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Aliases for ZNF862 Gene

Aliases for ZNF862 Gene

  • Zinc Finger Protein 862 2 3 5
  • KIAA0543 4

External Ids for ZNF862 Gene

Previous GeneCards Identifiers for ZNF862 Gene

  • GC07P149166
  • GC07P149535
  • GC07P143610

Summaries for ZNF862 Gene

GeneCards Summary for ZNF862 Gene

ZNF862 (Zinc Finger Protein 862) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and protein dimerization activity. An important paralog of this gene is PRDM11.

UniProtKB/Swiss-Prot for ZNF862 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF862 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF862 Gene

Genomics for ZNF862 Gene

Regulatory Elements for ZNF862 Gene

Enhancers for ZNF862 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H150364 1.8 FANTOM5 ENCODE dbSUPER 23.2 +530.1 530107 6 MLX ZFP64 DMAP1 YY1 ZNF143 NFYC ZC3H11A MEF2D SSRP1 ZNF585B ZNF767P ENSG00000244151 REPIN1 NUB1 ZNF777 ATP6V0E2-AS1 ZNF862 ENSG00000273419 ASIC3 ENSG00000243433
GH07H149690 1.4 Ensembl ENCODE 17 -147.4 -147358 1 PKNOX1 FOXA2 ARNT ARID4B SIN3A FEZF1 ZNF2 ZNF416 SP3 ZNF592 ZNF783 ZNF777 ZNF398 ENSG00000271664 LOC155060 ZNF212 ZNF767P ZNF282 ZNF786 ZNF862
GH07H150375 1.6 Ensembl ENCODE dbSUPER 11.6 +542.7 542701 11 HDGF PKNOX1 FOXA2 ARID4B SIN3A DMAP1 YY1 ZNF766 ZNF143 ZNF207 NUB1 REPIN1 ENSG00000244151 ZNF777 ZNF767P ZNF862 ZBED6CL TMEM176A ACTR3C ENSG00000284048
GH07H150783 1.8 FANTOM5 Ensembl ENCODE dbSUPER 9.8 +948.9 948874 6 PKNOX1 ATF1 ARNT YY1 TCF12 GATA2 ELK1 ATF7 NCOA1 REST TMEM176A TMEM176B AOC1 GIMAP1 ZNF862 GIMAP2 AGAP3 GIMAP8 SMARCD3 SLC4A2
GH07H150356 1.5 Ensembl ENCODE dbSUPER 11.6 +519.8 519847 3 HDGF ARNT YBX1 GLI4 ZNF2 TCF12 ZNF766 ZNF302 ZNF143 FOS NUB1 ENSG00000244151 ZNF767P REPIN1 ZNF777 ABCB8 ZNF775 LOC105375564 ZBED6CL ZNF862
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF862 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF862 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000219655 333 1001 HDGF PKNOX1 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1

Genomic Location for ZNF862 Gene

Chromosome:
7
Start:
149,838,367 bp from pter
End:
149,867,479 bp from pter
Size:
29,113 bases
Orientation:
Plus strand

Genomic View for ZNF862 Gene

Genes around ZNF862 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF862 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF862 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF862 Gene

Proteins for ZNF862 Gene

  • Protein details for ZNF862 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O60290-ZN862_HUMAN
    Recommended name:
    Zinc finger protein 862
    Protein Accession:
    O60290
    Secondary Accessions:
    • A0AUL8

    Protein attributes for ZNF862 Gene

    Size:
    1169 amino acids
    Molecular mass:
    131654 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF862 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF862 Gene

Post-translational modifications for ZNF862 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF862 Gene

No data available for DME Specific Peptides for ZNF862 Gene

Domains & Families for ZNF862 Gene

Gene Families for ZNF862 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF862 Gene

Suggested Antigen Peptide Sequences for ZNF862 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZNF862: view

No data available for UniProtKB/Swiss-Prot for ZNF862 Gene

Function for ZNF862 Gene

Molecular function for ZNF862 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF862 Gene

Gene Ontology (GO) - Molecular Function for ZNF862 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
GO:0046983 protein dimerization activity IEA --
genes like me logo Genes that share ontologies with ZNF862: view

Phenotypes for ZNF862 Gene

genes like me logo Genes that share phenotypes with ZNF862: view

Animal Model Products

CRISPR Products

miRNA for ZNF862 Gene

miRTarBase miRNAs that target ZNF862

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ZNF862
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF862 Gene

