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Aliases for ZNF891 Gene

Aliases for ZNF891 Gene

  • Zinc Finger Protein 891 2 3
  • HCG1646157 3

External Ids for ZNF891 Gene

Previous GeneCards Identifiers for ZNF891 Gene

  • GC12M133698
  • GC12M130476

Summaries for ZNF891 Gene

GeneCards Summary for ZNF891 Gene

ZNF891 (Zinc Finger Protein 891) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF558.

UniProtKB/Swiss-Prot for ZNF891 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF891 Gene

Genomics for ZNF891 Gene

Genomic Location for ZNF891 Gene

133,106,817 bp from pter
133,130,473 bp from pter
23,657 bases
Minus strand

Genomic View for ZNF891 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for ZNF891 Gene

No data available for Regulatory Elements for ZNF891 Gene

Proteins for ZNF891 Gene

  • Protein details for ZNF891 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 891
    Protein Accession:

    Protein attributes for ZNF891 Gene

    544 amino acids
    Molecular mass:
    63592 Da
    Quaternary structure:
    No Data Available
    • Sequence=BC017932; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};

neXtProt entry for ZNF891 Gene

Proteomics data for ZNF891 Gene at MOPED

Post-translational modifications for ZNF891 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF891 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF891 Gene

Domains & Families for ZNF891 Gene

Gene Families for ZNF891 Gene

Protein Domains for ZNF891 Gene

Suggested Antigen Peptide Sequences for ZNF891 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 8 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 8 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF891: view

Function for ZNF891 Gene

Molecular function for ZNF891 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF891 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF891: view

Phenotypes for ZNF891 Gene

GenomeRNAi human phenotypes for ZNF891:
genes like me logo Genes that share phenotypes with ZNF891: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF891 Gene

Localization for ZNF891 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF891 Gene

Subcellular locations from

Jensen Localization Image for ZNF891 Gene COMPARTMENTS Subcellular localization image for ZNF891 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF891 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF891: view

Pathways & Interactions for ZNF891 Gene

SuperPathways for ZNF891 Gene

No Data Available

Interacting Proteins for ZNF891 Gene

Gene Ontology (GO) - Biological Process for ZNF891 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF891: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF891 Gene

Drugs & Compounds for ZNF891 Gene

No Compound Related Data Available

Transcripts for ZNF891 Gene

mRNA/cDNA for ZNF891 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF891 Gene

No ASD Table

Relevant External Links for ZNF891 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF891 Gene

mRNA expression in normal human tissues for ZNF891 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for ZNF891 Gene

genes like me logo Genes that share expression patterns with ZNF891: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF891 Gene

Orthologs for ZNF891 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF891 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC100125388 35
  • 82 (n)
  • 68 (a)
ZNF891 36
  • 40 (a)
(Pan troglodytes)
Mammalia LOC100610530 35
  • 99.51 (n)
  • 98.9 (a)
ZNF891 36
  • 99 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 31 (a)
-- 36
  • 40 (a)
-- 36
  • 33 (a)
-- 36
  • 33 (a)
-- 36
  • 41 (a)
-- 36
  • 47 (a)
(Mus musculus)
Mammalia 2410141K09Rik 36
  • 35 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 27 (a)
(Danio rerio)
Actinopterygii ZNF557 36
  • 21 (a)
Species with no ortholog for ZNF891:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF891 Gene

Gene Tree for ZNF891 (if available)
Gene Tree for ZNF891 (if available)

Paralogs for ZNF891 Gene

(461) SIMAP similar genes for ZNF891 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF891: view

Variants for ZNF891 Gene

Sequence variations from dbSNP and Humsavar for ZNF891 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs1011481 -- 133,125,140(-) TTTCC(A/G)TTTTC intron-variant
rs2062719 -- 133,126,029(-) TAGTA(C/T)AGTGT intron-variant
rs2173970 -- 133,120,544(+) ATAAA(A/C/G)ATTCT missense, reference
rs7133691 -- 133,126,608(+) aattc(C/T)aagac intron-variant
rs7138056 -- 133,127,684(+) gagat(C/T)taaca intron-variant

Variation tolerance for ZNF891 Gene

Gene Damage Index Score: 7.20; 80.95% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF891 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF891 Gene

Disorders for ZNF891 Gene

Relevant External Links for ZNF891

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ZNF891: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF891 Gene

Publications for ZNF891 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 67
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for ZNF891 Gene

Sources for ZNF891 Gene

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