Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF99 Gene

Aliases for ZNF99 Gene

  • Zinc Finger Protein 99 2 3 5
  • C19orf9 3 4
  • Zinc Finger Protein ENSP00000375192 3
  • Chromosome 19 Open Reading Frame 9 2
  • Zinc Finger Protein 99 (F8281) 2
  • CTC-451A6.4 3
  • F8281 3

External Ids for ZNF99 Gene

Previous HGNC Symbols for ZNF99 Gene

  • C19orf9

Previous GeneCards Identifiers for ZNF99 Gene

  • GC19U990119
  • GC19M022730
  • GC19M022939
  • GC19M022478

Summaries for ZNF99 Gene

GeneCards Summary for ZNF99 Gene

ZNF99 (Zinc Finger Protein 99) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF729.

UniProtKB/Swiss-Prot for ZNF99 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF99 Gene

Genomics for ZNF99 Gene

Regulatory Elements for ZNF99 Gene

Enhancers for ZNF99 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF99 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF99 Gene

22,752,183 bp from pter
22,784,171 bp from pter
31,989 bases
Minus strand

Genomic View for ZNF99 Gene

Genes around ZNF99 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF99 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF99 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF99 Gene

Proteins for ZNF99 Gene

  • Protein details for ZNF99 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 99
    Protein Accession:
    Secondary Accessions:
    • M0R335

    Protein attributes for ZNF99 Gene

    864 amino acids
    Molecular mass:
    100791 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF99 Gene

Proteomics data for ZNF99 Gene at MOPED

Post-translational modifications for ZNF99 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF99 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF99 Gene

Domains & Families for ZNF99 Gene

Gene Families for ZNF99 Gene

Protein Domains for ZNF99 Gene

Suggested Antigen Peptide Sequences for ZNF99 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 24 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 24 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF99: view

Function for ZNF99 Gene

Molecular function for ZNF99 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF99 Gene

GenomeRNAi human phenotypes for ZNF99:
genes like me logo Genes that share phenotypes with ZNF99: view

Animal Model Products

CRISPR Products

miRNA for ZNF99 Gene

miRTarBase miRNAs that target ZNF99

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF99 Gene

Localization for ZNF99 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF99 Gene

Subcellular locations from

Jensen Localization Image for ZNF99 Gene COMPARTMENTS Subcellular localization image for ZNF99 gene
Compartment Confidence
nucleus 5
cytosol 2
mitochondrion 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for ZNF99 Gene

Pathways & Interactions for ZNF99 Gene

SuperPathways for ZNF99 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF99: view

Pathways by source for ZNF99 Gene

2 Reactome pathways for ZNF99 Gene

Interacting Proteins for ZNF99 Gene

Gene Ontology (GO) - Biological Process for ZNF99 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF99: view

No data available for SIGNOR curated interactions for ZNF99 Gene

Drugs & Compounds for ZNF99 Gene

No Compound Related Data Available

Transcripts for ZNF99 Gene

mRNA/cDNA for ZNF99 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF99 Gene

No ASD Table

Relevant External Links for ZNF99 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF99 Gene

mRNA expression in normal human tissues for ZNF99 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF99 Gene

This gene is overexpressed in Testis (x21.6).

Protein differential expression in normal tissues from HIPED for ZNF99 Gene

This gene is overexpressed in Bone (46.6) and Plasma (19.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF99 Gene

SOURCE GeneReport for Unigene cluster for ZNF99 Gene Hs.568380

genes like me logo Genes that share expression patterns with ZNF99: view

Protein tissue co-expression partners for ZNF99 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF99 Gene

Orthologs for ZNF99 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF99 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC101902880 35
  • 69.68 (n)
  • 56.39 (a)
-- 36
  • 52 (a)
(Canis familiaris)
Mammalia ZNF252 35
  • 57.39 (n)
  • 45.71 (a)
-- 36
  • 50 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 55 (a)
(Mus musculus)
Mammalia A530054K11Rik 36
  • 47 (a)
AA987161 36
  • 43 (a)
Zfp457 36
  • 56 (a)
Zfp458 36
  • 57 (a)
Zfp738 36
  • 52 (a)
Zfp748 36
  • 44 (a)
Zfp759 36
  • 54 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 57 (a)
(Pan troglodytes)
Mammalia ZNF99 36
  • 66 (a)
Species with no ortholog for ZNF99:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF99 Gene

Gene Tree for ZNF99 (if available)
Gene Tree for ZNF99 (if available)

Paralogs for ZNF99 Gene

(503) SIMAP similar genes for ZNF99 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF99: view

Variants for ZNF99 Gene

Sequence variations from dbSNP and Humsavar for ZNF99 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7255780 - 22,759,523(+) TATAA(A/C/G)CTTCT reference, missense
rs34726149 - 22,769,309(+) ATCCC(A/G)AAATG reference, missense
rs7256890 -- 22,762,796(+) caagt(A/G)ggttt intron-variant
rs7257038 -- 22,762,888(+) tcaca(G/T)gatca intron-variant
rs7257092 -- 22,763,099(+) tcacc(A/C)cactt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF99 Gene

Variant ID Type Subtype PubMed ID
esv4924 CNV Complex 18987735
dgv552e201 CNV Deletion 23290073
dgv1066e1 CNV Complex 17122850
esv731 CNV CNV 17122850
esv34340 CNV Loss 17911159
dgv553e201 CNV Deletion 23290073
dgv633e199 CNV Deletion 23128226
nsv436853 CNV Insertion 17901297
nsv525240 CNV Gain 19592680
dgv3814n71 CNV Gain 21882294
dgv3n43 CNV Gain 19587683
esv2751784 CNV Gain 17911159
nsv911451 CNV Gain 21882294
dgv138e55 CNV Gain 17911159
nsv509729 CNV Insertion 20534489
nsv510881 CNV Complex 20534489
nsv911452 CNV Gain 21882294
esv2284083 CNV Deletion 18987734
esv2662471 CNV Deletion 23128226
esv990916 CNV Deletion 20482838
esv1780124 CNV Deletion 17803354
esv2126648 CNV Deletion 18987734
nsv507892 CNV Insertion 20534489
esv1007183 CNV Insertion 20482838
esv1611747 CNV Insertion 17803354

Variation tolerance for ZNF99 Gene

Residual Variation Intolerance Score: 98.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.91; 83.83% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF99 Gene

Disorders for ZNF99 Gene

Relevant External Links for ZNF99

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF99 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF99 Gene

Publications for ZNF99 Gene

  1. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PMID: 8467795) Bellefroid E.J. … Martial J.A. (EMBO J. 1993) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF99 Gene

Sources for ZNF99 Gene