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Aliases for ZNF839 Gene

Aliases for ZNF839 Gene

  • Zinc Finger Protein 839 2 3 5
  • Renal Carcinoma Antigen NY-REN-50 3 4
  • C14orf131 3 4
  • Chromosome 14 Open Reading Frame 131 2

External Ids for ZNF839 Gene

Previous HGNC Symbols for ZNF839 Gene

  • C14orf131

Previous GeneCards Identifiers for ZNF839 Gene

  • GC14P101855
  • GC14P102786
  • GC14P082969
  • GC14P102318
  • GC14P102381
  • GC14P102452

Summaries for ZNF839 Gene

GeneCards Summary for ZNF839 Gene

ZNF839 (Zinc Finger Protein 839) is a Protein Coding gene. Among its related pathways are Gene Expression.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF839 Gene

Genomics for ZNF839 Gene

Regulatory Elements for ZNF839 Gene

Enhancers for ZNF839 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F102313 0.7 ENCODE 12.2 -3.0 -3019 1.2 ARID4B SIN3A DMAP1 ZNF2 ZNF143 ZNF207 ZNF263 SP5 MXD4 REST ZNF839 RCOR1 ENSG00000271780 CINP TECPR2 ENSG00000272444 TRI-AAT5-4 MOK
GH14F102315 0.5 Ensembl ENCODE 11.4 +2.4 2414 7.7 HDGF PKNOX1 MLX WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 RCOR1 CINP TECPR2 RPL26P4 ZNF839 CDC42BPB ENSG00000258959 ENSG00000259515 ENSG00000271780 GC14P102747
GH14F102084 1.5 FANTOM5 Ensembl ENCODE 11.1 -230.6 -230646 5.1 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 HSP90AA1 RPL26P4 WDR20 ZNF839 CDC42BPB RCOR1 MOK PIR41764 GC14P102751
GH14F102094 0.8 Ensembl ENCODE 10.4 -220.8 -220814 3.5 PKNOX1 WRNIP1 ARID4B SIN3A RAD21 RFX5 GLIS2 ZNF143 RCOR1 ETV6 WDR20 HSP90AA1 ZNF839 MOK GC14P102751 PIR41764
GH14F102217 0.4 ENCODE 9.1 -98.8 -98835 1.4 PKNOX1 SAP130 FOXA3 DMAP1 ZIC2 KMT2B TGIF2 ZGPAT ZFHX2 PBX2 MOK HSP90AA1 WDR20 ZNF839 ENSG00000271780 PIR59893 GC14M102234
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZNF839 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF839 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001625355 -177 1601 PKNOX1 MLX WRNIP1 ARID4B SIN3A ZNF2 YY1 ZNF143 ZNF207 FOS

Genomic Location for ZNF839 Gene

Chromosome:
14
Start:
102,317,377 bp from pter
End:
102,343,174 bp from pter
Size:
25,798 bases
Orientation:
Plus strand

Genomic View for ZNF839 Gene

Genes around ZNF839 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF839 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF839 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF839 Gene

Proteins for ZNF839 Gene

  • Protein details for ZNF839 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8K0R7-ZN839_HUMAN
    Recommended name:
    Zinc finger protein 839
    Protein Accession:
    A8K0R7
    Secondary Accessions:
    • B3KSD2
    • Q53FH5
    • Q6GPI5
    • Q86TU1
    • Q9BQ86
    • Q9NUU3

    Protein attributes for ZNF839 Gene

    Size:
    811 amino acids
    Molecular mass:
    87484 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA92026.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAD62594.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF839 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF839 Gene

Post-translational modifications for ZNF839 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF839 Gene

Domains & Families for ZNF839 Gene

Protein Domains for ZNF839 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

A8K0R7

UniProtKB/Swiss-Prot:

ZN839_HUMAN :
  • Contains 1 C2H2-type zinc finger.
Similarity:
  • Contains 1 C2H2-type zinc finger.
genes like me logo Genes that share domains with ZNF839: view

No data available for Gene Families for ZNF839 Gene

Function for ZNF839 Gene

Gene Ontology (GO) - Molecular Function for ZNF839 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF839: view
genes like me logo Genes that share phenotypes with ZNF839: view

