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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ZP2 Gene

protein-coding GIFtS: 55
GCID: GC16M021208

zona pellucida glycoprotein 2 (sperm receptor)

Explore 5 diseases affiliated with
ZP2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Zona Pellucida Glycoprotein 2 (Sperm Receptor)¹ ²		Zona Pellucida Glycoprotein ZP2²
Zona Pellucida Protein A² ³		Zona Pellucida Sperm-Binding Protein 2²
ZPA² ³		Zona Pellucida Glycoprotein 2³
Zp-2² ³

External Ids:	HGNC: 13188¹	Entrez Gene: 7783²	Ensembl: ENSG00000103310⁷	OMIM: 182888⁵	UniProtKB: Q05996³

Export aliases for ZP2 gene to outside databases

Previous GC identifers: GC16M020617 GC16M021217 GC16M021175 GC16M021116 GC16M019743

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ZP2:

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of

three or four glycoproteins with various functions during fertilization and preimplantation development. The protein

encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and

penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a

conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that

furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the

zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on

mouse studies. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ZP2_HUMAN, Q05996

Function: The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome

reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and

ZP4. ZP2 may act as a secondary sperm receptor

Gene Wiki entry for ZP2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000016.9 NC_018927.1 NT_010393.16

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for ZP2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZP2 promoter sequence

Search SABiosciences Chromatin IP Primers for ZP2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZP2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12 Ensembl cytogenetic band: 16p12.2 HGNC cytogenetic band: 16p12

ZP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZP2 gene location

GeneLoc information about chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16M021208: view genomic region (about GC identifiers)

Start:	21,208,773 bp from pter	End:	21,225,831 bp from pter
Size:	17,059 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ZP2_HUMAN, Q05996 (See protein sequence)

Recommended Name: Zona pellucida sperm-binding protein 2 precursor

Size: 745 amino acids; 82357 Da

Subunit: Polymers of ZP2 and ZP3 organized into long filaments cross-linked by ZP1 homodimers (By similarity)

Subcellular location: Processed zona pellucida sperm-binding protein 2: Secreted, extracellular space, extracellular

matrix

Subcellular location: Cell membrane; Single-pass type I membrane protein

Developmental stage: Expressed during the 2-week growth phase of oogenesis, prior to ovulation

Secondary accessions: B2R7J2 Q4VAN9 Q4VAP0

Explore the universe of human proteins at neXtProt for ZP2: NX_Q05996

Post-translational modifications:

Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona

pellucida¹

Proteolytically cleaved in the N-terminal part probably by the metalloendopeptidase ASTL exocytosed from cortical

granules after fertilization, yielding a N-terminal peptide of about 30 kDa which remains covalently attached to the

C-terminal peptide via disulfide bond(s). This cleavage may play an important role in the post-fertilization block to

polyspermy. Additional proteolytically cleavage of the N-terminal peptide of 30 kDa occurs in one-cell and two-cell

embryos (By similarity)¹

Contains disulfide bond(s) (By similarity)¹

N-glycosylated (By similarity)¹

O-glycosylated; contains sulfate-substituted glycans (By similarity)¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q05996

ZP2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_003451.1

ENSEMBL proteins:

ENSP00000458991 ENSP00000460971 ENSP00000219593

Human Recombinant Protein Products for ZP2:

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	Uscn Proteins for ZP2

Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	--	--
GO:0005578	proteinaceous extracellular matrix	IEA	--
GO:0005771	multivesicular body	ISS	--
GO:0005783	endoplasmic reticulum	ISS	--
GO:0005794	Golgi apparatus	ISS	--

ZP2 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ZP2 for domains About GeneDecksing

2 InterPro domains/families:

IPR017977 ZP_dom_CS

IPR001507 ZP_dom

Graphical View of Domain Structure for InterPro Entry Q05996

ProtoNet protein and cluster: Q05996

1 Blocks protein family: IPB001507 Endoglin/CD105 antigen

UniProtKB/Swiss-Prot: ZP2_HUMAN, Q05996

Domain: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida

Similarity: Belongs to the ZP domain family. ZPA subfamily

Similarity: Contains 1 ZP domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: ZP2_HUMAN, Q05996

Function: The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome

reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and

ZP4. ZP2 may act as a secondary sperm receptor

Genatlas biochemistry entry for ZP2:

zona pellucida glycoprotein 2 (sperm receptor)

