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Aliases for ZNF841 Gene

Aliases for ZNF841 Gene

  • Zinc Finger Protein 841 2 3 5

External Ids for ZNF841 Gene

Previous GeneCards Identifiers for ZNF841 Gene

  • GC19M057262
  • GC19M052567
  • GC19M048898

Summaries for ZNF841 Gene

GeneCards Summary for ZNF841 Gene

ZNF841 (Zinc Finger Protein 841) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF729.

UniProtKB/Swiss-Prot for ZNF841 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF841 Gene

Genomics for ZNF841 Gene

Regulatory Elements for ZNF841 Gene

Promoters for ZNF841 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF841 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF841 gene promoter:

Genomic Location for ZNF841 Gene

Chromosome:
19
Start:
52,064,363 bp from pter
End:
52,095,773 bp from pter
Size:
31,411 bases
Orientation:
Minus strand

Genomic View for ZNF841 Gene

Genes around ZNF841 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF841 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF841 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF841 Gene

Proteins for ZNF841 Gene

  • Protein details for ZNF841 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZN19-ZN841_HUMAN
    Recommended name:
    Zinc finger protein 841
    Protein Accession:
    Q6ZN19
    Secondary Accessions:
    • B9EG58
    • Q6ZN82
    • Q6ZP71
    • Q8N9U7

    Protein attributes for ZNF841 Gene

    Size:
    808 amino acids
    Molecular mass:
    93148 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04190.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAD18493.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF841 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF841 Gene

Proteomics data for ZNF841 Gene at MOPED

Post-translational modifications for ZNF841 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF841 Gene

No data available for DME Specific Peptides for ZNF841 Gene

Domains & Families for ZNF841 Gene

Gene Families for ZNF841 Gene

Protein Domains for ZNF841 Gene

Suggested Antigen Peptide Sequences for ZNF841 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZN19

UniProtKB/Swiss-Prot:

ZN841_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 23 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 23 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF841: view

Function for ZNF841 Gene

Molecular function for ZNF841 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF841 Gene

genes like me logo Genes that share phenotypes with ZNF841: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF841 Gene

Localization for ZNF841 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF841 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF841 Gene COMPARTMENTS Subcellular localization image for ZNF841 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF841 Gene

Pathways & Interactions for ZNF841 Gene

SuperPathways for ZNF841 Gene

No Data Available

Interacting Proteins for ZNF841 Gene

Gene Ontology (GO) - Biological Process for ZNF841 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZNF841 Gene

Drugs & Compounds for ZNF841 Gene

No Compound Related Data Available

Transcripts for ZNF841 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF841 Gene

No ASD Table

Relevant External Links for ZNF841 Gene

GeneLoc Exon Structure for
ZNF841
ECgene alternative splicing isoforms for
ZNF841

Expression for ZNF841 Gene

mRNA expression in normal human tissues for ZNF841 Gene

Protein differential expression in normal tissues from HIPED for ZNF841 Gene

This gene is overexpressed in Oral epithelium (68.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF841 Gene



genes like me logo Genes that share expression patterns with ZNF841: view

Protein tissue co-expression partners for ZNF841 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF841 Gene

Orthologs for ZNF841 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF841 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF841 35
  • 99.42 (n)
  • 99.13 (a)
ZNF841 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 51 (a)
ManyToMany
-- 36
  • 46 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp51 36
  • 42 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 39 (a)
ManyToMany
-- 36
  • 35 (a)
ManyToMany
-- 36
  • 46 (a)
ManyToMany
-- 36
  • 41 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
CSA.1668 36
  • 35 (a)
ManyToMany
Species with no ortholog for ZNF841:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF841 Gene

ENSEMBL:
Gene Tree for ZNF841 (if available)
TreeFam:
Gene Tree for ZNF841 (if available)

Paralogs for ZNF841 Gene

(545) SIMAP similar genes for ZNF841 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF841: view

Variants for ZNF841 Gene

Sequence variations from dbSNP and Humsavar for ZNF841 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1560690 -- 52,075,094(-) ACTAT(C/T)GTATG intron-variant
rs2043298 -- 52,069,814(-) GAAAT(G/T)GACTT intron-variant
rs2116867 -- 52,072,639(-) GTCTC(A/G)AACTC intron-variant
rs2116868 -- 52,072,579(-) CAGGC(A/G)TGAGC intron-variant
rs4801908 -- 52,071,470(+) CAGGC(A/G)AAGAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF841 Gene

Variant ID Type Subtype PubMed ID
esv638 CNV CNV 17122850
dgv143e55 CNV Gain 17911159
dgv1112e1 CNV Complex 17122850
dgv425n27 CNV Gain 19166990
nsv833872 CNV Loss 17160897
nsv2535 CNV Loss 18451855

Variation tolerance for ZNF841 Gene

Residual Variation Intolerance Score: 23.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.28; 70.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF841 Gene

HapMap Linkage Disequilibrium report
ZNF841

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF841 Gene

Disorders for ZNF841 Gene

Relevant External Links for ZNF841

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF841

No disorders were found for ZNF841 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF841 Gene

Publications for ZNF841 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics. (PMID: 24280104) Wu A.C. … Tantisira K. (J. Allergy Clin. Immunol. 2014) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF841 Gene

Sources for ZNF841 Gene

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