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Aliases for ZNF879 Gene

Aliases for ZNF879 Gene

  • Zinc Finger Protein 879 2 3 5
  • DKFZp686E2433 3

External Ids for ZNF879 Gene

Previous GeneCards Identifiers for ZNF879 Gene

  • GC05P178384
  • GC05P178450
  • GC05P173177

Summaries for ZNF879 Gene

GeneCards Summary for ZNF879 Gene

ZNF879 (Zinc Finger Protein 879) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF354B.

UniProtKB/Swiss-Prot for ZNF879 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF879 Gene

Genomics for ZNF879 Gene

Regulatory Elements for ZNF879 Gene

Enhancers for ZNF879 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G178203 1.4 ENCODE dbSUPER 29.9 -813.9 -813904 12.1 HDGF PKNOX1 ARNT CREB3L1 AGO1 WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ENSG00000254035 ZNF354C ZFP2 ZNF879 ZNF454 ENSG00000247679 CLK4 ENSG00000272431 LOC202181 RMND5B
GH05G178729 1.1 ENCODE 33.8 -293.3 -293298 1.8 CREB3L1 ZFP64 ARID4B SIN3A ZNF2 YY1 ZNF766 ZNF143 KLF13 SP3 ZNF354A ZNF354B ENSG00000254035 ZNF879 ZNF454 LOC105377763 ZFP2 ENSG00000272431 HMGB3P22 PIR45014
GH05G179793 1 ENCODE 24.6 +771.6 771571 4.5 HDGF AGO1 ARID4B SIN3A GLI4 ZNF2 ZNF48 ZNF121 GLIS2 ELK1 ZNF879 ZFP2 ENSG00000254035 LOC100996419 ENSG00000248367 ZNF354C ZNF454 MGAT4B MRNIP MAML1
GH05G179758 1.5 Ensembl ENCODE dbSUPER 15.4 +736.1 736069 2.0 HDGF PKNOX1 MLX ARID4B DMAP1 ZNF48 ZNF121 FOS ZNF263 SP5 MAML1 CANX ZNF879 LTC4S MIR1229 MGAT4B SQSTM1 HMGB3P22 CBY3 ZNF354B
GH05G179549 1.1 ENCODE 19.2 +526.8 526772 2.8 ARNT SIN3A ZNF2 YY1 ZNF766 ZNF263 ZHX2 MXD4 ZNF592 KAT8 ZNF354B RUFY1 ZNF879 ZNF354C MAML1 LOC105377763 LOC105377762 GC05P179544
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF879 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF879 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000191499 69 1600 ATF1 CREB3L1 SIN3A ZNF2 YY1 ETS1 ELK1 ZNF302 ZNF143 SP3

Genomic Location for ZNF879 Gene

Chromosome:
5
Start:
179,023,732 bp from pter
End:
179,035,064 bp from pter
Size:
11,333 bases
Orientation:
Plus strand

Genomic View for ZNF879 Gene

Genes around ZNF879 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF879 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF879 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF879 Gene

Proteins for ZNF879 Gene

  • Protein details for ZNF879 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B4DU55-ZN879_HUMAN
    Recommended name:
    Zinc finger protein 879
    Protein Accession:
    B4DU55

    Protein attributes for ZNF879 Gene

    Size:
    563 amino acids
    Molecular mass:
    64577 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF879 Gene

Post-translational modifications for ZNF879 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF879 Gene

No data available for DME Specific Peptides for ZNF879 Gene

Domains & Families for ZNF879 Gene

Gene Families for ZNF879 Gene

Protein Domains for ZNF879 Gene

Suggested Antigen Peptide Sequences for ZNF879 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

B4DU55

UniProtKB/Swiss-Prot:

ZN879_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF879: view

Function for ZNF879 Gene

Molecular function for ZNF879 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF879 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF879: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF879 Gene

Localization for ZNF879 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF879 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF879 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF879 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF879: view

Pathways & Interactions for ZNF879 Gene

SuperPathways for ZNF879 Gene

No Data Available

Interacting Proteins for ZNF879 Gene

Gene Ontology (GO) - Biological Process for ZNF879 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF879: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF879 Gene

Drugs & Compounds for ZNF879 Gene

No Compound Related Data Available

Transcripts for ZNF879 Gene

mRNA/cDNA for ZNF879 Gene

Unigene Clusters for ZNF879 Gene

Zinc finger protein 879:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF879 Gene

No ASD Table

Relevant External Links for ZNF879 Gene

GeneLoc Exon Structure for
ZNF879
ECgene alternative splicing isoforms for
ZNF879

Expression for ZNF879 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF879 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF879 Gene:

ZNF879

SOURCE GeneReport for Unigene cluster for ZNF879 Gene:

Hs.445740
genes like me logo Genes that share expression patterns with ZNF879: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF879 Gene

Orthologs for ZNF879 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF879 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF879 34 35
  • 99.41 (n)
dog
(Canis familiaris)
Mammalia ZNF879 35
  • 90 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF879 34 35
  • 88.73 (n)
rat
(Rattus norvegicus)
Mammalia Zfp879 34
  • 80.18 (n)
mouse
(Mus musculus)
Mammalia Zfp879 34 16 35
  • 79.77 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 49 (a)
OneToMany
Species where no ortholog for ZNF879 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF879 Gene

ENSEMBL:
Gene Tree for ZNF879 (if available)
TreeFam:
Gene Tree for ZNF879 (if available)

Paralogs for ZNF879 Gene

(516) SIMAP similar genes for ZNF879 Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for ZNF879 Gene

genes like me logo Genes that share paralogs with ZNF879: view

Variants for ZNF879 Gene

Sequence variations from dbSNP and Humsavar for ZNF879 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1000106398 -- 179,034,687(+) AGCAA(A/G)TGGAC downstream-variant-500B
rs1000264654 -- 179,023,172(+) AGTGC(A/G)ATGGC upstream-variant-2KB
rs1000716792 -- 179,024,722(+) GGCAG(A/G)TGGTC intron-variant, utr-variant-5-prime
rs1000850498 -- 179,033,774(+) CACAT(C/T)AGAGA utr-variant-3-prime
rs1001345262 -- 179,034,006(+) ATCTA(A/G)GAATC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF879 Gene

Variant ID Type Subtype PubMed ID
dgv5845n100 CNV gain 25217958
nsv1027487 CNV gain 25217958
nsv1033597 CNV gain 25217958
nsv1120062 OTHER inversion 24896259

Variation tolerance for ZNF879 Gene

Gene Damage Index Score: 6.71; 78.65% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF879 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF879

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF879 Gene

Disorders for ZNF879 Gene

Relevant External Links for ZNF879

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF879

No disorders were found for ZNF879 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF879 Gene

Publications for ZNF879 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  2. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 4 64

Products for ZNF879 Gene

Sources for ZNF879 Gene

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