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Aliases for ZNF888 Gene

Aliases for ZNF888 Gene

  • Zinc Finger Protein 888 2 3
  • CTD-2331H12.6 3

External Ids for ZNF888 Gene

Previous GeneCards Identifiers for ZNF888 Gene

  • GC19M053410

Summaries for ZNF888 Gene

GeneCards Summary for ZNF888 Gene

ZNF888 (Zinc Finger Protein 888) is a Protein Coding gene.

UniProtKB/Swiss-Prot for ZNF888 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF888 Gene

Genomics for ZNF888 Gene

Genomic Location for ZNF888 Gene

Start:
52,905,915 bp from pter
End:
52,923,470 bp from pter
Size:
17,556 bases
Orientation:
Minus strand

Genomic View for ZNF888 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF888 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF888 Gene

No data available for Regulatory Elements for ZNF888 Gene

Proteins for ZNF888 Gene

  • Protein details for ZNF888 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CJ79-ZN888_HUMAN
    Recommended name:
    Zinc finger protein 888
    Protein Accession:
    P0CJ79
    Secondary Accessions:

    Protein attributes for ZNF888 Gene

    Size:
    500 amino acids
    Molecular mass:
    58727 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF888 Gene

Proteomics data for ZNF888 Gene at MOPED

Post-translational modifications for ZNF888 Gene

  • Ubiquitination at Lys390
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ZNF888 Gene

Domains for ZNF888 Gene

Gene Families for ZNF888 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF888 Gene

Suggested Antigen Peptide Sequences for ZNF888 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0CJ79

UniProtKB/Swiss-Prot:

ZN888_HUMAN :
  • P0CJ79
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF888: view

Function for ZNF888 Gene

Molecular function for ZNF888 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF888 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF888: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF888 Gene

Localization for ZNF888 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF888 Gene

Gene Ontology (GO) - Cellular Components for ZNF888 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF888: view

No data available for Subcellular locations from COMPARTMENTS for ZNF888 Gene

Pathways for ZNF888 Gene

SuperPathways for ZNF888 Gene

No Data Available

Interacting Proteins for ZNF888 Gene

Gene Ontology (GO) - Biological Process for ZNF888 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF888: view

No data available for Pathways by source for ZNF888 Gene

Transcripts for ZNF888 Gene

mRNA/cDNA for ZNF888 Gene

(9) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF888 Gene

No ASD Table

Relevant External Links for ZNF888 Gene

GeneLoc Exon Structure for
ZNF888
ECgene alternative splicing isoforms for
ZNF888

Expression for ZNF888 Gene

mRNA expression in normal human tissues for ZNF888 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZNF888 Gene

This gene is overexpressed in Bladder (7.3).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ZNF888 Gene

genes like me logo Genes that share expressions with ZNF888: view

No data available for mRNA Expression by UniProt/SwissProt for ZNF888 Gene

Orthologs for ZNF888 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for ZNF888 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC456268 35
  • 95.44 (n)
  • 93.87 (a)
mouse
(Mus musculus)
Mammalia Gm13154 16
Species with no ortholog for ZNF888:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF888 Gene

ENSEMBL:
Gene Tree for ZNF888 (if available)
TreeFam:
Gene Tree for ZNF888 (if available)

Paralogs for ZNF888 Gene

Selected SIMAP similar genes for ZNF888 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF888: view

No data available for Paralogs for ZNF888 Gene

Variants for ZNF888 Gene

Sequence variations from dbSNP and Humsavar for ZNF888 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs723864 -- 52,917,105(+) TGAAT(A/C)TCCTG intron-variant
rs723865 -- 52,916,988(+) AGTAC(C/T)GCTCC intron-variant
rs1975043 -- 52,923,359(+) CAGAG(C/T)AAAAC intron-variant
rs1978615 -- 52,910,433(+) GCTAC(C/T)GCACT intron-variant
rs1978616 -- 52,910,572(+) tagcc(A/G)tgggt intron-variant

Relevant External Links for ZNF888 Gene

HapMap Linkage Disequilibrium report
ZNF888

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF888 Gene

Disorders for ZNF888 Gene

No disorders were found for ZNF888 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF888 Gene

Publications for ZNF888 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4

Products for ZNF888 Gene

Sources for ZNF888 Gene

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