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ZSCAN10 Gene

protein-coding   GIFtS: 45
GCID: GC16M003138

Zinc Finger And SCAN Domain Containing 10

(Previous name: zinc finger protein 206)
(Previous symbol: ZNF206)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger And SCAN Domain Containing 101 2
Zinc Finger Protein 2061 2 3
ZNF2061 2 3
Zinc Finger And SCAN Domain-Containing Protein 102

External Ids:    HGNC: 129971   Entrez Gene: 848912   Ensembl: ENSG000001301827   UniProtKB: Q96SZ43   

Export aliases for ZSCAN10 gene to outside databases

Previous GC identifers: GC16M003079 GC16M003110


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZSCAN10 Gene:
ZSCAN10 (zinc finger and SCAN domain containing 10) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is MZF1.

UniProtKB/Swiss-Prot: ZSC10_HUMAN, Q96SZ4
Function: Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Can
both activate and /or repress expression of target genes, depending on the context. Specifically binds the
5'-[GA]CGCNNGCG[CT]-3' DNA consensus sequence. Regulates expression of POU5F1/OCT4, ZSCAN4 and ALYREF/THOC4 (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NC_018927.2  NT_010393.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZSCAN10 gene promoter:
         Egr-1   HSF1 (long)   Lmo2   LUN-1   MIF-1   NF-kappaB   Ik-3   NF-kappaB2   HSF1short   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZSCAN10 promoter sequence
   Search Chromatin IP Primers for ZSCAN10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZSCAN10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

ZSCAN10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZSCAN10 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M003138:  view genomic region     (about GC identifiers)

Start:
3,138,891 bp from pter      End:
3,149,318 bp from pter
Size:
10,428 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZSC10_HUMAN, Q96SZ4 (See protein sequence)
Recommended Name: Zinc finger and SCAN domain-containing protein 10  
Size: 725 amino acids; 80387 Da
Subunit: Interacts with POU5F1/OCT4 and SOX2 (By similarity)
Secondary accessions: B3KQD3
Alternative splicing: 2 isoforms:  Q96SZ4-1   Q96SZ4-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZSCAN10: NX_Q96SZ4

Explore proteomics data for ZSCAN10 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZSCAN10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_116194.1  NP_001269344.1  NP_001269345.1  

    ENSEMBL proteins: 
     ENSP00000252463   ENSP00000459520   ENSP00000440047   ENSP00000458879   ENSP00000460473  
     ENSP00000461871   ENSP00000458260  
    Reactome Protein details: Q96SZ4

    ZSCAN10 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ZSCAN10

     
    Search eBioscience for Proteins for ZSCAN10 

    ZSCAN10 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for ZSCAN10 (ZNF206)
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    ZSCAN10 Assay Products:

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    Cloud-Clone Corp. ELISAs for ZSCAN10
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    Search eBioscience for ELISAs for ZSCAN10 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    5 InterPro protein domains:
     IPR008916 Retrov_capsid_C
     IPR003309 Tscrpt_reg_SCAN
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q96SZ4

    ProtoNet protein and cluster: Q96SZ4

    1 Blocks protein domain: IPB003309 Transcriptional regulator SCAN

    UniProtKB/Swiss-Prot: ZSC10_HUMAN, Q96SZ4
    Similarity: Contains 14 C2H2-type zinc fingers
    Similarity: Contains 1 SCAN box domain


    Find genes that share domains with ZSCAN10           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZSC10_HUMAN, Q96SZ4
    Function: Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Can
    both activate and /or repress expression of target genes, depending on the context. Specifically binds the
    5'-[GA]CGCNNGCG[CT]-3' DNA consensus sequence. Regulates expression of POU5F1/OCT4, ZSCAN4 and ALYREF/THOC4 (By
    similarity)

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity ISS--
    GO:0005515protein binding ----
    GO:0043565sequence-specific DNA binding ISS--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZSCAN10           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for ZSCAN10:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e 

