ZNF853 Gene
protein-coding GIFtS: 35
GCID: GC07P006657
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zinc finger protein 853
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Aliases
for ZNF853 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 8531 2 | | DKFZp434J10151 |
Export aliases for ZNF853 gene to outside databasesPrevious GC identifers: GC07P006649 GC07P006621 GC07P006656 |
Summaries
for ZNF853 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ZNF853 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF853 gene promoter:
NF-1 AML1a Tal-1 Pax-5 Lmo2 Zic3 E47 c-Ets-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF853
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF853 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7p22.1 Ensembl cytogenetic band: 7p22.1 HGNC cytogenetic band: 7p22.1ZNF853 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P006657: view genomic region
(about GC identifiers)
Start:
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6,655,248 bp from pter |
End:
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6,663,921 bp from pter |
Size:
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8,674 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 6,702,580-6,710,967 |
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Proteins
for ZNF853 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN853_HUMAN, P0CG23 (See
protein sequence)Recommended Name: Zinc finger protein 853 Size: 659 amino acids; 74878 DaExplore the universe of human proteins at neXtProt for ZNF853: NX_P0CG23
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P0CG23
ZNF853 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_060030.1
ENSEMBL proteins: ENSP00000455585
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005622 | intracellular |
IEA | -- |
ZNF853 for ontologies About GeneDecksing
ZNF853 Antibody Products:
Assay Products for ZNF853: |
Protein
Domains /
Families
for ZNF853 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF853 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P0CG23ProtoNet protein and cluster: P0CG23 UniProtKB/Swiss-Prot: ZN853_HUMAN, P0CG23Similarity: Contains 5 C2H2-type zinc fingers |
Function
for ZNF853 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF853
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF853
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF853 (NM_017560) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF853 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF853 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF853 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003676 | nucleic acid binding |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
ZNF853 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF853 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF853
|
Drugs & Compounds
for ZNF853 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF853
Search CenterWatch for drugs/clinical trials and news about ZNF853 / ZN853
|
Transcripts
for ZNF853 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF853 gene: NM_017560.1 Unigene Cluster for ZNF853: Zinc finger protein 853 Hs.592170 [show with all ESTs]Unigene Representative Sequence: NM_0175601 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000457543(uc011jwz.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF853
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF853
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF853 (NM_017560) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF853 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF853 |
Additional cDNA sequence: AL133055.1 AL390175.1 5 DOTS entries: DT.443530 DT.40223642 DT.92005216 DT.100800875 DT.120808118 24/54 AceView cDNA sequences (see all 54): CD674236 BQ940467 AI095022 BE220037 BF437357 AL133055 BX282720 AW475080 BG056932 BM141884 AI138531 BF527438 AW615734 BQ069840 AL390175 BF204282 CK906091 BM997805 AW026444 CA418704 AL048863 AW874500 BM930152 AW264366
GeneLoc Exon Structure
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Expression
for ZNF853 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF853 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTTGGTAAG
About this image
Genevestigator expression for ZNF853
SOURCE GeneReport for Unigene cluster: Hs.592170
SABiosciences Custom PCR Arrays for ZNF853
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF853
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF853 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF853 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF853 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF853 |
Orthologs
for ZNF853 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZNF853 gene from 3/15 species (see all 15) About this table
ENSEMBL Gene Tree for ZNF853 (if available)
TreeFam Gene Tree for ZNF853 (if available) |
Paralogs
for ZNF853 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF853 gene
- IVL2
18/135 SIMAP similar genes for ZNF853 using alignment to 2 protein entries: ZN853_HUMAN (see all proteins)
(see all similar genes):ZFS-4 ZNF818P ZNF154 DKFZp666C237 ZNF514 ZNF586
ZNF697 DKFZp686O111 GLI4 ZFS-5 ZNF78L1 HZF36
ZNF146 ZNF260 ZNF35 ZNF570 ZNF585B ZNF662
ZNF853 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF853 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF853 (6655248 - 6663921 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF853
1 Inversion: 37290 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for ZNF853 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF853 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF853 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF853) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)1 Dephoure N.... Gygi S.P. (2008)
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External Searches for ZNF853 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ZNF853 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF853 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF853 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF853 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF853 gene:
Search GeneIP for patents involving ZNF853
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF853 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF853 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF853 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF853 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for ZNF853 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF853 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF853 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF853 | | OriGene Custom Protein Services for ZNF853 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF853 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF853 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF853 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF853 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF853 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF853 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZNF853 |
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 | | | ZNF853 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF853 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF853 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF853 |
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