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Aliases for ZNF92 Gene

Aliases for ZNF92 Gene

  • Zinc Finger Protein 92 2 3
  • Zinc Finger Protein HTF12 3 4
  • Zinc Finger Protein 92 (HTF12) 2
  • Epididymis Luminal Protein 203 3
  • HEL-203 3
  • HPF12 3
  • HTF12 3
  • TF12 3

External Ids for ZNF92 Gene

Summaries for ZNF92 Gene

GeneCards Summary for ZNF92 Gene

ZNF92 (Zinc Finger Protein 92) is a Protein Coding gene. Diseases associated with ZNF92 include myocardial stunning. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF92 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF92 Gene

Genomics for ZNF92 Gene

Genomic Location for ZNF92 Gene

Start:
65,373,799 bp from pter
End:
65,401,136 bp from pter
Size:
27,338 bases
Orientation:
Plus strand

Genomic View for ZNF92 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF92 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF92 Gene

Regulatory Elements for ZNF92 Gene

Proteins for ZNF92 Gene

  • Protein details for ZNF92 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q03936-ZNF92_HUMAN
    Recommended name:
    Zinc finger protein 92
    Protein Accession:
    Q03936
    Secondary Accessions:
    • A6NNF9
    • Q8N492
    • Q8NB35

    Protein attributes for ZNF92 Gene

    Size:
    586 amino acids
    Molecular mass:
    68487 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF92 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF92 Gene

Proteomics data for ZNF92 Gene at MOPED

Post-translational modifications for ZNF92 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys97

Other Protein References for ZNF92 Gene

No data available for DME Specific Peptides for ZNF92 Gene

Domains for ZNF92 Gene

Gene Families for ZNF92 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF92 Gene

UniProtKB/Swiss-Prot:

ZNF92_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q03936
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q03936
Similarity:
  • Contains 16 C2H2-type zinc fingers.:
    • Q03936
genes like me logo Genes that share domains with ZNF92: view

Function for ZNF92 Gene

Molecular function for ZNF92 Gene

GENATLAS Biochemistry: zinc finger protein 92 (HTF12),KRAB subfamily
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF92 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity NAS 2023909
GO:0008270 zinc ion binding NAS 2023909
GO:0046872 metal ion binding --
genes like me logo Genes that share ontologies with ZNF92: view

Phenotypes for ZNF92 Gene

GenomeRNAi human phenotypes for ZNF92:
genes like me logo Genes that share phenotypes with ZNF92: view

miRNA for ZNF92 Gene

miRTarBase miRNAs that target ZNF92

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF92 Gene

Localization for ZNF92 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF92 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF92 Gene COMPARTMENTS Subcellular localization image for ZNF92 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF92 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF92: view

Pathways for ZNF92 Gene

SuperPathways for ZNF92 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF92: view

Pathways by source for ZNF92 Gene

2 Reactome pathways for ZNF92 Gene

Gene Ontology (GO) - Biological Process for ZNF92 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF92: view

Transcripts for ZNF92 Gene

Unigene Clusters for ZNF92 Gene

Zinc finger protein 92:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF92 Gene

ExUns: 1 ^ 2 ^ 3a · 3b
SP1:
SP2: -

Relevant External Links for ZNF92 Gene

GeneLoc Exon Structure for
ZNF92
ECgene alternative splicing isoforms for
ZNF92

Expression for ZNF92 Gene

mRNA expression in normal human tissues for ZNF92 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for ZNF92 Gene Hs.9521

genes like me logo Genes that share expressions with ZNF92: view

Orthologs for ZNF92 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF92 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF92 36
  • 99.6 (n)
  • 99.83 (a)
ZNF92 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 56 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 40 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp493 37
  • 61 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 41 (a)
ManyToMany
-- 37
  • 51 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 52 (a)
ManyToMany
-- 37
  • 35 (a)
ManyToMany
-- 37
  • 42 (a)
ManyToMany
-- 37
  • 40 (a)
ManyToMany
-- 37
  • 34 (a)
ManyToMany
-- 37
  • 33 (a)
ManyToMany
-- 37
  • 32 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
Species with no ortholog for ZNF92:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF92 Gene

ENSEMBL:
Gene Tree for ZNF92 (if available)
TreeFam:
Gene Tree for ZNF92 (if available)

Paralogs for ZNF92 Gene

Selected SIMAP similar genes for ZNF92 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZNF92 Gene

genes like me logo Genes that share paralogs with ZNF92: view

Variants for ZNF92 Gene

Sequence variations from dbSNP and Humsavar for ZNF92 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs1237946 -- 65,394,895(-) gccaa(C/G)gcggg intron-variant
rs3846970 -- 65,394,032(-) gacaa(C/T)gtccc intron-variant
rs3846971 -- 65,394,175(-) aggaa(A/C)aatat intron-variant
rs3846972 -- 65,399,999(-) AATTA(G/T)CTTAC utr-variant-3-prime
rs3857680 -- 65,390,398(-) aaaac(C/T)tgaag intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF92 Gene

Variant ID Type Subtype PubMed ID
dgv1147e201 CNV Deletion 23290073
dgv226e55 CNV Loss 17911159
nsv517778 CNV Gain+Loss 19592680
esv2734586 CNV Deletion 23290073
dgv227e55 CNV Loss 17911159
nsv888287 CNV Gain 21882294
dgv1213e199 CNV Deletion 23128226
dgv2088e1 CNV Complex 17122850
dgv228e55 CNV Gain 17911159
nsv7400 OTHER Inversion 18451855
esv33731 CNV Gain+Loss 17666407
nsv435849 CNV Deletion 17901297
dgv7310n71 CNV Gain 21882294
dgv7311n71 CNV Gain+Loss 21882294
dgv7312n71 CNV Loss 21882294
dgv7313n71 CNV Loss 21882294
nsv470266 CNV Gain 18288195
nsv470277 CNV Loss 18288195
dgv818n27 CNV Loss 19166990
dgv819n27 CNV Gain 19166990
dgv8n29 CNV Complex 16826518
nsv464530 CNV Loss 19166990
nsv831016 CNV Loss 17160897
dgv7316n71 CNV Loss 21882294
dgv229e55 CNV Loss 17911159
nsv888310 CNV Gain 21882294
nsv464534 CNV Loss 19166990
dgv7317n71 CNV Gain 21882294
nsv888316 CNV Gain+Loss 21882294
dgv7318n71 CNV Loss 21882294

Relevant External Links for ZNF92 Gene

HapMap Linkage Disequilibrium report
ZNF92

Disorders for ZNF92 Gene

(1) MalaCards Diseases for ZNF92 Gene

Search for ZNF92 Gene in MalaCards »

(1) University of Copenhagen DISEASES for ZNF92 Gene

Relevant External Links for ZNF92

Genetic Association Database (GAD)
ZNF92
Human Genome Epidemiology (HuGE) Navigator
ZNF92
genes like me logo Genes that share disorders with ZNF92: view

No data available for UniProtKB/Swiss-Prot for ZNF92 Gene

Publications for ZNF92 Gene

  1. The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins. (PMID: 2023909) Bellefroid E.J. … Martial J.A. (Proc. Natl. Acad. Sci. U.S.A. 1991) 3 4
  2. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PMID: 8467795) Bellefroid E.J. … Martial J.A. (EMBO J. 1993) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  5. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 49

Products for ZNF92 Gene

Sources for ZNF92 Gene

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