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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNRD1 Gene

protein-coding   GIFtS: 53
GCID: GC06P030026

zinc ribbon domain containing 1

(Previous names: zinc ribbon domain containing, 1 )
 Explore 14 diseases affiliated with
ZNRD1 via our new
 Human Malady Compendium 
Biological research products
for ZNRD1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Zinc Ribbon Domain Containing 11 2     Zinc Ribbon Domain Containing, 11
HTEX-61 2     Rpa122
HZR141     TEX62
Tctex-61     DNA-Directed RNA Polymerase I Subunit RPA122
RPA121 3     RNA Polymerase I Small Specific Subunit Rpa122
Zinc Ribbon Domain-Containing Protein 12 3     Transcription-Associated Zinc Ribbon Protein2

External Ids:    HGNC: 131821   Entrez Gene: 308342   Ensembl: ENSG000000663797   OMIM: 6075255   UniProtKB: Q9P1U03   

Export aliases for ZNRD1 gene to outside databases

Previous GC identifers: GC06P030085 GC06P029799 GC06P030135 GC06P030137


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ZNRD1:
This gene encodes a protein with similarity to the Saccharomyces cerevisiae Rpa12p subunit of RNA polymerase I.
Alternate splicing of this gene results in two transcript variants encoding the same protein. Additional splice
variants have been described, but their full-length sequences have not been determined. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: RPA12_HUMAN, Q9P1U0
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside
triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors

Gene Wiki entry for ZNRD1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  NT_113891.2  NT_167244.1  NT_167245.1  NT_167246.1  NT_167247.1  
NT_167248.1  NT_167249.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNRD1 gene promoter:
         AREB6   Pax-3   AML1a   Bach2   FOXO3a   FOXO3   Nkx2-5   FOXO3b   Arnt   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNRD1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZNRD1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNRD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p22.1   HGNC cytogenetic band: 6p21

ZNRD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNRD1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P030026:  view genomic region     (about GC identifiers)

Start:
30,026,676 bp from pter      End:
30,032,686 bp from pter
Size:
6,011 bases      Orientation:
plus strand

6/7 alternative locations (see all 7):
Chr6+,ALT_REF_LOCI_3 30,017,009-30,034,051      Chr6+,ALT_REF_LOCI_4 29,947,292-29,950,937      Chr6+,ALT_REF_LOCI_2 30,016,578-30,061,770     
Chr6+,ALT_REF_LOCI_6 30,016,279-30,057,850      Chr6+,ALT_REF_LOCI_5 30,022,360-30,026,007      Chr6+,ALT_REF_LOCI_1 29,963,516-29,977,820     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RPA12_HUMAN, Q9P1U0 (See protein sequence)
Recommended Name: DNA-directed RNA polymerase I subunit RPA12  
Size: 126 amino acids; 13904 Da
Subunit: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits (By similarity)
Subcellular location: Nucleus, nucleolus (By similarity)

Explore the universe of human proteins at neXtProt for ZNRD1: NX_Q9P1U0

ZNRD1 Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).

REFSEQ proteins (2 alternative transcripts): 
NP_055411.1  NP_740753.1  

ENSEMBL proteins: 
 ENSP00000331111   ENSP00000365978   ENSP00000352333   ENSP00000365981  

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Uscn Proteins for ZNRD1

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005730nucleolus IEA--


ZNRD1 for ontologies           About GeneDecksing



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Uscn ELISAs and CLIAs for ZNRD1


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ZNRD1 for domains           About GeneDecksing

3 InterPro domains/families:
 IPR001222 Znf_TFIIS
 IPR012164 DNA-dir_RNApol_C11
 IPR019761 DNA-dir_RNA_pol-M_15_CS

Graphical View of Domain Structure for InterPro Entry Q9P1U0

ProtoNet protein and cluster: Q9P1U0

1 Blocks protein family: IPB001529 DNA-directed RNA polymerase

UniProtKB/Swiss-Prot: RPA12_HUMAN, Q9P1U0
Similarity: Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family
Similarity: Contains 1 TFIIS-type zinc finger


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

     UniProtKB/Swiss-Prot: RPA12_HUMAN, Q9P1U0
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside
triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors

miRNA
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Inhib. RNA
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In Situ Assay
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Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003676nucleic acid binding IEA--
GO:0003899DNA-directed RNA polymerase activity IEA--
GO:0008270zinc ion binding IEA--


ZNRD1 for ontologies           About GeneDecksing


2 GenomeRNAi human phenotypes for ZNRD1:
 Decreased Tat-dependent transc  Decreased p24 protein expressi 


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways  About this table 
See pathways by source

Super-pathwaycontained gene-specific pathways
1Purine metabolism
Purine metabolism1.00
Pyrimidine metabolism0.38
2Metabolism
Metabolic pathways0.38
3RNA Polymerase III Transcription Initiation
RNA polymerase0.35

