
    (Oncorhynchus mykiss)
    Actinopterygii BX087510.12   -- 75.25(n)    BX087510.1 


    ENSEMBL Gene Tree for ZSCAN2 (if available)
    TreeFam Gene Tree for ZSCAN2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for ZSCAN2 gene
    ZNF4362  ZNF1802  ZNF3222  ZNF712  ZNF5722  ZFP22  ZKSCAN72  ZNF6782  
    ZNF7742  ZNF102  ZFP372  ZNF3292  ZNF8522  ZNF5442  ZFP32  ZNF6062  
    ZNF5022  ZNF8352  
    Selected SIMAP similar genes for ZSCAN2 using alignment to 9 protein entries:     ZSCA2_HUMAN (see all proteins) (see all similar genes):
    ZNF818P    ZNF78L1    kr-znf3    DKFZp686M04222    ZFP41    ZNF182
    ZNF197    DKFZp666C237    ZNF146    ZNF852    DKFZp313M0722    DKFZp666M039
    ZFS-1    ZFS-5    ZFS-6    ZNF180    ZNF271    ZNF323

    ZSCAN2 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for ZSCAN2
    PGOHUM00000244695 PGOHUM00000260157 PGOHUM00000233648


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for ZSCAN2 (see all 578)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1445414721,2
    --85142259(+) CATCCC/TCAGCC 3 -- us2k10--------
    rs765139901,2
    C,F--85142331(+) AAACCC/TATCTT 3 -- us2k11Minor allele frequency- T:0.02WA 118
    rs1480390011,2
    --85142426(+) TCAGGC/TTGGCC 3 -- us2k10--------
    rs1417731861,2
    --85142435(+) CCTGGA/TGGTGG 3 -- us2k10--------
    rs1505902241,2
    --85142479(+) AGATGC/TTACCA 3 -- us2k10--------
    rs1914449521,2
    --85142483(+) GCTACC/TAGGGT 3 -- us2k10--------
    rs37621681,2
    C,F,H--85142647(-) CAAATT/GTGTTA 3 -- us2k118Minor allele frequency- G:0.21NS EA NA CSA WA 2342
    rs1397920451,2
    C--85142677(+) TTTCTA/GTATTT 3 -- us2k10--------
    rs37621671,2
    C--85142959(-) CCGGCA/GTGCGC 3 -- us2k10--------
    rs1828230701,2
    --85143006(+) CACTTC/GATCCG 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZSCAN2 (85144217 - 85171027 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ZSCAN2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2672879CNV Deletion23128226
    nsv1643CNV Insertion18451855
    dgv2430n71CNV Gain21882294
    nsv428310CNV Gain+Loss18775914

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZSCAN2
    DNA2.0 Custom Variant and Variant Library Synthesis for ZSCAN2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 165260    OMIM disorders: --

    2 diseases for ZSCAN2:    About MalaCards
    cerebellar ataxia    ataxia


    ZSCAN2 for disorders           About GeneDecksing


    Export disorders for ZSCAN2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ZSCAN2 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with ZSCAN2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. A zinc finger protein-encoding gene expressed in the post-meiotic phase of spermatogenesis. (PubMed id 1937051)1, 3 Denny P. and Ashworth A. (Gene 1991)
    4. The functional interactome landscape of the human histone deacetylase family. (PubMed id 23752268)1 Joshi P....Cristea I.M. (Mol. Syst. Biol. 2013)
    5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    6. CAMOS, a nonprogressive, autosomal recessive, congenital cerebellar ataxia, is caused by a mutant zinc-finger protein, ZNF592. (PubMed id 20531441)1 Nicolas E....Delague V. (Eur. J. Hum. Genet. 2010)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    9. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (Nature 2006)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 54993 HGNC: 20994 AceView: ZFP29 Ensembl:ENSG00000176371 euGenes: HUgn54993
    ECgene: ZSCAN2 H-InvDB: ZSCAN2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ZSCAN2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ZSCAN2 gene:
    Search GeneIP for patents involving ZSCAN2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ZSCAN2  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for ZSCAN2  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ZSCAN2  
     OriGene qSTAR qPCR primer pairs in human, mouse for ZSCAN2   OriGene Purified Protein for ZSCAN2  
     OriGene ORF clones in mouse, rat for ZSCAN2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZSCAN2   OriGene Custom Protein Services for ZSCAN2  

     
     
     Block miRNA regulation of human, mouse, rat ZSCAN2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ZSCAN2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZSCAN2 Predesigned siRNA for gene silencing in human, mouse, rat ZSCAN2
     QuantiFast Probe-based Assays in human, mouse, rat ZSCAN2 QuantiTect SYBR Green Assays in human, mouse, rat ZSCAN2
     Custom PCR Arrays for ZSCAN2 Search Chromatin IP Primers for ZSCAN2
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZSCAN2  Search GeneGlobe Interaction Network for ZSCAN2
     Regulatory tfbs in ZSCAN2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for ZSCAN2 GenScript cDNA clones with any tag delivered in your preferred vector for ZSCAN2
     GenScript Custom Assay Services for ZSCAN2 GenScript Custom overexpressing Cell Line Services for ZSCAN2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ZSCAN2 (ZSCA2)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ZSCAN2 antibodies
     ZSCAN2 proteins
     Antibodies for ZSCAN2
     See all of Abcam's Antibodies, Kits and Proteins for ZSCAN2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for ZSCAN2
     Antibodies for ZSCAN2
     ELISAs for ZSCAN2
     CLIAs for ZSCAN2



     Browse ESI BIO Cell Lines and PureStem Progenitors for ZSCAN2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN2
     SwitchGear 3'UTR luciferase reporter plasmids for ZSCAN2
     SwitchGear Promoter luciferase reporter plasmids for ZSCAN2
     Search ThermoFisher Antibodies for ZSCAN2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN2
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZSCAN2
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZSCAN2
     LSBio Antibodies in human, mouse, rat for ZSCAN2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZSCAN2 gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4