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Aliases for ZSCAN1 Gene

Aliases for ZSCAN1 Gene

  • Zinc Finger And SCAN Domain Containing 1 2 3
  • Zinc Finger With SCAN Domain 1 2 3
  • Zinc Finger And SCAN Domain-Containing Protein 1 3
  • ZSCAN19 6
  • ZNF915 3
  • ZNF449 6
  • MZF-1 3

External Ids for ZSCAN1 Gene

Summaries for ZSCAN1 Gene

GeneCards Summary for ZSCAN1 Gene

ZSCAN1 (Zinc Finger And SCAN Domain Containing 1) is a Protein Coding gene. GO annotations related to this gene include transcription coactivator activity and sequence-specific DNA binding RNA polymerase II transcription factor activity. An important paralog of this gene is ZSCAN18.

UniProtKB/Swiss-Prot for ZSCAN1 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZSCAN1 Gene

Genomics for ZSCAN1 Gene

Genomic Location for ZSCAN1 Gene

Start:
58,034,032 bp from pter
End:
58,054,631 bp from pter
Size:
20,600 bases
Orientation:
Plus strand

Genomic View for ZSCAN1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZSCAN1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZSCAN1 Gene

Regulatory Elements for ZSCAN1 Gene

Proteins for ZSCAN1 Gene

  • Protein details for ZSCAN1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NBB4-ZSCA1_HUMAN
    Recommended name:
    Zinc finger and SCAN domain-containing protein 1
    Protein Accession:
    Q8NBB4
    Secondary Accessions:
    • Q3B798
    • Q6WLH8
    • Q86WS8

    Protein attributes for ZSCAN1 Gene

    Size:
    408 amino acids
    Molecular mass:
    45286 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZSCAN1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZSCAN1 Gene

Proteomics data for ZSCAN1 Gene at MOPED

Post-translational modifications for ZSCAN1 Gene

No Post-translational modifications

Other Protein References for ZSCAN1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZSCAN1 Gene

Domains for ZSCAN1 Gene

Gene Families for ZSCAN1 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

UniProtKB/Swiss-Prot:

ZSCA1_HUMAN
Domain:
  • Contains 1 SCAN box domain.:
    • Q8NBB4
Similarity:
  • Contains 3 C2H2-type zinc fingers.:
    • Q8NBB4
genes like me logo Genes that share domains with ZSCAN1: view

Function for ZSCAN1 Gene

Molecular function for ZSCAN1 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZSCAN1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity IBA --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity --
GO:0003713 transcription coactivator activity IBA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ZSCAN1: view

Transcription Factor Targeting for ZSCAN1 Gene

Selected GeneGlobe predicted Target genes for ZSCAN1

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA and HOMER Transcription for ZSCAN1 Gene

Localization for ZSCAN1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZSCAN1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZSCAN1 Gene COMPARTMENTS Subcellular localization image for ZSCAN1 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZSCAN1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZSCAN1: view

Pathways for ZSCAN1 Gene

SuperPathways for ZSCAN1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZSCAN1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated --
GO:0006357 regulation of transcription from RNA polymerase II promoter IBA --
GO:0006366 transcription from RNA polymerase II promoter IBA --
genes like me logo Genes that share ontologies with ZSCAN1: view

No data available for Pathways by source for ZSCAN1 Gene

Transcripts for ZSCAN1 Gene

mRNA/cDNA for ZSCAN1 Gene

Unigene Clusters for ZSCAN1 Gene

Zinc finger and SCAN domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZSCAN1 Gene

No ASD Table

Relevant External Links for ZSCAN1 Gene

GeneLoc Exon Structure for
ZSCAN1
ECgene alternative splicing isoforms for
ZSCAN1

Expression for ZSCAN1 Gene

mRNA expression in normal human tissues for ZSCAN1 Gene

mRNA differential expression in normal tissues according to GTEx for ZSCAN1 Gene

This gene is overexpressed in Pituitary (7.6) and Testis (4.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZSCAN1 Gene

SOURCE GeneReport for Unigene cluster for ZSCAN1 Gene Hs.643437

genes like me logo Genes that share expressions with ZSCAN1: view

Orthologs for ZSCAN1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZSCAN1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZSCAN1 36
  • 99.26 (n)
  • 98.53 (a)
ZSCAN1 37
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZSCAN1 36
  • 73.18 (n)
  • 64.72 (a)
ZSCAN1 37
  • 51 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 21 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 28 (a)
OneToMany
Species with no ortholog for ZSCAN1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZSCAN1 Gene

ENSEMBL:
Gene Tree for ZSCAN1 (if available)
TreeFam:
Gene Tree for ZSCAN1 (if available)

Paralogs for ZSCAN1 Gene

Paralogs for ZSCAN1 Gene

Selected SIMAP similar genes for ZSCAN1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZSCAN1: view

Variants for ZSCAN1 Gene

Sequence variations from dbSNP and Humsavar for ZSCAN1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs159870 -- 58,037,998(+) CACCT(C/G)GCGCT reference, synonymous-codon
rs159871 -- 58,038,913(+) CCCCA(C/G)CAGGG intron-variant
rs159872 -- 58,036,081(+) ACACT(A/C)ACGCA intron-variant, utr-variant-5-prime
rs159873 -- 58,036,148(+) TCCCC(A/G)TGGTC intron-variant, utr-variant-5-prime
rs159874 -- 58,037,063(+) CCTGG(C/T)CTCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZSCAN1 Gene

Variant ID Type Subtype PubMed ID
nsv833885 CNV Loss 17160897
nsv912533 CNV Loss 21882294
nsv912534 CNV Loss 21882294

Relevant External Links for ZSCAN1 Gene

HapMap Linkage Disequilibrium report
ZSCAN1

Disorders for ZSCAN1 Gene

No disorders were found for ZSCAN1 Gene.

No data available for UniProtKB/Swiss-Prot for ZSCAN1 Gene

Publications for ZSCAN1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for ZSCAN1 Gene

Sources for ZSCAN1 Gene

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