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Aliases for ZNF878 Gene

Aliases for ZNF878 Gene

  • Zinc Finger Protein 878 2 3

External Ids for ZNF878 Gene

Summaries for ZNF878 Gene

GeneCards Summary for ZNF878 Gene

ZNF878 (Zinc Finger Protein 878) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF709.

UniProtKB/Swiss-Prot for ZNF878 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF878 Gene

Genomics for ZNF878 Gene

Genomic Location for ZNF878 Gene

Start:
12,043,805 bp from pter
End:
12,052,967 bp from pter
Size:
9,163 bases
Orientation:
Minus strand

Genomic View for ZNF878 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF878 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF878 Gene

No data available for Regulatory Elements for ZNF878 Gene

Proteins for ZNF878 Gene

  • Protein details for ZNF878 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9JN71-ZN878_HUMAN
    Recommended name:
    Zinc finger protein 878
    Protein Accession:
    C9JN71
    Secondary Accessions:

    Protein attributes for ZNF878 Gene

    Size:
    531 amino acids
    Molecular mass:
    61540 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF878 Gene

Proteomics data for ZNF878 Gene at MOPED

Post-translational modifications for ZNF878 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF878 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF878 Gene

Domains for ZNF878 Gene

Gene Families for ZNF878 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF878 Gene

UniProtKB/Swiss-Prot:

ZN878_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • C9JN71
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • C9JN71
Similarity:
  • Contains 15 C2H2-type zinc fingers.:
    • C9JN71
genes like me logo Genes that share domains with ZNF878: view

Function for ZNF878 Gene

Molecular function for ZNF878 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF878 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF878: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF878 Gene

Localization for ZNF878 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF878 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF878 Gene COMPARTMENTS Subcellular localization image for ZNF878 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF878 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF878: view

Pathways for ZNF878 Gene

SuperPathways for ZNF878 Gene

No Data Available

Interacting Proteins for ZNF878 Gene

Gene Ontology (GO) - Biological Process for ZNF878 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF878: view

No data available for Pathways by source for ZNF878 Gene

Transcripts for ZNF878 Gene

mRNA/cDNA for ZNF878 Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF878 Gene

Zinc finger protein 878:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF878 Gene

No ASD Table

Relevant External Links for ZNF878 Gene

GeneLoc Exon Structure for
ZNF878
ECgene alternative splicing isoforms for
ZNF878

Expression for ZNF878 Gene

mRNA expression in normal human tissues for ZNF878 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF878 Gene

SOURCE GeneReport for Unigene cluster for ZNF878 Gene Hs.704229

genes like me logo Genes that share expressions with ZNF878: view

Orthologs for ZNF878 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF878 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF878 36
  • 99.4 (n)
  • 98.61 (a)
ZNF878 37
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm14408 37
  • 50 (a)
ManyToMany
Zfp617 36
  • 68.25 (n)
  • 55.7 (a)
Zfp958 16
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 45 (a)
ManyToMany
-- 37
  • 53 (a)
ManyToMany
-- 37
  • 46 (a)
ManyToMany
-- 37
  • 46 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 45 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia LOC102548917 36
  • 66.98 (n)
  • 54.08 (a)
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 40 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii CR388132.2 37
  • 40 (a)
ManyToMany
CT573234.2 37
  • 41 (a)
ManyToMany
Species with no ortholog for ZNF878:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF878 Gene

ENSEMBL:
Gene Tree for ZNF878 (if available)
TreeFam:
Gene Tree for ZNF878 (if available)

Paralogs for ZNF878 Gene

Selected SIMAP similar genes for ZNF878 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF878: view

Variants for ZNF878 Gene

Sequence variations from dbSNP and Humsavar for ZNF878 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs7246419 -- 12,051,897(+) AGCGA(A/G)ACTCC intron-variant
rs7248287 -- 12,054,614(+) GGTTG(C/T)AGTGA upstream-variant-2KB
rs7248680 -- 12,054,955(+) AAGAG(C/T)CTATC upstream-variant-2KB
rs7255420 -- 12,047,024(+) AAGTC(A/G)TGCTG intron-variant
rs7257355 -- 12,050,965(+) GTGGC(A/G)GGCGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF878 Gene

Variant ID Type Subtype PubMed ID
nsv525966 CNV Gain 19592680
nsv911068 CNV Gain 21882294
nsv911069 CNV Loss 21882294

Relevant External Links for ZNF878 Gene

HapMap Linkage Disequilibrium report
ZNF878

Disorders for ZNF878 Gene

No disorders were found for ZNF878 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF878 Gene

Publications for ZNF878 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  2. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for ZNF878 Gene

Sources for ZNF878 Gene

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