Animal Model Products

miRNA for ZNF839 Gene

miRTarBase miRNAs that target ZNF839

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF839 Gene

Localization for ZNF839 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF839 Gene COMPARTMENTS Subcellular localization image for ZNF839 gene
Compartment Confidence
nucleus 4
cytosol 2
plasma membrane 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZNF839 Gene

Pathways & Interactions for ZNF839 Gene

SuperPathways for ZNF839 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF839: view

Pathways by source for ZNF839 Gene

2 Reactome pathways for ZNF839 Gene

Interacting Proteins for ZNF839 Gene

Gene Ontology (GO) - Biological Process for ZNF839 Gene

None

No data available for SIGNOR curated interactions for ZNF839 Gene

Transcripts for ZNF839 Gene

Unigene Clusters for ZNF839 Gene

Zinc finger protein 839:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF839 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11
SP1: - - - -
SP2: - -
SP3: - - - -
SP4: -
SP5: -
SP6: - -
SP7: -
SP8:

Relevant External Links for ZNF839 Gene

GeneLoc Exon Structure for
ZNF839
ECgene alternative splicing isoforms for
ZNF839

Expression for ZNF839 Gene

mRNA expression in normal human tissues for ZNF839 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF839 Gene



NURSA nuclear receptor signaling pathways regulating expression of ZNF839 Gene:

ZNF839

SOURCE GeneReport for Unigene cluster for ZNF839 Gene:

Hs.743359
genes like me logo Genes that share expression patterns with ZNF839: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF839 Gene

Orthologs for ZNF839 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF839 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF839 34 35
  • 98.4 (n)
dog
(Canis familiaris)
Mammalia ZNF839 34 35
  • 76.18 (n)
rat
(Rattus norvegicus)
Mammalia Zfp839 34
  • 67.8 (n)
mouse
(Mus musculus)
Mammalia Zfp839 34 16 35
  • 67.29 (n)
cow
(Bos Taurus)
Mammalia ZNF839 35
  • 61 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF839 35
  • 37 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF839 35
  • 37 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF839 35
  • 36 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF839 35
  • 42 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii znf839 35
  • 21 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.453 35
  • 15 (a)
OneToOne
Species where no ortholog for ZNF839 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF839 Gene

ENSEMBL:
Gene Tree for ZNF839 (if available)
TreeFam:
Gene Tree for ZNF839 (if available)

Paralogs for ZNF839 Gene

(2) SIMAP similar genes for ZNF839 Gene using alignment to 8 proteins:

Pseudogenes.org Pseudogenes for ZNF839 Gene

genes like me logo Genes that share paralogs with ZNF839: view

No data available for Paralogs for ZNF839 Gene

Variants for ZNF839 Gene

Sequence variations from dbSNP and Humsavar for ZNF839 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs10131902 -- 102,323,959(+) aagtt(C/G)cagga intron-variant, upstream-variant-2KB
rs10132183 -- 102,324,469(+) ACCTG(A/G)GAGGC intron-variant, upstream-variant-2KB
rs10134464 -- 102,337,429(+) cttcc(A/G)aagtg intron-variant
rs10135337 -- 102,316,169(+) CTCTT(G/T)TTTTG upstream-variant-2KB
rs10137387 -- 102,338,290(+) CCCAA(C/T)ACTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF839 Gene

Variant ID Type Subtype PubMed ID
esv29657 CNV gain 19812545
esv3635547 CNV gain 21293372
nsv1131164 CNV deletion 24896259
nsv827062 CNV gain 20364138
nsv827063 CNV gain 20364138

Variation tolerance for ZNF839 Gene

Residual Variation Intolerance Score: 97.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.22; 81.05% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF839 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF839

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF839 Gene

Disorders for ZNF839 Gene

Relevant External Links for ZNF839

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF839

No disorders were found for ZNF839 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF839 Gene

Publications for ZNF839 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 64
  3. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S. … Ideker T. (Nat. Methods 2010) 3 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 4 64

Products for ZNF839 Gene

Sources for ZNF839 Gene

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