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Aliases for ZSCAN16 Gene

Aliases for ZSCAN16 Gene

  • Zinc Finger And SCAN Domain Containing 16 2 3 5
  • Zinc Finger Protein 392 2 3 4
  • Zinc Finger Protein 435 2 3 4
  • ZNF392 3 4
  • ZNF435 3 4
  • Zinc Finger And SCAN Domain-Containing Protein 16 3
  • DJ265C24.3 3

External Ids for ZSCAN16 Gene

Previous HGNC Symbols for ZSCAN16 Gene

  • ZNF392
  • ZNF435

Previous GeneCards Identifiers for ZSCAN16 Gene

  • GC06P028201
  • GC06P028093
  • GC06P027900

Summaries for ZSCAN16 Gene

GeneCards Summary for ZSCAN16 Gene

ZSCAN16 (Zinc Finger And SCAN Domain Containing 16) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZSCAN23.

UniProtKB/Swiss-Prot for ZSCAN16 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN16 Gene

Genomics for ZSCAN16 Gene

Regulatory Elements for ZSCAN16 Gene

Enhancers for ZSCAN16 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G028211 1.4 Ensembl ENCODE 10.5 +88.0 87979 2.2 CREB3L1 FEZF1 SLC30A9 ZNF143 ZNF263 SP3 MEF2D SSRP1 ZNF610 RCOR2 ZNF603P ZKSCAN3 ZKSCAN8 ZKSCAN4 ZSCAN31 NKAPL ZSCAN9 PGBD1 ZSCAN16 ZSCAN12
GH06G028382 1.4 Ensembl ENCODE 10.2 +258.8 258844 1.9 MLX CREB3L1 ZFP64 DMAP1 FEZF1 YBX1 YY1 SLC30A9 ZNF143 ZNF263 ZNF603P ZSCAN31 ZKSCAN3 NKAPL ZKSCAN4 ZSCAN16 ZNF165 ZSCAN12
GH06G028220 1.2 FANTOM5 ENCODE 10.5 +96.1 96139 0.8 HDGF PKNOX1 ATF1 ARNT SIN3A GATA2 CBX5 KDM4B GTF2B ZNF518A ZKSCAN4 ZKSCAN3 ZNF603P NKAPL ZKSCAN8 PGBD1 ZSCAN31 ZSCAN12 ZSCAN16 ZNF165
GH06G028398 1.2 ENCODE 9.6 +274.8 274763 2.5 CREB3L1 FEZF1 DMAP1 YY1 ZNF143 ZNF263 SP3 NFYC MEF2D ZNF610 ZNF603P ZKSCAN3 ZSCAN31 ZKSCAN8 ZKSCAN4 ZSCAN23 COX11P1 OR2E1P TRIM27 GPX5
GH06G028251 1.1 ENCODE 10 +127.7 127743 1.6 HDGF PKNOX1 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZBTB7B YY1 ZNF766 ZNF603P ZSCAN9 PGBD1 ZKSCAN3 ZSCAN31 ZKSCAN8 ZSCAN16 ZSCAN12 ZNF391 ZKSCAN4
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZSCAN16 on UCSC Golden Path with GeneCards custom track

Promoters for ZSCAN16 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000195193 144 1401 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 CBX5 ZNF143 ZNF263 SP3

Genomic Location for ZSCAN16 Gene

Chromosome:
6
Start:
28,124,556 bp from pter
End:
28,130,086 bp from pter
Size:
5,531 bases
Orientation:
Plus strand

Genomic View for ZSCAN16 Gene

Genes around ZSCAN16 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN16 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN16 Gene

Proteins for ZSCAN16 Gene

  • Protein details for ZSCAN16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H4T2-ZSC16_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 16
    Protein Accession:
    Q9H4T2
    Secondary Accessions:
    • Q9H6K2

    Protein attributes for ZSCAN16 Gene

    Size:
    348 amino acids
    Molecular mass:
    40792 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for ZSCAN16 Gene

neXtProt entry for ZSCAN16 Gene

Post-translational modifications for ZSCAN16 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZSCAN16 Gene

