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Aliases for ZNF853 Gene

Aliases for ZNF853 Gene

  • Zinc Finger Protein 853 2 3 5

External Ids for ZNF853 Gene

Previous GeneCards Identifiers for ZNF853 Gene

  • GC07P006649
  • GC07P006621
  • GC07P006656
  • GC07P006657
  • GC07P006661

Summaries for ZNF853 Gene

GeneCards Summary for ZNF853 Gene

ZNF853 (Zinc Finger Protein 853) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF787.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF853 Gene

Genomics for ZNF853 Gene

Regulatory Elements for ZNF853 Gene

Enhancers for ZNF853 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F006701 0.8 FANTOM5 1.3 +86.5 86541 0.4 ZNF547 TARDBP C7orf26 ENSG00000198580 ZNF12 ENSG00000232581 ZDHHC4 CCZ1B ZNF853 PIR31984
GH07F006614 0.6 ENCODE 0.8 -0.1 -100 1.9 ELF3 KLF17 ARID4B THRB ZNF48 ZNF2 RARA GLIS2 THAP11 MXD4 ZDHHC4 CCZ1 ZNF853 GC07M006567
GH07F006613 0.2 ENCODE 0.8 -1.6 -1633 0.2 GATA3 GLIS1 THRB RAD21 ZNF853 GC07M006567
GH07F006620 1.1 Ensembl ENCODE 0.4 +5.6 5584 1.6 SCRT1 CTCF CEBPB CEBPG EP300 CTBP1 SCRT2 ZNF341 ZNF169 ZNF207 ZDHHC4 ZNF853 ZNF316
GH07F006623 1.1 Ensembl ENCODE 0.4 +8.6 8608 1.2 POLR2A NRF1 ZNF512 MAX REST PRDM1 ZDHHC4 CCZ1B ZNF853 ZNF316
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZNF853 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF853 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000621612 183 1600 ELF3 KLF17 ARID4B THRB ZNF48 ZNF2 RARA GLIS2 MIXL1 THAP11

Genomic Location for ZNF853 Gene

6,615,617 bp from pter
6,624,290 bp from pter
8,674 bases
Plus strand

Genomic View for ZNF853 Gene

Genes around ZNF853 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF853 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF853 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF853 Gene

Proteins for ZNF853 Gene

  • Protein details for ZNF853 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 853
    Protein Accession:

    Protein attributes for ZNF853 Gene

    659 amino acids
    Molecular mass:
    74878 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF853 Gene

Post-translational modifications for ZNF853 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF853 Gene

No data available for DME Specific Peptides for ZNF853 Gene

Domains & Families for ZNF853 Gene

Gene Families for ZNF853 Gene

Protein Domains for ZNF853 Gene

Suggested Antigen Peptide Sequences for ZNF853 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 5 C2H2-type zinc fingers.
  • Contains 5 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF853: view

Function for ZNF853 Gene

Gene Ontology (GO) - Molecular Function for ZNF853 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF853: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF853 Gene

Localization for ZNF853 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ZNF853 Gene

Pathways & Interactions for ZNF853 Gene

SuperPathways for ZNF853 Gene

No Data Available

Interacting Proteins for ZNF853 Gene

Gene Ontology (GO) - Biological Process for ZNF853 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZNF853 Gene

Transcripts for ZNF853 Gene

mRNA/cDNA for ZNF853 Gene

Unigene Clusters for ZNF853 Gene

Zinc finger protein 853:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF853 Gene

No ASD Table

Relevant External Links for ZNF853 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF853 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF853 Gene

Protein differential expression in normal tissues from HIPED for ZNF853 Gene

This gene is overexpressed in Heart (59.7) and CD8 Tcells (9.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF853 Gene

Protein tissue co-expression partners for ZNF853 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF853 Gene:


SOURCE GeneReport for Unigene cluster for ZNF853 Gene:

genes like me logo Genes that share expression patterns with ZNF853: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF853 Gene

Orthologs for ZNF853 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF853 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ZNF853 35
  • 45 (a)
(Mus musculus)
Mammalia Zfp853 35
  • 39 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 13 (a)
(Danio rerio)
Actinopterygii ZNF787 35
  • 31 (a)
fruit fly
(Drosophila melanogaster)
Insecta pho 35
  • 7 (a)
phol 35
  • 7 (a)
Species where no ortholog for ZNF853 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF853 Gene

Gene Tree for ZNF853 (if available)
Gene Tree for ZNF853 (if available)

Paralogs for ZNF853 Gene

Paralogs for ZNF853 Gene

genes like me logo Genes that share paralogs with ZNF853: view

Variants for ZNF853 Gene

Sequence variations from dbSNP and Humsavar for ZNF853 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10239018 -- 6,620,309(+) CATTT(A/G)TTTAA intron-variant
rs10254971 -- 6,623,588(+) CCGGG(G/T)CGATG utr-variant-3-prime
rs10270077 -- 6,617,122(+) GGGGG(A/C)CTGTG intron-variant
rs111378599 -- 6,615,547(+) GGGCG(C/G)GCAGG upstream-variant-2KB
rs111494489 -- 6,619,259(+) TTGTT(-/TTTG)TTTGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF853 Gene

Variant ID Type Subtype PubMed ID
dgv1090n67 CNV gain 20364138
dgv11172n54 CNV loss 21841781
dgv11173n54 CNV loss 21841781
esv1914954 OTHER inversion 16254605
nsv1020236 CNV gain 25217958
nsv436904 CNV insertion 17901297
nsv508444 CNV deletion 20534489
nsv515978 CNV loss 19592680
nsv606003 CNV loss 21841781
nsv606006 CNV loss 21841781
nsv7392 OTHER inversion 18451855
nsv830895 CNV loss 17160897
nsv950804 CNV deletion 24416366

Variation tolerance for ZNF853 Gene

Gene Damage Index Score: 5.62; 72.59% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF853 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF853 Gene

Disorders for ZNF853 Gene

Relevant External Links for ZNF853

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF853 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF853 Gene

Publications for ZNF853 Gene

  1. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4 64
  2. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 3 64

Products for ZNF853 Gene

Sources for ZNF853 Gene

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