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Aliases for ZNF84 Gene

Aliases for ZNF84 Gene

  • Zinc Finger Protein 84 2 3
  • Zinc Finger Protein HPF2 3 4
  • Zinc Finger Protein 84 (HPF2) 2
  • HPF2 3

External Ids for ZNF84 Gene

Previous GeneCards Identifiers for ZNF84 Gene

  • GC12P131135
  • GC12P133187
  • GC12P131801
  • GC12P131390
  • GC12P132224
  • GC12P132124
  • GC12P133613

Summaries for ZNF84 Gene

GeneCards Summary for ZNF84 Gene

ZNF84 (Zinc Finger Protein 84) is a Protein Coding gene. An important paralog of this gene is ZNF630.

UniProtKB/Swiss-Prot for ZNF84 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF84 Gene

Genomics for ZNF84 Gene

Regulatory Elements for ZNF84 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF84 Gene

Start:
133,037,292 bp from pter
End:
133,063,304 bp from pter
Size:
26,013 bases
Orientation:
Plus strand

Genomic View for ZNF84 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF84 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF84 Gene

Proteins for ZNF84 Gene

  • Protein details for ZNF84 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P51523-ZNF84_HUMAN
    Recommended name:
    Zinc finger protein 84
    Protein Accession:
    P51523
    Secondary Accessions:
    • B2RAK5
    • D3DXJ1
    • Q3ZCV9
    • Q5D057
    • Q86XU8
    • Q9NNX7
    • Q9UC17
    • Q9UC18

    Protein attributes for ZNF84 Gene

    Size:
    738 amino acids
    Molecular mass:
    85457 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF84 Gene

Proteomics data for ZNF84 Gene at MOPED

Post-translational modifications for ZNF84 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF84 Gene

Domains for ZNF84 Gene

Gene Families for ZNF84 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF84 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P51523

UniProtKB/Swiss-Prot:

ZNF84_HUMAN :
  • P51523
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 19 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF84: view

Function for ZNF84 Gene

Molecular function for ZNF84 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF84 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding NAS 2505992
GO:0008270 zinc ion binding NAS 2505992
GO:0046872 metal ion binding --
genes like me logo Genes that share ontologies with ZNF84: view

Animal Model Products

CRISPR Products

miRNA for ZNF84 Gene

miRTarBase miRNAs that target ZNF84

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF84 Gene

Localization for ZNF84 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF84 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF84 Gene COMPARTMENTS Subcellular localization image for ZNF84 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF84 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF84: view

Pathways for ZNF84 Gene

SuperPathways for ZNF84 Gene

No Data Available

Interacting Proteins for ZNF84 Gene

Gene Ontology (GO) - Biological Process for ZNF84 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF84: view

No data available for Pathways by source for ZNF84 Gene

Transcripts for ZNF84 Gene

Unigene Clusters for ZNF84 Gene

Zinc finger protein 84:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF84

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF84 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d · 5e ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d · 8e ^ 9
SP1: - - - - - - -
SP2: - - - - - - - - -
SP3: - - - - - - - -
SP4: - - - - - - - - - -
SP5: - - - - - - - - - - - - -
SP6: - - - - - - -
SP7: - - - - -
SP8: - - - - - -
SP9: - - - - -
SP10: - - - - -
SP11: - -
SP12: - -
SP13:

Relevant External Links for ZNF84 Gene

GeneLoc Exon Structure for
ZNF84
ECgene alternative splicing isoforms for
ZNF84

Expression for ZNF84 Gene

mRNA expression in normal human tissues for ZNF84 Gene

SOURCE GeneReport for Unigene cluster for ZNF84 Gene Hs.445019

genes like me logo Genes that share expressions with ZNF84: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF84 Gene

Orthologs for ZNF84 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF84 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF84 35
  • 99.64 (n)
  • 100 (a)
ZNF84 36
  • 100 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 36
  • 83 (a)
OneToMany
ZNF84 35
  • 89.57 (n)
  • 90.2 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 83 (a)
OneToMany
ZNF26 35
  • 88.89 (n)
  • 89.97 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8319 37
  • 37 (a)
BG:DS02740.8 37
  • 37 (a)
CG18555 37
  • 40 (a)
CG11247 37
  • 37 (a)
CG3485 37
  • 44 (a)
CG8301 37
  • 31 (a)
CG15436 37
  • 42 (a)
CG18011 37
  • 25 (a)
Kr 37
  • 49 (a)
CG5245 37
  • 41 (a)
CG12299 37
  • 40 (a)
CG10543 37
  • 33 (a)
CG11762 37
  • 39 (a)
Neu2 37
  • 36 (a)
CG7987 37
  • 31 (a)
CG14711 37
  • 50 (a)
CG18476 37
  • 30 (a)
crol 37
  • 43 (a)
worm
(Caenorhabditis elegans)
Secernentea M03D4.4 37
  • 32 (a)
Species with no ortholog for ZNF84:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for ZNF84 Gene

ENSEMBL:
Gene Tree for ZNF84 (if available)
TreeFam:
Gene Tree for ZNF84 (if available)

Paralogs for ZNF84 Gene

Selected SIMAP similar genes for ZNF84 Gene using alignment to 9 proteins:

Pseudogenes.org Pseudogenes for ZNF84 Gene

genes like me logo Genes that share paralogs with ZNF84: view

Variants for ZNF84 Gene

Sequence variations from dbSNP and Humsavar for ZNF84 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs11297 -- 133,063,073(+) TGTGG(A/G)TGCAG utr-variant-3-prime
rs1142650 -- 133,040,358(+) ggagt(C/T)tgaga intron-variant
rs2230099 -- 133,057,312(+) CATAG(A/G)AATCG reference, synonymous-codon
rs7136706 -- 133,042,337(+) aaatc(G/T)attca intron-variant
rs7138888 -- 133,061,472(+) aaaga(A/C)aagaa utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF84 Gene

Variant ID Type Subtype PubMed ID
dgv538e1 CNV Complex 17122850
dgv330e199 CNV Deletion 23128226
nsv525745 CNV Gain 19592680
nsv899835 CNV Loss 21882294
nsv9048 CNV Gain 18304495
nsv899836 CNV Gain 21882294
esv27162 CNV Gain+Loss 19812545
nsv9049 CNV Gain 18304495
essv8522 CNV CNV 17122850

Relevant External Links for ZNF84 Gene

HapMap Linkage Disequilibrium report
ZNF84

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF84 Gene

Disorders for ZNF84 Gene

No disorders were found for ZNF84 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF84 Gene

Publications for ZNF84 Gene

  1. Members of the zinc finger protein gene family sharing a conserved N- terminal module. (PMID: 1945843) Rosati M. … Grimaldi G. (Nucleic Acids Res. 1991) 3 4
  2. The human genome contains hundreds of genes coding for finger proteins of the Kruppel type. (PMID: 2505992) Bellefroid E.J. … Martial J.A. (DNA 1989) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF84 Gene

Sources for ZNF84 Gene

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