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Aliases for ZNF845 Gene

Aliases for ZNF845 Gene

  • Zinc Finger Protein 845 2 3 5

External Ids for ZNF845 Gene

Previous GeneCards Identifiers for ZNF845 Gene

  • GC19P058546
  • GC19P053837
  • GC19P050157

Summaries for ZNF845 Gene

GeneCards Summary for ZNF845 Gene

ZNF845 (Zinc Finger Protein 845) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF808.

UniProtKB/Swiss-Prot for ZNF845 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF845 Gene

Genomics for ZNF845 Gene

Regulatory Elements for ZNF845 Gene

Enhancers for ZNF845 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G053864 1.8 FANTOM5 ENCODE dbSUPER 21.8 +535.2 535201 9.8 MLX CREB3L1 AGO1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 ZNF845 ZNF765 ZNF816 ENSG00000269001 ENSG00000235681 ZNF813 TPM3P6 LENG8-AS1 MYADM ZNF525
GH19G053977 1.3 Ensembl ENCODE 23.5 +646.2 646248 5.8 HDGF PKNOX1 CREB3L1 SIN3A FEZF1 ZNF2 ZNF766 ZNF143 ZNF263 SP3 ZNF665 PRPF31 ZNF347 ZNF845 ZNF525 LENG8-AS1 ZNF702P CACNG8 TPM3P9 TPM3P6
GH19G053907 1.5 FANTOM5 Ensembl ENCODE 16.6 +575.6 575574 2.6 CREB3L1 ZNF133 ZNF76 DEAF1 GLI4 YBX1 ZNF48 ETS1 ZNF766 ZNF143 PRKCG ZNF845 ENSG00000235681 ZNF665 LENG8-AS1 ZNF347 ENSG00000232220 LOC105372457 PRPF31 ZNF765
GH19G053594 1.1 ENCODE dbSUPER 22.5 +259.5 259515 0.0 ARNT GLI4 ZNF48 ZBTB40 ZEB1 ZNF335 ZNF366 EGR1 KLF7 EGR2 ZNF525 ZNF665 ZNF28 PRPF31 ZNF347 LENG8-AS1 ZNF845 ZNF765 ENSG00000235681 ZNF320
GH19G053595 1.1 ENCODE dbSUPER 22.5 +259.4 259418 0.2 CREB3L1 ARNT GLI4 RAD21 ZNF48 ZBTB40 ZEB1 ZNF335 GLIS2 ZNF366 ZNF525 ZNF28 PRPF31 ZNF665 LENG8-AS1 ZNF845 ZNF765 ENSG00000235681 ZNF677 ENSG00000269825
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF845 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF845 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000111364 -13 2200 ELF3 HDGF HDAC1 PKNOX1 ARID4B ZNF76 SIN3A ZNF48 GATA4 ZNF366

Transcription factor binding sites by QIAGEN in the ZNF845 gene promoter:

Genomic Location for ZNF845 Gene

Chromosome:
19
Start:
53,333,714 bp from pter
End:
53,354,869 bp from pter
Size:
21,156 bases
Orientation:
Plus strand

Genomic View for ZNF845 Gene

Genes around ZNF845 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF845 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF845 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF845 Gene

Proteins for ZNF845 Gene

  • Protein details for ZNF845 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96IR2-ZN845_HUMAN
    Recommended name:
    Zinc finger protein 845
    Protein Accession:
    Q96IR2

    Protein attributes for ZNF845 Gene

    Size:
    970 amino acids
    Molecular mass:
    113133 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF845 Gene

Post-translational modifications for ZNF845 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF845 Gene

No data available for DME Specific Peptides for ZNF845 Gene

Domains & Families for ZNF845 Gene

Gene Families for ZNF845 Gene

Protein Domains for ZNF845 Gene

Suggested Antigen Peptide Sequences for ZNF845 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96IR2

UniProtKB/Swiss-Prot:

ZN845_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF845: view

Function for ZNF845 Gene

Molecular function for ZNF845 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF845 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF845: view
genes like me logo Genes that share phenotypes with ZNF845: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF845 Gene

Localization for ZNF845 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF845 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF845 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF845 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF845: view

Pathways & Interactions for ZNF845 Gene

SuperPathways for ZNF845 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF845 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF845: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF845 Gene

Transcripts for ZNF845 Gene

mRNA/cDNA for ZNF845 Gene

(4) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(12) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF845 Gene

Zinc finger protein 845:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF845 Gene

No ASD Table

Relevant External Links for ZNF845 Gene

GeneLoc Exon Structure for
ZNF845
ECgene alternative splicing isoforms for
ZNF845

Expression for ZNF845 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF845 Gene

Protein differential expression in normal tissues from HIPED for ZNF845 Gene

This gene is overexpressed in Placenta (58.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF845 Gene



Protein tissue co-expression partners for ZNF845 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF845 Gene:

ZNF845

SOURCE GeneReport for Unigene cluster for ZNF845 Gene:

Hs.720672

Evidence on tissue expression from TISSUES for ZNF845 Gene

  • Nervous system(4.2)
  • Eye(4.1)
genes like me logo Genes that share expression patterns with ZNF845: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF845 Gene

Orthologs for ZNF845 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF845 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF845 34 35
  • 99.07 (n)
rat
(Rattus norvegicus)
Mammalia LOC102548633 34
  • 61.99 (n)
mouse
(Mus musculus)
Mammalia LOC101055890 34
  • 61.39 (n)
Gm4944 35
  • 50 (a)
ManyToMany
Gm31526 16
cow
(Bos Taurus)
Mammalia -- 35
  • 44 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 48 (a)
ManyToMany
-- 35
  • 46 (a)
ManyToMany
-- 35
  • 41 (a)
ManyToMany
-- 35
  • 41 (a)
ManyToMany
-- 35
  • 36 (a)
ManyToMany
CSA.1668 35
  • 36 (a)
ManyToMany
Species where no ortholog for ZNF845 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF845 Gene

ENSEMBL:
Gene Tree for ZNF845 (if available)
TreeFam:
Gene Tree for ZNF845 (if available)

Paralogs for ZNF845 Gene

(531) SIMAP similar genes for ZNF845 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZNF845 Gene

genes like me logo Genes that share paralogs with ZNF845: view

Variants for ZNF845 Gene

Sequence variations from dbSNP and Humsavar for ZNF845 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000033558 -- 53,353,557(+) ACGTC(A/C)TCATA reference, missense
rs1000140526 -- 53,351,132(+) TCCAC(A/T)TGTTT reference, missense
rs1000231534 -- 53,346,666(+) ACAGA(A/G)CGACA intron-variant
rs1000374760 -- 53,343,039(+) GTCTT(A/G)AACTC intron-variant
rs1000389940 -- 53,342,280(+) CGGAT(A/G)ATTTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF845 Gene

Variant ID Type Subtype PubMed ID
dgv670e214 CNV loss 21293372
esv2670793 CNV deletion 23128226
esv2718787 CNV deletion 23290073
esv2718812 CNV deletion 23290073
esv2718816 CNV deletion 23290073
esv3644750 CNV gain 21293372
nsv1055773 CNV gain 25217958
nsv1078889 OTHER inversion 25765185
nsv1141887 OTHER inversion 24896259
nsv580080 CNV loss 21841781
nsv978846 CNV duplication 23825009

Variation tolerance for ZNF845 Gene

Residual Variation Intolerance Score: 93% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.24; 76.21% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF845 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF845

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF845 Gene

Disorders for ZNF845 Gene

Relevant External Links for ZNF845

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF845

No disorders were found for ZNF845 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF845 Gene

Publications for ZNF845 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 64
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ZNF845 Gene

Sources for ZNF845 Gene

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