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Aliases for ZNF846 Gene

Aliases for ZNF846 Gene

  • Zinc Finger Protein 846 2 3

External Ids for ZNF846 Gene

Summaries for ZNF846 Gene

GeneCards Summary for ZNF846 Gene

ZNF846 (Zinc Finger Protein 846) is a Protein Coding gene. An important paralog of this gene is ZNF426.

UniProtKB/Swiss-Prot for ZNF846 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF846 Gene

Genomics for ZNF846 Gene

Genomic Location for ZNF846 Gene

Start:
9,751,993 bp from pter
End:
9,793,180 bp from pter
Size:
41,188 bases
Orientation:
Minus strand

Genomic View for ZNF846 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF846 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF846 Gene

Regulatory Elements for ZNF846 Gene

Proteins for ZNF846 Gene

  • Protein details for ZNF846 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q147U1-ZN846_HUMAN
    Recommended name:
    Zinc finger protein 846
    Protein Accession:
    Q147U1
    Secondary Accessions:
    • A8K0H1
    • B3KUP1

    Protein attributes for ZNF846 Gene

    Size:
    533 amino acids
    Molecular mass:
    60552 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF846 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF846 Gene

Proteomics data for ZNF846 Gene at MOPED

Post-translational modifications for ZNF846 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF846 Gene

Domains for ZNF846 Gene

Gene Families for ZNF846 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF846 Gene

UniProtKB/Swiss-Prot:

ZN846_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q147U1
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q147U1
Similarity:
  • Contains 14 C2H2-type zinc fingers.:
    • Q147U1
genes like me logo Genes that share domains with ZNF846: view

Function for ZNF846 Gene

Molecular function for ZNF846 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF846 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF846: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF846 Gene

Localization for ZNF846 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF846 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF846 Gene COMPARTMENTS Subcellular localization image for ZNF846 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF846 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF846: view

Pathways for ZNF846 Gene

SuperPathways for ZNF846 Gene

No Data Available

Interacting Proteins for ZNF846 Gene

Gene Ontology (GO) - Biological Process for ZNF846 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF846: view

No data available for Pathways by source for ZNF846 Gene

Transcripts for ZNF846 Gene

Unigene Clusters for ZNF846 Gene

Zinc finger protein 846:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF846 Gene

No ASD Table

Relevant External Links for ZNF846 Gene

GeneLoc Exon Structure for
ZNF846
ECgene alternative splicing isoforms for
ZNF846

Expression for ZNF846 Gene

mRNA expression in normal human tissues for ZNF846 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF846 Gene

SOURCE GeneReport for Unigene cluster for ZNF846 Gene Hs.665717

genes like me logo Genes that share expressions with ZNF846: view

Orthologs for ZNF846 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF846 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF846 36
  • 99.44 (n)
  • 98.5 (a)
ZNF846 37
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF846 36
  • 78.18 (n)
  • 66.59 (a)
mouse
(Mus musculus)
Mammalia Zfp846 36
  • 64.77 (n)
  • 53.62 (a)
Zfp846 16
rat
(Rattus norvegicus)
Mammalia Zfp846 36
  • 64.77 (n)
  • 53.23 (a)
Species with no ortholog for ZNF846:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF846 Gene

ENSEMBL:
Gene Tree for ZNF846 (if available)
TreeFam:
Gene Tree for ZNF846 (if available)

Paralogs for ZNF846 Gene

Paralogs for ZNF846 Gene

Selected SIMAP similar genes for ZNF846 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF846: view

Variants for ZNF846 Gene

Sequence variations from dbSNP and Humsavar for ZNF846 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs964474 -- 9,752,139(-) GTCAC(A/G)TGTAT downstream-variant-500B
rs969507 -- 9,782,529(-) tccca(G/T)tgctt intron-variant
rs969508 -- 9,782,379(-) gctga(A/G)gctgg intron-variant
rs1007550 -- 9,768,596(-) CTGCT(A/G)GGTCT utr-variant-5-prime, intron-variant, nc-transcript-variant
rs1559197 -- 9,762,827(-) acttt(C/T)ttaaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF846 Gene

Variant ID Type Subtype PubMed ID
nsv518826 CNV Loss 19592680
nsv2413 CNV Loss 18451855
nsv514908 CNV Loss 21397061
esv22853 CNV Loss 19812545
esv2675791 CNV Deletion 23128226
nsv498892 CNV Loss 21111241

Relevant External Links for ZNF846 Gene

HapMap Linkage Disequilibrium report
ZNF846

Disorders for ZNF846 Gene

No disorders were found for ZNF846 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF846 Gene

Publications for ZNF846 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett E.J. … Harper J.W. (Cell 2010) 3
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for ZNF846 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF846
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF846
    • Block miRNA regulation of ZNF846 using miScript Target Protectors

    Sources for ZNF846 Gene

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