Pathway sources
See GeneCards unified pathways
Show all pathways



4         Kegg Pathways  (Kegg details for ZNRD1):
    Purine metabolism
Pyrimidine metabolism
Metabolic pathways
RNA polymerase


ZNRD1 for pathways           About GeneDecksing

Interactions:

    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ZNRD1

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

5/12 Interacting proteins for ZNRD1 (Q9P1U02, 3 ENSP000003311114) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
InteractantInteraction Details
GeneCardExternal ID(s)
NONOQ152333, ENSP000002760794I2D: score=4 STRING: ENSP00000276079
CICQ96RK03, ENSP000001607404I2D: score=2 STRING: ENSP00000160740
GFI1BQ5VTD93, ENSP000003447824I2D: score=2 STRING: ENSP00000344782
SACSQ9NZJ43, ENSP000003717294I2D: score=2 STRING: ENSP00000371729
ATXN2Q997003, ENSP000003668434I2D: score=2 STRING: ENSP00000366843
About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006139nucleobase-containing compound metabolic process TAS10662553
GO:0006351transcription, DNA-dependent IEA--


ZNRD1 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

ZNRD1 for compounds           About GeneDecksing

Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZNRD1

6 HMDB Compounds for ZNRD1    About this table
CompoundSynonyms CAS #PubMed Ids
Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
Cytidine triphosphatecytidine 5'-(tetrahydrogen triphosphate) (see all 15)65-47-4--
Guanosine triphosphate5'-GTP (see all 10)86-01-1--
Phosphoric acidacide phosphorique (FRENCH) (see all 20)7664-38-2--
Pyrophosphate(4-)Diphosphoric acid ion (see all 10)14000-31-8--
Uridine triphosphate5'-UTP (see all 7)63-39-8--
3 Novoseek chemical compound relationships for ZNRD1 gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
zinc 53.6 6 10662553 (2), 16373708 (2), 14726695 (1), 15358150 (1)
adriamycin 51.7 6 14726695 (2), 16373708 (1)
vincristine 49.3 4 14726695 (2), 16373708 (1)

Search CenterWatch for drugs/clinical trials and news about ZNRD1 / RPA12 

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ZNRD1 gene (2 alternative transcripts): 
NM_014596.4  NM_170783.2  

Unigene Cluster for ZNRD1:

Zinc ribbon domain containing 1
Hs.57813  [show with all ESTs]
Unigene Representative Sequence: BM557164
6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000471008 ENST00000332435(uc003npa.3) ENST00000376782 ENST00000359374(uc003noz.3)
ENST00000376785 ENST00000463141

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Inhib. RNA
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  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNRD1

Additional cDNA sequence: 

AF024617.1 AF230337.1 AF238320.1 AF238321.1 AK225874.1 BC010898.1 BC050608.1 CR457109.1 
L19693.1 

11 DOTS entries:

DT.100751277  DT.454677  DT.92004981  DT.121346042  DT.121346302  DT.75126766  DT.92424132  DT.95272103 
DT.121346150  DT.92424131  DT.92424130 

11 AceView cDNA sequences:

NM_014596 AF238320 AF238321 NM_170783 AF024616 AF230337 CR457109 BC050608 
BC010898 BC051741 AF024617 

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ZNRD1 (see all 6)    About this scheme

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c
SP1:                                -                                       
SP2:                                                                        
SP3:                          -     -                                       
SP4:                                                                        
SP5:                                -           -                           


ECgene alternative splicing isoforms for ZNRD1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ZNRD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGGGATTAC

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)

About this image
See ZNRD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNRD1

SOURCE GeneReport for Unigene cluster: Hs.57813
    SABiosciences Custom PCR Arrays for ZNRD1
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In Situ
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNRD1

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for ZNRD1 gene from 8/26 species (see all 26)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Znrd11 , 5 zinc ribbon domain containing, 11, 5 80.76(n)1
82.11(a)1
  17 (19.16 cM)5
661361  NM_023162.41  NP_075651.11 
 369543585 
lizard
(Anolis carolinensis)
Reptilia ZNRD16
--
59(a)
1 ↔ 1
2(192732007-192733576)
African clawed frog
(Xenopus laevis)
Amphibia Xl.336132 Xenopus laevis transcribed sequence with weak similarity more 75.93(n)    BJ613134.1 
zebrafish
(Danio rerio)
Actinopterygii BI867463.12   -- 77.55(n)    BI867463.1 
fruit fly
(Drosophila melanogaster)
Insecta RpI121 CG13418-PA 50(n)
43.86(a)
  42563  NM_079715.2  NP_524439.1 
worm
(Caenorhabditis elegans)
Secernentea C15H11.86
DNA-directed RNA polymerase subunit
40(a)
1 ↔ 1
V(14422705-14423346)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G259406
TFIIB zinc-binding protein
31(a)
1 ↔ 1
3(9494697-9496092)
rice
(Oryza sativa)
Liliopsida --
DNA-directed RNA polymerase I subunit RPA12, putat...
30(a)
1 ↔ 1
3(28739704-28742009)