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--
GO:0015026	coreceptor activity	TAS	8385033
GO:0032190	acrosin binding	IPI	15950651

ZP2 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for ZP2:

Decreased G3BP1 protein expres

4 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Zp2):

cellular

embryogenesis

endocrine/exocrine gland

reproductive system

ZP2 for phenotypes About GeneDecksing

Animal Models:
Mouse knock-out Zp2^tm1Dean for ZP2

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for ZP2

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZP2

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Ovarian Infertility Genes

Ovarian Infertility Genes

1.00

1 BioSystems Pathway for ZP2

Ovarian Infertility Genes

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for ZP2

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

4 Interacting proteins for ZP2 (Q05996^{2, 3} ENSP00000219593⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PLCG1	P19174²^,³, ENSP00000244007⁴	MINT-8113335 I2D: score=3 STRING: ENSP00000244007
SRC	P12931²^,³, ENSP00000350941⁴	MINT-8113323 I2D: score=3 STRING: ENSP00000350941
ACR	P10323³, ENSP00000216139⁴	I2D: score=4 STRING: ENSP00000216139
ZPBP	Q9BS86³, ENSP00000046087⁴	I2D: score=1 STRING: ENSP00000046087

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006828	NOT manganese ion transport	ISS	--
GO:0006886	intracellular protein transport	ISS	--
GO:0007339	binding of sperm to zona pellucida	ISS	--
GO:0060046	NOT regulation of acrosome reaction	IDA	11751269
GO:0060468	prevention of polyspermy	ISS	--

ZP2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZP2
Search CenterWatch for drugs/clinical trials and news about ZP2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ZP2 gene:

NM_003460.1

Unigene Cluster for ZP2:

Zona pellucida glycoprotein 2 (sperm receptor)

Hs.73982 [show with all ESTs]

Unigene Representative Sequence: AK310454

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000574091 ENST00000574002(uc002dii.2 uc010bwn.1) ENST00000573114

ENST00000576162(uc010bwo.3) ENST00000572752 ENST00000219593

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Additional cDNA sequence:

AK293805.1 AK308820.1 AK310454.1 AK313003.1 BC096304.3 BC096305.3 BC096306.1 BC096307.3

M90366.1

2 DOTS entries:

DT.92414863 DT.120686481

3 AceView cDNA sequences:

NM_003460 M90366 AW753370

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for ZP2 About this scheme

ExUns:	1	^	2	^	3	^	4a	·	4b	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13a	·	13b	^	14	^	15	^	16	^	17	^	18	^	19
SP1:							-
SP2:							-																				-
SP3:

ECgene alternative splicing isoforms for ZP2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ZP2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

ZP2 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Ovary

Ovigerous Cord

Ovum

Female Gametocytes, Germ Cells

Ovary

Antral Follicle

Secondary Oocyte

Female Gametocytes, Germ Cells

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 5 LifeMap Cells

Name

Category

ES-J1 (Embryonic Stem Cell)

Early Embryo, Inner Cell Mass

Short-term differentiated embryoid bodies (Derivation of embryo...)

Long-time differentiated EBs (Derivation of embryo...)

Oocytes (Oocyte formation by ...)

See ZP2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZP2

SOURCE GeneReport for Unigene cluster: Hs.73982

UniProtKB/Swiss-Prot: ZP2_HUMAN, Q05996

Tissue specificity: Oocytes

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for ZP2 gene from 4/9 species (see all 9) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Zp2^{1 , 5}	zona pellucida glycoprotein 2^{1, 5}	73.08(n)¹ 61.41(a)¹		7 (64.38 cM)⁵ 22787¹ NM_011775.6¹ NP_035905.1¹ 120132361⁵
chicken (Gallus gallus)	Aves	ZP2¹	zona pellucida glycoprotein 2 (sperm receptor)	56.51(n) 44.81(a)		427006 NM_001039098.1 NP_001034187.1
lizard (Anolis carolinensis)	Reptilia	-- --	--	49(a) 46(a)	many → 1 many → 1	AAWZ02040743(136-6314) AAWZ02037074(568-9275)
African clawed frog (Xenopus laevis)	Amphibia	xlZPA²	vitelline envelope 69/64 kDa glycoprotein	76.58(n)		AF038151.1

