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Aliases for ZNF852 Gene

Aliases for ZNF852 Gene

  • Zinc Finger Protein 852 2 3 5

External Ids for ZNF852 Gene

Previous GeneCards Identifiers for ZNF852 Gene

  • GC03P044513
  • GC03M044517

Summaries for ZNF852 Gene

GeneCards Summary for ZNF852 Gene

ZNF852 (Zinc Finger Protein 852) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZKSCAN7.

UniProtKB/Swiss-Prot for ZNF852 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF852 Gene

Genomics for ZNF852 Gene

Regulatory Elements for ZNF852 Gene

Enhancers for ZNF852 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F044532 0.2 ENCODE 12.1 -22.4 -22364 0.2 ARNT MLX ZFP64 ARID4B DMAP1 ZNF48 ZNF2 SLC30A9 ELK1 CBX5 ZNF197 ZNF852 ZKSCAN7 TGM4 ENSG00000235845 ZNF445 ZNF660 ZNF501 CLEC3B RNU5B-3P
GH03F044451 0.2 ENCODE 11.3 +58.9 58943 1.1 ZNF445 ZNF852 GC03M044441
GH03F044341 1 Ensembl ENCODE 10.5 +168.2 168247 1.2 HLF CEBPB ZNF660 ZNF852 ZNF445 ZKSCAN7 ZNF197 LOC105377055 LINC01988
GH03F044509 0.2 ENCODE 0.8 -0.1 -60 2.6 HDGF ATF1 ARNT WRNIP1 ARID4B ZNF48 ZNF2 ZNF143 ZNF207 NCOA1 ZNF660 ZNF197 ZNF852 EI24P3
GH03F044518 0.9 Ensembl ENCODE 0.4 -7.8 -7761 0.4 PKNOX1 ATF1 ARNT ELK1 GATA2 NCOA1 REST CREB3 MBD2 MEF2D EI24P3 ZNF852
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZNF852 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF852 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001362492 -60 2201 HDGF ARNT WRNIP1 ARID4B ZNF48 ZNF2 ZNF143 ZNF207 NCOA1 SMARCA4

Genomic Location for ZNF852 Gene

Chromosome:
3
Start:
44,498,970 bp from pter
End:
44,510,640 bp from pter
Size:
11,671 bases
Orientation:
Minus strand

Genomic View for ZNF852 Gene

Genes around ZNF852 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF852 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF852 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF852 Gene

Proteins for ZNF852 Gene

  • Protein details for ZNF852 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZMS4-ZN852_HUMAN
    Recommended name:
    Zinc finger protein 852
    Protein Accession:
    Q6ZMS4
    Secondary Accessions:
    • B4DLD7

    Protein attributes for ZNF852 Gene

    Size:
    543 amino acids
    Molecular mass:
    62084 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAG59499.1; Type=Frameshift; Positions=494, 534; Evidence={ECO:0000305};

neXtProt entry for ZNF852 Gene

Post-translational modifications for ZNF852 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF852 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF852 Gene

Domains & Families for ZNF852 Gene

Gene Families for ZNF852 Gene

Protein Domains for ZNF852 Gene

Suggested Antigen Peptide Sequences for ZNF852 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZMS4

UniProtKB/Swiss-Prot:

ZN852_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF852: view

Function for ZNF852 Gene

Molecular function for ZNF852 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF852 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF852: view

Phenotypes for ZNF852 Gene

GenomeRNAi human phenotypes for ZNF852:
genes like me logo Genes that share phenotypes with ZNF852: view

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF852 Gene

Localization for ZNF852 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF852 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF852 Gene COMPARTMENTS Subcellular localization image for ZNF852 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF852 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF852: view

Pathways & Interactions for ZNF852 Gene

SuperPathways for ZNF852 Gene

No Data Available

Interacting Proteins for ZNF852 Gene

Gene Ontology (GO) - Biological Process for ZNF852 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF852: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF852 Gene

Transcripts for ZNF852 Gene

mRNA/cDNA for ZNF852 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(15) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF852 Gene

Zinc finger protein 852:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF852 Gene

No ASD Table

Relevant External Links for ZNF852 Gene

GeneLoc Exon Structure for
ZNF852
ECgene alternative splicing isoforms for
ZNF852

Expression for ZNF852 Gene

mRNA expression in normal human tissues for ZNF852 Gene

Protein differential expression in normal tissues from HIPED for ZNF852 Gene

This gene is overexpressed in Spinal cord (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF852 Gene



Protein tissue co-expression partners for ZNF852 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF852 Gene:

ZNF852

SOURCE GeneReport for Unigene cluster for ZNF852 Gene:

Hs.648974
genes like me logo Genes that share expression patterns with ZNF852: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF852 Gene

Orthologs for ZNF852 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF852 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ZNF852 34 35
  • 85.8 (n)
cow
(Bos Taurus)
Mammalia ZKSCAN7 34
  • 84.61 (n)
-- 35
  • 52 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 54 (a)
ManyToMany
-- 35
  • 51 (a)
ManyToMany
-- 35
  • 48 (a)
ManyToMany
-- 35
  • 36 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zkscan7 35
  • 47 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 44 (a)
OneToMany
Species where no ortholog for ZNF852 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF852 Gene

ENSEMBL:
Gene Tree for ZNF852 (if available)
TreeFam:
Gene Tree for ZNF852 (if available)

Paralogs for ZNF852 Gene

(528) SIMAP similar genes for ZNF852 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZNF852 Gene

genes like me logo Genes that share paralogs with ZNF852: view

Variants for ZNF852 Gene

Sequence variations from dbSNP and Humsavar for ZNF852 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs111270702 -- 44,507,473(+) CACGC(C/G)CGGCT intron-variant
rs111724074 -- 44,510,578(+) AATCA(C/T)CCAAA utr-variant-5-prime
rs111987500 -- 44,502,303(+) CTCTA(A/C)CTAAA intron-variant
rs112137920 -- 44,509,771(+) CAGAA(A/G)GCTGA intron-variant
rs112151014 -- 44,508,287(+) AAGAA(A/G)AAAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF852 Gene

Variant ID Type Subtype PubMed ID
esv2725213 CNV deletion 23290073
nsv965161 CNV duplication 23825009

Variation tolerance for ZNF852 Gene

Gene Damage Index Score: 1.32; 26.19% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF852 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF852

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF852 Gene

Disorders for ZNF852 Gene

Relevant External Links for ZNF852

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF852

No disorders were found for ZNF852 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF852 Gene

Publications for ZNF852 Gene

  1. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64
  2. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ZNF852 Gene

Sources for ZNF852 Gene

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