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Aliases for ZNF846 Gene

Aliases for ZNF846 Gene

  • Zinc Finger Protein 846 2 3 5

External Ids for ZNF846 Gene

Previous GeneCards Identifiers for ZNF846 Gene

  • GC19M009868
  • GC19M009449

Summaries for ZNF846 Gene

GeneCards Summary for ZNF846 Gene

ZNF846 (Zinc Finger Protein 846) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF562.

UniProtKB/Swiss-Prot for ZNF846 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF846 Gene

Genomics for ZNF846 Gene

Regulatory Elements for ZNF846 Gene

Enhancers for ZNF846 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF846 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF846 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF846 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF846 Gene

9,751,993 bp from pter
9,793,180 bp from pter
41,188 bases
Minus strand

Genomic View for ZNF846 Gene

Genes around ZNF846 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF846 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF846 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF846 Gene

Proteins for ZNF846 Gene

  • Protein details for ZNF846 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 846
    Protein Accession:
    Secondary Accessions:
    • A8K0H1
    • B3KUP1

    Protein attributes for ZNF846 Gene

    533 amino acids
    Molecular mass:
    60552 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF846 Gene


neXtProt entry for ZNF846 Gene

Proteomics data for ZNF846 Gene at MOPED

Post-translational modifications for ZNF846 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF846 Gene

Domains & Families for ZNF846 Gene

Gene Families for ZNF846 Gene

Protein Domains for ZNF846 Gene

Suggested Antigen Peptide Sequences for ZNF846 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 14 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF846: view

Function for ZNF846 Gene

Molecular function for ZNF846 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF846: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF846 Gene

Localization for ZNF846 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF846 Gene

Subcellular locations from

Jensen Localization Image for ZNF846 Gene COMPARTMENTS Subcellular localization image for ZNF846 gene
Compartment Confidence
nucleus 5
cytoskeleton 2
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF846 Gene

Pathways & Interactions for ZNF846 Gene

SuperPathways for ZNF846 Gene

No Data Available

Interacting Proteins for ZNF846 Gene

Gene Ontology (GO) - Biological Process for ZNF846 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZNF846 Gene

Drugs & Compounds for ZNF846 Gene

No Compound Related Data Available

Transcripts for ZNF846 Gene

Unigene Clusters for ZNF846 Gene

Zinc finger protein 846:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF846 Gene

No ASD Table

Relevant External Links for ZNF846 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF846 Gene

mRNA expression in normal human tissues for ZNF846 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF846 Gene

SOURCE GeneReport for Unigene cluster for ZNF846 Gene Hs.665717

genes like me logo Genes that share expression patterns with ZNF846: view

Protein tissue co-expression partners for ZNF846 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF846 Gene

Orthologs for ZNF846 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF846 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ZNF846 35
  • 78.18 (n)
  • 66.59 (a)
(Mus musculus)
Mammalia Zfp846 35
  • 64.77 (n)
  • 53.62 (a)
Zfp846 16
(Pan troglodytes)
Mammalia ZNF846 35
  • 99.44 (n)
  • 98.5 (a)
ZNF846 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Zfp846 35
  • 64.77 (n)
  • 53.23 (a)
Species with no ortholog for ZNF846:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF846 Gene

Gene Tree for ZNF846 (if available)
Gene Tree for ZNF846 (if available)

Paralogs for ZNF846 Gene

Paralogs for ZNF846 Gene

(506) SIMAP similar genes for ZNF846 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF846: view

Variants for ZNF846 Gene

Sequence variations from dbSNP and Humsavar for ZNF846 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10414485 - 9,757,728(+) ATTCA(A/C/T)AGGCC intron-variant, nc-transcript-variant, reference, missense
rs10420364 - 9,757,602(+) TAAGG(C/T)ATGTG intron-variant, nc-transcript-variant, reference, missense
rs7260256 -- 9,771,780(+) ttttt(C/T)ttttt intron-variant
rs12979092 -- 9,779,429(+) acgcc(C/T)ggcta intron-variant
rs12982707 -- 9,783,524(+) tcatc(A/C)ctaaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF846 Gene

Variant ID Type Subtype PubMed ID
nsv518826 CNV Loss 19592680
nsv2413 CNV Loss 18451855
nsv514908 CNV Loss 21397061
esv22853 CNV Loss 19812545
esv2675791 CNV Deletion 23128226
nsv498892 CNV Loss 21111241

Variation tolerance for ZNF846 Gene

Residual Variation Intolerance Score: 85.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.76; 78.93% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF846 Gene

Disorders for ZNF846 Gene

Relevant External Links for ZNF846

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF846 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF846 Gene

Publications for ZNF846 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett E.J. … Harper J.W. (Cell 2010) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF846 Gene

Sources for ZNF846 Gene