ZNF862 Gene
protein-coding GIFtS: 43
GCID: GC07P149535
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zinc finger protein 862
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Aliases
for ZNF862 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 8621 2 | | KIAA05433 |
Export aliases for ZNF862 gene to outside databasesPrevious GC identifers: GC07P149166 GC07P143610 |
Summaries
for ZNF862 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN862_HUMAN, O60290Function: May be involved in transcriptional regulation (By similarity)
|
Genomic Views
for ZNF862 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007914.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF862 gene promoter:
NF-1/L NF-1 Lmo2 AP-2gamma E47 HEN1 AP-2beta Hand1 AP-2alpha AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF862
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF862 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q36.1 Ensembl cytogenetic band: 7q36.1 HGNC cytogenetic band: 7q36.1ZNF862 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P149535: view genomic region
(about GC identifiers)
Start:
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149,535,456 bp from pter |
End:
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149,564,568 bp from pter |
Size:
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29,113 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 148,873,528-148,902,587 |
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Proteins
for ZNF862 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN862_HUMAN, O60290 (See
protein sequence)Recommended Name: Zinc finger protein 862 Size: 1169 amino acids; 131654 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: A0AUL8Alternative splicing: 2 isoforms: O60290-1 O60290-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZNF862: NX_O60290
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O60290
ZNF862 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001092690.1
ENSEMBL proteins: ENSP00000223210 ENSP00000417450
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF862 for ontologies About GeneDecksing
ZNF862 Antibody Products:
Assay Products for ZNF862: |
Protein
Domains /
Families
for ZNF862 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF862 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O60290ProtoNet protein and cluster: O60290 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN862_HUMAN, O60290Similarity: Contains 2 KRAB domainsSimilarity: Contains 2 TTF-type zinc fingers |
Function
for ZNF862 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN862_HUMAN, O60290Function: May be involved in transcriptional regulation (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF862
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF862
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for ZNF862 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF862 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF862 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
ZNF862 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF862 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF862
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
5/7 Interacting proteins for ZNF862 (O602902, 3 ENSP000002232104) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | | GO:0008150 | biological_process |
ND | -- |
ZNF862 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF862 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF862
Search CenterWatch for drugs/clinical trials and news about ZNF862 / ZN862
|
Transcripts
for ZNF862 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF862 gene: NM_001099220.1 Unigene Cluster for ZNF862: Zinc finger protein 862 Hs.731923 [show with all ESTs]Unigene Representative Sequence: NM_0010992206 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000223210(uc010lpn.3) ENST00000489820 ENST00000460379 ENST00000488265
ENST00000466435 ENST00000478024
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF862
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF862
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF862 (NM_001099220) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF862 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF862 |
Additional cDNA sequence: AK054924.1 AK128787.1 BC041427.1 BC045757.1 BC092506.1 BC113087.1 11 DOTS entries: DT.99950625 DT.211597 DT.411971 DT.100813852 DT.75105802 DT.100813851 DT.91838669 DT.121117194 DT.121117228 DT.100742684 DT.95157722
GeneLoc Exon Structure
|
Expression
for ZNF862 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF862 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTGATTCCT
About this image
See ZNF862 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF862
SOURCE GeneReport for Unigene cluster: Hs.731923
SABiosciences Custom PCR Arrays for ZNF862
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF862
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF862 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF862 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF862 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF862 |
Orthologs
for ZNF862 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF862 (if available)
TreeFam Gene Tree for ZNF862 (if available) |
Paralogs
for ZNF862 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF862 gene
- KIAA15862
1 SIMAP similar gene for ZNF862 using alignment to 2 protein entries: ZN862_HUMAN (see all proteins):ZNF250
ZNF862 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ZNF862
PGOHUM00000242659 PGOHUM00000236284
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Genomic Variants
for ZNF862 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF862 (149535456 - 149564568 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for ZNF862
6 CNVs: 31399 2716 3709 52146 53781 52150 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF862 |
|
Disorders
/ Diseases
for ZNF862 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF862 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF862 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF862) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2 Nagase T....Ohara O. (1998)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF862 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF862 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF862 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZNF862 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF862 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF862 gene:
Search GeneIP for patents involving ZNF862
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF862 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF862 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF862 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF862 | | | OriGene Protein Over-expression Lysate for ZNF862 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF862 | | OriGene 3'-UTR Clone for ZNF862 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF862 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF862 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF862 | | OriGene Custom Protein Services for ZNF862 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF862 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF862 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF862 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF862 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF862 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF862 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZNF862 |
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 | | | ZNF862 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF862 |
|  |  |  | | | | ThermoFisher Antibodies for ZNF862 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF862 |
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