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Aliases for ZNF878 Gene

Aliases for ZNF878 Gene

  • Zinc Finger Protein 878 2 3 5

External Ids for ZNF878 Gene

Previous GeneCards Identifiers for ZNF878 Gene

  • GC19M012017
  • GC19M012154
  • GC19M011728

Summaries for ZNF878 Gene

GeneCards Summary for ZNF878 Gene

ZNF878 (Zinc Finger Protein 878) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ENSG00000196826.

UniProtKB/Swiss-Prot for ZNF878 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF878 Gene

Genomics for ZNF878 Gene

Regulatory Elements for ZNF878 Gene

Enhancers for ZNF878 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF878 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF878 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF878 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF878 Gene

12,043,648 bp from pter
12,052,967 bp from pter
9,320 bases
Minus strand

Genomic View for ZNF878 Gene

Genes around ZNF878 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF878 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF878 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF878 Gene

Proteins for ZNF878 Gene

  • Protein details for ZNF878 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 878
    Protein Accession:

    Protein attributes for ZNF878 Gene

    531 amino acids
    Molecular mass:
    61540 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF878 Gene

Proteomics data for ZNF878 Gene at MOPED

Post-translational modifications for ZNF878 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF878 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF878 Gene

Domains & Families for ZNF878 Gene

Gene Families for ZNF878 Gene

Protein Domains for ZNF878 Gene

Suggested Antigen Peptide Sequences for ZNF878 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 15 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 15 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF878: view

Function for ZNF878 Gene

Molecular function for ZNF878 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF878 Gene

GenomeRNAi human phenotypes for ZNF878:
genes like me logo Genes that share phenotypes with ZNF878: view

Animal Model Products

CRISPR Products

miRNA for ZNF878 Gene

miRTarBase miRNAs that target ZNF878

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF878 Gene

Localization for ZNF878 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF878 Gene

Subcellular locations from

Jensen Localization Image for ZNF878 Gene COMPARTMENTS Subcellular localization image for ZNF878 gene
Compartment Confidence
nucleus 3

No data available for Gene Ontology (GO) - Cellular Components for ZNF878 Gene

Pathways & Interactions for ZNF878 Gene

SuperPathways for ZNF878 Gene

No Data Available

Interacting Proteins for ZNF878 Gene

Gene Ontology (GO) - Biological Process for ZNF878 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZNF878 Gene

Drugs & Compounds for ZNF878 Gene

No Compound Related Data Available

Transcripts for ZNF878 Gene

mRNA/cDNA for ZNF878 Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF878 Gene

Zinc finger protein 878:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF878 Gene

No ASD Table

Relevant External Links for ZNF878 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF878 Gene

mRNA expression in normal human tissues for ZNF878 Gene

Protein differential expression in normal tissues from HIPED for ZNF878 Gene

This gene is overexpressed in Bone marrow stromal cell (61.6) and Bone marrow mesenchymal stem cell (7.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF878 Gene

SOURCE GeneReport for Unigene cluster for ZNF878 Gene Hs.704229

genes like me logo Genes that share expression patterns with ZNF878: view

Protein tissue co-expression partners for ZNF878 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF878 Gene

Orthologs for ZNF878 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF878 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Zfp617 35
  • 68.25 (n)
  • 55.7 (a)
Zfp617 16
Gm14408 36
  • 50 (a)
(Pan troglodytes)
Mammalia ZNF878 35
  • 99.4 (n)
  • 98.61 (a)
ZNF878 36
  • 90 (a)
(Rattus norvegicus)
Mammalia LOC102548917 35
  • 66.98 (n)
  • 54.08 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 45 (a)
-- 36
  • 53 (a)
-- 36
  • 46 (a)
-- 36
  • 46 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 45 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 40 (a)
(Danio rerio)
Actinopterygii CR388132.2 36
  • 40 (a)
CT573234.2 36
  • 41 (a)
Species with no ortholog for ZNF878:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF878 Gene

Gene Tree for ZNF878 (if available)
Gene Tree for ZNF878 (if available)

Paralogs for ZNF878 Gene

(530) SIMAP similar genes for ZNF878 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF878: view

Variants for ZNF878 Gene

Sequence variations from dbSNP and Humsavar for ZNF878 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7257355 -- 12,050,965(+) GTGGC(A/G)GGCGC intron-variant
rs8100428 -- 12,050,430(+) ATCTC(C/T)GATTA intron-variant
rs12982949 -- 12,051,118(+) aaaaa(A/G)gaaaa intron-variant
rs12984967 -- 12,054,173(+) ggtgg(C/T)gggcg upstream-variant-2KB
rs8106275 -- 12,049,448(+) agagc(A/G)agact intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF878 Gene

Variant ID Type Subtype PubMed ID
nsv525966 CNV Gain 19592680
nsv911068 CNV Gain 21882294
nsv911069 CNV Loss 21882294

Variation tolerance for ZNF878 Gene

Residual Variation Intolerance Score: 92% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.97; 68.16% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF878 Gene

Disorders for ZNF878 Gene

Relevant External Links for ZNF878

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF878 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF878 Gene

Publications for ZNF878 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 67

Products for ZNF878 Gene

Sources for ZNF878 Gene