ZNF845 Gene
protein-coding GIFtS: 33
GCID: GC19P053837
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zinc finger protein 845
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Aliases
for ZNF845 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 8451 2 |
Export aliases for ZNF845 gene to outside databasesPrevious GC identifers: GC19P058546 GC19P050157 |
Summaries
for ZNF845 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN845_HUMAN, Q96IR2Function: May be involved in transcriptional regulation (By similarity)
|
Genomic Views
for ZNF845 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF845 gene promoter:
AREB6 C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF845
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF845 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.42 Ensembl cytogenetic band: 19q13.42 HGNC cytogenetic band: 19q13.42ZNF845 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P053837: view genomic region
(about GC identifiers)
Start:
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53,837,002 bp from pter |
End:
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53,858,122 bp from pter |
Size:
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21,121 bases |
Orientation:
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plus strand |
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Proteins
for ZNF845 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN845_HUMAN, Q96IR2 (See
protein sequence)Recommended Name: Zinc finger protein 845 Size: 970 amino acids; 113133 Da
Subcellular location: Nucleus (By similarity)Explore the universe of human proteins at neXtProt for ZNF845: NX_Q96IR2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96IR2
ZNF845 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_612383.1
ENSEMBL proteins: ENSP00000388311
Human Recombinant Protein Products for ZNF845:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF845 for ontologies About GeneDecksing
ZNF845 Antibody Products:
Assay Products for ZNF845: |
Protein
Domains /
Families
for ZNF845 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF845 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96IR2ProtoNet protein and cluster: Q96IR2 UniProtKB/Swiss-Prot: ZN845_HUMAN, Q96IR2Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 27 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF845 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZN845_HUMAN, Q96IR2Function: May be involved in transcriptional regulation (By similarity) Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF845 for ontologies About GeneDecksing
Animal Models:
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF845
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for ZNF845 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF845 |
|
Pathways & Interactions
for ZNF845 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF845
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF845 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF845 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF845
Search CenterWatch for drugs/clinical trials and news about ZNF845 / ZN845
|
Transcripts
for ZNF845 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF845 gene: NM_138374.1 Unigene Cluster for ZNF845: Zinc finger protein 845 Hs.720672 [show with all ESTs]Unigene Representative Sequence: NM_1383741 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000458035(uc010ydv.1 uc010ydw.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF845
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF845
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF845 (NM_138374) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF845 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF845 |
Additional cDNA sequence: AK096653.1 AK295079.1 BC007307.1 9 DOTS entries: DT.91758862 DT.100015972 DT.95132340 DT.102837802 DT.102839353 DT.410283 DT.70104669 DT.92416069 DT.95214051 24/70 AceView cDNA sequences (see all 70): BQ958705 BQ008299 BQ690668 AI953831 BP871716 AI003260 BC067346 CD244192 BX955279 BQ424683 CO249550 NM_152472 BQ023016 NM_018260 BU754034 AL833487 BV193457 CO250069 CO249357 BG324525 AK095562 CR749856 AK001753 AK055946
GeneLoc Exon Structure
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Expression
for ZNF845 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF845 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGTCACTTTT
About this image
See ZNF845 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.720672
SABiosciences Custom PCR Arrays for ZNF845
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF845
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF845 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF845 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF845 |
Orthologs
for ZNF845 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZNF845 gene from 3/13 species (see all 13) About this table
ENSEMBL Gene Tree for ZNF845 (if available)
TreeFam Gene Tree for ZNF845 (if available) |
Paralogs
for ZNF845 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF845 gene
- ZNF6162 ZNF1602 ZNF8502 ZNF992 ZNF5462 ZNF6652 ZNF8362 ZNF7212
- ZNF8412 ZNF912 ZNF432 ZNF780B2 ZNF1972 ZNF585A2 ZNF8082 ZNF7292
- ZNF3472 ZNF1842 ZNF585B2 ZNF6582 ZNF6242 ZNF2082
18/515 SIMAP similar genes for ZNF845 using alignment to 2 protein entries: ZN845_HUMAN (see all proteins)
(see all similar genes):ZNF765 ZNF321P MGC12518 ZNF761 ZNF813 kr-znf3
ZNF468 ZNF701 ZNF137P ZNF611 ZNF738 ZNF78L1
ZNF525 ZNF578 ZNF28 ZNF818P ZNF826P HZF30
ZNF845 for paralogs About GeneDecksing
4 Pseudogenes.org Pseudogenes for ZNF845
PGOHUM00000234399 PGOHUM00000234405 PGOHUM00000250621 PGOHUM00000246026
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Genomic Variants
for ZNF845 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF845 (53837002 - 53858122 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF845: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF845 |
|
Disorders
/ Diseases
for ZNF845 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF845 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF845 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF845) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZNF845 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ZNF845 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF845 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF845 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF845 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ZNF845 gene:
Search GeneIP for patents involving ZNF845
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF845 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
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 | | | ZNF845 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  |  | | | | Search ThermoFisher Antibodies for ZNF845 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF845 |
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