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Aliases for ZRSR1 Gene

Aliases for ZRSR1 Gene

  • Zinc Finger CCCH-Type, RNA Binding Motif And Serine/Arginine Rich 1 2 3
  • Zinc Finger (CCCH Type), RNA Binding Motif And Serine/Arginine Rich 1 3 5
  • U2(RNU2) Small Nuclear RNA Auxiliary Factor Pseudogene 1 2 3
  • U2 Small Nuclear RNA Auxillary Factor 1-Like 1 2 3
  • U2AF1-RS1 3 4
  • U2AF1RS1 3 4
  • U2AF1L1 3 4
  • U2AFBPL 3 4
  • U2AF1P 3 4
  • CCCH Type Zinc Finger, RNA-Binding Motif And Serine/Arginine Rich Protein 1 4
  • Zinc Finger (CCCH Type), RNA-Binding Motif And Serine/Arginine Rich 1 3
  • U2 Small Nuclear Ribonucleoprotein Auxiliary Factor, Small Subunit 1 3
  • U2(RNU2) Small Nuclear RNA Auxiliary Factor Binding Protein-Like 2
  • U2(RNU2) Small Nuclear RNA Auxiliary Factor 1-Like 1 4
  • ZC3H21 3

External Ids for ZRSR1 Gene

Previous HGNC Symbols for ZRSR1 Gene

  • U2AFBPL
  • U2AF1P
  • U2AF1L1

Previous GeneCards Identifiers for ZRSR1 Gene

  • GC05P112256
  • GC05P112228
  • GC05P107407

Summaries for ZRSR1 Gene

GeneCards Summary for ZRSR1 Gene

ZRSR1 (Zinc Finger CCCH-Type, RNA Binding Motif And Serine/Arginine Rich 1) is a Pseudogene. GO annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is ZRSR2.

Gene Wiki entry for ZRSR1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZRSR1 Gene

Genomics for ZRSR1 Gene

Genomic Location for ZRSR1 Gene

Chromosome:
5
Start:
112,891,422 bp from pter
End:
112,893,097 bp from pter
Size:
1,676 bases
Orientation:
Plus strand

Genomic View for ZRSR1 Gene

Genes around ZRSR1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZRSR1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZRSR1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZRSR1 Gene

No data available for Regulatory Elements for ZRSR1 Gene

Proteins for ZRSR1 Gene

  • Protein details for ZRSR1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q15695-U2AFL_HUMAN
    Recommended name:
    U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1
    Protein Accession:
    Q15695
    Secondary Accessions:
    • B2R901
    • Q13570
    • Q2M3R8

    Protein attributes for ZRSR1 Gene

    Size:
    479 amino acids
    Molecular mass:
    57643 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZRSR1 Gene

Proteomics data for ZRSR1 Gene at MOPED

Post-translational modifications for ZRSR1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZRSR1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ZRSR1 Gene

Domains & Families for ZRSR1 Gene

Suggested Antigen Peptide Sequences for ZRSR1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q15695

UniProtKB/Swiss-Prot:

U2AFL_HUMAN :
  • Contains 1 RRM (RNA recognition motif) domain.
  • Contains 2 C3H1-type zinc fingers.
Domain:
  • Contains 1 RRM (RNA recognition motif) domain.
Similarity:
  • Contains 2 C3H1-type zinc fingers.
genes like me logo Genes that share domains with ZRSR1: view

Function for ZRSR1 Gene

Gene Ontology (GO) - Molecular Function for ZRSR1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003723 RNA binding IEA --
genes like me logo Genes that share ontologies with ZRSR1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZRSR1 Gene

Localization for ZRSR1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZRSR1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZRSR1 Gene COMPARTMENTS Subcellular localization image for ZRSR1 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZRSR1 Gene

Pathways & Interactions for ZRSR1 Gene

SuperPathways for ZRSR1 Gene

No Data Available

Interacting Proteins for ZRSR1 Gene

Gene Ontology (GO) - Biological Process for ZRSR1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZRSR1 Gene

Drugs & Compounds for ZRSR1 Gene

No Compound Related Data Available

Transcripts for ZRSR1 Gene

mRNA/cDNA for ZRSR1 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for ZRSR1 Gene

No ASD Table

Relevant External Links for ZRSR1 Gene

GeneLoc Exon Structure for
ZRSR1
ECgene alternative splicing isoforms for
ZRSR1

Expression for ZRSR1 Gene

mRNA expression in normal human tissues for ZRSR1 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZRSR1 Gene



genes like me logo Genes that share expression patterns with ZRSR1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZRSR1 Gene

Orthologs for ZRSR1 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZRSR1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZRSR1 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 72 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 85 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zrsr1 36
  • 73 (a)
ManyToMany
Zrsr2 36
  • 67 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 71 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 72 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 36
  • 67 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 68 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii zrsr2 36
  • 41 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG3294 36
  • 27 (a)
OneToMany
Species with no ortholog for ZRSR1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZRSR1 Gene

ENSEMBL:
Gene Tree for ZRSR1 (if available)
TreeFam:
Gene Tree for ZRSR1 (if available)

Paralogs for ZRSR1 Gene

Paralogs for ZRSR1 Gene

(1) SIMAP similar genes for ZRSR1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZRSR1: view

Variants for ZRSR1 Gene

Variation tolerance for ZRSR1 Gene

Gene Damage Index Score: 15.10; 96.91% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZRSR1 Gene

HapMap Linkage Disequilibrium report
ZRSR1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for ZRSR1 Gene

Disorders for ZRSR1 Gene

Relevant External Links for ZRSR1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZRSR1

No disorders were found for ZRSR1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZRSR1 Gene

Publications for ZRSR1 Gene

  1. Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1. (PMID: 8586425) Kitagawa K. … Mukai T. (Genomics 1995) 3 4 23 67
  2. Comparative analyses of genomic imprinting and CpG island-methylation in mouse Murr1 and human MURR1 loci revealed a putative imprinting control region in mice. (PMID: 16305817) Zhang Z. … Mukai T. (Gene 2006) 3 23
  3. Mouse U2af1-rs1 is a neomorphic imprinted gene. (PMID: 9001233) Nabetani A. … Mukai T. (Mol. Cell. Biol. 1997) 3 23
  4. Comparative mapping of the imprinted U2afbpL gene on mouse chromosome 11 and human chromosome 5. (PMID: 7956352) Kalcheva I. … Takagi N. (Cytogenet. Cell Genet. 1995) 2 3
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3

Products for ZRSR1 Gene

Sources for ZRSR1 Gene

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