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Aliases for ZNF880 Gene

Aliases for ZNF880 Gene

  • Zinc Finger Protein 880 2 3 5

External Ids for ZNF880 Gene

Previous GeneCards Identifiers for ZNF880 Gene

  • GC19P057568
  • GC19P052873
  • GC19P049203

Summaries for ZNF880 Gene

GeneCards Summary for ZNF880 Gene

ZNF880 (Zinc Finger Protein 880) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF528.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF880 Gene

Genomics for ZNF880 Gene

Regulatory Elements for ZNF880 Gene

Enhancers for ZNF880 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F052369 0.9 ENCODE 17.3 +0.3 276 1.5 HDAC1 TBP PKNOX1 ZBTB40 ETS1 ZNF280D SP3 ZNF518A ZFP69B SMARCA4 ZNF880 ZNF528-AS1 ENSG00000277977
GH19F052351 0.4 ENCODE 0.3 -18.2 -18195 0.2 CTCF ENSG00000269535 ZNF880
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF880 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF880 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001818714 284 1999 HDAC1 PKNOX1 ZBTB40 ETS1 ZNF280D SP3 ZNF518A ZFP69B SMARCA4 ZNF610

Genomic Location for ZNF880 Gene

Chromosome:
19
Start:
52,369,917 bp from pter
End:
52,385,795 bp from pter
Size:
15,879 bases
Orientation:
Plus strand

Genomic View for ZNF880 Gene

Genes around ZNF880 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF880 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF880 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF880 Gene

Proteins for ZNF880 Gene

  • Protein details for ZNF880 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PDB4-ZN880_HUMAN
    Recommended name:
    Zinc finger protein 880
    Protein Accession:
    Q6PDB4
    Secondary Accessions:
    • B4DNA6

    Protein attributes for ZNF880 Gene

    Size:
    577 amino acids
    Molecular mass:
    66762 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF880 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF880 Gene

Post-translational modifications for ZNF880 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF880 Gene

No data available for DME Specific Peptides for ZNF880 Gene

Domains & Families for ZNF880 Gene

Gene Families for ZNF880 Gene

Protein Domains for ZNF880 Gene

Suggested Antigen Peptide Sequences for ZNF880 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6PDB4

UniProtKB/Swiss-Prot:

ZN880_HUMAN :
  • Contains 1 KRAB domain.
  • Contains 14 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Similarity:
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF880: view

Function for ZNF880 Gene

Gene Ontology (GO) - Molecular Function for ZNF880 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF880: view

Phenotypes for ZNF880 Gene

genes like me logo Genes that share phenotypes with ZNF880: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF880 Gene

Localization for ZNF880 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF880 gene
Compartment Confidence
nucleus 3
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for ZNF880 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ZNF880: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZNF880 Gene

Pathways & Interactions for ZNF880 Gene

SuperPathways for ZNF880 Gene

No Data Available

Interacting Proteins for ZNF880 Gene

Gene Ontology (GO) - Biological Process for ZNF880 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF880: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF880 Gene

Transcripts for ZNF880 Gene

Unigene Clusters for ZNF880 Gene

Zinc finger protein 880:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF880 Gene

No ASD Table

Relevant External Links for ZNF880 Gene

GeneLoc Exon Structure for
ZNF880
ECgene alternative splicing isoforms for
ZNF880

Expression for ZNF880 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF880 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF880 Gene:

ZNF880

SOURCE GeneReport for Unigene cluster for ZNF880 Gene:

Hs.502314
genes like me logo Genes that share expression patterns with ZNF880: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF880 Gene

Orthologs for ZNF880 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF880 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF880 34
  • 90.24 (n)
-- 35
  • 79 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 48 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 31 (a)
ManyToMany
Species where no ortholog for ZNF880 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF880 Gene

ENSEMBL:
Gene Tree for ZNF880 (if available)
TreeFam:
Gene Tree for ZNF880 (if available)

Paralogs for ZNF880 Gene

(539) SIMAP similar genes for ZNF880 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZNF880 Gene

genes like me logo Genes that share paralogs with ZNF880: view

Variants for ZNF880 Gene

Sequence variations from dbSNP and Humsavar for ZNF880 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10409127 -- 52,389,322(+) agcaa(C/G)ttagt intron-variant
rs10415186 -- 52,388,546(+) actga(A/C/G)attac intron-variant
rs10415459 -- 52,388,113(+) gacct(C/T)gtgat intron-variant
rs10418649 -- 52,393,982(+) caggc(A/G)cccgc intron-variant, downstream-variant-500B
rs10419947 -- 52,393,836(+) ccccc(C/T)ttttt intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZNF880 Gene

Variant ID Type Subtype PubMed ID
nsv978839 CNV duplication 23825009
nsv956570 CNV deletion 24416366
nsv833873 CNV gain 17160897
nsv828615 CNV loss 20364138
nsv580011 CNV loss 21841781
nsv521079 CNV loss 19592680
nsv512590 CNV loss 21212237
nsv511613 CNV loss 21212237
nsv507900 OTHER sequence alteration 20534489
nsv476454 CNV novel sequence insertion 20440878
nsv2536 CNV deletion 18451855
nsv1140251 OTHER inversion 24896259
nsv1110930 OTHER inversion 24896259
nsv1109210 CNV deletion 24896259
esv3644692 CNV loss 21293372
esv3556562 CNV deletion 23714750
esv32843 CNV loss 17666407
esv28637 CNV loss 19812545
esv2750580 CNV loss 17666407
esv2718781 CNV deletion 23290073
dgv657e199 CNV deletion 23128226
dgv6525n54 CNV loss 21841781
dgv6524n54 CNV loss 21841781
dgv596n67 CNV loss 20364138
dgv1806n106 CNV deletion 24896259

Variation tolerance for ZNF880 Gene

Residual Variation Intolerance Score: 93.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.00; 92.06% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF880 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF880

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF880 Gene

Disorders for ZNF880 Gene

Relevant External Links for ZNF880

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF880

No disorders were found for ZNF880 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF880 Gene

Publications for ZNF880 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Gene expression profile of human bone marrow stromal cells: high-throughput expressed sequence tag sequencing analysis. (PMID: 11827452) Jia L. … Francomano C.A. (Genomics 2002) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ZNF880 Gene

Sources for ZNF880 Gene

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