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Aliases for ZNF865 Gene

Aliases for ZNF865 Gene

  • Zinc Finger Protein 865 2 3 5

External Ids for ZNF865 Gene

Previous GeneCards Identifiers for ZNF865 Gene

  • GC19P056125

Summaries for ZNF865 Gene

GeneCards Summary for ZNF865 Gene

ZNF865 (Zinc Finger Protein 865) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transcription cofactor activity.

UniProtKB/Swiss-Prot for ZNF865 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF865 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF865 Gene

Genomics for ZNF865 Gene

GeneHancer (GH) Regulatory Elements for ZNF865 Gene

Promoters and enhancers for ZNF865 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I055603 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.8 -0.1 -120 3.9 HDGF ARNT SIN3A DMAP1 ZNF2 ZBTB7B YY1 POLR2B E2F8 ZNF143 ZNF865 ZNF580 ZNF582 ZNF471 FIZ1 ZNF542P ZFP28 ZNF470 SSC5D NAT14
GH19I055111 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 5.9 -490.0 -490022 8 HDGF ARNT ARID4B SIN3A YBX1 FEZF1 DMAP1 ZNF2 YY1 POLR2B PPP1R12C GC19M055111 EPS8L1 RDH13 U2AF2 LENG8-AS1 LENG8 ENSG00000235681 CNOT3 ENSG00000267523
GH19I056104 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 2.8 +504.6 504586 10.7 HDGF FOXA2 PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 ZNF48 GLIS2 ZNF865 EPN1 ENSG00000223060 ZNF787 GC19M056096 GC19P056014
GH19I055337 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 1.6 -265.6 -265577 4 CLOCK MLX FEZF1 DMAP1 YY1 E2F8 ZNF143 ZNF548 SP3 NFYC KMT5C ENSG00000276831 LENG8-AS1 U2AF2 LENG8 ZNF628 ENSG00000235681 ENSG00000267523 ENSG00000267096 FAM71E2
GH19I055607 Enhancer 0.3 FANTOM5 0.8 +2.2 2197 0.3 SSC5D NAT14 TNNT1 COX6B2 ZNF865 ENSG00000276488
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF865 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF865 Gene

Genomic Locations for ZNF865 Gene
chr19:55,605,405-55,618,545
(GRCh38/hg38)
Size:
13,141 bases
Orientation:
Plus strand
chr19:56,116,771-56,129,911
(GRCh37/hg19)

Genomic View for ZNF865 Gene

Genes around ZNF865 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF865 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF865 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF865 Gene

Proteins for ZNF865 Gene

  • Protein details for ZNF865 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CJ78-ZN865_HUMAN
    Recommended name:
    Zinc finger protein 865
    Protein Accession:
    P0CJ78

    Protein attributes for ZNF865 Gene

    Size:
    1059 amino acids
    Molecular mass:
    111077 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF865 Gene

Post-translational modifications for ZNF865 Gene

No Post-translational modifications

Other Protein References for ZNF865 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF865 Gene

Domains & Families for ZNF865 Gene

Gene Families for ZNF865 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF865 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF865 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0CJ78

UniProtKB/Swiss-Prot:

ZN865_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF865: view

Function for ZNF865 Gene

Molecular function for ZNF865 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF865 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF865: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF865 Gene

Localization for ZNF865 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF865 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF865 gene
Compartment Confidence
nucleus 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoli (2)
  • Nucleus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF865 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF865: view

Pathways & Interactions for ZNF865 Gene

SuperPathways for ZNF865 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF865 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF865: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF865 Gene

Drugs & Compounds for ZNF865 Gene

No Compound Related Data Available

Transcripts for ZNF865 Gene

mRNA/cDNA for ZNF865 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF865 Gene

Zinc finger protein 865:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF865 Gene

No ASD Table

Relevant External Links for ZNF865 Gene

GeneLoc Exon Structure for
ZNF865
ECgene alternative splicing isoforms for
ZNF865

Expression for ZNF865 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF865 Gene

Protein differential expression in normal tissues from HIPED for ZNF865 Gene

This gene is overexpressed in Blymphocyte (28.2), CD4 Tcells (24.9), and Retina (15.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF865 Gene



Protein tissue co-expression partners for ZNF865 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF865 Gene:

ZNF865

SOURCE GeneReport for Unigene cluster for ZNF865 Gene:

Hs.729114
genes like me logo Genes that share expression patterns with ZNF865: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF865 Gene

Orthologs for ZNF865 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF865 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF865 33
  • 99.01 (n)
dog
(Canis familiaris)
Mammalia ZNF865 33 34
  • 86.95 (n)
mouse
(Mus musculus)
Mammalia Zfp865 33 16 34
  • 83.6 (n)
rat
(Rattus norvegicus)
Mammalia LOC100911196 33
  • 83.41 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia znf865 33
  • 64.69 (n)
zebrafish
(Danio rerio)
Actinopterygii znf865 34
  • 17 (a)
OneToOne
Species where no ortholog for ZNF865 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF865 Gene

ENSEMBL:
Gene Tree for ZNF865 (if available)
TreeFam:
Gene Tree for ZNF865 (if available)

Paralogs for ZNF865 Gene

genes like me logo Genes that share paralogs with ZNF865: view

No data available for Paralogs for ZNF865 Gene

Variants for ZNF865 Gene

Sequence variations from dbSNP and Humsavar for ZNF865 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000067108 -- 55,615,857(+) A/G coding_sequence_variant, missense_variant
rs1000418745 -- 55,616,132(+) C/T coding_sequence_variant, synonymous_variant
rs1001473141 -- 55,613,031(+) G/A upstream_transcript_variant
rs1002203449 -- 55,614,300(+) G/A coding_sequence_variant, missense_variant
rs1002535594 -- 55,618,028(+) T/C 3_prime_UTR_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF865 Gene

Variant ID Type Subtype PubMed ID
esv2658464 CNV deletion 23128226
nsv828643 CNV loss 20364138
nsv953624 CNV deletion 24416366

Variation tolerance for ZNF865 Gene

Gene Damage Index Score: 1.48; 28.92% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF865 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF865

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF865 Gene

Disorders for ZNF865 Gene

Additional Disease Information for ZNF865

No disorders were found for ZNF865 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF865 Gene

Publications for ZNF865 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4 58
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  3. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  5. The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis. (PMID: 26687479) Oliviero G … Cagney G (Scientific reports 2015) 3 58

Products for ZNF865 Gene

Sources for ZNF865 Gene

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