Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF865 Gene

Aliases for ZNF865 Gene

  • Zinc Finger Protein 865 2 3 5

External Ids for ZNF865 Gene

Previous GeneCards Identifiers for ZNF865 Gene

  • GC19P056125

Summaries for ZNF865 Gene

GeneCards Summary for ZNF865 Gene

ZNF865 (Zinc Finger Protein 865) is a Protein Coding gene. GO annotations related to this gene include transcription cofactor activity.

UniProtKB/Swiss-Prot for ZNF865 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF865 Gene

Genomics for ZNF865 Gene

Regulatory Elements for ZNF865 Gene

Enhancers for ZNF865 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F055633 1.4 FANTOM5 ENCODE 12.9 +30.1 30129 3.2 HDGF PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 ZNF784 ZNF865 ZNF581 ZNF583 ZNF471 ZNF628 ZFP28 ZNF580 CCDC106
GH19F055544 1.4 FANTOM5 ENCODE 12.8 -57.4 -57424 6.2 ARID4B ZNF48 ZNF143 FOS SP5 JUNB NCOA1 PPARG SMARCB1 KAT8 ZNF784 ZNF865 ZNF581 ZNF628 SBK3 SBK2 LOC646709 KIR2DS4 ZNF471 SSC5D
GH19F055215 1.2 ENCODE 12.6 -388.7 -388701 2.9 CREB3L1 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF548 ZNF263 U2AF2 LENG8-AS1 ENSG00000235681 ENSG00000267523 ZNF581 ZNF628 ZNF580 ENSG00000267096 KMT5C RFPL4AP1
GH19F055397 1.1 FANTOM5 Ensembl 12.7 -204.6 -204647 5.9 CTCF KLF1 BCL11B RAD21 ZEB1 ZNF7 ZNF121 ZNF335 ZNF664 GATA3 ZNF784 ZNF865 BRSK1 TMEM86B ZNF581 ZNF628 TMEM150B RPL28 UBE2S PPP1R12C
GH19F055111 1.5 FANTOM5 ENCODE 5.9 -490.0 -490023 8.0 HDGF PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A YBX1 FEZF1 DMAP1 ZNF2 EPS8L1 RDH13 U2AF2 LENG8-AS1 CDC42EP5 ENSG00000235681 ENSG00000267523 ZNF580 KMT5C TNNT1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF865 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF865 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000045538 95 2201 HDGF ARNT SIN3A DMAP1 ZNF2 YY1 ZNF143 KLF13 SP3 JUNB

Genomic Location for ZNF865 Gene

Chromosome:
19
Start:
55,605,405 bp from pter
End:
55,618,545 bp from pter
Size:
13,141 bases
Orientation:
Plus strand

Genomic View for ZNF865 Gene

Genes around ZNF865 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF865 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF865 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF865 Gene

Proteins for ZNF865 Gene

  • Protein details for ZNF865 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CJ78-ZN865_HUMAN
    Recommended name:
    Zinc finger protein 865
    Protein Accession:
    P0CJ78

    Protein attributes for ZNF865 Gene

    Size:
    1059 amino acids
    Molecular mass:
    111077 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF865 Gene

Post-translational modifications for ZNF865 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF865 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF865 Gene

Domains & Families for ZNF865 Gene

Gene Families for ZNF865 Gene

Protein Domains for ZNF865 Gene

Suggested Antigen Peptide Sequences for ZNF865 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0CJ78

UniProtKB/Swiss-Prot:

ZN865_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 20 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 20 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF865: view

Function for ZNF865 Gene

Molecular function for ZNF865 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF865 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003712 transcription cofactor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF865: view

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF865 Gene

Localization for ZNF865 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF865 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF865 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF865 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF865: view

Pathways & Interactions for ZNF865 Gene

SuperPathways for ZNF865 Gene

No Data Available

Interacting Proteins for ZNF865 Gene

Gene Ontology (GO) - Biological Process for ZNF865 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription from RNA polymerase II promoter IBA --
genes like me logo Genes that share ontologies with ZNF865: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF865 Gene

Transcripts for ZNF865 Gene

mRNA/cDNA for ZNF865 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF865 Gene

Zinc finger protein 865:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF865 Gene

No ASD Table

Relevant External Links for ZNF865 Gene

GeneLoc Exon Structure for
ZNF865
ECgene alternative splicing isoforms for
ZNF865

Expression for ZNF865 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF865 Gene

Protein differential expression in normal tissues from HIPED for ZNF865 Gene

This gene is overexpressed in Blymphocyte (28.2), CD4 Tcells (24.9), and Retina (15.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF865 Gene



Protein tissue co-expression partners for ZNF865 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF865 Gene:

ZNF865

SOURCE GeneReport for Unigene cluster for ZNF865 Gene:

Hs.729114
genes like me logo Genes that share expression patterns with ZNF865: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF865 Gene

Orthologs for ZNF865 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF865 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF865 34
  • 99.01 (n)
dog
(Canis familiaris)
Mammalia ZNF865 34 35
  • 86.95 (n)
mouse
(Mus musculus)
Mammalia Zfp865 34 16 35
  • 83.6 (n)
rat
(Rattus norvegicus)
Mammalia LOC100911196 34
  • 83.41 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia znf865 34
  • 64.69 (n)
zebrafish
(Danio rerio)
Actinopterygii znf865 35
  • 17 (a)
OneToOne
Species where no ortholog for ZNF865 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF865 Gene

ENSEMBL:
Gene Tree for ZNF865 (if available)
TreeFam:
Gene Tree for ZNF865 (if available)

Paralogs for ZNF865 Gene

genes like me logo Genes that share paralogs with ZNF865: view

No data available for Paralogs for ZNF865 Gene

Variants for ZNF865 Gene

Sequence variations from dbSNP and Humsavar for ZNF865 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs111566976 -- 55,617,708(+) CATGA(C/T)ACAGC utr-variant-3-prime
rs112227172 -- 55,618,174(+) CCTGG(A/G)TGACA utr-variant-3-prime
rs112693887 -- 55,618,027(+) ACCCC(A/G)TCTCT utr-variant-3-prime
rs113750741 -- 55,618,400(+) TGGGC(A/G)TGATG utr-variant-3-prime
rs114008392 -- 55,611,879(+) GTTAC(A/G)GGTGC nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF865 Gene

Variant ID Type Subtype PubMed ID
nsv953624 CNV deletion 24416366
nsv828643 CNV loss 20364138
esv2658464 CNV deletion 23128226

Variation tolerance for ZNF865 Gene

Gene Damage Index Score: 1.48; 28.92% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF865 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF865

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF865 Gene

Disorders for ZNF865 Gene

Relevant External Links for ZNF865

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF865

No disorders were found for ZNF865 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF865 Gene

Publications for ZNF865 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4 64
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  3. The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis. (PMID: 26687479) Oliviero G. … Cagney G. (Sci. Rep. 2015) 3 64

Products for ZNF865 Gene

Sources for ZNF865 Gene

Content
Loading form....