No data available for DME Specific Peptides for ZSCAN16 Gene

Domains & Families for ZSCAN16 Gene

Gene Families for ZSCAN16 Gene

Suggested Antigen Peptide Sequences for ZSCAN16 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H4T2

UniProtKB/Swiss-Prot:

ZSC16_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZSCAN16: view

Function for ZSCAN16 Gene

Molecular function for ZSCAN16 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZSCAN16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IEA --
GO:0005515 protein binding IPI --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZSCAN16: view
genes like me logo Genes that share phenotypes with ZSCAN16: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZSCAN16 Gene

Localization for ZSCAN16 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN16 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZSCAN16 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZSCAN16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZSCAN16: view

Pathways & Interactions for ZSCAN16 Gene

SuperPathways for ZSCAN16 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZSCAN16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZSCAN16: view

No data available for Pathways by source and SIGNOR curated interactions for ZSCAN16 Gene

Drugs & Compounds for ZSCAN16 Gene

No Compound Related Data Available

Transcripts for ZSCAN16 Gene

mRNA/cDNA for ZSCAN16 Gene

Unigene Clusters for ZSCAN16 Gene

Zinc finger and SCAN domain containing 16:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN16 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c
SP1: - -
SP2:
SP3: -
SP4: -

Relevant External Links for ZSCAN16 Gene

GeneLoc Exon Structure for
ZSCAN16
ECgene alternative splicing isoforms for
ZSCAN16

Expression for ZSCAN16 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZSCAN16 Gene

Protein differential expression in normal tissues from HIPED for ZSCAN16 Gene

This gene is overexpressed in Serum (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZSCAN16 Gene



Protein tissue co-expression partners for ZSCAN16 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZSCAN16 Gene:

ZSCAN16

SOURCE GeneReport for Unigene cluster for ZSCAN16 Gene:

Hs.656641
genes like me logo Genes that share expression patterns with ZSCAN16: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZSCAN16 Gene

Orthologs for ZSCAN16 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN16 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZSCAN16 34 35
  • 99.43 (n)
cow
(Bos Taurus)
Mammalia ZSCAN16 34 35
  • 89.18 (n)
dog
(Canis familiaris)
Mammalia ZSCAN16 34 35
  • 84.1 (n)
oppossum
(Monodelphis domestica)
Mammalia ZSCAN16 35
  • 66 (a)
OneToOne
Species where no ortholog for ZSCAN16 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN16 Gene

ENSEMBL:
Gene Tree for ZSCAN16 (if available)
TreeFam:
Gene Tree for ZSCAN16 (if available)

Paralogs for ZSCAN16 Gene

(355) SIMAP similar genes for ZSCAN16 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZSCAN16 Gene

genes like me logo Genes that share paralogs with ZSCAN16: view

Variants for ZSCAN16 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN16 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs750071607 A colorectal cancer sample 28,126,805(+) AAGAC(A/G)GGACA intron-variant, reference, missense
rs1000183590 -- 28,128,381(+) GACAC(-/TTACA)TTACT intron-variant
rs1000361029 -- 28,128,516(+) AGTAG(C/G)CTTGC intron-variant
rs1000818028 -- 28,129,013(+) CCACC(C/T)ATGTT intron-variant
rs1001466489 -- 28,122,498(+) AAGGT(C/T)GATTG nc-transcript-variant, upstream-variant-2KB

Variation tolerance for ZSCAN16 Gene

Residual Variation Intolerance Score: 84.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.38; 42.14% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZSCAN16 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZSCAN16

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZSCAN16 Gene

Disorders for ZSCAN16 Gene

Relevant External Links for ZSCAN16

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZSCAN16

No disorders were found for ZSCAN16 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZSCAN16 Gene

Publications for ZSCAN16 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 64
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64

Products for ZSCAN16 Gene

Sources for ZSCAN16 Gene

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