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Aliases for ZNF844 Gene

Aliases for ZNF844 Gene

  • Zinc Finger Protein 844 2 3

External Ids for ZNF844 Gene

Previous GeneCards Identifiers for ZNF844 Gene

  • GC19P012048
  • GC19P012038
  • GC19P012039
  • GC19P012040
  • GC19P012175
  • GC19P011749

Summaries for ZNF844 Gene

GeneCards Summary for ZNF844 Gene

ZNF844 (Zinc Finger Protein 844) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF709.

UniProtKB/Swiss-Prot for ZNF844 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF844 Gene

Genomics for ZNF844 Gene

Regulatory Elements for ZNF844 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF844 Gene

Chromosome:
19
Start:
12,064,699 bp from pter
End:
12,081,565 bp from pter
Size:
16,867 bases
Orientation:
Plus strand

Genomic View for ZNF844 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for ZNF844 Gene

Proteins for ZNF844 Gene

  • Protein details for ZNF844 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q08AG5-ZN844_HUMAN
    Recommended name:
    Zinc finger protein 844
    Protein Accession:
    Q08AG5
    Secondary Accessions:
    • Q5JPI8

    Protein attributes for ZNF844 Gene

    Size:
    666 amino acids
    Molecular mass:
    76934 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF844 Gene

Proteomics data for ZNF844 Gene at MOPED

Post-translational modifications for ZNF844 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF844 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF844 Gene

Domains & Families for ZNF844 Gene

Gene Families for ZNF844 Gene

Protein Domains for ZNF844 Gene

Suggested Antigen Peptide Sequences for ZNF844 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q08AG5

UniProtKB/Swiss-Prot:

ZN844_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF844: view

Function for ZNF844 Gene

Molecular function for ZNF844 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF844 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF844: view

Animal Model Products

CRISPR Products

miRNA for ZNF844 Gene

miRTarBase miRNAs that target ZNF844

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF844 Gene

Localization for ZNF844 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF844 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF844 Gene COMPARTMENTS Subcellular localization image for ZNF844 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF844 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF844: view

Pathways & Interactions for ZNF844 Gene

SuperPathways for ZNF844 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF844 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF844: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF844 Gene

Drugs & Compounds for ZNF844 Gene

No Compound Related Data Available

Transcripts for ZNF844 Gene

mRNA/cDNA for ZNF844 Gene

(2) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF844 Gene

Zinc finger protein 844:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF844 Gene

No ASD Table

Relevant External Links for ZNF844 Gene

GeneLoc Exon Structure for
ZNF844
ECgene alternative splicing isoforms for
ZNF844

Expression for ZNF844 Gene

mRNA expression in normal human tissues for ZNF844 Gene

Protein differential expression in normal tissues from HIPED for ZNF844 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF844 Gene



SOURCE GeneReport for Unigene cluster for ZNF844 Gene Hs.646391

genes like me logo Genes that share expression patterns with ZNF844: view

Protein tissue co-expression partners for ZNF844 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF844 Gene

Orthologs for ZNF844 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF844 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 38 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 33 (a)
ManyToMany
-- 36
  • 38 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm14288 36
  • 56 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 31 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 40 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 28 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii CR388132.2 36
  • 30 (a)
ManyToMany
CT573234.2 36
  • 29 (a)
ManyToMany
Species with no ortholog for ZNF844:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF844 Gene

ENSEMBL:
Gene Tree for ZNF844 (if available)
TreeFam:
Gene Tree for ZNF844 (if available)

Paralogs for ZNF844 Gene

(636) SIMAP similar genes for ZNF844 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF844: view

Variants for ZNF844 Gene

Sequence variations from dbSNP and Humsavar for ZNF844 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1438694 - 12,076,870(+) ACAGA(A/T)TGCCT reference, missense
rs1561407 -- 12,064,617(-) AGAAG(A/T)CCTGG upstream-variant-2KB
rs1561408 -- 12,064,568(-) CCACA(A/G)TCCAA upstream-variant-2KB
rs2862769 -- 12,070,043(+) GCTTG(A/C)GCCCA intron-variant
rs4608438 -- 12,072,075(+) agaga(C/T)ggggt intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF844 Gene

Variant ID Type Subtype PubMed ID
nsv525966 CNV Gain 19592680
nsv911068 CNV Gain 21882294
nsv911069 CNV Loss 21882294
esv2718190 CNV Deletion 23290073
esv2668294 CNV Deletion 23128226
nsv819366 CNV Loss 19587683
nsv828437 CNV Loss 20364138
nsv828438 CNV Loss 20364138
nsv524284 CNV Loss 19592680

Variation tolerance for ZNF844 Gene

Residual Variation Intolerance Score: 92.92% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 12.81; 94.76% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF844 Gene

HapMap Linkage Disequilibrium report
ZNF844
Human Gene Mutation Database (HGMD)
ZNF844

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF844 Gene

Disorders for ZNF844 Gene

Relevant External Links for ZNF844

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF844
genes like me logo Genes that share disorders with ZNF844: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF844 Gene

Publications for ZNF844 Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  2. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 67
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for ZNF844 Gene

Sources for ZNF844 Gene

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