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Aliases for ZNF90 Gene

Aliases for ZNF90 Gene

  • Zinc Finger Protein 90 2 3
  • Zinc Finger Protein HTF9 3 4
  • Zinc Finger Protein 90 (HTF9) 2
  • HTF9 3

External Ids for ZNF90 Gene

Summaries for ZNF90 Gene

GeneCards Summary for ZNF90 Gene

ZNF90 (Zinc Finger Protein 90) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF90 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF90 Gene

Genomics for ZNF90 Gene

Genomic Location for ZNF90 Gene

Start:
20,077,994 bp from pter
End:
20,127,076 bp from pter
Size:
49,083 bases
Orientation:
Plus strand

Genomic View for ZNF90 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF90 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF90 Gene

Regulatory Elements for ZNF90 Gene

Proteins for ZNF90 Gene

  • Protein details for ZNF90 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q03938-ZNF90_HUMAN
    Recommended name:
    Zinc finger protein 90
    Protein Accession:
    Q03938
    Secondary Accessions:
    • B9EH87

    Protein attributes for ZNF90 Gene

    Size:
    601 amino acids
    Molecular mass:
    69058 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF90 Gene

Proteomics data for ZNF90 Gene at MOPED

Post-translational modifications for ZNF90 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys208, Lys339, and Lys342

Other Protein References for ZNF90 Gene

No data available for DME Specific Peptides for ZNF90 Gene

Domains for ZNF90 Gene

Gene Families for ZNF90 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF90 Gene

UniProtKB/Swiss-Prot:

ZNF90_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q03938
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q03938
Similarity:
  • Contains 15 C2H2-type zinc fingers.:
    • Q03938
genes like me logo Genes that share domains with ZNF90: view

Function for ZNF90 Gene

Molecular function for ZNF90 Gene

GENATLAS Biochemistry: zinc finger protein 90 (HTF9),KRAB subfamily
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF90 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity NAS 2023909
GO:0003735 structural constituent of ribosome --
GO:0008270 zinc ion binding NAS 2023909
genes like me logo Genes that share ontologies with ZNF90: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF90 Gene

Localization for ZNF90 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF90 Gene

Gene Ontology (GO) - Cellular Components for ZNF90 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
GO:0005840 ribosome --
genes like me logo Genes that share ontologies with ZNF90: view

Pathways for ZNF90 Gene

SuperPathways for ZNF90 Gene

No Data Available

Interacting Proteins for ZNF90 Gene

Gene Ontology (GO) - Biological Process for ZNF90 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006412 translation --
genes like me logo Genes that share ontologies with ZNF90: view

No data available for Pathways by source for ZNF90 Gene

Transcripts for ZNF90 Gene

mRNA/cDNA for ZNF90 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF90 Gene

Zinc finger protein 90:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF90 Gene

No ASD Table

Relevant External Links for ZNF90 Gene

GeneLoc Exon Structure for
ZNF90
ECgene alternative splicing isoforms for
ZNF90

Expression for ZNF90 Gene

mRNA expression in normal human tissues for ZNF90 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF90 Gene

SOURCE GeneReport for Unigene cluster for ZNF90 Gene Hs.55304

genes like me logo Genes that share expressions with ZNF90: view

Orthologs for ZNF90 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF90 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF90 36
  • 99.22 (n)
  • 98.84 (a)
ZNF90 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 53 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 38 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp386 37
  • 33 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 41 (a)
ManyToMany
-- 37
  • 47 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 54 (a)
ManyToMany
-- 37
  • 39 (a)
ManyToMany
-- 37
  • 47 (a)
ManyToMany
-- 37
  • 39 (a)
ManyToMany
-- 37
  • 36 (a)
ManyToMany
-- 37
  • 35 (a)
ManyToMany
-- 37
  • 35 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta CG4046 38
  • 82 (a)
worm
(Caenorhabditis elegans)
Secernentea rps-16 38
  • 72 (a)
Species with no ortholog for ZNF90:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for ZNF90 Gene

ENSEMBL:
Gene Tree for ZNF90 (if available)
TreeFam:
Gene Tree for ZNF90 (if available)

Paralogs for ZNF90 Gene

Selected SIMAP similar genes for ZNF90 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF90: view

Variants for ZNF90 Gene

Sequence variations from dbSNP and Humsavar for ZNF90 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs765051 -- 20,098,780(-) AAAAA(C/T)CATTC intron-variant
rs836909 -- 20,095,378(+) aaggc(A/G)tttag intron-variant
rs836910 -- 20,096,821(+) AGCCC(A/C)CTGCC intron-variant
rs836911 -- 20,101,300(+) tagaa(C/T)tataa intron-variant
rs836912 -- 20,102,422(+) ttaga(C/T)tgtgg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF90 Gene

Variant ID Type Subtype PubMed ID
nsv519535 CNV Gain 19592680
esv2718296 CNV Deletion 23290073
dgv550e201 CNV Deletion 23290073
dgv3792n71 CNV Gain 21882294
esv2718298 CNV Deletion 23290073
esv2718300 CNV Deletion 23290073
nsv911320 CNV Gain 21882294
dgv630e199 CNV Deletion 23128226
nsv911321 CNV Gain 21882294
nsv911322 CNV Gain 21882294
dgv3793n71 CNV Gain 21882294
dgv3794n71 CNV Loss 21882294
dgv1061e1 CNV Complex 17122850
esv34357 CNV Gain 17911159
nsv817820 CNV Gain 17921354
nsv911327 CNV Loss 21882294
nsv911328 CNV Gain 21882294
essv24619 CNV CNV 17122850

Relevant External Links for ZNF90 Gene

HapMap Linkage Disequilibrium report
ZNF90

Disorders for ZNF90 Gene

No disorders were found for ZNF90 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF90 Gene

Publications for ZNF90 Gene

  1. The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins. (PMID: 2023909) Bellefroid E.J. … Martial J.A. (Proc. Natl. Acad. Sci. U.S.A. 1991) 3 4
  2. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PMID: 8467795) Bellefroid E.J. … Martial J.A. (EMBO J. 1993) 2 3
  3. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3 4
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for ZNF90 Gene

Sources for ZNF90 Gene

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