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Aliases for ZNF879 Gene

Aliases for ZNF879 Gene

  • Zinc Finger Protein 879 2 3 5
  • DKFZp686E2433 3

External Ids for ZNF879 Gene

Previous GeneCards Identifiers for ZNF879 Gene

  • GC05P178384
  • GC05P178450
  • GC05P173177

Summaries for ZNF879 Gene

GeneCards Summary for ZNF879 Gene

ZNF879 (Zinc Finger Protein 879) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF354B.

UniProtKB/Swiss-Prot for ZNF879 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF879 Gene

Genomics for ZNF879 Gene

Regulatory Elements for ZNF879 Gene

Enhancers for ZNF879 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F178729 0.8 ENCODE 35.9 -293.3 -293298 1.8 ATF1 CREB3L1 ZFP64 ARID4B SIN3A ZNF2 ETS1 GLIS2 ZNF143 KLF7 ZNF354B ZNF354A ZNF879 ZNF454 LOC105377763 LOC100130798 ZFP2 ADAMTS2 HNRNPAB ENSG00000272431
GH05F179619 0.2 ENCODE 33.8 +598.6 598556 6.1 HDGF PKNOX1 CREB3L1 MLX WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZFP2 ZNF879 LOC100130798 LOC100996419 ZNF454 ZNF354C LOC100502572 LOC100289470 ENSG00000253652 ENSG00000250674
GH05F179677 0.6 ENCODE 33.8 +654.9 654875 2.3 HDGF PKNOX1 CREB3L1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 ZNF879 ZNF354B ZFP2 CNOT6 TBC1D9B MAML1 ZNF454 ZNF354C LOC100996419 LOC100130798
GH05F179696 0.6 ENCODE 33.3 +675.2 675213 4.9 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 MAML1 ZNF354B ZNF879 LOC105377763 ZNF454 CANX LOC100996419 MGAT4B LOC101928445 ZFP2
GH05F178203 0.2 ENCODE 28.6 -813.9 -813904 12.1 HDGF PKNOX1 CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZFP2 LOC100130798 ZNF454 ZNF879 ENSG00000247679 ZNF354C ZNF354B HNRNPAB LOC202181 CLK4
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZNF879 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF879 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001298157 69 2000 CREB3L1 ZNF2 ETS1 YY1 ZNF302 ZNF143 SP3 REST ZNF518A KAT8

Genomic Location for ZNF879 Gene

Chromosome:
5
Start:
179,023,732 bp from pter
End:
179,035,064 bp from pter
Size:
11,333 bases
Orientation:
Plus strand

Genomic View for ZNF879 Gene

Genes around ZNF879 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF879 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF879 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF879 Gene

Proteins for ZNF879 Gene

  • Protein details for ZNF879 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B4DU55-ZN879_HUMAN
    Recommended name:
    Zinc finger protein 879
    Protein Accession:
    B4DU55

    Protein attributes for ZNF879 Gene

    Size:
    563 amino acids
    Molecular mass:
    64577 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF879 Gene

Post-translational modifications for ZNF879 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF879 Gene

No data available for DME Specific Peptides for ZNF879 Gene

Domains & Families for ZNF879 Gene

Gene Families for ZNF879 Gene

Protein Domains for ZNF879 Gene

Suggested Antigen Peptide Sequences for ZNF879 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

B4DU55

UniProtKB/Swiss-Prot:

ZN879_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF879: view

Function for ZNF879 Gene

Molecular function for ZNF879 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF879 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF879: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF879 Gene

Localization for ZNF879 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF879 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF879 Gene COMPARTMENTS Subcellular localization image for ZNF879 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF879 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF879: view

Pathways & Interactions for ZNF879 Gene

SuperPathways for ZNF879 Gene

No Data Available

Interacting Proteins for ZNF879 Gene

Gene Ontology (GO) - Biological Process for ZNF879 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF879: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF879 Gene

Transcripts for ZNF879 Gene

mRNA/cDNA for ZNF879 Gene

(4) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF879 Gene

Zinc finger protein 879:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF879 Gene

No ASD Table

Relevant External Links for ZNF879 Gene

GeneLoc Exon Structure for
ZNF879
ECgene alternative splicing isoforms for
ZNF879

Expression for ZNF879 Gene

mRNA expression in normal human tissues for ZNF879 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF879 Gene:

ZNF879

SOURCE GeneReport for Unigene cluster for ZNF879 Gene:

Hs.445740
genes like me logo Genes that share expression patterns with ZNF879: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF879 Gene

Orthologs for ZNF879 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF879 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF879 34 35
  • 99.41 (n)
dog
(Canis familiaris)
Mammalia ZNF879 35
  • 90 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF879 34 35
  • 88.73 (n)
rat
(Rattus norvegicus)
Mammalia Zfp879 34
  • 80.18 (n)
mouse
(Mus musculus)
Mammalia Zfp879 34 16 35
  • 79.77 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 49 (a)
OneToMany
Species where no ortholog for ZNF879 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF879 Gene

ENSEMBL:
Gene Tree for ZNF879 (if available)
TreeFam:
Gene Tree for ZNF879 (if available)

Paralogs for ZNF879 Gene

Paralogs for ZNF879 Gene

(516) SIMAP similar genes for ZNF879 Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for ZNF879 Gene

genes like me logo Genes that share paralogs with ZNF879: view

Variants for ZNF879 Gene

Sequence variations from dbSNP and Humsavar for ZNF879 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs10464075 -- 179,028,197(+) GCTGC(A/G)CTCAA intron-variant
rs10479437 -- 179,026,041(+) GATTG(C/T)GCCAT intron-variant
rs10479519 -- 179,023,692(+) GGTTC(C/T)CTCTC upstream-variant-2KB
rs10479520 -- 179,024,446(+) TCTTG(A/C)GCCCT intron-variant, utr-variant-5-prime
rs10516149 -- 179,027,117(+) CTATA(G/T)CTCCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF879 Gene

Variant ID Type Subtype PubMed ID
dgv5845n100 CNV gain 25217958
nsv1027487 CNV gain 25217958
nsv1033597 CNV gain 25217958
nsv1120062 OTHER inversion 24896259

Variation tolerance for ZNF879 Gene

Gene Damage Index Score: 6.71; 78.65% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF879 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF879

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF879 Gene

Disorders for ZNF879 Gene

Relevant External Links for ZNF879

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF879

No disorders were found for ZNF879 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF879 Gene

Publications for ZNF879 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  2. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 4 64

Products for ZNF879 Gene

Sources for ZNF879 Gene

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