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Aliases for ZSCAN12 Gene

Aliases for ZSCAN12 Gene

  • Zinc Finger And SCAN Domain Containing 12 2 3 5
  • Zinc Finger Protein 305 2 3 4
  • Zinc Finger Protein 96 2 3 4
  • ZNF305 3 4
  • ZNF96 3 4
  • DJ29K1.2 3
  • KIAA0426 4
  • ZNF29K1 3
  • ZFP96 3

External Ids for ZSCAN12 Gene

Previous HGNC Symbols for ZSCAN12 Gene

  • ZNF305
  • ZNF96

Previous GeneCards Identifiers for ZSCAN12 Gene

  • GC06M028456
  • GC06M028152

Summaries for ZSCAN12 Gene

GeneCards Summary for ZSCAN12 Gene

ZSCAN12 (Zinc Finger And SCAN Domain Containing 12) is a Protein Coding gene. Diseases associated with ZSCAN12 include Uterine Benign Neoplasm. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZSCAN16.

UniProtKB/Swiss-Prot for ZSCAN12 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN12 Gene

Genomics for ZSCAN12 Gene

Regulatory Elements for ZSCAN12 Gene

Enhancers for ZSCAN12 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZSCAN12 on UCSC Golden Path with GeneCards custom track

Promoters for ZSCAN12 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZSCAN12 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZSCAN12 Gene

28,378,821 bp from pter
28,399,767 bp from pter
20,947 bases
Minus strand

Genomic View for ZSCAN12 Gene

Genes around ZSCAN12 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZSCAN12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZSCAN12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN12 Gene

Proteins for ZSCAN12 Gene

  • Protein details for ZSCAN12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger and SCAN domain-containing protein 12
    Protein Accession:
    Secondary Accessions:
    • O43724

    Protein attributes for ZSCAN12 Gene

    604 amino acids
    Molecular mass:
    70222 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA24856.2; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZSCAN12 Gene

Proteomics data for ZSCAN12 Gene at MOPED

Post-translational modifications for ZSCAN12 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZSCAN12 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZSCAN12 Gene

Domains & Families for ZSCAN12 Gene

Gene Families for ZSCAN12 Gene

Suggested Antigen Peptide Sequences for ZSCAN12 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 SCAN box domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 11 C2H2-type zinc fingers.
  • Contains 1 SCAN box domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZSCAN12: view

Function for ZSCAN12 Gene

Molecular function for ZSCAN12 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZSCAN12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ZSCAN12: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZSCAN12 Gene

Localization for ZSCAN12 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN12 Gene

Subcellular locations from

Jensen Localization Image for ZSCAN12 Gene COMPARTMENTS Subcellular localization image for ZSCAN12 gene
Compartment Confidence
nucleus 5
cytosol 3
cytoskeleton 2

No data available for Gene Ontology (GO) - Cellular Components for ZSCAN12 Gene

Pathways & Interactions for ZSCAN12 Gene

SuperPathways for ZSCAN12 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZSCAN12 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZSCAN12 Gene

Drugs & Compounds for ZSCAN12 Gene

No Compound Related Data Available

Transcripts for ZSCAN12 Gene

Unigene Clusters for ZSCAN12 Gene

Zinc finger and SCAN domain containing 12:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN12 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b
SP1: - -
SP2: -
SP4: -
SP5: - - -

Relevant External Links for ZSCAN12 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZSCAN12 Gene

mRNA expression in normal human tissues for ZSCAN12 Gene

Protein differential expression in normal tissues from HIPED for ZSCAN12 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZSCAN12 Gene

SOURCE GeneReport for Unigene cluster for ZSCAN12 Gene Hs.134816

genes like me logo Genes that share expression patterns with ZSCAN12: view

Protein tissue co-expression partners for ZSCAN12 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZSCAN12 Gene

Orthologs for ZSCAN12 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZSCAN12 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZSCAN12 35
  • 88.74 (n)
  • 84.51 (a)
ZSCAN12 36
  • 79 (a)
(Canis familiaris)
Mammalia ZSCAN12 35
  • 84.55 (n)
  • 80.13 (a)
ZSCAN12 36
  • 75 (a)
(Mus musculus)
Mammalia Zscan12 35
  • 78.25 (n)
  • 69.48 (a)
Zscan12 16
Zscan12 36
  • 69 (a)
(Pan troglodytes)
Mammalia ZSCAN12 35
  • 99.4 (n)
  • 99.02 (a)
ZSCAN12 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Zscan12 35
  • 79.16 (n)
  • 69.94 (a)
Species with no ortholog for ZSCAN12:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN12 Gene

Gene Tree for ZSCAN12 (if available)
Gene Tree for ZSCAN12 (if available)

Paralogs for ZSCAN12 Gene

(441) SIMAP similar genes for ZSCAN12 Gene using alignment to 1 proteins: Pseudogenes for ZSCAN12 Gene

genes like me logo Genes that share paralogs with ZSCAN12: view

Variants for ZSCAN12 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN12 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1052213 -- 28,380,600(-) CACAA(A/G)GAAAA nc-transcript-variant, utr-variant-3-prime
rs1052214 -- 28,380,599(-) ACAAG(A/G)AAAAA nc-transcript-variant, utr-variant-3-prime
rs1052215 -- 28,380,381(-) TAAAC(A/C)TGATG nc-transcript-variant, utr-variant-3-prime
rs1361385 -- 28,390,543(-) ATGTA(C/T)GTAAA intron-variant, reference, missense
rs1416918 -- 28,390,558(-) ATAGA(C/G/T)GTGGT intron-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN12 Gene

Variant ID Type Subtype PubMed ID
nsv830620 CNV Loss 17160897
esv2731752 CNV Deletion 23290073
esv2182271 CNV Deletion 18987734

Variation tolerance for ZSCAN12 Gene

Gene Damage Index Score: 8.95; 87.25% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZSCAN12 Gene

Disorders for ZSCAN12 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZSCAN12 Gene - From: DISEASES

Disorder Aliases PubMed IDs
uterine benign neoplasm
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for ZSCAN12

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ZSCAN12: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZSCAN12 Gene

Publications for ZSCAN12 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. (PMID: 9244436) Lee P.L. … Beutler E. (Genomics 1997) 2 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3
  5. Cloning and characterization of a novel zinc finger protein (rZFP96) in the rat corpus luteum. (PMID: 16426687) Lareu R.R. … Dharmarajan A.M. (Biochim. Biophys. Acta 2005) 23

Products for ZSCAN12 Gene

Sources for ZSCAN12 Gene