         1 MGI phenotypic allele for Zscan10 (no phenotypes)

    Find genes that share phenotypes with ZSCAN10           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZSCAN10
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZSCAN10
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZSCAN10

    miRNA
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    Search for qRT-PCR Assays for microRNAs that regulate ZSCAN10
    SwitchGear 3'UTR luciferase reporter plasmidZSCAN10 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZSCAN10
    Predesigned siRNA for gene silencing in human, mouse, rat ZSCAN10

    Gene Editing
    Products:
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    Clone
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    OriGene clones in human, mouse for ZSCAN10 (see all 5)
    OriGene ORF clones in mouse, rat for ZSCAN10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZSCAN10 (NM_032805)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZSCAN10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN10

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for ZSCAN10 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN10


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZSC10_HUMAN, Q96SZ4: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--

    Find genes that share ontologies with ZSCAN10           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Find genes that share SuperPaths with ZSCAN10           About GenesLikeMe

    Pathways by sourceSee SuperPaths
    Show all pathways


    1 Reactome Pathway for ZSCAN10
        Transcriptional regulation of pluripotent stem cells


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZSCAN10
    Interactions:

        Search GeneGlobe Interaction Network for ZSCAN10

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ZSCAN10 (ENSP000002524634) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NANOGENSP000002293074STRING: ENSP00000229307
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IBA--
    GO:0045892negative regulation of transcription, DNA-templated ISS--

    Find genes that share ontologies with ZSCAN10           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZSCAN10 (ZSC10)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZSCAN10 gene (3 alternative transcripts): 
    NM_032805.1  NM_001282415.1  NM_001282416.1  

    Unigene Cluster for ZSCAN10:

    Zinc finger and SCAN domain containing 10
    Hs.334515  [show with all ESTs]
    Unigene Representative Sequence: AK027455
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000252463(uc002ctv.1 uc002ctw.1 uc002ctx.1) ENST00000575108(uc002cty.1)
    ENST00000538082 ENST00000571903 ENST00000576985 ENST00000572431 ENST00000572548
    ENST00000576483 ENST00000577059 ENST00000573931
    miRNA
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    Block miRNA regulation of human, mouse, rat ZSCAN10 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate ZSCAN10
    SwitchGear 3'UTR luciferase reporter plasmidZSCAN10 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZSCAN10
    Predesigned siRNA for gene silencing in human, mouse, rat ZSCAN10
    Clone
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    OriGene ORF clones in mouse, rat for ZSCAN10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZSCAN10 (NM_032805)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZSCAN10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZSCAN10
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ZSCAN10
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZSCAN10
      QuantiTect SYBR Green Assays in human, mouse, rat ZSCAN10
      QuantiFast Probe-based Assays in human, mouse, rat ZSCAN10

    Additional mRNA sequence: 

    AK027455.1 AK074736.1 BC111367.1 BC114452.1 

    7 DOTS entries:

    DT.102828033  DT.102828030  DT.102828035  DT.99933490  DT.120683298  DT.120683301  DT.120683303 

    21 AceView cDNA sequences:

    NM_032805 AK074736 AK027455 CD634388 BF511528 CD634389 AA206569 CD634386 
    CD634383 CD634384 CD634380 CD634390 CD634382 CD634387 CD634381 AW003251 
    CD634391 CD634379 AA206496 AI971717 CD634385 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN10    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b
    SP1:                                                      
    SP2:              -     -                                 
    SP3:                    -                                 


    ECgene alternative splicing isoforms for ZSCAN10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZSCAN10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGGAGCCCGG
    ZSCAN10 Expression
    About this image


    ZSCAN10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 16 entries
             Line H1 (WA01)
             ESI-017   
     
