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Aliases for ZNF841 Gene

Aliases for ZNF841 Gene

  • Zinc Finger Protein 841 2 3 5

External Ids for ZNF841 Gene

Previous GeneCards Identifiers for ZNF841 Gene

  • GC19M057262
  • GC19M052567
  • GC19M048898

Summaries for ZNF841 Gene

GeneCards Summary for ZNF841 Gene

ZNF841 (Zinc Finger Protein 841) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF836.

UniProtKB/Swiss-Prot for ZNF841 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF841 Gene

Genomics for ZNF841 Gene

Regulatory Elements for ZNF841 Gene

Enhancers for ZNF841 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G051687 1.8 FANTOM5 ENCODE dbSUPER 35.7 +405.3 405283 6.9 CREB3L1 DMAP1 FEZF1 YY1 ZNF143 ZNF263 SP3 NFYC MEF2D ZNF610 ZNF808 ZNF836 ZNF616 ZNF841 ZNF137P ENSG00000268970 ZNF766 ENSG00000269825 ZNF528 ZNF175
GH19G052137 1.4 FANTOM5 ENCODE 24 -43.9 -43859 3.3 PKNOX1 FOXA2 CREB3L1 ARNT WRNIP1 ARID4B SIN3A DMAP1 YY1 ZNF143 ZNF808 ZNF137P ENSG00000268970 ZNF816 ZNF350 ZNF836 ZNF600 ZNF468 ZNF616 ZNF841
GH19G052047 1.1 ENCODE 21 +46.9 46885 2.1 HDGF PKNOX1 CREB3L1 ARNT ARID4B SIN3A DMAP1 YY1 ZNF143 SP3 ZNF841 ZNF432 ENSG00000275055 ZNF614
GH19G051121 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11.4 +969.6 969638 10.3 PKNOX1 FOXA2 ATF1 ARNT YBX1 ZBTB7B TCF12 GATA2 FOS YY2 SIGLEC9 ZNF841 ZNF577 POLD1 SIGLEC18P KLK11 CTU1 C19orf81 SIGLEC10 CD33
GH19G052026 1.1 ENCODE 16.5 +68.0 67950 2.8 HDGF PKNOX1 FOXA2 CREB3L1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZNF137P ZNF841 ZNF432 ENSG00000268970 ZNF701 ZNF611 ZNF28 ZNF578 ZNF816 ENSG00000269825
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF841 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF841 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000111282 672 2600 ATF1 CREB3L1 ARID4B SIN3A ZNF48 KDM4B ZNF263 SP3 MXD4 NCOA1

Transcription factor binding sites by QIAGEN in the ZNF841 gene promoter:

Genomic Location for ZNF841 Gene

Chromosome:
19
Start:
52,064,363 bp from pter
End:
52,095,773 bp from pter
Size:
31,411 bases
Orientation:
Minus strand

Genomic View for ZNF841 Gene

Genes around ZNF841 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF841 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF841 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF841 Gene

Proteins for ZNF841 Gene

  • Protein details for ZNF841 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZN19-ZN841_HUMAN
    Recommended name:
    Zinc finger protein 841
    Protein Accession:
    Q6ZN19
    Secondary Accessions:
    • B9EG58
    • Q6ZN82
    • Q6ZP71
    • Q8N9U7

    Protein attributes for ZNF841 Gene

    Size:
    808 amino acids
    Molecular mass:
    93148 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04190.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAD18493.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF841 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF841 Gene

Post-translational modifications for ZNF841 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF841 Gene

Domains & Families for ZNF841 Gene

Gene Families for ZNF841 Gene

Protein Domains for ZNF841 Gene

Suggested Antigen Peptide Sequences for ZNF841 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZN19

UniProtKB/Swiss-Prot:

ZN841_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF841: view

Function for ZNF841 Gene

Molecular function for ZNF841 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF841 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF841: view

Phenotypes for ZNF841 Gene

genes like me logo Genes that share phenotypes with ZNF841: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF841 Gene

