ZNF93 Gene
protein-coding GIFtS: 43
GCID: GC19P020012
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zinc finger protein 93(Previous names: zinc finger protein 505, zinc finger protein 93 (HTF34)...)
(Previous symbol: ZNF505)
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Aliases
for ZNF93 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 931 2 | | Zinc Finger Protein HTF342 3 | | Zinc Finger Protein 5051 2 3 | | FLJ124881 | | ZNF5051 2 3 | | Zinc Finger Protein 93 (HTF34)1 | | HPF341 2 | | HTF342 | | TF341 2 | | |
Export aliases for ZNF93 gene to outside databasesPrevious GC identifers: GC19U990113 GC19M020417 GC19P019871 GC19P019887 GC19P019805 GC19P019873 GC19P019979 |
Summaries
for ZNF93 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZNF93_HUMAN, P35789Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF93 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF93 gene promoter:
XBP-1 LCR-F1 Evi-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF93
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF93 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p12 Ensembl cytogenetic band: 19p12 HGNC cytogenetic band: 19p12ZNF93 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P020012: view genomic region
(about GC identifiers)
Start:
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20,011,722 bp from pter |
End:
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20,046,384 bp from pter |
Size:
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34,663 bases |
Orientation:
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plus strand |
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Proteins
for ZNF93 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZNF93_HUMAN, P35789 (See
protein sequence)Recommended Name: Zinc finger protein 93 Size: 620 amino acids; 70971 Da
Subcellular location: Nucleus (Probable)
Developmental stage: Expressed early during embryonic development
Sequence caution: Sequence=BAB14093.1; Type=Erroneous initiation;
Secondary accessions: A6NMY2 B9EGT2 Q8N8Q4 Q9H9X5 Q9Y2N8Alternative splicing: 3 isoforms: P35789-1 P35789-2 P35789-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZNF93: NX_P35789
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P35789
ZNF93 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_112495.2
ENSEMBL proteins: ENSP00000467652 ENSP00000468563 ENSP00000467553 ENSP00000467377 ENSP00000342002
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
NAS | -- |
ZNF93 for ontologies About GeneDecksing
ZNF93 Antibody Products:
Assay Products for ZNF93: |
Protein
Domains /
Families
for ZNF93 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF93 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P35789ProtoNet protein and cluster: P35789 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZNF93_HUMAN, P35789Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 17 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF93 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZNF93_HUMAN, P35789Function: May be involved in transcriptional regulation Genatlas biochemistry entry for ZNF93:zinc finger protein 93 (HTF34),KRAB subfamily
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF93
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF93
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF93 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF93 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF93 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF93
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for ZNF93 (ENSP000003420024) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
NAS | -- |
ZNF93 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF93 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF93
Search CenterWatch for drugs/clinical trials and news about ZNF93
|
Transcripts
for ZNF93 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF93 gene (2 alternative transcripts): NM_001004126.1 NM_031218.3 Unigene Cluster for ZNF93: Zinc finger protein 93 Hs.723768 [show with all ESTs]Unigene Representative Sequence: NM_0312187 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000592613 ENST00000591366 ENST00000586021 ENST00000588146 ENST00000592160
ENST00000589903 ENST00000343769(uc002nom.3 uc002non.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF93
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF93
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF93 (NM_031218) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF93 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF93 |
Additional cDNA sequence: AK022550.1 AK096342.1 AK295921.1 BC020837.1 BC038096.1 BC039001.1 BC058821.1 BC070372.1 BC107581.1 BC136718.1 BC136719.1 15 DOTS entries: DT.97858455 DT.302998 DT.96086749 DT.100020145 DT.91744579 DT.95280084 DT.121493003 DT.70105097 DT.99987709 DT.99995515 DT.121492518 DT.102840686 DT.121492640 DT.91640964 DT.95100464 24/26 AceView cDNA sequences (see all 26): BU165449 BX096570 BG390090 BC070372 BX281668 NM_031218 NM_001004126 AI287601 BM761850 BG257405 BC058821 BG289439 BC020837 AK096342 BM800562 AL710992 BI766100 CD637296 CD637297 BC039001 AW946315 CD637295 CD637294 AI378921
GeneLoc Exon Structure
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Expression
for ZNF93 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF93 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ZNF93 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF93
SOURCE GeneReport for Unigene cluster: Hs.723768
SABiosciences Custom PCR Arrays for ZNF93
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF93
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF93 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF93 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF93 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF93 |
Orthologs
for ZNF93 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF93 gene from 1/4 species (see all 4) About this table
ENSEMBL Gene Tree for ZNF93 (if available)
TreeFam Gene Tree for ZNF93 (if available) |
Paralogs
for ZNF93 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF93 gene
- ZNF852 ZNF4932 ZNF4862 ZNF1002 ZNF922 ZNF7322 ZNF1382 ZNF6752
- ZNF5062 ZNF2732 ZNF66P2 ZNF6952 ZNF6262 ZNF6802 ZNF2532 ZNF4792
- ZNF4922 ZNF6822 ZNF6762 ZNF1412 ZNF6812 ZNF6792 ZNF2572 ZNF2542
- ZNF7372 ZNF724P2 ZNF982 ZNF849P2 ZNF7162 ZNF7142 ZNF4292 ZNF4302
- ZNF7302 ZNF6782 ZNF7082 ZNF1172 ZNF1072 ZNF4312 ZNF902
18/518 SIMAP similar genes for ZNF93 using alignment to 6 protein entries: ZNF93_HUMAN (see all proteins)
(see all similar genes):ZNF66 ZNF90 ZNF506 MGC12518 ZNF66P ZNF737
ZNF818P ZNF273 ZNF626 ZNF420 ZNF724P ZNF571
DKFZp313M0722 DKFZp686M04222 ZNF100 ZNF232 ZNF323 smap-7
ZNF93 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ZNF93
PGOHUM00000243108
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Genomic Variants
for ZNF93 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF93 (20011722 - 20046384 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF93: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF93 |
|
Disorders
/ Diseases
for ZNF93 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZNF93 for disorders About MalaCards
ZNF93 for disorders About GeneDecksing
OMIM gene information: 603975
OMIM disorders: --
Human Genome Epidemiology (HuGE) Navigator: ZNF93 (1 document)
Export disorders for ZNF93 gene to outside databases
|
Publications
for ZNF93 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF93 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with ZNF93) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins. (PubMed id 2023909)1, 2, 3 Bellefroid E.J....Martial J.A. (1991)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PubMed id 8467795)1, 3 Bellefroid E.J.... Martial J.A. (1993)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Genome-wide and candidate gene association study of cigarette smoking behaviors. (PubMed id 19247474)1 Caporaso N....Bergen A.W. (2009)
- ZNF93 increases resistance to ET-743 (Trabectedin; Yo ndelis) and PM00104 (Zalypsis) in human cancer cell lines. (PubMed id 19742314)1 Duan Z....Hornicek F.J. (2009)
- Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for ZNF93 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF93 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF93 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF93 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF93 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF93 gene:
Search GeneIP for patents involving ZNF93
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF93 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | Browse OriGene 29mer shRNA kits in GFP-retroviral vector | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF93 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF93 | | OriGene 3'-UTR Clone for ZNF93 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF93 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF93 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF93 | | OriGene Custom Protein Services for ZNF93 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF93 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF93 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF93 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF93 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF93 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF93 |
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 | | | ZNF93 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF93 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF93 |
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