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Aliases for ZNF860 Gene

Aliases for ZNF860 Gene

  • Zinc Finger Protein 860 2 3

External Ids for ZNF860 Gene

Summaries for ZNF860 Gene

GeneCards Summary for ZNF860 Gene

ZNF860 (Zinc Finger Protein 860) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF816.

UniProtKB/Swiss-Prot for ZNF860 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF860 Gene

Genomics for ZNF860 Gene

Genomic Location for ZNF860 Gene

Start:
31,981,771 bp from pter
End:
31,991,736 bp from pter
Size:
9,966 bases
Orientation:
Plus strand

Genomic View for ZNF860 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF860 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF860 Gene

Regulatory Elements for ZNF860 Gene

Proteins for ZNF860 Gene

  • Protein details for ZNF860 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NHJ4-ZN860_HUMAN
    Recommended name:
    Zinc finger protein 860
    Protein Accession:
    A6NHJ4
    Secondary Accessions:
    • B4DFA4

    Protein attributes for ZNF860 Gene

    Size:
    632 amino acids
    Molecular mass:
    73757 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF860 Gene

Proteomics data for ZNF860 Gene at MOPED

Post-translational modifications for ZNF860 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF860 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF860 Gene

Domains for ZNF860 Gene

Gene Families for ZNF860 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF860 Gene

Suggested Antigen Peptide Sequences for ZNF860 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NHJ4

UniProtKB/Swiss-Prot:

ZN860_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • A6NHJ4
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • A6NHJ4
Similarity:
  • Contains 14 C2H2-type zinc fingers.:
    • A6NHJ4
genes like me logo Genes that share domains with ZNF860: view

Function for ZNF860 Gene

Molecular function for ZNF860 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF860 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF860: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF860 Gene

Localization for ZNF860 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF860 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF860 Gene COMPARTMENTS Subcellular localization image for ZNF860 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF860 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF860: view

Pathways for ZNF860 Gene

SuperPathways for ZNF860 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF860: view

Pathways by source for ZNF860 Gene

2 Reactome pathways for ZNF860 Gene

Interacting Proteins for ZNF860 Gene

Gene Ontology (GO) - Biological Process for ZNF860 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF860: view

Transcripts for ZNF860 Gene

mRNA/cDNA for ZNF860 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF860 Gene

Zinc finger protein 860:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF860 Gene

No ASD Table

Relevant External Links for ZNF860 Gene

GeneLoc Exon Structure for
ZNF860
ECgene alternative splicing isoforms for
ZNF860

Expression for ZNF860 Gene

mRNA expression in normal human tissues for ZNF860 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF860 Gene

This gene is overexpressed in Esophagus - Mucosa (4.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF860 Gene

SOURCE GeneReport for Unigene cluster for ZNF860 Gene Hs.585139

genes like me logo Genes that share expressions with ZNF860: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF860 Gene

Orthologs for ZNF860 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF860 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF860 35
  • 93.99 (n)
  • 89.29 (a)
ZNF860 36
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 43 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 52 (a)
ManyToMany
Species with no ortholog for ZNF860:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF860 Gene

ENSEMBL:
Gene Tree for ZNF860 (if available)
TreeFam:
Gene Tree for ZNF860 (if available)

Paralogs for ZNF860 Gene

Selected SIMAP similar genes for ZNF860 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZNF860 Gene

genes like me logo Genes that share paralogs with ZNF860: view

Variants for ZNF860 Gene

Sequence variations from dbSNP and Humsavar for ZNF860 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs143052719 -- 31,983,887(+) TCATC(G/T)TGCTT intron-variant
rs144047101 -- 31,984,028(+) GTTTT(-/TTTTG)TTTTT intron-variant
rs145467997 -- 31,984,023(+) TTTTT(-/T)GTTTT intron-variant
rs369416472 -- 31,984,027(+) GGTTT(-/TTTTTGTTTTTG)TTTTT intron-variant
rs559768806 -- 31,983,965(+) AGCTG(C/G)AGCAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF860 Gene

Variant ID Type Subtype PubMed ID
nsv876672 CNV Gain 21882294
nsv876676 CNV Gain 21882294
esv2661264 CNV Deletion 23128226
esv2725102 CNV Deletion 23290073
esv2725103 CNV Deletion 23290073

Relevant External Links for ZNF860 Gene

HapMap Linkage Disequilibrium report
ZNF860

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF860 Gene

Disorders for ZNF860 Gene

No disorders were found for ZNF860 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF860 Gene

Publications for ZNF860 Gene

  1. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 3 4
  2. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PMID: 23000965) Povlsen L.K. … Choudhary C. (Nat. Cell Biol. 2012) 3

Products for ZNF860 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF860
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF860
    • Block miRNA regulation of ZNF860 using miScript Target Protectors

    Sources for ZNF860 Gene

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