Localization for ZNF841 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF841 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF841 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF841 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF841: view

Pathways & Interactions for ZNF841 Gene

SuperPathways for ZNF841 Gene

No Data Available

Interacting Proteins for ZNF841 Gene

Gene Ontology (GO) - Biological Process for ZNF841 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA,IEA --
genes like me logo Genes that share ontologies with ZNF841: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF841 Gene

Drugs & Compounds for ZNF841 Gene

No Compound Related Data Available

Transcripts for ZNF841 Gene

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF841 Gene

No ASD Table

Relevant External Links for ZNF841 Gene

GeneLoc Exon Structure for
ZNF841
ECgene alternative splicing isoforms for
ZNF841

Expression for ZNF841 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF841 Gene

Protein differential expression in normal tissues from HIPED for ZNF841 Gene

This gene is overexpressed in Oral epithelium (68.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF841 Gene



Protein tissue co-expression partners for ZNF841 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF841 Gene:

ZNF841

Evidence on tissue expression from TISSUES for ZNF841 Gene

  • Lung(4.3)
  • Heart(4.2)
  • Kidney(4.2)
genes like me logo Genes that share expression patterns with ZNF841: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF841 Gene

Orthologs for ZNF841 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF841 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF841 34 35
  • 99.42 (n)
cow
(Bos Taurus)
Mammalia -- 35
  • 51 (a)
ManyToMany
-- 35
  • 51 (a)
ManyToMany
-- 35
  • 50 (a)
ManyToMany
-- 35
  • 50 (a)
ManyToMany
-- 35
  • 46 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp51 35
  • 42 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 46 (a)
ManyToMany
-- 35
  • 43 (a)
ManyToMany
-- 35
  • 41 (a)
ManyToMany
-- 35
  • 39 (a)
ManyToMany
-- 35
  • 35 (a)
ManyToMany
CSA.1668 35
  • 35 (a)
ManyToMany
Species where no ortholog for ZNF841 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF841 Gene

ENSEMBL:
Gene Tree for ZNF841 (if available)
TreeFam:
Gene Tree for ZNF841 (if available)

Paralogs for ZNF841 Gene

(545) SIMAP similar genes for ZNF841 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF841: view

Variants for ZNF841 Gene

Sequence variations from dbSNP and Humsavar for ZNF841 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000050884 -- 52,051,852(+) CCCTA(A/G)CTCCA intron-variant
rs1000174767 -- 52,076,977(+) TTCCT(G/T)TAGTT intron-variant, nc-transcript-variant, reference, stop-gained
rs1000234411 -- 52,072,055(+) TAAAC(C/T)GATGT intron-variant
rs1000260745 -- 52,072,351(+) ATAAC(A/C)CATCA intron-variant
rs1000402250 -- 52,051,408(+) TGGCC(C/T)ATTTC nc-transcript-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF841 Gene

Variant ID Type Subtype PubMed ID
dgv1067e212 CNV gain 25503493
dgv143e55 CNV gain 17911159
dgv3626n100 CNV gain 25217958
dgv425n27 CNV gain 19166990
dgv6523n54 CNV gain 21841781
esv2758767 CNV gain+loss 17122850
esv3583507 CNV loss 25503493
esv3644684 CNV gain 21293372
nsv1140251 OTHER inversion 24896259
nsv2535 CNV deletion 18451855
nsv833872 CNV loss 17160897
nsv963068 CNV duplication 23825009
nsv978838 CNV duplication 23825009

Variation tolerance for ZNF841 Gene

Residual Variation Intolerance Score: 23.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.28; 70.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF841 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF841

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF841 Gene

Disorders for ZNF841 Gene

Relevant External Links for ZNF841

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF841

No disorders were found for ZNF841 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF841 Gene

Publications for ZNF841 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics. (PMID: 24280104) Wu A.C. … Tantisira K. (J. Allergy Clin. Immunol. 2014) 3 64
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ZNF841 Gene

Sources for ZNF841 Gene

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