Localization for ZNF862 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF862 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF862 gene
Compartment Confidence
nucleus 4
mitochondrion 3
cytosol 2
peroxisome 1
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF862 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF862: view

Pathways & Interactions for ZNF862 Gene

SuperPathways for ZNF862 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF862 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ZNF862: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF862 Gene

Drugs & Compounds for ZNF862 Gene

No Compound Related Data Available

Transcripts for ZNF862 Gene

mRNA/cDNA for ZNF862 Gene

(7) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF862 Gene

Zinc finger protein 862:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ZNF862
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF862 Gene

No ASD Table

Relevant External Links for ZNF862 Gene

GeneLoc Exon Structure for
ZNF862
ECgene alternative splicing isoforms for
ZNF862

Expression for ZNF862 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF862 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF862 Gene:

ZNF862

SOURCE GeneReport for Unigene cluster for ZNF862 Gene:

Hs.731923

Evidence on tissue expression from TISSUES for ZNF862 Gene

  • Nervous system(4.5)
genes like me logo Genes that share expression patterns with ZNF862: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF862 Gene

Orthologs for ZNF862 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF862 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF862 33 34
  • 99.49 (n)
dog
(Canis familiaris)
Mammalia ZNF862 33 34
  • 85.14 (n)
cow
(Bos Taurus)
Mammalia ZNF862 33 34
  • 83.55 (n)
rat
(Rattus norvegicus)
Mammalia Zfp862 33
  • 78.62 (n)
oppossum
(Monodelphis domestica)
Mammalia ZNF862 34
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF862 34
  • 71 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF862 34
  • 25 (a)
OneToOne
Species where no ortholog for ZNF862 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF862 Gene

ENSEMBL:
Gene Tree for ZNF862 (if available)
TreeFam:
Gene Tree for ZNF862 (if available)

Paralogs for ZNF862 Gene

Paralogs for ZNF862 Gene

(1) SIMAP similar genes for ZNF862 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZNF862 Gene

genes like me logo Genes that share paralogs with ZNF862: view

Variants for ZNF862 Gene

Sequence variations from dbSNP and Humsavar for ZNF862 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs563616947 Likely benign 149,848,130(+) CCATC(G/T)GGGCA nc-transcript-variant, reference, missense
rs1000232646 -- 149,855,991(+) GGCTC(A/C)CAATA intron-variant
rs1000487506 -- 149,849,724(+) GAGGC(A/G)TGTGT intron-variant
rs1000558298 -- 149,844,960(+) CAATC(C/T)GGCAG intron-variant
rs1000582694 -- 149,851,075(+) GCAAG(C/G)TTCTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF862 Gene

Variant ID Type Subtype PubMed ID
dgv11717n54 CNV gain 21841781
dgv6751n100 CNV gain 25217958
dgv6752n100 CNV gain 25217958
dgv845n27 CNV gain 19166990
esv1920108 CNV deletion 18987734
esv2735335 CNV deletion 23290073
esv2735336 CNV deletion 23290073
esv2735337 CNV deletion 23290073
esv2759571 CNV gain 17122850
esv3576480 CNV gain 25503493
esv3615438 CNV gain 21293372
esv3891234 CNV gain 25118596
nsv1029484 CNV gain 25217958
nsv1033095 CNV gain 25217958
nsv1149876 CNV deletion 26484159
nsv1161666 CNV duplication 26073780
nsv365614 CNV deletion 16902084
nsv469576 CNV loss 16826518
nsv517242 CNV loss 19592680
nsv519323 CNV loss 19592680
nsv521861 CNV loss 19592680
nsv608987 CNV loss 21841781
nsv8229 CNV gain+loss 18304495
nsv831184 CNV gain 17160897
nsv831185 CNV gain 17160897

Variation tolerance for ZNF862 Gene

Residual Variation Intolerance Score: 86.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.13; 80.65% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF862 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF862

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF862 Gene

Disorders for ZNF862 Gene

Relevant External Links for ZNF862

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF862

No disorders were found for ZNF862 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF862 Gene

Publications for ZNF862 Gene

  1. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9628581) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1998) 3 4 60
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 60
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 60
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60
  5. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier LW … Wilson RK (Nature 2003) 4 60

Products for ZNF862 Gene

Sources for ZNF862 Gene

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