Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF843 Gene

Aliases for ZNF843 Gene

  • Zinc Finger Protein 843 2 3 5

External Ids for ZNF843 Gene

Previous GeneCards Identifiers for ZNF843 Gene

  • GC16M031355
  • GC16M029007

Summaries for ZNF843 Gene

GeneCards Summary for ZNF843 Gene

ZNF843 (Zinc Finger Protein 843) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

Additional gene information for ZNF843 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF843 Gene

Genomics for ZNF843 Gene

Regulatory Elements for ZNF843 Gene

Enhancers for ZNF843 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16H031451 1.6 Ensembl ENCODE dbSUPER 12.9 -10.7 -10703 4 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF143 FOS PAF1 ENSG00000260740 ZNF843 CLUHP3 HERC2P4 ZNF785 ENSG00000261474 ARMC5
GH16H031456 1.4 ENCODE dbSUPER 10.8 -15.7 -15669 4 HDGF FOXA2 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B SETD1A FUS SRCAP KAT8 ZNF720 ARMC5 ZNF764 ZNF785 C16orf58 ENSG00000260267
GH16H031483 1.1 Ensembl ENCODE 6.3 -41.7 -41652 1 ELF3 MLX ZSCAN4 ARID4B DMAP1 RAD21 RARA MIXL1 EGR2 THAP11 ENSG00000260740 ZNF843 ITGAD SLC5A2
GH16H031427 0.9 ENCODE dbSUPER 6.9 +13.8 13751 4 RING1 L3MBTL2 ZNF740 RNF2 NRF1 MAX MNT ZNF592 TFDP1 SMARCA4 ARMC5 FUS ENSG00000260740 ZNF785 C16orf58 MIR762HG ZNF720 SETD1A PYDC1 PRSS8
GH16H031441 1.3 ENCODE dbSUPER 0.7 +0.3 348 1 HDGF ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 DEK SP3 SP5 SETD1A ZNF747 ENSG00000260740 SRCAP KAT8 LOC647086 RNF40 ENSG00000261474 BCL7C ZNF720
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF843 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF843 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000085346 460 1001 HDGF ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 DEK SP3 SP5

Genomic Location for ZNF843 Gene

Chromosome:
16
Start:
31,432,593 bp from pter
End:
31,443,160 bp from pter
Size:
10,568 bases
Orientation:
Minus strand

Genomic View for ZNF843 Gene

Genes around ZNF843 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF843 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF843 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF843 Gene

Proteins for ZNF843 Gene

  • Protein details for ZNF843 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N446-ZN843_HUMAN
    Recommended name:
    Zinc finger protein 843
    Protein Accession:
    Q8N446
    Secondary Accessions:
    • A8K4U8

    Protein attributes for ZNF843 Gene

    Size:
    348 amino acids
    Molecular mass:
    37065 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF843 Gene

Post-translational modifications for ZNF843 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF843 Gene

No data available for DME Specific Peptides for ZNF843 Gene

Domains & Families for ZNF843 Gene

Gene Families for ZNF843 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF843 Gene

Suggested Antigen Peptide Sequences for ZNF843 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZNF843: view

No data available for UniProtKB/Swiss-Prot for ZNF843 Gene

Function for ZNF843 Gene

Gene Ontology (GO) - Molecular Function for ZNF843 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 22939624
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF843: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ZNF843
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF843 Gene

Localization for ZNF843 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF843 gene
Compartment Confidence
nucleus 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ZNF843 Gene

Pathways & Interactions for ZNF843 Gene

SuperPathways for ZNF843 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF843 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZNF843 Gene

Drugs & Compounds for ZNF843 Gene

No Compound Related Data Available

Transcripts for ZNF843 Gene

mRNA/cDNA for ZNF843 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(246) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF843 Gene

Zinc finger protein 843:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ZNF843
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF843 Gene

No ASD Table

Relevant External Links for ZNF843 Gene

GeneLoc Exon Structure for
ZNF843
ECgene alternative splicing isoforms for
ZNF843

Expression for ZNF843 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF843 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of ZNF843 Gene:

ZNF843

SOURCE GeneReport for Unigene cluster for ZNF843 Gene:

Hs.722243
genes like me logo Genes that share expression patterns with ZNF843: view

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF843 Gene

Orthologs for ZNF843 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF843 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF843 33
  • 99.23 (n)
Species where no ortholog for ZNF843 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF843 Gene

ENSEMBL:
Gene Tree for ZNF843 (if available)
TreeFam:
Gene Tree for ZNF843 (if available)

Paralogs for ZNF843 Gene

genes like me logo Genes that share paralogs with ZNF843: view

No data available for Paralogs for ZNF843 Gene

Variants for ZNF843 Gene

Sequence variations from dbSNP and Humsavar for ZNF843 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000047593 -- 31,435,348(+) CAGTG(A/G)CCTGA downstream-variant-500B
rs1000665144 -- 31,442,896(+) TGCCG(A/G)GGGTC utr-variant-5-prime
rs1000682370 -- 31,435,950(+) CCGGC(C/G)GCTCT reference, synonymous-codon
rs1000905548 -- 31,442,635(+) TCTTA(C/G)CCGGT splice-donor-variant
rs1001087595 -- 31,441,552(+) CCATC(A/G)TGGCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF843 Gene

Variant ID Type Subtype PubMed ID
nsv1066280 CNV gain 25217958
nsv833194 CNV loss 17160897

Variation tolerance for ZNF843 Gene

Gene Damage Index Score: 4.37; 63.47% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF843 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF843

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF843 Gene

Disorders for ZNF843 Gene

Relevant External Links for ZNF843

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF843

No disorders were found for ZNF843 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF843 Gene

Publications for ZNF843 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  3. A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways. (PMID: 25036637) Taipale M … Lindquist S (Cell 2014) 3 60
  4. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PMID: 22939624) Taipale M … Lindquist S (Cell 2012) 3 60
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 60

Products for ZNF843 Gene

Sources for ZNF843 Gene

Content
Loading form....