     NULL (Uncategorized)
             Mesenchymal Progenitor Cells - Passage 2
     
     Epiblast (Early Embryonic Tissues)
             Epiblast Stem Cell line 5
     
     Neural Tube (Nervous System)
             Floor plate-like cells
    ZSCAN10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZSCAN10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.334515
        Custom PCR Arrays for ZSCAN10
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat ZSCAN10
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZSCAN10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ZSCAN10 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zscan101 , 5 zinc finger and SCAN domain containing 101, 5 75.37(n)1
    72.78(a)1
      17 (11.79 cM)5
    3322211  NM_001033425.31  NP_001028597.21 
     236008565 
    zebrafish
    (Danio rerio)
    Actinopterygii AI617093.12   -- 78.34(n)   337732  AI617093.1 


    ENSEMBL Gene Tree for ZSCAN10 (if available)
    TreeFam Gene Tree for ZSCAN10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZSCAN10 gene
    MZF12  
    Selected SIMAP similar genes for ZSCAN10 using alignment to 6 protein entries:     ZSC10_HUMAN (see all proteins) (see all similar genes):
    ZNF18    ZNF818P    ZNF446    ZNF500    ZNF24    ZSCAN31
    ZNF396    ZNF444    ZFS-5    ZNF213    LOC100128510    ZNF167
    ZNF78L1    ZSCAN32    kr-znf3    ZNF410    ZNF826P    ZNF397

    Find genes that share paralogs with ZSCAN10           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZSCAN10 (see all 219)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1892628741,2
    --3138439(+) TCTCCA/CAGGAT 1 -- ds50010--------
    rs1150196671,2
    F--3138472(+) ACCACG/ACCCGG 1 -- ds50011Minor allele frequency- A:0.05WA 118
    rs47863851,2
    C,F,A,H--3138486(+) ATTTTG/TGTATT 1 -- ds50017Minor allele frequency- T:0.38NA WA 250
    rs1813010731,2
    --3138487(+) TTTTGC/GTATTT 1 -- ds50010--------
    rs778283261,2
    C--3138550(+) ACCTCG/ATGATC 1 -- ds50012Minor allele frequency- A:0.00NA 4
    rs1402091051,2
    --3138568(+) GCCTCA/GGCCTC 1 -- ds50010--------
    rs1453670681,2
    C--3138949(+) AAAGCA/TATGCC 1 -- ut310--------
    rs1491870781,2
    --3139036(+) CTCCGA/CTGTGG 1 -- ut310--------
    rs2007640171,2
    --3139048(+) GGACCC/TCGGGT 1 -- ut310--------
    rs752913511,2
    F--3139078(+) TGGCGG/AAAGGC 1 -- ut311Minor allele frequency- A:0.50NA 4

    HapMap Linkage Disequilibrium report for ZSCAN10 (3138891 - 3149318 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for ZSCAN10:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv509589CNV Insertion20534489
    nsv905185CNV Loss21882294
    nsv905170CNV Loss21882294
    dgv2580n71CNV Loss21882294
    nsv833125CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZSCAN10
    DNA2.0 Custom Variant and Variant Library Synthesis for ZSCAN10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZSCAN10 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ZSCAN10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. A transcriptional map of the FMF region. (PubMed id 9653642)1, 3 Bernot A.... Weissenbach J. (Genomics 1998)
    3. Identification of aberrant methylation regions in neuroblastoma by screening of tissue-specific differentially methylated regions. (PubMed id 22911660)1 Sugito K....Nagase H. (amp 2013)
    4. DNA hypomethylation at the ZNF206-exon 5 CpG island associated with neuronal differentiation in mice and development of neuroblastoma in humans. (PubMed id 22011711)1 Kawashima H....Nagase H. (Int. J. Oncol. 2012)
    5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    7. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (Nat. Biotechnol. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Generation and analysis of 280,000 human expressed sequence tags. (PubMed id 8889549)1 Hillier L.D....Marra M. (Genome Res. 1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84891 HGNC: 12997 AceView: ZNF206 Ensembl:ENSG00000130182 euGenes: HUgn84891
    ECgene: ZSCAN10 H-InvDB: ZSCAN10

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ZSCAN10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for ZSCAN10 gene:
    Search GeneIP for patents involving ZSCAN10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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