Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF98 Gene

Aliases for ZNF98 Gene

  • Zinc Finger Protein 98 2 3
  • Zinc Finger Protein 739 2 3 4
  • Zinc Finger Protein F7175 3 4
  • ZNF739 3 4
  • F7175 3

External Ids for ZNF98 Gene

Summaries for ZNF98 Gene

GeneCards Summary for ZNF98 Gene

ZNF98 (Zinc Finger Protein 98) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF98 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF98 Gene

Genomics for ZNF98 Gene

Genomic Location for ZNF98 Gene

Start:
22,391,019 bp from pter
End:
22,532,485 bp from pter
Size:
141,467 bases
Orientation:
Minus strand

Genomic View for ZNF98 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF98 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF98 Gene

Regulatory Elements for ZNF98 Gene

Proteins for ZNF98 Gene

  • Protein details for ZNF98 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NK75-ZNF98_HUMAN
    Recommended name:
    Zinc finger protein 98
    Protein Accession:
    A6NK75
    Secondary Accessions:

    Protein attributes for ZNF98 Gene

    Size:
    572 amino acids
    Molecular mass:
    65799 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI10577.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI29811.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for ZNF98 Gene

Proteomics data for ZNF98 Gene at MOPED

Post-translational modifications for ZNF98 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys245 and Lys463

Other Protein References for ZNF98 Gene

No data available for DME Specific Peptides for ZNF98 Gene

Domains for ZNF98 Gene

Gene Families for ZNF98 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF98 Gene

UniProtKB/Swiss-Prot:

ZNF98_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • A6NK75
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • A6NK75
Similarity:
  • Contains 13 C2H2-type zinc fingers.:
    • A6NK75
genes like me logo Genes that share domains with ZNF98: view

Function for ZNF98 Gene

Molecular function for ZNF98 Gene

GENATLAS Biochemistry: zinc finger protein 98,KRAB subfamily
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF98 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF98: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF98 Gene

Localization for ZNF98 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF98 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF98 Gene COMPARTMENTS Subcellular localization image for ZNF98 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF98 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF98: view

Pathways for ZNF98 Gene

SuperPathways for ZNF98 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF98: view

Pathways by source for ZNF98 Gene

2 Reactome pathways for ZNF98 Gene

Interacting Proteins for ZNF98 Gene

Gene Ontology (GO) - Biological Process for ZNF98 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF98: view

Transcripts for ZNF98 Gene

mRNA/cDNA for ZNF98 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF98 Gene

Zinc finger protein 98:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF98 Gene

No ASD Table

Relevant External Links for ZNF98 Gene

GeneLoc Exon Structure for
ZNF98
ECgene alternative splicing isoforms for
ZNF98

Expression for ZNF98 Gene

mRNA expression in normal human tissues for ZNF98 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF98 Gene

This gene is overexpressed in Pancreas (10.0), Testis (5.8), and Brain - Caudate (basal ganglia) (4.0).

SOURCE GeneReport for Unigene cluster for ZNF98 Gene Hs.667355

genes like me logo Genes that share expressions with ZNF98: view

Orthologs for ZNF98 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF98 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 97 (a)
OneToMany
LOC100611724 36
  • 95.5 (n)
  • 91.54 (a)
cow
(Bos Taurus)
Mammalia -- 37
  • 57 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 40 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp71-rs1 37
  • 59 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 41 (a)
ManyToMany
-- 37
  • 51 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 55 (a)
ManyToMany
-- 37
  • 36 (a)
ManyToMany
-- 37
  • 43 (a)
ManyToMany
-- 37
  • 41 (a)
ManyToMany
-- 37
  • 33 (a)
ManyToMany
-- 37
  • 32 (a)
ManyToMany
-- 37
  • 32 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
Species with no ortholog for ZNF98:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF98 Gene

ENSEMBL:
Gene Tree for ZNF98 (if available)
TreeFam:
Gene Tree for ZNF98 (if available)

Paralogs for ZNF98 Gene

Selected SIMAP similar genes for ZNF98 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF98: view

Variants for ZNF98 Gene

Sequence variations from dbSNP and Humsavar for ZNF98 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1368476 -- 22,403,390(-) GTCTT(C/T)GTGGG synonymous-codon, reference
rs1368477 -- 22,403,207(-) tttga(C/T)ctgaa intron-variant
rs1821294 -- 22,403,264(-) ttttt(G/T)ttttt intron-variant
rs1835995 -- 22,401,445(-) ttatt(A/T)ttgtc intron-variant
rs1897612 -- 22,403,674(-) AGAAT(A/G)CATTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF98 Gene

Variant ID Type Subtype PubMed ID
esv4924 CNV Complex 18987735
esv2718335 CNV Deletion 23290073
dgv552e201 CNV Deletion 23290073
dgv1066e1 CNV Complex 17122850
esv731 CNV CNV 17122850
esv34340 CNV Loss 17911159
dgv553e201 CNV Deletion 23290073
dgv633e199 CNV Deletion 23128226
nsv436853 CNV Insertion 17901297
nsv525240 CNV Gain 19592680
dgv3813n71 CNV Gain 21882294
dgv3814n71 CNV Gain 21882294
dgv3n43 CNV Gain 19587683
nsv911441 CNV Gain 21882294
essv3682 CNV CNV 17122850
nsv911446 CNV Loss 21882294
dgv1067e1 CNV Complex 17122850
nsv911447 CNV Loss 21882294
esv2751784 CNV Gain 17911159
esv1314456 CNV Deletion 17803354

Relevant External Links for ZNF98 Gene

HapMap Linkage Disequilibrium report
ZNF98

Disorders for ZNF98 Gene

Relevant External Links for ZNF98

Genetic Association Database (GAD)
ZNF98
genes like me logo Genes that share disorders with ZNF98: view

No data available for UniProtKB/Swiss-Prot for ZNF98 Gene

Publications for ZNF98 Gene

  1. Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial. (PMID: 22331829) Chasman D.I. … Ridker P.M. (Circ Cardiovasc Genet 2012) 3 49
  2. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PMID: 8467795) Bellefroid E.J. … Martial J.A. (EMBO J. 1993) 3 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF98 Gene

Sources for ZNF98 Gene

Back to Top

Content