ENSEMBL Gene Tree for ZNRD1 (if available)
TreeFam Gene Tree for ZNRD1 (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/112 NCBI SNPs in ZNRD1 are shown (see all 112    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 6 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1872589491,2
--30027037(+) ACACTA/GTGATA 3 -- us2k1 int10--------
rs1491289991,2
C,--30027355(+) GACAC-/ATAATATC 3 -- us2k1 int10--------
rs37573271,2
C,F,A,H,--30027413(+) ATTAAG/ACCATT 3 -- us2k1 int119Minor allele frequency- A:0.19NS EA WA CSA NA 2344
rs31321301,2
C,F,A,H,--30027452(-) TAAAGC/GAAACA 3 -- us2k1 int115Minor allele frequency- G:0.08NS EA NA WA CSA 782
rs1162504361,2
C,F,--30027613(+) ATCTTT/CACTGA 3 -- us2k1 int11Minor allele frequency- C:0.03WA 118
rs1148703261,2
F,--30027769(+) ACACAC/TAGATA 3 -- int1 us2k11Minor allele frequency- T:0.03WA 118
rs1154390961,2
F,--30027790(+) AAAACT/CGTCTA 3 -- us2k1 int11Minor allele frequency- C:0.03WA 118
rs31321291,2
C,F,H,--30027860(-) TATCAC/TTTAAC 3 -- int1 us2k127Minor allele frequency- T:0.03NS EA NA WA CSA 2287
rs1918814741,2
--30027885(+) TCAGCA/CGTTTG 3 -- us2k1 int10--------
rs802675051,2
C--30027916(+) TATGGA/CGTTCT 3 -- us2k1 int10--------

HapMap Linkage Disequilibrium report for ZNRD1 (30026676 - 30032686 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for ZNRD1: --

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNRD1
DNA2.0 Custom Variant and Variant Library Synthesis for ZNRD1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ZNRD1 for disorders           About GeneDecksing

OMIM gene information: 607525    OMIM disorders: --

14 diseases for ZNRD1:    About MalaCards
esophageal squamous cell carcinoma    systemic lupus erythematosus    squamous cell carcinoma    lupus erythematosus
gestational diabetes    stomach cancer    gastric cancer    esophagitis
gastric adenocarcinoma    esophageal cancer    adenocarcinoma    ataxia
carcinoma    leukemia

1 Novoseek disease relationship for ZNRD1 gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
gastric cancer 59.6 17 15358150 (5), 14726695 (4), 16609701 (3), 15662122 (2) (see all 5)

Human Genome Epidemiology (HuGE) Navigator: ZNRD1 (10 documents)

Export disorders for ZNRD1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for ZNRD1 gene, integrated from 9 sources (see all 33):
(articles sorted by number of sources associating them with ZNRD1)
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  1. A new zinc ribbon gene (ZNRD1) is cloned from the human MHC class I region. (PubMed id 10662553)1, 2, 3, 9 Fan W.... Lennon G. (2000)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
  4. Systematic sequencing of the human HLA-A/HLA-F region: establishment of a cosmid contig and identification of a new gene cluster within 37 kb of sequence. (PubMed id 8938444)1, 3 Lepourcelet M.... Mosser J. (1996)
  5. Overexpression of ZNRD1 promotes multidrug-resistant phenotype of gastric cancer cells through upregulation of P-glycoprotein. (PubMed id 14726695)1, 9 Shi Y....Fan D. (2004)
  6. Suppression of the cell proliferation in stomach cancer cells by the ZNRD1 gene. (PubMed id 15358150)1, 9 Hong L....Fan D. (2004)
  7. ZNRD1 gene suppresses cell proliferation through cell cycle arrest in G1 phase. (PubMed id 15662122)1, 9 Hong L....Fan D. (2005)
  8. A possible association between ZNRD1 and aspirin-induc ed airway bronchoconstriction in a Korean population. (PubMed id 22697009)1 Pasaje C.F....Shin H.D. (2012)
  9. Role of ZNRD1 (zinc ribbon domain-containing 1) in an giogenesis of leukaemia cells. (PubMed id 21080911)1 Hong L....Fan D. (2011)
  10. ZNRD1 (zinc ribbon domain-containing 1) is a host cel lular factor that influences HIV-1 replication and disease progression. (PubMed id 20192730)1 Ballana E....EstAc J.A. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 30834 HGNC: 13182 AceView: ZNRD1 Ensembl:ENSG00000066379 euGenes: HUgn30834
ECgene: ZNRD1 Kegg: 30834 H-InvDB: ZNRD1

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for ZNRD1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
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IP news from LifeMap Sciences, Inc.)
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Patent Information for ZNRD1 gene:
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