ENSEMBL Gene Tree for ZP2 (if available)
TreeFam Gene Tree for ZP2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ZP2 gene

ZP4² ZP1²

2 SIMAP similar genes for ZP2 using alignment to 2 protein entries: ZP2_HUMAN (see all proteins):

ZP4 ZP1

ZP2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 16 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs114162860^1,2	F	--	21208302(+)	`TTGTCT/GTTAGT`	1	--	ds500¹		1		WA	118
rs181760168^1,2		--	21208403(+)	`CTTATA/GTTACT`	1	--	ds500¹		0	--	--	--	--
rs183637486^1,2		--	21208444(+)	`AAAAGA/GAGGGG`	1	--	ds500¹		0	--	--	--	--
rs188046866^1,2		--	21208449(+)	`AAGGGA/GGGTTG`	1	--	ds500¹		0	--	--	--	--
rs145522064^1,2		--	21208544(+)	`GCTATA/CGCTAA`	1	--	ds500¹		0	--	--	--	--
rs147722884^1,2		--	21208568(+)	`ACTGGG/TAGTGT`	1	--	ds500¹		0	--	--	--	--
rs117444455^1,2	F	--	21208570(+)	`TGGGAG/ATGTCA`	1	--	ds500¹		1		NA	120
rs142600313^1,2		--	21208632(+)	`ACAATC/TATACC`	1	--	ds500¹		0	--	--	--	--
rs181302037^1,2		--	21208665(+)	`ATATAC/TAAATC`	1	--	ds500¹		0	--	--	--	--
rs144932026^1,2		--	21208745(+)	`AATCT-/TAATAAGA`	1	--	ds500¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ZP2 (21208773 - 21225831 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZP2
2 CNVs: 4931 35366

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZP2

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ZP2 for disorders           About GeneDecksing

OMIM gene information: 182888    OMIM disorders: --

5 diseases for ZP2:    About MalaCards

acheiropody oophoritis syndactyly polydactyly

infertility

4 diseases from the University of Copenhagen DISEASES database for ZP2:

Polydactyly Oophoritis Acheiropody Infertility

Export disorders for ZP2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ZP2 gene, integrated from 9 sources (see all 58):
(articles sorted by number of sources associating them with ZP2)

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Conservation of mammalian secondary sperm receptor genes enables the promoter of the human gene to function in mouse oocytes. (PubMed id 8385033)^{1, 2, 3, 9} Liang L.-F. and Dean J. (1993)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PubMed id 10493829)^{1, 2} Loftus B.J.... Adams M.D. (1999)
Localization and functional importance of a conserved zona pellucida 2 protein domain in the human and bovine ovary using monoclonal anti-ZP2 peptide antibodies. (PubMed id 14511786)^{1, 9} Hinsch E....Hinsch K.D. (2003)
Expression of recombinant human zona pellucida protein 2 and its binding capacity to spermatozoa. (PubMed id 10570015)^{1, 9} Tsubamoto H....Koyama K. (1999)
Detection of zona pellucida proteins during human folliculogenesis. (PubMed id 18033806)^{1, 9} Gook D.A....Martic M. (2008)
Biological effects of recombinant human zona pellucida proteins on sperm function. (PubMed id 16407501)^{1, 9} Caballero-Campo P....Gerton G.L. (2006)
Binding of recombinant human proacrosin/acrosin to zona pellucida (ZP) glycoproteins. I. Studies with recombinant human ZPA, ZPB, and ZPC. (PubMed id 15950651)^{1, 9} Furlong L.I....Vazquez-Levin M.H. (2005)
Proteolytic processing of human zona pellucida proteins. (PubMed id 11804956)^{1, 9} Kiefer S.M. and Saling P. (2002)
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)¹ Wu C....Li S.S. (2007)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 7783	HGNC: 13188	AceView: ZP2	Ensembl:ENSG00000103310	euGenes: HUgn7783
ECgene: ZP2	H-InvDB: ZP2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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Name	Description
PharmGKB entry for ZP2	Pharmacogenomics, SNPs, Pathways

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Patent Information for ZP2 gene:
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ZP2 Gene

zona pellucida glycoprotein 2 (sperm receptor)

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ZP2 Gene

zona pellucida glycoprotein 2 (sperm receptor)

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