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Aliases for ZNF845 Gene

Aliases for ZNF845 Gene

  • Zinc Finger Protein 845 2 3

External Ids for ZNF845 Gene

Summaries for ZNF845 Gene

GeneCards Summary for ZNF845 Gene

ZNF845 (Zinc Finger Protein 845) is a Protein Coding gene. An important paralog of this gene is ZNF268.

UniProtKB/Swiss-Prot for ZNF845 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF845 Gene

Genomics for ZNF845 Gene

Genomic Location for ZNF845 Gene

Start:
53,333,747 bp from pter
End:
53,354,869 bp from pter
Size:
21,123 bases
Orientation:
Plus strand

Genomic View for ZNF845 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF845 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF845 Gene

Regulatory Elements for ZNF845 Gene

Transcription factor binding sites by QIAGEN in the ZNF845 gene promoter:

Proteins for ZNF845 Gene

  • Protein details for ZNF845 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96IR2-ZN845_HUMAN
    Recommended name:
    Zinc finger protein 845
    Protein Accession:
    Q96IR2
    Secondary Accessions:

    Protein attributes for ZNF845 Gene

    Size:
    970 amino acids
    Molecular mass:
    113133 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF845 Gene

Proteomics data for ZNF845 Gene at MOPED

Post-translational modifications for ZNF845 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys692

Other Protein References for ZNF845 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF845 Gene

Domains for ZNF845 Gene

Gene Families for ZNF845 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF845 Gene

UniProtKB/Swiss-Prot:

ZN845_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q96IR2
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q96IR2
Similarity:
  • Contains 27 C2H2-type zinc fingers.:
    • Q96IR2
genes like me logo Genes that share domains with ZNF845: view

Function for ZNF845 Gene

Molecular function for ZNF845 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF845 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF845: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF845 Gene

Localization for ZNF845 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF845 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF845 Gene COMPARTMENTS Subcellular localization image for ZNF845 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF845 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF845: view

Pathways for ZNF845 Gene

SuperPathways for ZNF845 Gene

No Data Available

Interacting Proteins for ZNF845 Gene

Gene Ontology (GO) - Biological Process for ZNF845 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF845: view

No data available for Pathways by source for ZNF845 Gene

Transcripts for ZNF845 Gene

mRNA/cDNA for ZNF845 Gene

Unigene Clusters for ZNF845 Gene

Zinc finger protein 845:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF845 Gene

No ASD Table

Relevant External Links for ZNF845 Gene

GeneLoc Exon Structure for
ZNF845
ECgene alternative splicing isoforms for
ZNF845

Expression for ZNF845 Gene

mRNA expression in normal human tissues for ZNF845 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF845 Gene

SOURCE GeneReport for Unigene cluster for ZNF845 Gene Hs.720672

genes like me logo Genes that share expressions with ZNF845: view

Orthologs for ZNF845 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF845 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF845 36
  • 99.07 (n)
  • 98.97 (a)
ZNF845 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 44 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm4944 37
  • 50 (a)
ManyToMany
LOC101055890 36
  • 61.39 (n)
  • 56.91 (a)
rat
(Rattus norvegicus)
Mammalia LOC102548633 36
  • 61.99 (n)
  • 54.34 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 41 (a)
ManyToMany
-- 37
  • 36 (a)
ManyToMany
-- 37
  • 48 (a)
ManyToMany
-- 37
  • 41 (a)
ManyToMany
-- 37
  • 46 (a)
ManyToMany
CSA.1668 37
  • 36 (a)
ManyToMany
Species with no ortholog for ZNF845:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF845 Gene

ENSEMBL:
Gene Tree for ZNF845 (if available)
TreeFam:
Gene Tree for ZNF845 (if available)

Paralogs for ZNF845 Gene

Selected SIMAP similar genes for ZNF845 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZNF845 Gene

genes like me logo Genes that share paralogs with ZNF845: view

Variants for ZNF845 Gene

Sequence variations from dbSNP and Humsavar for ZNF845 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs736155 -- 53,336,694(+) ATTTC(G/T)TTTTT intron-variant
rs749243 -- 53,336,637(+) TCTTT(C/T)TTTTT intron-variant
rs891023 -- 53,337,441(-) GTCAC(C/G)AGACT intron-variant
rs1065225 -- 53,334,194(+) GGTCT(C/T)CCCAC intron-variant
rs1065226 -- 53,334,198(+) TCCCC(A/T)CCGCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF845 Gene

Variant ID Type Subtype PubMed ID
esv2718787 CNV Deletion 23290073
nsv912342 CNV Gain 21882294
esv2718812 CNV Deletion 23290073
nsv912352 CNV Gain 21882294
esv2718816 CNV Deletion 23290073
esv2670793 CNV Deletion 23128226

Relevant External Links for ZNF845 Gene

HapMap Linkage Disequilibrium report
ZNF845

Disorders for ZNF845 Gene

No disorders were found for ZNF845 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF845 Gene

Publications for ZNF845 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PMID: 23000965) Povlsen L.K. … Choudhary C. (Nat. Cell Biol. 2012) 3
  5. Large-scale analysis of lysine SUMOylation by SUMO remnant immunoaffinity profiling. (PMID: 25391492) Lamoliatte F. … Thibault P. (Nat Commun 2014) 3

Products for ZNF845 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF845
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF845
    • Block miRNA regulation of ZNF845 using miScript Target Protectors

    Sources for ZNF845 Gene

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